{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:01:26Z","timestamp":1792710086420,"version":"4.5.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:00:00Z","timestamp":1742256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.jnutbio.2025.109904","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:53:58Z","timestamp":1742554438000},"page":"109904","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["A red lentils-based synbiotic cookie exerts neuroprotective effects in a mouse model of Alzheimer's disease"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9542-4310","authenticated-orcid":false,"given":"Laura","family":"Bonfili","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5487-3997","authenticated-orcid":false,"given":"Francesco Maria","family":"Grasselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Cuccioloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Cecarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Lufrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Vittadini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Galosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorio","family":"Sonsini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4089-2483","authenticated-orcid":false,"given":"Massimo","family":"Ubaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan Louis","family":"Turck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Fernando da Costa","family":"Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Suchodolski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0461-1346","authenticated-orcid":false,"given":"Anna Maria","family":"Eleuteri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2025.109904_bib0001","series-title":"StatPearls","author":"Kumar","year":"2025"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0002","doi-asserted-by":"crossref","first-page":"4107","DOI":"10.1007\/s10072-022-06068-x","article-title":"Anxiety and depression in Alzheimer's disease: a systematic review of pathogenetic mechanisms and relation to cognitive decline","volume":"43","author":"Botto","year":"2022","journal-title":"Neurol Sci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0003","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1111\/febs.15571","article-title":"Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease","volume":"288","author":"Bonfili","year":"2021","journal-title":"FEBS J"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0004","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3233\/JAD-160826","article-title":"Updating the evidence on the association between serum cholesterol and risk of late-life dementia: review and meta-analysis","volume":"56","author":"Anstey","year":"2016","journal-title":"J Alzheimer's Dis"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0005","doi-asserted-by":"crossref","DOI":"10.3390\/metabo13020253","article-title":"High-density lipoprotein alterations in type 2 diabetes and obesity","volume":"13","author":"Denimal","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0006","doi-asserted-by":"crossref","first-page":"937056","DOI":"10.3389\/fnmol.2022.937056","article-title":"Cholesterol as a key player in amyloid \u03b2-mediated toxicity in Alzheimer\u2019s disease","volume":"15","author":"Rudajev","year":"2022","journal-title":"Front Mol Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0007","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.2337\/diabetes.53.5.1253","article-title":"Triglycerides induce leptin resistance at the blood-brain barrier","volume":"53","author":"Banks","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0008","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.neurobiolaging.2020.04.003","article-title":"Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model","volume":"92","author":"Ferreiro","year":"2020","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0009","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00424-020-02441-x","article-title":"Glucose transporters in brain in health and disease","volume":"472","author":"Koepsell","year":"2020","journal-title":"Pfl\u00fcgers Archiv \u2013 Eur J Physiol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e11738","article-title":"Decreased resistin plasmatic concentrations in patients with Alzheimer's disease: a case-control study","volume":"8","author":"Marcinno","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0011","doi-asserted-by":"crossref","first-page":"59","DOI":"10.9758\/cpn.2017.15.1.59","article-title":"The serum levels of resistin and its relationship with other proinflammatory cytokines in patients with Alzheimer's disease","volume":"15","author":"Demirci","year":"2017","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0012","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neuroscience.2013.02.062","article-title":"Leptin and ghrelin prevent hippocampal dysfunction induced by Abeta oligomers","volume":"241","author":"Martins","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0013","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s11011-024-01369-w","article-title":"The connection between gut microbiota and its metabolites with neurodegenerative diseases in humans","volume":"39","author":"Fabi","year":"2024","journal-title":"Metabolic Brain Dis"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0014","doi-asserted-by":"crossref","DOI":"10.1515\/revneuro-2024-0113","article-title":"The interplay between gut microbiota composition and dementia","author":"Ghannadzadeh Kermani pour","year":"2025","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0015","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13195-023-01218-5","article-title":"A peripheral signature of Alzheimer's disease featuring microbiota-gut-brain axis markers","volume":"15","author":"Marizzoni","year":"2023","journal-title":"Alzheimers Res Ther"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0016","doi-asserted-by":"crossref","first-page":"4916","DOI":"10.1093\/brain\/awad303","article-title":"Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis","volume":"146","author":"Grabrucker","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0017","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/s12276-023-01146-2","article-title":"Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies","volume":"56","author":"Seo","year":"2024","journal-title":"Exp Mol Med"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0018","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/s41435-021-00126-8","article-title":"The aging gut microbiome and its impact on host immunity","volume":"22","author":"Bosco","year":"2021","journal-title":"Genes & Immunity"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0019","doi-asserted-by":"crossref","first-page":"7152","DOI":"10.1021\/acs.jafc.0c02807","article-title":"Anti-neuroinflammatory effect of short-chain fatty acid acetate against Alzheimer's disease via upregulating GPR41 and inhibiting