{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:35:20Z","timestamp":1783686920294,"version":"3.55.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T00:00:00Z","timestamp":1607904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jnutbio.2020.108563","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T07:13:57Z","timestamp":1608016437000},"page":"108563","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Zinc salicylate reduces airway smooth muscle cells remodelling by blocking mTOR and activating p21(Waf1\/Cip1)"],"prefix":"10.1016","volume":"89","author":[{"given":"Lei","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8139-2821","authenticated-orcid":false,"given":"Michael","family":"Roth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong Teck","family":"S\u2019ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Tamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ba Xuan","family":"Hoang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2020.108563_bib0001","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0140-6736(17)33311-1","article-title":"Asthma","volume":"391","author":"Papi","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0002","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1055\/s-0037-1618568","article-title":"Epidemiology of asthma and influence of ethnicity","volume":"39","author":"Moraes","year":"2018","journal-title":"Semin Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0003","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1164\/rccm.201611-2248ST","article-title":"ATS assembly on respiratory structure and function. An Official American Thoracic Society Research Statement: current challenges facing research and therapeutic advances in airway remodeling","volume":"195","author":"Prakash","year":"2017","journal-title":"Am J Respir Crit Care Med."},{"key":"10.1016\/j.jnutbio.2020.108563_bib0004","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1164\/rccm.201507-1404OC","article-title":"Bronchial smooth muscle remodeling in nonsevere asthma","volume":"193","author":"Girodet","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0005","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1164\/rccm.201110-1849OC","article-title":"Airway smooth muscle hypertrophy and hyperplasia in asthma","volume":"185","author":"James","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0006","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1111\/cea.12156","article-title":"The relationship between eosinophilia and airway remodelling in mild asthma","volume":"43","author":"Wilson","year":"2013","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0007","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1164\/ajrccm.164.3.2010109","article-title":"Airway smooth muscle cell proliferation is increased in asthma","volume":"164","author":"Johnson","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0008","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1084\/jem.20070956","article-title":"Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma","volume":"204","author":"Trian","year":"2007","journal-title":"J Exp Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0009","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.jaci.2015.10.031","article-title":"Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients","volume":"137","author":"Trian","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0010","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1056\/NEJMoa021660","article-title":"Dysfunctional interaction of C\/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells","volume":"351","author":"Roth","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0011","doi-asserted-by":"crossref","first-page":"41598","DOI":"10.1038\/srep41598","article-title":"Genome-wide regulatory roles of the C2H2-type Zinc finger protein ZNF764 on the glucocorticoid receptor","volume":"7","author":"Fadda","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0012","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1093\/nar\/20.5.1045","article-title":"DNA binding analysis of glucocorticoid receptor specificity mutants","volume":"20","author":"Alroy","year":"1992","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0013","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1016\/j.jnutbio.2013.06.002","article-title":"Zinc regulation of transcriptional activity during retinoic acid-induced neuronal differentiation","volume":"24","author":"Morris","year":"2013","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0014","doi-asserted-by":"crossref","first-page":"6685","DOI":"10.4081\/pr.2016.6685","article-title":"Zinc supplementation in children with asthma exacerbation","volume":"8","author":"Rerksuppaphol","year":"2016","journal-title":"Pediatr Rep"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0015","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.2500\/aap.2016.37.3920","article-title":"Antioxidant supplementation and exhaled nitric oxide in children with asthma","volume":"37","author":"Tenero","year":"2016","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0016","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1111\/all.12729","article-title":"Maternal nutrition during pregnancy and risk of asthma, wheeze, and atopic diseases during childhood: a systematic review and meta-analysis","volume":"70","author":"Beckhaus","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0017","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.biocel.2016.02.004","article-title":"TLR-7 agonist attenuates airway reactivity and inflammation through Nrf2-mediated antioxidant protection in a murine model of allergic asthma","volume":"73","author":"Nadeem","year":"2016","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0018","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/hmg\/ddu479","article-title":"Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB\/ORMDL3 