{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:02:38Z","timestamp":1789585358030,"version":"build-2803163510"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","award":["2022CXPT022"],"award-info":[{"award-number":["2022CXPT022"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008279","name":"Ludong University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008279","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jnutbio.2025.110017","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T04:41:59Z","timestamp":1751431319000},"page":"110017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Calcitriol\/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice"],"prefix":"10.1016","volume":"145","author":[{"given":"Jiayu","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianlong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0534-6142","authenticated-orcid":false,"given":"Xingxiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2025.110017_bib0001","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1016\/j.cmet.2021.09.004","article-title":"\"Sweet death\": fructose as a metabolic toxin that targets the gut-liver axis","volume":"33","author":"Febbraio","year":"2021","journal-title":"Cell Metab"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0002","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/560620","article-title":"Fructose induced endotoxemia in pediatric nonalcoholic fatty liver disease","author":"Jin","year":"2014","journal-title":"Int J Hepatol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0003","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3945\/ajcn.112.057331","article-title":"Dietary fructose induces endotoxemia and hepatic injury in calorically controlled primates","volume":"98","author":"Kavanagh","year":"2013","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0004","doi-asserted-by":"crossref","first-page":"770","DOI":"10.3945\/jn.116.242859","article-title":"Intestinal barrier function and the gut microbiome are differentially affected in mice fed a Western-style diet or drinking water supplemented with fructose","volume":"147","author":"Volynets","year":"2017","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0005","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.chom.2014.11.010","article-title":"Diet dominates host genotype in shaping the murine gut microbiota","volume":"17","author":"Carmody","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0006","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nature12820","article-title":"Diet rapidly and reproducibly alters the human gut microbiome","volume":"505","author":"David","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0007","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jcmgh.2020.09.008","article-title":"Dietary fructose alters the composition, localization, and metabolism of gut microbiota in association with worsening colitis","volume":"11","author":"Montrose","year":"2021","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0008","first-page":"1487","article-title":"A high\u2011fructose diet induces epithelial barrier dysfunction and exacerbates the severity of dextran sulfate sodium\u2011induced colitis","volume":"43","author":"Kawabata","year":"2019","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0009","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.jnutbio.2015.05.011","article-title":"Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time","volume":"26","author":"Sellmann","year":"2015","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0010","doi-asserted-by":"crossref","DOI":"10.3390\/nu10060761","article-title":"High-glucose or -fructose diet cause changes of the gut microbiota and metabolic disorders in mice without body weight change","volume":"10","author":"Do","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0011","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1038\/s42255-020-0261-2","article-title":"Fructose stimulated de novo lipogenesis is promoted by inflammation","volume":"2","author":"Todoric","year":"2020","journal-title":"Nat Metab"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0012","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1002\/hep.30652","article-title":"Fructose promotes leaky gut, endotoxemia, and liver fibrosis through ethanol-inducible cytochrome P450-2E1-mediated oxidative and nitrative stress","volume":"73","author":"Cho","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0013","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1146\/annurev-pharmtox-010510-100611","article-title":"Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D","volume":"51","author":"Krishnan","year":"2011","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0014","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/ibd\/izy092","article-title":"Ancient nuclear receptor VDR with new functions: microbiome and inflammation","volume":"24","author":"Bakke","year":"2018","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0015","doi-asserted-by":"crossref","first-page":"8127","DOI":"10.3390\/nu7095383","article-title":"Regulation of dendritic cell function by vitamin D","volume":"7","author":"Barragan","year":"2015","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110017_bib0016","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.imbio.2012.07.018","article-title":"25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism","volume":"217","author":"Korf","year":"2012","journal-title":"Immunobiology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0017","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.3945\/jn.113.180794","article-title":"Cantorna MT: vitamin D regulates the gut microbiome and protects mice from dextran sodium sulfate-induced colitis","volume":"143","author":"Ooi","year":"2013","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0018","doi-asserted-by":"crossref","first-page":"6294","DOI":"10.1016\/j.vaccine.2014.08.075","article-title":"Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells","volume":"32","author":"Bakdash","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0019","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1053\/j.gastro.2020.11.015","article-title":"Paneth cell alertness to pathogens maintained by vitamin D receptors","volume":"160","author":"Lu","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0020","doi-asserted-by":"crossref","first-page":"G208","DOI":"10.1152\/ajpgi.00398.2007","article-title":"Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier","volume":"294","author":"Kong","year":"2008","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0021","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1172\/JCI65842","article-title":"Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis","volume":"123","author":"Liu","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0022","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/hep.30937","article-title":"Vitamin D receptor activation in liver macrophages ameliorates hepatic inflammation, steatosis, and insulin resistance in mice","volume":"71","author":"Dong","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118666","article-title":"MicroRNA-125a\/VDR axis impaired autophagic flux and contributed to fibrosis in a CCL4-induced mouse model and patients with liver cirrhosis","volume":"264","author":"He","year":"2021","journal-title":"Life Sci"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0024","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/nprot.2017.044","article-title":"Chemically