ERK\/JNK\/NF-\u03bab","volume":"68","author":"Liu","year":"2020","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0020","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jnutbio.2019.03.021","article-title":"Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity","volume":"69","author":"Srivastav","year":"2019","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0021","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1038\/s41598-017-02587-2","article-title":"Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels","volume":"7","author":"Bonfili","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0022","doi-asserted-by":"crossref","first-page":"7987","DOI":"10.1007\/s12035-018-0973-4","article-title":"SLAB51 Probiotic formulation activates SIRT1 pathway promoting antioxidant and neuroprotective effects in an AD mouse model","volume":"55","author":"Bonfili","year":"2018","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0023","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neurobiolaging.2019.11.004","article-title":"Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease","volume":"87","author":"Bonfili","year":"2020","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0024","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.clnu.2022.01.025","article-title":"Gut microbiota modulation in Alzheimer's disease: focus on lipid metabolism","volume":"41","author":"Bonfili","year":"2022","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0025","doi-asserted-by":"crossref","first-page":"100124","DOI":"10.1016\/j.crphys.2024.100124","article-title":"Health-promoting benefits of lentils: anti-inflammatory and anti-microbial effects","volume":"7","author":"Alexander","year":"2024","journal-title":"Curr Res Physiology"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104873","article-title":"Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial","volume":"98","author":"Zhang","year":"2023","journal-title":"eBioMedicine"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0027","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3920\/BM2018.0170","article-title":"Effects of bifidobacterium breve A1 on the cognitive function of older adults with memory complaints: a randomised, double-blind, placebo-controlled trial","volume":"10","author":"Kobayashi","year":"2019","journal-title":"Benef Microbes"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0028","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/sj.ejcn.1602546","article-title":"Impact of consuming a milk drink containing a probiotic on mood and cognition","volume":"61","author":"Benton","year":"2007","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0029","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3389\/fnagi.2016.00256","article-title":"Effect of probiotic supplementation on cognitive function and metabolic status in Alzheimer's Disease: A randomized, double-blind and controlled trial","volume":"8","author":"Akbari","year":"2016","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0030","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1017\/S0007114511000158","article-title":"Dairy constituents and neurocognitive health in ageing","volume":"106","author":"Camfield","year":"2011","journal-title":"Br J Nutr"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0031","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3389\/fnut.2019.00038","article-title":"Variability in prebiotic carbohydrates in different market classes of chickpea, common bean, and lentil collected from the American local market","volume":"6","author":"Siva","year":"2019","journal-title":"Front Nutr"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0032","doi-asserted-by":"crossref","first-page":"100761","DOI":"10.1016\/j.afres.2025.100761","article-title":"Development of sugar- and fat-reduced pulse cookies with improved predicted glycemic behavior","volume":"5","author":"Suo","year":"2025","journal-title":"Applied Food Research"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0033","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3920\/BM2020.0028","article-title":"A systematic review of the effect of dietary pulses on microbial populations inhabiting the human gut","volume":"11","author":"Marinangeli","year":"2020","journal-title":"Benef Microbes"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0034","doi-asserted-by":"crossref","first-page":"5080","DOI":"10.1111\/ijfs.15298","article-title":"Semi-solid fibre syrup for sugar reduction in cookies","volume":"56","author":"Carcelli","year":"2021","journal-title":"Int J Food Sci Technol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0035","doi-asserted-by":"crossref","first-page":"3836","DOI":"10.1002\/jsfa.8899","article-title":"Structured emulsions as butter substitutes: effects on physicochemical and sensory attributes of shortbread cookies","volume":"98","author":"Curti","year":"2018","journal-title":"J Sci Food Agric"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0036","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1038\/s41596-018-0119-1","article-title":"INFOGEST static in vitro simulation of gastrointestinal food digestion","volume":"14","author":"Brodkorb","year":"2019","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0037","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0038","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nature Methods"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0039","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nmeth.3869","article-title":"DADA2: High-resolution sample inference from Illumina amplicon data","volume":"13","author":"Callahan","year":"2016","journal-title":"Nature Methods"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0040","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.1038\/s41467-020-17041-7","article-title":"Analysis of compositions of microbiomes with bias correction","volume":"11","author":"Lin","year":"2020","journal-title":"Nature Commun"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0041","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41587-020-0548-6","article-title":"PICRUSt2 for prediction of metagenome functions","volume":"38","author":"Douglas","year":"2020","journal-title":"Nature Biotechnology"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0042","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4239\/wjd.v13.i4.319","article-title":"Cognitive disorder and dementia in type 2 diabetes mellitus","volume":"13","author":"Ortiz","year":"2022","journal-title":"World J Diabetes"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0043","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1038\/oby.2004.185","article-title":"Sexual dimorphism and regulation of resistin, adiponectin, and leptin expression in the mouse","volume":"12","author":"Gui","year":"2004","journal-title":"Obes Res"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0044","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/19390211.2020.1761506","article-title":"Potential probiotic