{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T10:21:20Z","timestamp":1779013280671,"version":"3.51.4"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2024-BS-180"],"award-info":[{"award-number":["2024-BS-180"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["YXJL-2022-0105-0149"],"award-info":[{"award-number":["YXJL-2022-0105-0149"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012131","name":"Department of Science and Technology of Liaoning Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012131","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012465","name":"Dalian Medical University","doi-asserted-by":"publisher","award":["508025"],"award-info":[{"award-number":["508025"]}],"id":[{"id":"10.13039\/501100012465","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jnutbio.2025.110002","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T19:26:30Z","timestamp":1749669990000},"page":"110002","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Fucoxanthin ameliorates vascular remodeling via attenuating oxidative stress in hypoxic pulmonary hypertension rats"],"prefix":"10.1016","volume":"145","author":[{"given":"Xu","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jina","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqin","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinjin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dingyou","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junxia","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7798-1333","authenticated-orcid":false,"given":"Yuke","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhilong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Hasnain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Sui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6250-5202","authenticated-orcid":false,"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhui","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jnutbio.2025.110002_bib0001","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41572-024-00493-2","article-title":"Pulmonary hypertension","volume":"10","author":"Mocumbi","year":"2024","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0002","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1164\/rccm.202302-0327SO","article-title":"Pulmonary Hypertension: a contemporary review","volume":"208","author":"Johnson","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0003","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S2213-2600(15)00543-3","article-title":"A global view of pulmonary hypertension","volume":"4","author":"Hoeper","year":"2016","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0004","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1161\/01.RES.0000243584.45145.3f","article-title":"Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms","volume":"99","author":"Stenmark","year":"2006","journal-title":"Circ Res"},{"issue":"4","key":"10.1016\/j.jnutbio.2025.110002_bib0005","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01324-2024","article-title":"Definition, classification and diagnosis of pulmonary hypertension","volume":"64","author":"Kovacs","year":"2024","journal-title":"Eur Respir J"},{"issue":"11","key":"10.1016\/j.jnutbio.2025.110002_bib0006","doi-asserted-by":"crossref","first-page":"6205","DOI":"10.3390\/ijms23116205","article-title":"AMPK and the challenge of treating hypoxic pulmonary hypertension","volume":"23","author":"Flores","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0007","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.healun.2022.12.012","article-title":"Vascular pathobiology of pulmonary hypertension","volume":"42","author":"Gallardo-Vara","year":"2023","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0008","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3390\/antiox11020267","article-title":"Oxidative stress and diseases associated with high-altitude exposure","volume":"11","author":"Pena","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0009","article-title":"Melatonin attenuates dasatinib-aggravated hypoxic pulmonary hypertension via inhibiting pulmonary vascular remodeling","volume":"9","author":"Wang","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0010","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/jpi.12184","article-title":"Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cells","volume":"57","author":"Jin","year":"2014","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101536","article-title":"NADPH oxidases and HIF1 promote cardiac dysfunction and pulmonary hypertension in response to glucocorticoid excess","volume":"34","author":"Kracun","year":"2020","journal-title":"Redox Biol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0012","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1091\/mbc.e09-12-1003","article-title":"The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1","volume":"21","author":"Diebold","year":"2010","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0013","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1172\/JCI137560","article-title":"Hypoxia-inducible factors and obstructive sleep apnea","volume":"130","author":"Prabhakar","year":"2020","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.jnutbio.2025.110002_bib0014","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3390\/md20060370","article-title":"Fucoxanthin is a potential therapeutic agent for the treatment of breast cancer","volume":"20","author":"Lau","year":"2022","journal-title":"Mar Drugs"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0015","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00394-023-03256-z","article-title":"Fucoxanthin