induced mouse models of acute and chronic intestinal inflammation","volume":"12","author":"Wirtz","year":"2017","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0025","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12574","article-title":"Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice","volume":"67","author":"Gao","year":"2019","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0026","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3109\/10409231003667500","article-title":"Genetic control of de novo lipogenesis: role in diet-induced obesity","volume":"45","author":"Strable","year":"2010","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0027","doi-asserted-by":"crossref","first-page":"6ra14","DOI":"10.1126\/scitranslmed.3000322","article-title":"The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice","volume":"1","author":"Turnbaugh","year":"2009","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0028","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.3389\/fimmu.2017.01159","article-title":"Fructose: a dietary sugar in crosstalk with microbiota contributing to the development and progression of non-alcoholic liver disease","volume":"8","author":"Lambertz","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0029","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/hep.23122","article-title":"Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice","volume":"50","author":"Spruss","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0030","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/labinvest.2012.75","article-title":"Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function","volume":"92","author":"Spruss","year":"2012","journal-title":"Lab Invest"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0031","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1080\/10408398.2017.1353479","article-title":"Nutrition, inflammation and liver-spleen axis","volume":"58","author":"Barrea","year":"2018","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0032","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1136\/gut.2004.047092","article-title":"Increased gut permeability in Crohn's disease: is TNF the link?","volume":"53","author":"Gibson","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0033","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/ncpgasthep0259","article-title":"Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases","volume":"2","author":"Fasano","year":"2005","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0034","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1053\/j.gastro.2013.04.011","article-title":"TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis","volume":"145","author":"Su","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0035","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.toxlet.2019.08.024","article-title":"The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1\/Nrf2 and NF-\u03bab dependent mechanism in Caco-2 cells","volume":"316","author":"Yao","year":"2019","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0036","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1210\/en.2017-00748","article-title":"Gut epithelial vitamin D receptor regulates microbiota-dependent mucosal inflammation by suppressing intestinal epithelial cell apoptosis","volume":"159","author":"He","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0037","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1016\/j.tiv.2015.08.006","article-title":"Increased oxidative stress and apoptosis in peripheral blood mononuclear cells of fructose-fed rats","volume":"29","author":"Porto","year":"2015","journal-title":"Toxicol In Vitro"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0038","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/cei.13299","article-title":"High fructose-induced metabolic changes enhance inflammation in human dendritic cells","volume":"197","author":"Jaiswal","year":"2019","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0039","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/s41467-021-21461-4","article-title":"Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation","volume":"12","author":"Jones","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0040","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1080\/15548627.2016.1235124","article-title":"Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice","volume":"12","author":"Han","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0041","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4161\/auto.27004","article-title":"Autophagy activation reduces renal tubular injury induced by urinary proteins","volume":"10","author":"Liu","year":"2014","journal-title":"Autophagy"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0042","doi-asserted-by":"crossref","first-page":"7741","DOI":"10.1073\/pnas.1407001111","article-title":"Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense","volume":"111","author":"Lassen","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0043","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1038\/emboj.2013.233","article-title":"Autophagy proteins control goblet cell function by potentiating reactive oxygen species production","volume":"32","author":"Patel","year":"2013","journal-title":"Embo J"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0044","doi-asserted-by":"crossref","first-page":"e0172","DOI":"10.1097\/MD.0000000000010172","article-title":"Autophagy, apoptosis, vitamin D, and vitamin D receptor in hepatocellular carcinoma associated with hepatitis C virus","volume":"97","author":"Abdel-Mohsen","year":"2018","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0045","doi-asserted-by":"crossref","first-page":"11845","DOI":"10.1096\/fj.201900727R","article-title":"Imbalance of autophagy and apoptosis in intestinal epithelium lacking the vitamin D receptor","volume":"33","author":"Lu","year":"2019","journal-title":"Faseb J"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0046","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1007\/s00018-016-2403-y","article-title":"The cellular autophagy\/apoptosis checkpoint during inflammation","volume":"74","author":"Messer","year":"2017","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0047","first-page":"686","article-title":"Vitamin D(3)\/VDR inhibits inflammation through NF-\u03bab pathway accompanied by resisting apoptosis and inducing autophagy in abalone haliotis discus hannai","volume":"177","author":"Huang","year":"2021","journal-title":"Cell Biol Toxicol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0048","doi-asserted-by":"crossref","first-page":"686","DOI":"10.2353\/ajpath.2010.090998","article-title":"Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine","volume":"177","author":"Wu","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0049","doi-asserted-by":"crossref","first-page":"19450","DOI":"10.1074\/jbc.M113.467670","article-title":"Vitamin D receptor inhibits nuclear factor \u03bab activation by interacting with i\u03bab kinase \u03b2 protein","volume":"288","author":"Chen","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0050","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.tcb.2012.08.001","article-title":"The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation","volume":"22","author":"Tornatore","year":"2012","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0051","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1152\/physrev.00019.2009","article-title":"Metabolic