or trigger of gut inflammation \u2013The janus-faced nature of cannabidiol-rich cannabis extract","volume":"17","author":"Skinner","year":"2020","journal-title":"J Dietary Supplements"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0045","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13808","article-title":"Vaccinium bracteatum thunb. Fruit extract reduces high-fat diet-induced obesity with modulation of the gut microbiota in obese mice","volume":"45","author":"Song","year":"2021","journal-title":"J Food Biochem"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0046","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3892\/etm.2021.9862","article-title":"Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic\u2011associated fatty liver disease in mice","volume":"21","author":"Kang","year":"2021","journal-title":"Exp Therap Med"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0047","doi-asserted-by":"crossref","DOI":"10.3390\/nu15214631","article-title":"Understanding the gut-brain axis and its therapeutic implications for neurodegenerative disorders","volume":"15","author":"Zheng","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0048","doi-asserted-by":"crossref","first-page":"46","DOI":"10.20517\/mrr.2024.48","article-title":"Synergistic vs. complementary synbiotics: the complexity of discriminating synbiotic concepts using a lactiplantibacillus plantarum exemplary study","volume":"3","author":"Kleerebezem","year":"2024","journal-title":"Microbiome Res Rep"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0049","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.bbr.2015.04.012","article-title":"Early detection of cognitive deficits in the 3xTg-AD mouse model of Alzheimer's disease","volume":"289","author":"Stover","year":"2015","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0050","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1001\/archneur.61.5.705","article-title":"Relation of plasma lipids to Alzheimer disease and vascular dementia","volume":"61","author":"Reitz","year":"2004","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0051","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201700403","article-title":"Evaluation of the hypocholesterolemic effect and prebiotic activity of a lentil (Lens culinaris Medik) extract","volume":"61","author":"Micioni Di Bonaventura","year":"2017","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0052","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.3390\/ijms18112390","article-title":"Polyphenol-rich lentils and their health promoting effects","volume":"18","author":"Ganesan","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0053","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.3390\/foods10061431","article-title":"Synergistic effects of the Jackfruit seed sourced resistant starch and bifidobacterium pseudolongum subsp. Globosum on suppression of hyperlipidemia in mice","volume":"10","author":"Zhang","year":"2021","journal-title":"Foods"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0054","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.3233\/JAD-150982","article-title":"Inhibition of cholesterol biosynthesis reduces gamma-secretase activity and amyloid-beta generation","volume":"51","author":"Kim","year":"2016","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0055","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1523\/JNEUROSCI.0046-08.2008","article-title":"Short-term memory and the human hippocampus","volume":"28","author":"Kumaran","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0056","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3233\/JAD-2010-101263","article-title":"Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-beta1-42 oligomer-injected mice","volume":"23","author":"Moon","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0057","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3389\/fnins.2019.00378","article-title":"Role of leptin in mood disorder and neurodegenerative disease","volume":"13","author":"Zou","year":"2019","journal-title":"Front Neurosci"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0058","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.bcp.2018.07.021","article-title":"Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential","volume":"155","author":"Pathak","year":"2018","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0059","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s40168-022-01307-x","article-title":"Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake","volume":"10","author":"Holmes","year":"2022","journal-title":"Microbiome"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0060","doi-asserted-by":"crossref","first-page":"G53","DOI":"10.1152\/ajpgi.00346.2017","article-title":"The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon","volume":"315","author":"Christiansen","year":"2018","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0061","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.3390\/jcm9061713","article-title":"Link between diabetes and Alzheimer\u2019s disease due to the shared amyloid aggregation and deposition involving both neurodegenerative changes and neurovascular damages","volume":"9","author":"Stanciu","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0062","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/oby.20632","article-title":"Combined effects of oligofructose and bifidobacterium animalis on gut microbiota and glycemia in obese rats","volume":"22","author":"Bomhof","year":"2014","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0063","article-title":"Cognitive dysfunction in diabetes: abnormal glucose metabolic regulation in the brain","volume":"14","author":"Zhang","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0064","doi-asserted-by":"crossref","first-page":"E242","DOI":"10.1152\/ajpendo.90388.2008","article-title":"The facilitative glucose transporter GLUT3: 20 years of distinction","volume":"295","author":"Simpson","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jnutbio.2025.109904_bib0065","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.febslet.2007.12.035","article-title":"Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease","volume":"582","author":"Liu","year":"2008","journal-title":"FEBS Letters"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325000671?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325000671?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T05:06:01Z","timestamp":1760072761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286325000671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":65,"alternative-id":["S0955286325000671"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.109904","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A red lentils-based synbiotic cookie exerts neuroprotective effects in a mouse model of Alzheimer's disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.109904","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109904"}}