extract ameliorates obesity associated with modulation of bile acid metabolism and gut microbiota in high-fat-diet fed mice","volume":"63","author":"Hao","year":"2024","journal-title":"Eur J Nutr"},{"issue":"8","key":"10.1016\/j.jnutbio.2025.110002_bib0016","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.3390\/nu15081954","article-title":"A review of the effects of fucoxanthin on NAFLD","volume":"15","author":"Sayuti","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0017","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1142\/S0192415X24500691","article-title":"Fucoxanthin prevents lipopolysaccharide-induced acute lung injury by inhibiting ferroptosis via Nrf2\/STAT3 and glutathione pathways","volume":"52","author":"Ding","year":"2024","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0018","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1002\/tox.23587","article-title":"Fucoxanthin decreases lipopolysaccharide-induced acute lung injury through the inhibition of RhoA activation and the NF-kappaB pathway","volume":"37","author":"Lee","year":"2022","journal-title":"Environ Toxicol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110370","article-title":"Fucoxanthin alleviated atherosclerosis by regulating PI3K\/AKT and TLR4\/NFkappaB mediated pyroptosis in endothelial cells","volume":"120","author":"Cui","year":"2023","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0020","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.3390\/md9101806","article-title":"Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to Human health","volume":"9","author":"Peng","year":"2011","journal-title":"Mar Drugs"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0021","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1161\/ATVBAHA.118.311714","article-title":"Aqp-1 gene knockout attenuates hypoxic pulmonary hypertension of mice","volume":"39","author":"Liu","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0022","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1161\/01.CIR.0000018947.95555.65","article-title":"Steroid receptor coactivator-3 is required for inhibition of neointima formation by estrogen","volume":"105","author":"Yuan","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0023","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jnutbio.2016.07.006","article-title":"Grape seed procyanidin extract attenuates hypoxic pulmonary hypertension by inhibiting oxidative stress and pulmonary arterial smooth muscle cells proliferation","volume":"36","author":"Jin","year":"2016","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0024","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011628","article-title":"Influence of 2-methoxyestradiol and sex on hypoxia-induced pulmonary hypertension and hypoxia-inducible factor-1-alpha","volume":"8","author":"Docherty","year":"2019","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110002_bib0025","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1111\/all.16361","article-title":"Blocking the HIF-1alpha\/glycolysis axis inhibits allergic airway inflammation by reducing ILC2 metabolism and function","volume":"80","author":"Zhang","year":"2025","journal-title":"Allergy"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.109182","article-title":"Sulforaphane alleviated vascular remodeling in hypoxic pulmonary hypertension via inhibiting inflammation and oxidative stress","volume":"111","author":"Pan","year":"2023","journal-title":"J Nutr Biochem"},{"issue":"40","key":"10.1016\/j.jnutbio.2025.110002_bib0027","doi-asserted-by":"crossref","first-page":"eabq0959","DOI":"10.1126\/sciadv.abq0959","article-title":"NIR-photocatalytic regulation of arthritic synovial microenvironment","volume":"8","author":"Zhao","year":"2022","journal-title":"Sci Adv"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0028","doi-asserted-by":"crossref","first-page":"L229","DOI":"10.1152\/ajplung.00238.2014","article-title":"The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes","volume":"308","author":"Pugliese","year":"2015","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0029","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1161\/CIRCRESAHA.113.301141","article-title":"Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension","volume":"115","author":"Rabinovitch","year":"2014","journal-title":"Circulation Research"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0030","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1161\/CIRCRESAHA.115.301146","article-title":"Pulmonary arterial hypertension: the clinical syndrome","volume":"115","author":"Lai","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0031","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.yexmp.2010.06.010","article-title":"Contribution of myocardin in the hypoxia-induced phenotypic switching of rat pulmonary arterial smooth muscle cells","volume":"89","author":"Jie","year":"2010","journal-title":"Exp Mol Pathol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0032","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1080\/01902148.2024.2398994","article-title":"Exosomes derived from hypoxic alveolar epithelial cells promote the phenotypic transformation of pulmonary artery smooth muscle cells via the Rap1 pathway","volume":"50","author":"Sun","year":"2024","journal-title":"Exp Lung Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0033","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.2147\/DDDT.S275000","article-title":"PTBP1 Targets ILK to regulate the hypoxia-induced phenotypic transformation of pulmonary artery smooth muscle cells","volume":"15","author":"Yan","year":"2021","journal-title":"Drug Des Devel Ther."