effects of fructose and the worldwide increase in obesity","volume":"90","author":"Tappy","year":"2010","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0052","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1172\/JCI99009","article-title":"Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling","volume":"128","author":"Softic","year":"2018","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0053","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1007\/s10620-016-4054-0","article-title":"Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease","volume":"61","author":"Softic","year":"2016","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0054","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/j.cmet.2021.09.010","article-title":"Molecular aspects of fructose metabolism and metabolic disease","volume":"33","author":"Herman","year":"2021","journal-title":"Cell Metab"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0055","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/hep.31699","article-title":"Vitamin d-Liver Disease Association: biological basis and mechanisms of action","volume":"74","author":"Triantos","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0056","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.biopha.2018.10.140","article-title":"Vitamin D and liver fibrosis: molecular mechanisms and clinical studies","volume":"109","author":"Udomsinprasert","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0057","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.bbadis.2017.01.001","article-title":"Vitamin D in liver disease: current evidence and potential directions","volume":"1863","author":"Elangovan","year":"2017","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0058","first-page":"297","article-title":"Vitamin D deficiency in patients with liver cirrhosis","volume":"29","author":"Konstantakis","year":"2016","journal-title":"Ann Gastroenterol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0059","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1074\/jbc.RA119.011487","article-title":"Vitamin D receptor targets hepatocyte nuclear factor 4\u03b1 and mediates protective effects of vitamin D in nonalcoholic fatty liver disease","volume":"295","author":"Zhang","year":"2020","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0060","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s40168-019-0713-7","article-title":"Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids","volume":"7","author":"Li","year":"2019","journal-title":"Microbiome"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0061","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aay6218","article-title":"Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice","volume":"12","author":"Khan","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0062","doi-asserted-by":"crossref","first-page":"8456","DOI":"10.1038\/s41598-022-11819-z","article-title":"Characterizing the mucin-degrading capacity of the human gut microbiota","volume":"12","author":"Glover","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0063","doi-asserted-by":"crossref","first-page":"254","DOI":"10.4161\/gmic.1.4.12778","article-title":"Mucin-bacterial interactions in the human oral cavity and digestive tract","volume":"1","author":"Derrien","year":"2010","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0064","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202000937","article-title":"Active vitamin D(3) treatment attenuated bacterial translocation via improving intestinal barriers in cirrhotic rats","volume":"65","author":"Lee","year":"2021","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0065","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3945\/jn.116.238816","article-title":"Early-life sugar consumption affects the rat microbiome independently of obesity","volume":"147","author":"Noble","year":"2017","journal-title":"J Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0066","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.3389\/fmicb.2016.01706","article-title":"Mucosal prevalence and interactions with the epithelium indicate commensalism of Sutterella spp","volume":"7","author":"Hiippala","year":"2016","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0067","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027076","article-title":"A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease","volume":"6","author":"Mukhopadhya","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0068","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.1039\/C9FO01046G","article-title":"Gut microbiota might be a crucial factor in deciphering the metabolic benefits of perinatal genistein consumption in dams and adult female offspring","volume":"10","author":"Zhou","year":"2019","journal-title":"Food Funct"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0069","doi-asserted-by":"crossref","DOI":"10.3390\/nu12103197","article-title":"A high-fat diet increases gut microbiota biodiversity and energy expenditure due to nutrient difference","volume":"12","author":"Wang","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0070","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1039\/C8FO02364F","article-title":"Anti-inflammation effects of fucosylated chondroitin sulphate from Acaudina molpadioides by altering gut microbiota in obese mice","volume":"10","author":"Hu","year":"2019","journal-title":"Food Funct"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0071","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2020.1832857","article-title":"Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice","volume":"12","author":"Ma","year":"2020","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0072","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1080\/10408398.2018.1517725","article-title":"A next generation probiotic, akkermansia muciniphila","volume":"59","author":"Zhai","year":"2019","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0073","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1126\/science.abc3421","article-title":"Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy","volume":"369","author":"Mager","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0074","doi-asserted-by":"crossref","first-page":"7619","DOI":"10.1021\/acs.jafc.1c01781","article-title":"Protective effects of microbiome-derived inosine on lipopolysaccharide-induced acute liver damage and inflammation in mice via mediating the TLR4\/NF-\u03bab pathway","volume":"69","author":"Guo","year":"2021","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jnutbio.2025.110017_bib0075","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1136\/gutjnl-2014-307436","article-title":"Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis","volume":"64","author":"Wu","year":"2015","journal-title":"Gut"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001809?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001809?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:13:33Z","timestamp":1762456413000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286325001809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":75,"alternative-id":["S0955286325001809"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110017","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Calcitriol\/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110017"}}