{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:13:45Z","timestamp":1791486825456,"version":"4.3.4"},"reference-count":132,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"am","delay-in-days":303,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["18TPA34230082"],"award-info":[{"award-number":["18TPA34230082"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.jnutbio.2022.108955","type":"journal-article","created":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T10:32:02Z","timestamp":1644057122000},"page":"108955","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Mechanisms of autophagic responses to altered nutritional status"],"prefix":"10.1016","volume":"103","author":[{"given":"Zhipeng","family":"Tao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiba","family":"Aslam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Parke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7615-9788","authenticated-orcid":false,"given":"Zhiyong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2022.108955_bib0001","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.cmet.2011.04.004","article-title":"Autophagy in the cellular energetic balance","volume":"13","author":"Singh","year":"2011","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0002","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0003","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.tem.2019.07.009","article-title":"The FoxO\u2013autophagy Axis in health and disease","volume":"30","author":"Cheng","year":"2019","journal-title":"Trends in Endocrinol & Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0004","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cell.2018.09.048","article-title":"Biological functions of autophagy genes: a disease perspective","volume":"176","author":"Levine","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0005","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1056\/NEJMra2022774","article-title":"Autophagy in Human Diseases","volume":"383","author":"Mizushima","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0006","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/nrm3249","article-title":"Proikas-Cezanne T. Canonical and non-canonical autophagy: variations on a common theme of self-eating?","volume":"13","author":"Codogno","year":"2012","journal-title":"Nature Rev Molecular cell biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0007","doi-asserted-by":"crossref","first-page":"e00389","DOI":"10.1128\/MCB.00389-20","article-title":"Canonical and non-canonical autophagy pathways in microglia","volume":"41","author":"Julg","year":"2021","journal-title":"Molecular and cellular biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0008","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1089\/ars.2010.3482","article-title":"Autophagosome formation and molecular mechanism of autophagy","volume":"14","author":"Tanida","year":"2011","journal-title":"Antioxidants & redox signaling"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0009","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2337\/db17-0223","article-title":"S-Nitrosoglutathione reductase dysfunction contributes to obesity-associated hepatic insulin resistance via regulating autophagy","volume":"67","author":"Qian","year":"2018","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0010","doi-asserted-by":"crossref","first-page":"890","DOI":"10.4161\/cc.28189","article-title":"Mitochondrial alteration in type 2 diabetes and obesity: an epigenetic link","volume":"13","author":"Cheng","year":"2014","journal-title":"Cell cycle"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0011","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/ejcn.2016.231","article-title":"From the past to future: from energy expenditure to energy intake to energy expenditure","volume":"71","author":"M\u00fcller","year":"2017","journal-title":"Eur J Clin Nutrition"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/cddiscovery.2016.66","article-title":"FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes","volume":"2","author":"Liu","year":"2016","journal-title":"Cell death discovery"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0013","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s13679-018-0308-9","article-title":"Intermittent fasting: is the wait worth the weight?","volume":"7","author":"Stockman","year":"2018","journal-title":"Curr Obes Rep"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0014","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1017\/S0029665119000636","article-title":"The role of intermittent fasting and meal timing in weight management and metabolic health","volume":"79","author":"Templeman","year":"2020","journal-title":"Proc Nutr Soc"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0015","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.cell.2014.11.006","article-title":"Metabolic control of autophagy","volume":"159","author":"Galluzzi","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0016","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1038\/s41598-017-02088-2","article-title":"Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling","volume":"7","author":"Pettersen","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0017","doi-asserted-by":"crossref","first-page":"2674","DOI":"10.1016\/j.jmb.2019.05.032","article-title":"Autophagy exacerbates muscle wasting in cancer cachexia and impairs mitochondrial function","volume":"431","author":"Penna","year":"2019","journal-title":"J Mol Biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0018","first-page":"241","article-title":"Coming back: autophagy in cachexia","volume":"17","author":"Penna","year":"2014","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0019","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.cmet.2010.04.005","article-title":"Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance","volume":"11","author":"Yang","year":"2010","journal-title":"Cell Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0020","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1007\/s10620-015-4025-x","article-title":"Function of autophagy in nonalcoholic fatty liver disease","volume":"61","author":"Czaja","year":"2016","journal-title":"Digestive Dis and Sci"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0021","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/embor.2012.115","article-title":"The neurobiology of overeating: treating overweight individuals should make use of neuroscience