{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T18:56:26Z","timestamp":1788980186640,"version":"build-2803163510"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007469","name":"Higher Education Research Promotion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007469","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["715662"],"award-info":[{"award-number":["715662"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004071","name":"Khon Kaen University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004396","name":"Thailand Research Fund","doi-asserted-by":"publisher","award":["PHD\/0037\/2558"],"award-info":[{"award-number":["PHD\/0037\/2558"]}],"id":[{"id":"10.13039\/501100004396","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012527","name":"Office of the Higher Education Commission","doi-asserted-by":"publisher","award":["NRU592004"],"award-info":[{"award-number":["NRU592004"]}],"id":[{"id":"10.13039\/100012527","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012527","name":"Office of the Higher Education Commission","doi-asserted-by":"publisher","award":["RP65-2-001"],"award-info":[{"award-number":["RP65-2-001"]}],"id":[{"id":"10.13039\/100012527","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/P002536\/1"],"award-info":[{"award-number":["MR\/P002536\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.jnutbio.2022.109053","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T18:29:08Z","timestamp":1653503348000},"page":"109053","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Opisthorchis viverrini infection induces metabolic disturbances in hamsters fed with high fat\/high fructose diets: Implications for liver and kidney pathologies"],"prefix":"10.1016","volume":"107","author":[{"given":"Ornuma","family":"Haonon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1363-6708","authenticated-orcid":false,"given":"Zhigang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rungtiwa","family":"Dangtakot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Porntip","family":"Pinlaor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anucha","family":"Puapairoj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ubon","family":"Cha'on","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitti","family":"Intuyod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thatsanapong","family":"Pongking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanakan","family":"Jantawong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chatchawan","family":"Sengthong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6495-0951","authenticated-orcid":false,"given":"Apisit","family":"Chaidee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudarat","family":"Onsurathum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia V.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somchai","family":"Pinlaor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2022.109053_bib0001","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.parint.2011.08.014","article-title":"The current status of opisthorchiasis and clonorchiasis in the Mekong Basin","volume":"61","author":"Sithithaworn","year":"2012","journal-title":"Parasitol Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0002","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1093\/ndt\/gfp669","article-title":"Prevalence and risk factors of chronic kidney disease in the Thai adult population: Thai SEEK study","volume":"25","author":"Ingsathit","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0003","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1056\/NEJMoa1214234","article-title":"Cystatin C versus creatinine in determining risk based on kidney function","volume":"369","author":"Shlipak","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0004","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.pt.2012.07.006","article-title":"The tumorigenic liver fluke Opisthorchis viverrini\u2013multiple pathways to cancer","volume":"28","author":"Sripa","year":"2012","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0005","doi-asserted-by":"crossref","first-page":"e201","DOI":"10.1371\/journal.pmed.0040201","article-title":"Liver fluke induces cholangiocarcinoma","volume":"4","author":"Sripa","year":"2007","journal-title":"PLoS Med"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0006","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.parint.2011.07.009","article-title":"Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand","volume":"61","author":"Mairiang","year":"2012","journal-title":"Parasitol Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0007","doi-asserted-by":"crossref","first-page":"e2228","DOI":"10.1371\/journal.pntd.0002228","article-title":"Microproteinuria during Opisthorchis viverrini infection: a biomarker for advanced renal and hepatobiliary pathologies from chronic opisthorchiasis","volume":"7","author":"Saichua","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0008","first-page":"67","article-title":"Opisthorchiasis-related nephropathy","author":"Lapteva","year":"1990","journal-title":"Vrach Delo"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0009","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1001\/archinte.1990.00390220095019","article-title":"Acute renal failure in obstructive jaundice in cholangiocarcinoma","volume":"150","author":"Mairiang","year":"1990","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0010","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1016\/j.jhep.2014.12.012","article-title":"NAFLD: a multisystem disease","volume":"62","author":"Byrne","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0011","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.12688\/f1000research.12417.1","article-title":"Gender differences in the prevalence of nonalcoholic fatty liver disease in the Northeast of Thailand: a population-based cross-sectional study","volume":"6","author":"Summart","year":"2017","journal-title":"F1000Res."