locus","volume":"24","author":"Acevedo","year":"2015","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0019","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.etap.2011.11.002","article-title":"The supplementation of zinc increased the apoptosis of airway smooth muscle cells by increasing p38 phosphorylation","volume":"33","author":"Chiou","year":"2012","journal-title":"Environ Toxicol Pharmacol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0020","doi-asserted-by":"crossref","first-page":"40289","DOI":"10.1074\/jbc.M406063200","article-title":"Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1","volume":"279","author":"Midgley","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0021","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1093\/nar\/29.5.1027","article-title":"Sp1 phosphorylation regulates inducible expression of platelet-derived growth factor B-chain gene via atypical protein kinase C-zeta","volume":"29","author":"Rafty","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0022","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.yexcr.2016.05.014","article-title":"Shh mediates PDGF-induced contractile-to-synthetic phenotypic modulation in vascular smooth muscle cells through regulation of KLF4","volume":"345","author":"Zeng","year":"2016","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0023","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1096\/fj.12-210302","article-title":"Zinc finger motif-1 antagonizes PDGF-BB-induced growth and dedifferentiation of vascular smooth muscle cells","volume":"26","author":"Cattaruzza","year":"2012","journal-title":"FASEB J"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0024","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12931-015-0240-4","article-title":"Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection","volume":"16","author":"Papakonstantinou","year":"2015","journal-title":"Respir Res"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0025","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.chest.2016.08.1440","article-title":"Systemic biomarkers of collagen and elastin turnover are associated with clinically relevant outcomes in COPD","volume":"151","author":"Stolz","year":"2017","journal-title":"Chest"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0026","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.2174\/092986708785747490","article-title":"Structural bases for substrate and inhibitor recognition by matrix metalloproteinases","volume":"15","author":"Aureli","year":"2008","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0027","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1183\/09031936.00146510","article-title":"Series \"matrix metalloproteinases in lung health and disease\": biological role of matrix metalloproteinases: a critical balance","volume":"38","author":"L\u00f6ffek","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0028","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/bs.pmbts.2017.02.003","article-title":"Matrix metalloproteinases in remodeling of lower extremity veins and chronic venous disease","volume":"147","author":"Chen","year":"2017","journal-title":"Prog Mol Biol Transl Sci"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0029","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jaci.2016.11.013","article-title":"Constitutive high expression of protein arginine methyltransferase 1 in asthmatic airway smooth muscle cells is caused by reduced microRNA-19a expression and leads to enhanced remodeling","volume":"140","author":"Sun","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210702","article-title":"Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells","volume":"14","author":"Roth","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0031","article-title":"Bronchial thermoplasty blocks epithelial cell driven airway wall remodelling","author":"Sun","year":"2019","journal-title":"Europ Respir J"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0032","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.bcp.2014.07.026","article-title":"Extracellular matrix composition is modified by \u03b2\u2082-agonists through cAMP in COPD","volume":"91","author":"Lambers","year":"2014","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0033","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1164\/ajrccm.156.6.9704112","article-title":"MMP and TIMP expression pattern in pleural effusions of different origin","volume":"156","author":"Eickelberg","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0034","doi-asserted-by":"crossref","first-page":"pii: E290","DOI":"10.3390\/nu9030290","article-title":"Methylsulfonylmethane: applications and safety of a novel dietary supplement","volume":"9","author":"Butawan","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0178925","article-title":"SUMO regulates p21Cip1 intracellular distribution and with p21Cip1 facilitates multiprotein complex formation in the nucleolus upon DNA damage","volume":"12","author":"Brun","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0036","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/jcb.27442","article-title":"Curcumin-mediated demethylation of the proximal promoter CpG island enhances the KLF4 recruitment that leads to increased expression of p21Cip1 in vitro","volume":"120","author":"Chatterjee","year":"2019","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0037","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.bbrc.2017.08.146","article-title":"Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma","volume":"493","author":"Nimpong","year":"2017","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0038","doi-asserted-by":"crossref","first-page":"26244","DOI":"10.1038\/srep26244","article-title":"Transcriptional repression of p27 is