research, but not at the expense of population approaches to diet and lifestyle","volume":"13","author":"Lee","year":"2012","journal-title":"EMBO reports"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0022","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1093\/jn\/nxy062","article-title":"Food overconsumption in healthy adults triggers early and sustained increases in serum branched-chain amino acids and changes in cysteine linked to fat gain","volume":"148","author":"Elshorbagy","year":"2018","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0023","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/oby.22456","article-title":"Metabolic determinants of weight gain in humans","volume":"27","author":"Piaggi","year":"2019","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0024","first-page":"3","article-title":"Autophagy dysregulation and obesity-associated pathologies","volume":"41","author":"Namkoong","year":"2018","journal-title":"Molecules and cells"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0025","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1152\/physiol.00048.2015","article-title":"Transcriptional dysregulation of adipose tissue autophagy in obesity","volume":"31","author":"Maixner","year":"2016","journal-title":"Physiology"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0026","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1080\/15548627.2015.1094597","article-title":"Elevated autophagy gene expression in adipose tissue of obese humans: a potential non-cell-cycle-dependent function of E2F1","volume":"11","author":"Haim","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0027","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.mce.2015.03.015","article-title":"Autophagy in adipose tissue of patients with obesity and type 2 diabetes","volume":"409","author":"Kosacka","year":"2015","journal-title":"Molecular and cellular endocrinology"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0028","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1038\/ijo.2016.5","article-title":"Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity","volume":"40","author":"Slutsky","year":"2016","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0029","doi-asserted-by":"crossref","first-page":"E268","DOI":"10.1210\/jc.2010-1681","article-title":"Altered autophagy in human adipose tissues in obesity","volume":"96","author":"Kovsan","year":"2011","journal-title":"The J Clin Endocrinol and Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/21623945.2017.1394537","article-title":"Adipose tissue autophagy related gene expression is associated with glucometabolic status in human obesity","volume":"7","author":"Xu","year":"2018","journal-title":"Adipocyte"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0031","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.2337\/db14-1933","article-title":"DAPK2 downregulation associates with attenuated adipocyte autophagic clearance in human obesity","volume":"64","author":"Soussi","year":"2015","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0032","doi-asserted-by":"crossref","first-page":"E262","DOI":"10.1152\/ajpendo.00271.2013","article-title":"Metabolic remodeling of white adipose tissue in obesity","volume":"307","author":"Cummins","year":"2014","journal-title":"Am J Physiol-Endocrinol and Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0033","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1080\/15548627.2016.1274850","article-title":"Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice","volume":"13","author":"Mizunoe","year":"2017","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0034","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1016\/j.celrep.2018.10.040","article-title":"Autophagy ablation in adipocytes induces insulin resistance and reveals roles for lipid peroxide and Nrf2 signaling in adipose-liver crosstalk","volume":"25","author":"Cai","year":"2018","journal-title":"Cell reports"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0035","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1080\/15548627.2019.1703355","article-title":"Sustained activation of autophagy suppresses adipocyte maturation via a lipolysis-dependent mechanism","volume":"16","author":"Zhang","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0036","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/ncb2718","article-title":"TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop","volume":"15","author":"Settembre","year":"2013","journal-title":"Nature cell biology"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0037","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nature13949","article-title":"Transcriptional regulation of autophagy by an FXR\u2013CREB axis","volume":"516","author":"Seok","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0038","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nature13961","article-title":"Nutrient-sensing nuclear receptors coordinate autophagy","volume":"516","author":"Lee","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0039","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.15252\/embj.201695500","article-title":"A postprandial FGF 19-SHP-LSD 1 regulatory axis mediates epigenetic repression of hepatic autophagy","volume":"36","author":"Byun","year":"2017","journal-title":"The EMBO journal"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0040","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1194\/jlr.RA119000336","article-title":"Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting","volume":"61","author":"Zhang","year":"2020","journal-title":"Journal of lipid research"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-020-14384-z","article-title":"Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase","volume":"11","author":"Byun","year":"2020","journal-title":"Nature communications"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0042","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/cr.2017.45","article-title":"Fasting-induced hormonal regulation of lysosomal function","volume":"27","author":"Chen","year":"2017","journal-title":"Cell research"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0043","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.cmet.2019.01.018","article-title":"Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential","volume":"29","author":"Madeo","year":"2019","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0044","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.3390\/nu11061234","article-title":"Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans","volume":"11","author":"Jamshed","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0045","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.cmet.2017.09.020","article-title":"System-wide