},{"key":"10.1016\/j.jnutbio.2022.109053_bib0012","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.4254\/wjh.v7.i13.1788","article-title":"Non-alcohol fatty liver disease in Asia: Prevention and planning","volume":"7","author":"Ashtari","year":"2015","journal-title":"World J Hepatol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0013","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0140-6736(11)60178-5","article-title":"Chronic kidney disease","volume":"379","author":"Levey","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0014","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1097\/01.ASN.0000070147.10399.9E","article-title":"Risk factors for progressive chronic kidney disease","volume":"14","author":"McClellan","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0015","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.2337\/dc15-1182","article-title":"Fatty liver and chronic kidney disease: novel mechanistic insights and therapeutic opportunities","volume":"39","author":"Musso","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0016","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/hep.26717","article-title":"Extrahepatic complications of nonalcoholic fatty liver disease","volume":"59","author":"Armstrong","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0017","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1053\/j.ajkd.2014.05.019","article-title":"CKD and nonalcoholic fatty liver disease","volume":"64","author":"Targher","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0018","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1002\/hep.28356","article-title":"The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota","volume":"63","author":"Boursier","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0019","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.4269\/ajtmh.19-0442","article-title":"Opisthorchis viverrini infection augments the severity of nonalcoholic fatty liver disease in high-fat\/high-fructose diet-fed hamsters","volume":"101","author":"Chaidee","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0020","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/1476-511X-12-136","article-title":"Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats","volume":"12","author":"de Castro","year":"2013","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0021","doi-asserted-by":"crossref","first-page":"F1256","DOI":"10.1152\/ajprenal.00181.2007","article-title":"Fructose, but not dextrose, accelerates the progression of chronic kidney disease","volume":"293","author":"Gersch","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"issue":"Suppl 1","key":"10.1016\/j.jnutbio.2022.109053_bib0022","first-page":"7","article-title":"Development of immune-complex glomerulonephritis and amyloidosis in Syrian golden hamsters infected with Opisthorchis viverrini","volume":"75","author":"Boonpucknavig","year":"1992","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0023","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.tim.2011.05.006","article-title":"Understanding the role of gut microbiome-host metabolic signal disruption in health and disease","volume":"19","author":"Holmes","year":"2011","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0024","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/gm228","article-title":"Gut microbiome-host interactions in health and disease","volume":"3","author":"Kinross","year":"2011","journal-title":"Genome Med"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0025","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/978-3-319-47656-8_10","article-title":"Chronic diseases and lifestyle biomarkers identification by metabolomics","volume":"965","author":"Mastrangelo","year":"2017","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0026","doi-asserted-by":"crossref","first-page":"12676","DOI":"10.1073\/pnas.0404878101","article-title":"Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification","volume":"101","author":"Wang","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0027","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ijpara.2008.10.010","article-title":"Metabolic profiling of a Schistosoma mansoni infection in mouse tissues using magic angle spinning-nuclear magnetic resonance spectroscopy","volume":"39","author":"Li","year":"2009","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0028","doi-asserted-by":"crossref","first-page":"e807","DOI":"10.1371\/journal.pntd.0000807","article-title":"Metabolic changes reveal the development of schistosomiasis in mice","volume":"4","author":"Wu","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0029","doi-asserted-by":"crossref","first-page":"5442","DOI":"10.1021\/pr900711j","article-title":"Systems metabolic effects of a Necator americanus infection in Syrian hamster","volume":"8","author":"Wang","year":"2009","journal-title":"J Proteome Res"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008015","article-title":"Plasma metabolomics of the time resolved response to Opisthorchis felineus infection in an animal model (golden hamster, Mesocricetus auratus)","volume":"14","author":"Kokova","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0031","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006044","article-title":"Exploratory metabolomics study of the experimental opisthorchiasis in a laboratory animal model (golden hamster, Mesocricetus auratus)","volume":"11","author":"Kokova","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0032","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1136\/gutjnl-2011-301012","article-title":"Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota","volume":"61","author":"Serino","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0033","doi-asserted-by":"crossref","first-page":"e12390","DOI":"10.1111\/pim.12390","article-title":"Prazeres da Costa C. Parasites, microbiota and metabolic disease","volume":"39","author":"Bhattacharjee","year":"2017","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0034","doi-asserted-by":"crossref","first-page":"15651","DOI":"10.1038\/s41598-018-33937-3","article-title":"A comprehensive analysis of the faecal microbiome and metabolome of Strongyloides stercoralis infected volunteers from a non-endemic area","volume":"8","author":"Jenkins","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0035","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1096\/fj.13-232751","article-title":"Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome","volume":"27","author":"Plieskatt","year":"2013","journal-title":"FASEB J"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165798","article-title":"Chronic Opisthorchis viverrini infection changes the liver microbiome and promotes helicobacter growth","volume":"11","author":"Itthitaetrakool","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0037","doi-asserted-by":"crossref","first-page":"e00642","DOI":"10.1128\/IAI.00642-19","article-title":"Whipworm infection promotes bacterial invasion, intestinal microbiota imbalance, and cellular immunomodulation","volume":"88","author":"Schachter","year":"2020","journal-title":"Infect Immun"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0038","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1017\/S0031182014000699","article-title":"The microbiota and helminths: sharing the same niche in the human