essential for murine embryonic development","volume":"6","author":"Teratake","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0039","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1183\/09059180.00004413","article-title":"Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype","volume":"23","author":"Pain","year":"2014","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0040","first-page":"1612","article-title":"Effects of bronchial thermoplasty on airway smooth muscle and collagen deposition in asthma","volume":"12","author":"Chakir","year":"2015","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0041","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/cea.12805","article-title":"Calpain-activated mTORC2\/Akt pathway mediates airway smooth muscle remodelling in asthma","volume":"47","author":"Rao","year":"2017","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0042","doi-asserted-by":"crossref","first-page":"pii: E875","DOI":"10.3390\/ijms20040875","article-title":"IgE downregulates PTEN through microRNA-21-5p and stimulates airway smooth muscle cell remodeling","volume":"20","author":"Fang","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0043","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4049\/jimmunol.1800782","article-title":"TGF-\u03b2 upregulated mitochondria mass through the SMAD2\/3\u2192C\/EBP\u03b2\u2192PRMT1 signal pathway in primary human lung fibroblasts","volume":"202","author":"Sun","year":"2019","journal-title":"J Immunol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0044","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1139\/cjpp-2014-0361","article-title":"Interaction between endoplasmic\/sarcoplasmic reticulum stress (ER\/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM)","volume":"93","author":"Delmotte","year":"2015","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0045","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.pharmthera.2016.06.019","article-title":"Mitochondria dysfunction: a novel therapeutic target in pathological lung remodeling or bystander?","volume":"166","author":"Rowlands","year":"2016","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0046","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1080\/10715762.2017.1414949","article-title":"Zinc prevents mitochondrial superoxide generation by inducing mitophagy in the setting of hypoxia\/reoxygenation in cardiac cells","volume":"52","author":"Bian","year":"2018","journal-title":"Free Radic Res"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0047","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.freeradbiomed.2017.03.032","article-title":"Zinc regulates Nox1 expression through a NF-\u03baB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells","volume":"108","author":"Salazar","year":"2017","journal-title":"Free Radic Biol Med"},{"issue":"6","key":"10.1016\/j.jnutbio.2020.108563_bib0048","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1165\/rcmb.2005-0196OC","article-title":"Eosinophil-mediated cholinergic nerve remodeling","volume":"34","author":"Durcan","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0049","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1074\/mcp.M112.017194","article-title":"Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation","volume":"11","author":"Fanis","year":"2012","journal-title":"Mol Cell Proteomics"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0050","doi-asserted-by":"crossref","first-page":"36112","DOI":"10.1074\/jbc.M703914200","article-title":"Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1\/phosphatidylinositol 3-kinase\/Akt2 feedback signaling","volume":"282","author":"Martin","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0051","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s11010-016-2837-4","article-title":"2-Deoxy glucose regulate MMP-9 in a SIRT-1 dependent and NFkB independent mechanism","volume":"423","author":"Edatt","year":"2016","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0052","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.3892\/mmr.2016.4935","article-title":"Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells","volume":"13","author":"Zheng","year":"2016","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0053","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1095\/biolreprod.102.006155","article-title":"Activating signal cointegrator 1 is highly expressed in murine testicular Leydig cells and enhances the ligand-dependent transactivation of androgen receptor","volume":"67","author":"Lee","year":"2002","journal-title":"Biol Reprod"},{"key":"10.1016\/j.jnutbio.2020.108563_bib0054","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1183\/09031936.00129610","article-title":"I\u03baB\u03b1 glutathionylation and reduced histone H3 phosphorylation inhibit eotaxin and RANTES","volume":"38","author":"Seidel","year":"2011","journal-title":"Eur Respir J"}],"updated-by":[{"DOI":"10.1016\/j.jnutbio.2021.108822","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000}}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286320305957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286320305957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T20:25:18Z","timestamp":1612815918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286320305957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":54,"alternative-id":["S0955286320305957"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2020.108563","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jnutbio.2021.108822","asserted-by":"object"}]},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zinc salicylate reduces airway smooth muscle cells remodelling by blocking mTOR and activating p21(Waf1\/Cip1)","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2020.108563","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"108563"}}