benefits of intermeal fasting by autophagy","volume":"26","author":"Martinez-Lopez","year":"2017","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0046","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1080\/15548627.2015.1063768","article-title":"Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury","volume":"11","author":"Godar","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0047","doi-asserted-by":"crossref","first-page":"H219","DOI":"10.1152\/ajpheart.00041.2016","article-title":"Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance","volume":"311","author":"Andres","year":"2016","journal-title":"Am J Physiol-Heart and Circulatory Physiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0048","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.cmet.2015.05.016","article-title":"AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging","volume":"21","author":"Bujak","year":"2015","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0049","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40478-018-0518-0","article-title":"Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease","volume":"6","author":"Ehrnhoefer","year":"2018","journal-title":"Acta Neuropathologica Commun"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0050","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.cmet.2015.10.008","article-title":"Autophagy in the CNS and periphery coordinate lipophagy and lipolysis in the brown adipose tissue and liver","volume":"23","author":"Martinez-Lopez","year":"2016","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0051","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-018-1044-5","article-title":"Rapamycin and fasting sustain autophagy response activated by ischemia\/reperfusion injury and promote retinal ganglion cell survival","volume":"9","author":"Russo","year":"2018","journal-title":"Cell death & dis"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0052","doi-asserted-by":"crossref","first-page":"e12876","DOI":"10.1111\/acel.12876","article-title":"Autophagy and aging: Maintaining the proteome through exercise and caloric restriction","volume":"18","author":"Escobar","year":"2019","journal-title":"Aging cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0053","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.cell.2011.07.030","article-title":"Autophagy and aging","volume":"146","author":"Rubinsztein","year":"2011","journal-title":"Cell."},{"key":"10.1016\/j.jnutbio.2022.108955_bib0054","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3390\/nu11040719","article-title":"The influence of meal frequency and timing on health in humans: the role of fasting","volume":"11","author":"Paoli","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0055","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1113\/JP277091","article-title":"Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy","volume":"597","author":"Lu","year":"2019","journal-title":"The J physiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0056","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1080\/15548627.2017.1368596","article-title":"Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway","volume":"13","author":"Liu","year":"2017","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0057","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1152\/physiol.00010.2011","article-title":"Calorie restriction: is AMPK a key sensor and effector?","volume":"26","author":"Cant\u00f3","year":"2011","journal-title":"Physiology"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0058","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.cmet.2017.10.009","article-title":"AMPK: sensing glucose as well as cellular energy status","volume":"27","author":"Lin","year":"2018","journal-title":"Cell Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0059","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/ncb2152","article-title":"AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1","volume":"13","author":"Kim","year":"2011","journal-title":"Nature cell biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-017-00520-9","article-title":"Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy","volume":"8","author":"Laker","year":"2017","journal-title":"Nature Commun"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0061","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/s41556-018-0176-2","article-title":"Mechanisms of mitophagy in cellular homeostasis, physiology and pathology","volume":"20","author":"Palikaras","year":"2018","journal-title":"Nature cell biology"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0062","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1152\/japplphysiol.01146.2017","article-title":"Training state and skeletal muscle autophagy in response to 36 h of fasting","volume":"125","author":"Dethlefsen","year":"2018","journal-title":"J Applied Physiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0063","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.molcel.2018.09.017","article-title":"mTORC1-regulated and HUWE1-mediated WIPI2 degradation controls autophagy flux","volume":"72","author":"Wan","year":"2018","journal-title":"Molecular cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0064","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1126\/science.1099196","article-title":"Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase","volume":"305","author":"Cohen","year":"2004","journal-title":"science"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms12723","article-title":"Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1\u03b1\/SIRT1-dependent transcriptional regulation of mitochondrial function","volume":"7","author":"Gallardo-Montejano","year":"2016","journal-title":"Nature commun"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0066","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1073\/pnas.0712145105","article-title":"A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy","volume":"105","author":"Lee","year":"2008","journal-title":"Proceedings of the National Acad Sci"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0067","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1161\/CIRCRESAHA.110.227371","article-title":"Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes","volume":"107","author":"Hariharan","year":"2010","journal-title":"Circulation