host","volume":"141","author":"Glendinning","year":"2014","journal-title":"Parasitology"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0039","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3389\/fendo.2019.00611","article-title":"Gut dysfunction and non-alcoholic fatty liver disease","volume":"10","author":"Grabherr","year":"2019","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0040","doi-asserted-by":"crossref","first-page":"5214","DOI":"10.3390\/ijms21155214","article-title":"Gut microbiota metabolites in NAFLD pathogenesis and therapeutic implications","volume":"21","author":"Chen","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0041","doi-asserted-by":"crossref","first-page":"3940","DOI":"10.1021\/acs.jproteome.1c00246","article-title":"Opisthorchis viverrini Infection induces metabolic and fecal microbial disturbances in association with liver and kidney pathologies in hamsters","volume":"20","author":"Haonon","year":"2021","journal-title":"J Proteome Res"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0042","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.apar.2018.07.001","article-title":"Opisthorchiasis and the microbiome","volume":"102","author":"Saltykova","year":"2018","journal-title":"Adv Parasitol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0043","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.4269\/ajtmh.19-0442","article-title":"Opisthorchis viverrini infection augments the severity of nonalcoholic fatty liver disease in high-fat\/high-fructose diet-fed hamsters","author":"Chaidee","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0044","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1440-1797.2007.00855.x","article-title":"Quantification of renal pathology by image analysis","volume":"12","author":"Rangan","year":"2007","journal-title":"Nephrology"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0045","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/sj.ki.5002697","article-title":"Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury","volume":"73","author":"Zhang","year":"2008","journal-title":"Kidney Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0046","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1021\/ac051632c","article-title":"Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomics","volume":"78","author":"Dieterle","year":"2006","journal-title":"Anal Chem"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0047","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1021\/ac8011544","article-title":"Recursive segment-wise peak alignment of biological 1H NMR spectra for improved metabolic biomarker recovery","volume":"81","author":"Veselkov","year":"2009","journal-title":"Anal Chem"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0048","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1021\/acs.jproteome.6b00179","article-title":"Quantitative metabolomic profiling of plasma, urine, and liver extracts by 1h nmr spectroscopy characterizes different stages of atherosclerosis in hamsters","volume":"15","author":"Guo","year":"2016","journal-title":"J Proteome Res"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0049","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.ijpara.2009.11.003","article-title":"Metabolic alterations in the hamster co-infected with Schistosoma japonicum and Necator americanus","volume":"40","author":"Wu","year":"2010","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0231237","article-title":"A combination of monosodium glutamate and high-fat and high-fructose diets increases the risk of kidney injury, gut dysbiosis and host-microbial co-metabolism","volume":"15","author":"Pongking","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0051","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nrgastro.2013.149","article-title":"Feldstein AE. From NAFLD to NASH to cirrhosis-new insights into disease mechanisms","volume":"10","author":"Wree","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0052","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1462-8902.2004.00323.x","article-title":"The effect of high-fat and high-fructose diets on glucose tolerance and plasma lipid and leptin levels in rats","volume":"6","author":"Huang","year":"2004","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0053","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.2147\/DMSO.S211253","article-title":"High-fat diet-induced kidney alterations in rats with metabolic syndrome: endothelial dysfunction and decreased antioxidant defense","volume":"12","author":"Rangel Silvares","year":"2019","journal-title":"Diabetes Metab Syndr Obes"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0054","doi-asserted-by":"crossref","first-page":"E1047","DOI":"10.1152\/ajpendo.00666.2010","article-title":"High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production","volume":"300","author":"Ruggiero","year":"2011","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0055","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1046\/j.1523-1755.2002.00433.x","article-title":"Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury","volume":"62","author":"Han","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0056","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1093\/ndt\/17.12.2043","article-title":"Monocyte chemoattractant protein-1 (MCP-1) in the kidney: does it more than simply attract monocytes?","volume":"17","author":"Viedt","year":"2002","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0057","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/imr.12601","article-title":"High-mobility group box 1 protein orchestrates responses to tissue damage via inflammation, innate and adaptive immunity, and tissue repair","volume":"280","author":"Bianchi","year":"2017","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0058","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.apsb.2016.02.004","article-title":"The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases","volume":"6","author":"Chen","year":"2016","journal-title":"Acta Pharm Sin B"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0059","doi-asserted-by":"crossref","first-page":"520","DOI":"10.3389\/fphar.2017.00520","article-title":"Progression of tubulointerstitial fibrosis and the chronic kidney disease phenotype - role of risk factors and epigenetics","volume":"8","author":"Hewitson","year":"2017","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0060","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jcmgh.2019.04.007","article-title":"Metabolic targets in nonalcoholic fatty liver disease","volume":"8","author":"Esler","year":"2019","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0061","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1093\/ckj\/sfy037","article-title":"The