},{"key":"10.1016\/j.jnutbio.2025.110002_bib0034","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.canlet.2017.06.031","article-title":"p27(Kip1) and human cancers: a reappraisal of a still enigmatic protein","volume":"403","author":"Bencivenga","year":"2017","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0035","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.bbrc.2006.05.060","article-title":"Gene expression of cyclin-dependent kinase inhibitors and effect of heparin on their expression in mice with hypoxia-induced pulmonary hypertension","volume":"345","author":"Yu","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0036","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1165\/ajrcmb.25.5.4592","article-title":"p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation","volume":"25","author":"Fouty","year":"2001","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0037","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12890-018-0680-y","article-title":"NOX4 expression and distal arteriolar remodeling correlate with pulmonary hypertension in COPD","volume":"18","author":"Guo","year":"2018","journal-title":"BMC Pulmonary Medicine"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0038","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1161\/HYPERTENSIONAHA.116.07668","article-title":"Nicotinamide adenine dinucleotide phosphate oxidase-mediated redox signaling and vascular remodeling by 16alpha-hydroxyestrone in Human pulmonary artery cells: implications in pulmonary arterial hypertension","volume":"68","author":"Hood","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0039","doi-asserted-by":"crossref","first-page":"942","DOI":"10.7150\/ijms.16810","article-title":"Resveratrol alleviate hypoxic pulmonary hypertension via anti-inflammation and anti-oxidant pathways in rats","volume":"13","author":"Xu","year":"2016","journal-title":"Int J Med Sci"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0040","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1002\/ptr.5683","article-title":"Fucoxanthin suppresses lipid accumulation and ROS production during differentiation in 3T3-L1 adipocytes","volume":"30","author":"Seo","year":"2016","journal-title":"Phytother Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0041","doi-asserted-by":"crossref","first-page":"L109","DOI":"10.1152\/ajplung.00309.2009","article-title":"SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertension","volume":"299","author":"Farrow","year":"2010","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0042","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/pr.2015.166","article-title":"Lack of EC-SOD worsens alveolar and vascular development in a neonatal mouse model of bleomycin-induced bronchopulmonary dysplasia and pulmonary hypertension","volume":"78","author":"Delaney","year":"2015","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0043","doi-asserted-by":"crossref","first-page":"L868","DOI":"10.1152\/ajplung.00096.2014","article-title":"Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension","volume":"307","author":"Nozik-Grayck","year":"2014","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110002_bib0044","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3390\/cells12050798","article-title":"Transcriptional response to hypoxia: the role of HIF-1-associated Co-regulators","volume":"12","author":"Yfantis","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0045","article-title":"Hypoxia-inducible factor 1-alpha (HIF-1alpha): an essential regulator in cellular metabolic control","volume":"16","author":"Basheeruddin","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0046","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1161\/CIRCRESAHA.119.315229","article-title":"Identification of Celastramycin as a novel therapeutic agent for pulmonary arterial hypertension","volume":"125","author":"Kurosawa","year":"2019","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0047","doi-asserted-by":"crossref","first-page":"5638","DOI":"10.1172\/JCI137558","article-title":"Hypoxia-inducible factor signaling in pulmonary hypertension","volume":"130","author":"Pullamsetti","year":"2020","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0048","article-title":"Dan-Shen-Yin granules prevent hypoxia-induced pulmonary hypertension via STAT3\/HIF-1alpha\/VEGF and FAK\/AKT signaling pathways","volume":"13","author":"Wang","year":"2022","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0049","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1161\/hh1301.092678","article-title":"Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase","volume":"89","author":"Gorlach","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.jnutbio.2025.110002_bib0050","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/s10020-024-00975-9","article-title":"PI3K p85alpha\/HIF-1alpha accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy","volume":"30","author":"Chen","year":"2024","journal-title":"Mol Med"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001652?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001652?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:11:20Z","timestamp":1762456280000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286325001652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":50,"alternative-id":["S0955286325001652"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110002","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fucoxanthin ameliorates vascular remodeling via attenuating oxidative stress in hypoxic pulmonary hypertension rats","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110002"}}