res"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0068","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.molcel.2014.12.013","article-title":"Deacetylation of nuclear LC3 drives autophagy initiation under starvation","volume":"57","author":"Huang","year":"2015","journal-title":"Molecular cell"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0069","doi-asserted-by":"crossref","first-page":"5654","DOI":"10.1007\/s12035-019-1483-8","article-title":"The role of Beclin-1 acetylation on autophagic flux in alzheimer's disease","volume":"56","author":"Esteves","year":"2019","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0070","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1242\/dev.147074","article-title":"Sirt1 regulates acrosome biogenesis by modulating autophagic flux during spermiogenesis in mice","volume":"144","author":"Liu","year":"2017","journal-title":"Development"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0071","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41420-021-00438-8","article-title":"Sirt1 coordinates with ERalpha to regulate autophagy and adiposity","volume":"7","author":"Tao","year":"2021","journal-title":"Cell death discovery"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0072","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev-physiol-021115-105339","article-title":"Understanding the physiology of FGF21","volume":"78","author":"Fisher","year":"2016","journal-title":"Annual rev of physiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0073","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.yexcr.2017.05.006","article-title":"Fatty liver and FGF21 physiology","volume":"360","author":"Maratos-Flier","year":"2017","journal-title":"Experimental cell res"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0074","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.cmet.2019.01.004","article-title":"A dozen years of discovery: insights into the physiology and pharmacology of FGF21","volume":"29","author":"Kliewer","year":"2019","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0075","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1146\/annurev.biochem.73.071403.161303","article-title":"Inositol 1, 4, 5-trisphosphate receptors as signal integrators","volume":"73","author":"Patterson","year":"2004","journal-title":"Annual rev biochem"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0076","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.tibs.2005.10.005","article-title":"Phospholipase C-\u03b3: diverse roles in receptor-mediated calcium signaling","volume":"30","author":"Patterson","year":"2005","journal-title":"Trends in biochem sci"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0077","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1146\/annurev.biochem.70.1.281","article-title":"Regulation of phosphoinositide-specific phospholipase C","volume":"70","author":"Rhee","year":"2001","journal-title":"Annual rev biochem"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0078","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cmet.2012.11.001","article-title":"Circulating fibroblast growth factors as metabolic regulators\u2014a critical appraisal","volume":"16","author":"Angelin","year":"2012","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0079","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.tem.2014.10.002","article-title":"Tissue-specific actions of the metabolic hormones FGF15\/19 and FGF21","volume":"26","author":"Owen","year":"2015","journal-title":"Trends in Endocrinol & Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0080","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.cmet.2007.05.003","article-title":"Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21","volume":"5","author":"Inagaki","year":"2007","journal-title":"Cell Metab"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0081","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.cmet.2007.05.002","article-title":"Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states","volume":"5","author":"Badman","year":"2007","journal-title":"Cell Metab"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0082","first-page":"10","article-title":"Relevance of Autophagy Induction by Gastrointestinal Hormones: Focus on the Incretin-Based Drug Target and Glucagon","author":"Kanasaki","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0083","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/nrgastro.2016.185","article-title":"Autophagy in the liver: functions in health and disease","volume":"14","author":"Ueno","year":"2017","journal-title":"Nat Rev Gastro Hepat"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0084","series-title":"Autophagy in health and disease- potential therapeutic approaches","first-page":"47","article-title":"Forkhead box O (FoxO) transcription factors in autophagy, metabolic Health, and tissue Homeostasis","author":"Liu","year":"2018"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0085","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1253\/circj.CJ-14-1080","article-title":"Insulin regulation of myocardial autophagy","volume":"78","author":"Riehle","year":"2014","journal-title":"Circ J"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0086","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1038\/s41467-018-04697-5","article-title":"Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis","volume":"9","author":"Byun","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0087","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cmet.2005.09.001","article-title":"Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis","volume":"2","author":"Inagaki","year":"2005","journal-title":"Cell metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0088","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1126\/science.1198363","article-title":"FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis","volume":"331","author":"Kir","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0089","doi-asserted-by":"crossref","first-page":"19860","DOI":"10.1073\/pnas.0906048106","article-title":"Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis","volume":"106","author":"Zhang","year":"2009","journal-title":"Proceedings of the National Acad Sci"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0090","first-page":"3329","article-title":"Autophagy regulates adipose