metabolomic quest for a biomarker in chronic kidney disease","volume":"11","author":"Davies","year":"2018","journal-title":"Clin Kidney J"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0062","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.gastro.2013.11.001","article-title":"Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease","volume":"146","author":"Dumas","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0063","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/ki.2013.328","article-title":"Identification of a urine metabolomic signature in patients with advanced-stage chronic kidney disease","volume":"85","author":"Posada-Ayala","year":"2014","journal-title":"Kidney Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0064","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1038\/s41467-019-09329-0","article-title":"Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan","volume":"10","author":"Chen","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0065","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1038\/ncomms3384","article-title":"Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity","volume":"4","author":"Li","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0066","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.cmet.2013.01.003","article-title":"Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist","volume":"17","author":"Sayin","year":"2013","journal-title":"Cell Metab"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0067","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.tibs.2006.08.002","article-title":"FXR, a multipurpose nuclear receptor","volume":"31","author":"Lee","year":"2006","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0068","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1074\/jbc.M209525200","article-title":"The farnesoid X-receptor is an essential regulator of cholesterol homeostasis","volume":"278","author":"Lambert","year":"2003","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0069","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1073\/pnas.0506982103","article-title":"Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice","volume":"103","author":"Zhang","year":"2006","journal-title":"Proc Natl Acad Sci U S A."},{"key":"10.1016\/j.jnutbio.2022.109053_bib0070","doi-asserted-by":"crossref","first-page":"G543","DOI":"10.1152\/ajpgi.90585.2008","article-title":"A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia","volume":"296","author":"Evans","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0071","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1210\/mend.15.10.0712","article-title":"Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids","volume":"15","author":"Kast","year":"2001","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0072","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1073\/pnas.0506982103","article-title":"Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice","volume":"103","author":"Zhang","year":"2006","journal-title":"Proc Natl Acad Sci U S A."},{"key":"10.1016\/j.jnutbio.2022.109053_bib0073","doi-asserted-by":"crossref","first-page":"14430","DOI":"10.3748\/wjg.v20.i39.14430","article-title":"FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation","volume":"20","author":"Yao","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0074","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000341485","article-title":"Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed Wistar rats","volume":"36","author":"Hu","year":"2012","journal-title":"Kidney Blood Press Res"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0075","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.kint.2020.01.028","article-title":"Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney disease","volume":"97","author":"Gryp","year":"2020","journal-title":"Kidney Int"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0076","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2005.10.010","article-title":"System level metabolic effects of a Schistosoma japonicum infection in the Syrian hamster","volume":"146","author":"Wang","year":"2006","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0077","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1210\/jc.2018-00947","article-title":"Urine tricarboxylic acid cycle metabolites predict progressive chronic kidney disease in type 2 diabetes","volume":"103","author":"Liu","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0078","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000447954","article-title":"Metabolomics in diabetic kidney disease: unraveling the biochemistry of a silent killer","volume":"44","author":"Darshi","year":"2016","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0079","doi-asserted-by":"crossref","first-page":"11433","DOI":"10.1038\/s41598-017-11759-z","article-title":"Identification of key metabolic changes during liver fibrosis progression in rats using a urine and serum metabolomics approach","volume":"7","author":"Chang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0080","doi-asserted-by":"crossref","first-page":"14752","DOI":"10.1038\/s41598-018-33018-5","article-title":"Gut colonization with methanogenic archaea lowers plasma trimethylamine n-oxide concentrations in apolipoprotein e-\/- mice","volume":"8","author":"Ramezani","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0081","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1161\/CIRCRESAHA.114.305680","article-title":"TMAO is both a biomarker and a renal toxin","volume":"116","author":"Fogelman","year":"2015","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2022.109053_bib0082","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/CIRCRESAHA.116.305360","article-title":"Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease","volume":"116","author":"Tang","year":"2015","journal-title":"Circ Res"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286322001243?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286322001243?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:38:02Z","timestamp":1760629082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286322001243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":82,"alternative-id":["S0955286322001243"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2022.109053","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Opisthorchis viverrini infection induces metabolic disturbances in hamsters fed with high fat\/high fructose diets: Implications for liver and kidney pathologies","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2022.109053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109053"}}