{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:34:18Z","timestamp":1792647258918,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.jnutbio.2013.01.009","type":"journal-article","created":{"date-parts":[[2013,4,22]],"date-time":"2013-04-22T12:36:56Z","timestamp":1366634216000},"page":"1587-1595","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":186,"title":["Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6\/J mice"],"prefix":"10.1016","volume":"24","author":[{"given":"Banrida","family":"Wahlang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Cameron","family":"Falkner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Gregory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Ansert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Conklin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aruni","family":"Bhatnagar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig J.","family":"McClain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Cave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2013.01.009_bb0005","series-title":"Zakim and Boyer\u2019s Hepatology: A Textbook of Liver Disease","first-page":"476","article-title":"Occupational and environmental liver disease","author":"Cave","year":"2011"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0010","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1478-3231.1999.tb00053.x","article-title":"Nonalcoholic steatohepatitis: a toxic liver disease in industrial workers","volume":"19","author":"Cotrim","year":"1999","journal-title":"Liver"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0015","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/hep.23321","article-title":"Toxicant-associated steatohepatitis in vinyl chloride workers","volume":"51","author":"Cave","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0020","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1097\/JOM.0b013e31822cfd68","article-title":"Serum cytokeratin 18 and cytokine elevations suggest a high prevalence of occupational liver disease in highly exposed elastomer\/polymer workers","volume":"53","author":"Cave","year":"2011","journal-title":"J Occup Environ Med"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0025","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1289\/ehp.1002720","article-title":"Polychlorinated biphenyls, lead, and mercury are associated with liver disease in american adults: NHANES 2003\u20132004","volume":"118","author":"Cave","year":"2010","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0030","first-page":"120","article-title":"Circulating levels of persistant organic pollutants associate in divergent ways to fat mass measured by DXA in humans. The toxicologist CD supplement to toxicological sciences","author":"Ronn","year":"2011","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0035","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00125-007-0755-4","article-title":"Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results from the National Health and Nutrition Examination Survey 1999\u20132002","volume":"50","author":"Lee","year":"2007","journal-title":"Diabetologia"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0040","doi-asserted-by":"crossref","first-page":"e10746","DOI":"10.1371\/journal.pone.0010746","article-title":"An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus","volume":"5","author":"Patel","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0045","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.2337\/dc06-0543","article-title":"A strong dose\u2013response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999\u20132002","volume":"29","author":"Lee","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0050","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1289\/ehp.0800012","article-title":"Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population","volume":"117","author":"Uemura","year":"2009","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0055","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/(SICI)1097-0274(199702)31:2<172::AID-AJIM6>3.0.CO;2-1","article-title":"Increased mortality from chronic liver disease and cirrhosis 13 years after the Taiwan \u201cyucheng\u201d (\u201coil disease\u201d) incident","volume":"31","author":"Yu","year":"1997","journal-title":"Am J Ind Med"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0060","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0048-9697(01)01075-0","article-title":"Towards a global historical emission inventory for selected PCB congeners\u2013a mass balance approach. 1. Global production and consumption","volume":"290","author":"Breivik","year":"2002","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0065","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1289\/ehp.0901347","article-title":"Perfluorinated compounds, polychlorinated biphenyl, and organochlorine pesticide contamination in composite food samples from Dallas, Texas","volume":"118","author":"Schecter","year":"2010","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1289\/ehp.7280","article-title":"Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor","volume":"113","author":"Hennig","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0075","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1053\/j.gastro.2010.03.033","article-title":"A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis","volume":"139","author":"Lee","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0080","first-page":"1","article-title":"NTP toxicology and carcinogenesis studies of a binary mixture of 3,3\u2032,4,4\u2032,5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and 2,2\u2032,4,4\u2032,5,5\u2032-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague\u2013Dawley rats (Gavage Studies)","author":"NTP","year":"2006","journal-title":"Natl Toxicol Program Tech Rep Ser"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0085","first-page":"4","article-title":"NTP technical report on the toxicology and carcinogenesis studies of 2,2\u2032,4,4\u2032,5,5\u2032-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague\u2013Dawley rats (Gavage studies)","author":"NTP","year":"2006","journal-title":"Natl Toxicol Program Tech Rep Ser"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0090","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1289\/ehp.9549","article-title":"Using nutrition for intervention and prevention against environmental chemical toxicity and associated diseases","volume":"115","author":"Hennig","year":"2007","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0095","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jnutbio.2006.12.006","article-title":"Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition","volume":"18","author":"Cave","year":"2007","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0100","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.1021\/pr300297z","article-title":"Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease","volume":"11","author":"Shi","year":"2012","journal-title":"J Proteome Res"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0105","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0110","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/y59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can J Biochem Physiol"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0115","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0120","first-page":"4","article-title":"NTP toxicology and carcinogenesis studies of 3,3\u2032,4,4\u2032,5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague\u2013Dawley rats (Gavage Studies)","author":"NTP","year":"2006","journal-title":"Natl Toxicol Program Tech Rep Ser"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0125","first-page":"1","article-title":"Toxicology and carcinogenesis studies of 2,3\u2032,4,4\u2032,5-pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in female harlan Sprague\u2013Dawley rats (gavage studies)","author":"NTP","year":"2010","journal-title":"Natl Toxicol Program Tech Rep Ser"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0130","doi-asserted-by":"crossref","first-page":"7931","DOI":"10.1128\/MCB.24.18.7931-7940.2004","article-title":"Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes","volume":"24","author":"Kodama","year":"2004","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0135","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.tips.2012.07.003","article-title":"Targeting xenobiotic receptors PXR and CAR for metabolic diseases","volume":"33","author":"Gao","year":"2012","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0140","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.taap.2012.05.016","article-title":"Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner","volume":"263","author":"Al-Salman","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0145","doi-asserted-by":"crossref","unstructured":"Lee DH, Steffes MW, Sjodin A, Jones RS, Needham LL, Jacobs DR, Jr. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One 2011;6:e15977.","DOI":"10.1371\/journal.pone.0015977"},{"issue":"1","key":"10.1016\/j.jnutbio.2013.01.009_bb0150","first-page":"743A","article-title":"Polychlorinated biphenols (PCB) induce tumor necrosis factor \u03b1 (TNF\u03b1) production in RAW 264.7 cells [abstract]. The toxicologist CD supplement to toxicological sciences","volume":"114","author":"Kershner","year":"2010","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.jnutbio.2013.01.009_bb0155","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1289\/ehp.1002830","article-title":"Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides","volume":"119","author":"Goncharov","year":"2011","journal-title":"Environ Health Perspect"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286313000338?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286313000338?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:09:53Z","timestamp":1760627393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286313000338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0955286313000338"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2013.01.009","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6\/J mice","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2013.01.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}