mass and differentiation in mice","volume":"119","author":"Singh","year":"2009","journal-title":"The J clin investigation"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0091","doi-asserted-by":"crossref","first-page":"E1030","DOI":"10.1152\/ajpendo.00386.2014","article-title":"Effects of weight gain induced by controlled overfeeding on physical activity","volume":"307","author":"Apolzan","year":"2014","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0092","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1038\/ijosup.2012.23","article-title":"Clinical effects of high-fat meals and weight gain due to high-fat feeding","volume":"2","author":"Gupta","year":"2012","journal-title":"Int J Obes Suppl"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0093","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1001\/jama.2011.1918","article-title":"Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial","volume":"307","author":"Bray","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0094","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1002\/ame2.12084","article-title":"Characterization of inflammation and insulin resistance in high-fat diet-induced male C57BL\/6J mouse model of obesity","volume":"2","author":"Avtanski","year":"2019","journal-title":"Animal Model Exp Med"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0095","doi-asserted-by":"crossref","first-page":"32484","DOI":"10.1038\/srep32484","article-title":"High fat diet drives obesity regardless the composition of gut microbiota in mice","volume":"6","author":"Rabot","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0096","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/978-1-61779-430-8_27","article-title":"A mouse model of diet-induced obesity and insulin resistance","volume":"821","author":"Wang","year":"2012","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0097","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.3945\/jn.117.257873","article-title":"Long-term intake of a high-protein diet affects body phenotype, metabolism, and plasma hormones in mice","volume":"147","author":"Vu","year":"2017","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0098","doi-asserted-by":"crossref","first-page":"E886","DOI":"10.1152\/ajpendo.00363.2015","article-title":"Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice","volume":"310","author":"Kiilerich","year":"2016","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0099","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/s41366-018-0030-4","article-title":"ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: Role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1\u03b1 deacetylation","volume":"42","author":"Wang","year":"2018","journal-title":"Int J obesity"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0100","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/humrep\/dew048","article-title":"Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy","volume":"31","author":"Rhee","year":"2016","journal-title":"Human Reproduction"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0101","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1194\/jlr.M055152","article-title":"Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity","volume":"56","author":"Jaishy","year":"2015","journal-title":"J lipid res"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0102","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2119\/molmed.2010.00023","article-title":"Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes","volume":"16","author":"\u00d6st","year":"2010","journal-title":"Molecular med"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0103","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.tem.2010.06.005","article-title":"Insulin signaling meets mitochondria in metabolism","volume":"21","author":"Cheng","year":"2010","journal-title":"Trends in Endocrinol & Metabolism"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-019-1393-8","article-title":"Obesity-associated inflammation triggers an autophagy\u2013lysosomal response in adipocytes and causes degradation of perilipin 1","volume":"10","author":"Ju","year":"2019","journal-title":"Cell death & dis"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0105","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jnutbio.2019.03.014","article-title":"High fructose diet induces early mortality via autophagy factors accumulation in the rostral ventrolateral medulla as ameliorated by pioglitazone","volume":"69","author":"Lin","year":"2019","journal-title":"The J nutritional biochem"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0106","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00394-015-1086-8","article-title":"Effects of chronic sugar consumption on lipid accumulation and autophagy in the skeletal muscle","volume":"56","author":"De Stefanis","year":"2017","journal-title":"Eur J nutrition"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0107","doi-asserted-by":"crossref","first-page":"E597","DOI":"10.1152\/ajpendo.00022.2012","article-title":"Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation","volume":"303","author":"Gornicka","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0108","first-page":"1","article-title":"Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes","volume":"10","author":"Mizunoe","year":"2020","journal-title":"Scientific rep"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0109","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.113885","article-title":"Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma","volume":"176","author":"Rizza","year":"2020","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0110","doi-asserted-by":"crossref","first-page":"E3388","DOI":"10.1073\/pnas.1722452115","article-title":"S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy","volume":"115","author":"Rizza","year":"2018","journal-title":"Proceedings of the National Acad Sci USA"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0111","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1089\/ars.2015.6548","article-title":"GSNOR Deficiency Enhances In Situ Skeletal Muscle Strength, Fatigue Resistance, and RyR1 S-Nitrosylation Without Impacting Mitochondrial Content and Activity","volume":"26","author":"Moon","year":"2017","journal-title":"Antioxidants & redox signaling"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0112","doi-asserted-by":"crossref","first-page":"E2950","DOI":"10.1073\/pnas.1307736110","article-title":"Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1","volume":"110","author":"Tripathi","year":"2013","journal-title":"Proceedings