{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:25:10Z","timestamp":1760660710725,"version":"build-2065373602"},"reference-count":46,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.jnutbio.2009.01.021","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T05:10:13Z","timestamp":1241759413000},"page":"418-423","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Mukitake mushroom (Panellus serotinus) alleviates nonalcoholic fatty liver disease through the suppression of monocyte chemoattractant protein 1 production in db\/db mice"],"prefix":"10.1016","volume":"21","author":[{"given":"Koji","family":"Nagao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nao","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Inafuku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bungo","family":"Shirouchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Morooka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Nagamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruyoshi","family":"Yanagita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2009.01.021_bib1","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1152\/physrev.1994.74.4.761","article-title":"Regional adiposity and morbidity","volume":"74","author":"Kissebah","year":"1994","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib2","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S1521-6918(04)00091-5","article-title":"Obesity: epidemiology and clinical aspects","volume":"18","author":"Formiguera","year":"2004","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib3","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/j.1440-1746.2006.04781.x","article-title":"Effects of nonalcoholic fatty liver disease on the development of metabolic disorders","volume":"22","author":"Fan","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib4","first-page":"3","article-title":"Fat and the liver \u2014 a molecular overview","volume":"13","author":"Harrison","year":"2002","journal-title":"Semin Gastrointest Dis"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib5","first-page":"17","article-title":"Diabetes mellitus, obesity, and hepatic steatosis","volume":"13","author":"Youssef","year":"2002","journal-title":"Semin Gastrointest Dis"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/jhep.2000.8978","article-title":"Metabolic and nutritional considerations in nonalcoholic fatty liver","volume":"32","author":"Fong","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib7","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1126\/science.153.3740.1127","article-title":"Diabetes, a new mutation in the mouse","volume":"153","author":"Hummel","year":"1966","journal-title":"Science"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib8","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(00)81294-5","article-title":"Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db\/db mice","volume":"84","author":"Chen","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib9","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/379632a0","article-title":"Abnormal splicing of the leptin receptor in diabetic mice","volume":"379","author":"Lee","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.plipres.2007.12.002","article-title":"Bioactive lipids in metabolic syndrome","volume":"47","author":"Nagao","year":"2008","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib11","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1021\/jf703578d","article-title":"Dietary phosphatidylinositol prevents the development of nonalcoholic fatty liver disease in Zucker (fa\/fa) rats","volume":"56","author":"Shirouchi","year":"2008","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib12","doi-asserted-by":"crossref","first-page":"7170","DOI":"10.1021\/jf071225x","article-title":"Effect of dietary omega 3 phosphatidylcholine on obesity-related disorders in obese Otsuka Long\u2013Evans Tokushima Fatty rats","volume":"55","author":"Shirouchi","year":"2007","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/jn\/135.1.9","article-title":"Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa\/fa) rats","volume":"135","author":"Nagao","year":"2005","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib14","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1111\/j.1753-4887.1996.tb03825.x","article-title":"Functional properties of edible mushrooms","volume":"54","author":"Chang","year":"1996","journal-title":"Nutr Rev"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib15","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s00253-002-1076-7","article-title":"Medical mushrooms as a source of antitumor and immunomodulating polysaccharides","volume":"60","author":"Wasser","year":"2002","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib16","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3177\/jnsv.48.73","article-title":"Effect of hatakeshimeji (Lyophyllum decastes Sing.) mushroom on serum lipid levels in rats","volume":"8","author":"Ukawa","year":"2002","journal-title":"J Nutr Sci Vitaminol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib17","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00253-004-1787-z","article-title":"Medical mushroom modulators of molecular targets as cancer therpeutics","volume":"67","author":"Zaidman","year":"2005","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib18","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1248\/bpb.29.1651","article-title":"Protection against d-galactosamine-induced acute liver injury by oral administration of extracts from Lentinus edodes mycelia","volume":"29","author":"Watanabe","year":"2006","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3177\/jnsv.53.293","article-title":"Oral administration of the extract from Hatakeshimeji (Lyophyllum decastes Sing.) mushroom inhibits the development of atopic dermatitis-like skin lesions in NC\/Nga mice","volume":"53","author":"Ukawa","year":"2007","journal-title":"J Nutr Sci Vitaminol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib20","first-page":"146","article-title":"Simple equipment cultivation of Panellus serotinus","volume":"60","author":"Nagamori","year":"2007","journal-title":"Kyushu J Forrest Res"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib21","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/jn\/107.7.1340","article-title":"Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies","volume":"107","author":"American Institute of Nutrition","year":"1977","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib22","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipids from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib23","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0009-8981(68)90041-7","article-title":"A colorimetric method for estimating serum triglycerides","volume":"22","author":"Fletcher","year":"1968","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0021-9258(19)50934-6","article-title":"A revision of the Schoenheimer-Sperry method for cholesterol determination","volume":"187","author":"Sperry","year":"1950","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1042\/bj2350087","article-title":"Effect of prior nutritional status on the activity of lipogenic enzymes in primary monolayer cultures of rat hepatocytes","volume":"235","author":"Kelley","year":"1986","journal-title":"Biochem J"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib26","first-page":"323","article-title":"Malic enzyme: malic enzymes from pigeon and wheat germ","volume":"1","author":"Ochoa","year":"1995","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib27","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1016\/S0021-9258(19)43946-X","article-title":"The subcellular distribution of carnitine acyltransferases in mammalian liver and kidney","volume":"248","author":"Markwell","year":"1973","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib29","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1210\/jcem.84.5.5661","article-title":"Liver pathology and the metabolic syndrome X in severe obesity","volume":"84","author":"Marceau","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib30","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.2337\/diabetes.50.8.1844","article-title":"Nonalcoholic fatty liver disease: a feature of the metabolic syndrome","volume":"50","author":"Marchesini","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib31","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1053\/jhep.2003.50161","article-title":"Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome","volume":"37","author":"Marchesini","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib32","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/ncpcardio0380","article-title":"Therapy Insight: adipocytokines in metabolic syndrome and related cardiovascular disease","volume":"3","author":"Matsuzawa","year":"2006","journal-title":"Nat Clin Pract Cardiovasc Med"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1172\/JCI200317797","article-title":"The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver disease in mice","volume":"112","author":"Xu","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib34","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1046\/j.1365-2265.2004.01977.x","article-title":"Adiponectin, hepatocellular dysfunction and insulin sensitivity","volume":"60","author":"Lopez-Bermejo","year":"2004","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib35","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1210\/jc.2003-031315","article-title":"Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated Type 2 diabetes patients","volume":"89","author":"Bajaj","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib36","doi-asserted-by":"crossref","first-page":"795","DOI":"10.2337\/db06-1039","article-title":"Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression","volume":"56","author":"Kanatani","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib37","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1038\/nm788","article-title":"Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase","volume":"8","author":"Yamauchi","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib38","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1074\/jbc.M209033200","article-title":"Globular adiponectin protected ob\/ob mice from diabetes and ApoE-deficient mice from atherosclerosis","volume":"278","author":"Yamauchi","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib39","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0016-5085(98)70599-2","article-title":"Steatohepatitis: a tale of two \u201chits\u201d?","volume":"114","author":"Day","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib40","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/33340","article-title":"Chemokines and leukocyte traffic","volume":"392","author":"Baggiolini","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib41","doi-asserted-by":"crossref","first-page":"7265","DOI":"10.1073\/pnas.1133870100","article-title":"Monocyte chemoattractant protein 1 in obesity and insulin resistance","volume":"100","author":"Sartipy","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib42","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1172\/JCI26498","article-title":"MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity","volume":"116","author":"Kanda","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib43","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nm724","article-title":"Diet-induced insulin resistance in mice lacking adiponectin\/ACRP30","volume":"8","author":"Maeda","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib44","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1016\/S0092-8674(02)00703-1","article-title":"Missing pieces in the NF-\u03baB puzzle","volume":"109","author":"Ghosh","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib45","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1172\/JCI11559","article-title":"Prevention of fat-induced insulin resistance by salicylate","volume":"108","author":"Kim","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2009.01.021_bib46","first-page":"299","article-title":"Fungal metabolites modulating NF-\u03baB activity: an approach to cancer therapy and chemoprevention","volume":"19","author":"Petrova","year":"2008","journal-title":"Oncol Rep"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286309000321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286309000321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:01:47Z","timestamp":1760626907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286309000321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0955286309000321"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2009.01.021","relation":{},"ISSN":["0955-2863"],"issn-type":[{"type":"print","value":"0955-2863"}],"subject":[],"published":{"date-parts":[[2010,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mukitake mushroom (Panellus serotinus) alleviates nonalcoholic fatty liver disease through the suppression of monocyte chemoattractant protein 1 production in db\/db mice","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2009.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}