of the National Acad Sci USA"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0113","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1089\/ars.2009.3074","article-title":"Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders","volume":"13","author":"Calabrese","year":"2010","journal-title":"Antioxidants & redox signaling"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0114","article-title":"Autophagy, and Hormesis in cell physiology, pathology, and age-related disease","volume":"18","author":"Lysosomes","year":"2020","journal-title":"Dose Response"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0115","doi-asserted-by":"crossref","first-page":"903","DOI":"10.4161\/auto.19653","article-title":"MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB","volume":"8","author":"Martina","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0116","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1080\/15548627.2018.1490850","article-title":"Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply","volume":"14","author":"Zhang","year":"2018","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0117","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/7651_2017_65","article-title":"Autophagy in adipocyte differentiation","volume":"1854","author":"Tao","year":"2019","journal-title":"Methods in molecular biol (Clifton, NJ)"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0118","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.tibs.2020.07.006","article-title":"Autophagy assays for biological discovery and therapeutic development","volume":"45","author":"Mizushima","year":"2020","journal-title":"Trends in Biochemical Sci"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0119","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2020.1797280","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy","volume":"17","author":"Klionsky","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0120","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1681\/ASN.2016070731","article-title":"High-fat diet-induced lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in the kidney","volume":"28","author":"Yamamoto","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0121","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.33549\/physiolres.932394","article-title":"Effect of short-and long-term high-fat feeding on autophagy flux and lysosomal activity in rat liver","volume":"61","author":"Papackova","year":"2012","journal-title":"Physiol res"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0122","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1161\/CIRCRESAHA.119.314967","article-title":"Activation of mitophagy in high-fat diet\u2013induced diabetic cardiomyopathy","volume":"124","author":"Rabinovich-Nikitin","year":"2019","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0123","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1161\/CIRCRESAHA.118.314607","article-title":"Mitophagy is essential for maintaining cardiac function during high fat diet-induced diabetic cardiomyopathy","volume":"124","author":"Tong","year":"2019","journal-title":"Circulation research"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0124","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ebiom.2018.03.028","article-title":"Trans-fats inhibit autophagy induced by saturated fatty acids","volume":"30","author":"Sauvat","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-48973-w","article-title":"High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver","volume":"9","author":"Naito","year":"2019","journal-title":"Scientific reports"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0126","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/cdd.2010.191","article-title":"The Beclin 1 network regulates autophagy and apoptosis","volume":"18","author":"Kang","year":"2011","journal-title":"Cell death and differentiation"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0127","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1007\/s12035-015-9453-2","article-title":"Beclin-1 deficiency alters autophagosome formation, lysosome biogenesis and enhances neuronal vulnerability of HT22 hippocampal cells","volume":"53","author":"Fekadu","year":"2016","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0128","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1128\/MCB.01091-14","article-title":"Regulation of the transcription factor EB-PGC1alpha axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress","volume":"35","author":"Ma","year":"2015","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0129","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.freeradbiomed.2018.12.039","article-title":"The roles of oxidative stress and Beclin-1 in the autophagosome clearance impairment triggered by cardiac arrest","volume":"136","author":"Wang","year":"2019","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0130","doi-asserted-by":"crossref","first-page":"R82","DOI":"10.1186\/gb-2013-14-7-r82","article-title":"A comparative phenotypic and genomic analysis of C57BL\/6J and C57BL\/6N mouse strains","volume":"14","author":"Simon","year":"2013","journal-title":"Genome Biol"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0131","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/15548627.2018.1520549","article-title":"How does estrogen work on autophagy?","volume":"15","author":"Xiang","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2022.108955_bib0132","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/s41419-018-0372-9","article-title":"Estradiol signaling mediates gender difference in visceral adiposity via autophagy","volume":"9","author":"Tao","year":"2018","journal-title":"Cell death & dis"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286322000262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286322000262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:34:19Z","timestamp":1760628859000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286322000262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":132,"alternative-id":["S0955286322000262"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2022.108955","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanisms of autophagic responses to altered nutritional status","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2022.108955","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108955"}}