{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:26:58Z","timestamp":1780100818254,"version":"3.54.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jnutbio.2025.110030","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T16:59:43Z","timestamp":1752598783000},"page":"110030","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Effect of the early introduction of trophic donor human breast milk on the preservation of postoperative gut functions in a fasting animal model"],"prefix":"10.1016","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7005-1352","authenticated-orcid":false,"given":"Ayse","family":"Tuzlaci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2474-4541","authenticated-orcid":false,"given":"Fetiye","family":"Kolayli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6080-0673","authenticated-orcid":false,"given":"Bahar","family":"Muezzinoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8025-1747","authenticated-orcid":false,"given":"Bekir Haluk","family":"G\u00fcven\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2025.110030_bib0001","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1007\/s00268-005-0613-9","article-title":"Review of the pathophysiology and management of postoperative ileus","volume":"30","author":"Mattei","year":"2006","journal-title":"World J Surg"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0002","first-page":"1","article-title":"Nutrition delivery after emergency laparotomy in surgical ward: a retrospective cohort study","volume":"1","author":"Nurkkala","year":"2022","journal-title":"Eur J Trauma Emergency Surg"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0003","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/jhn.12930","article-title":"Early postoperative feeding following surgery for upper gastrointestinal cancer: a systematic review","volume":"35","author":"Carmichael","year":"2022","journal-title":"J Hum Nutr Diet"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0004","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41392-024-01743-1","article-title":"Microbiota-gut-brain axis and its therapeutic applications in neurodegenerative diseases","volume":"9","author":"Loh","year":"2024","journal-title":"Signal Transduct Target Ther"},{"issue":"7","key":"10.1016\/j.jnutbio.2025.110030_bib0005","article-title":"Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications","volume":"7","author":"Herbert","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"10.1016\/j.jnutbio.2025.110030_bib0006","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/j.jpedsurg.2021.07.020","article-title":"Systematic review and meta-analysis of safety and efficacy of early enteral nutrition as an isolated component of Enhanced Recovery after Surgery [ERAS] in children after bowel anastomosis surgery: pediatric ERAS and early enteral nutrition","volume":"57","author":"Behera","year":"2022","journal-title":"J Pediatr Surg"},{"issue":"2","key":"10.1016\/j.jnutbio.2025.110030_bib0007","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.nut.2004.10.003","article-title":"Early enteral feeding in newborn surgical patients","volume":"21","author":"Ekingen","year":"2005","journal-title":"Nutrition"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0008","doi-asserted-by":"crossref","first-page":"392","DOI":"10.4103\/jiaps.jiaps_19_23","article-title":"Outcomes of early oral feeding compared to delayed feeding in children after elective distal bowel anastomosis","volume":"28","author":"Jayakumar","year":"2023","journal-title":"J Indian Assoc Pediatr Surg"},{"issue":"9","key":"10.1016\/j.jnutbio.2025.110030_bib0009","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.jpedsurg.2021.02.067","article-title":"Early enteral feeding versus traditional feeding in neonatal congenital gastrointestinal malformation undergoing intestinal anastomosis: a randomized multicenter controlled trial of an enhanced recovery after surgery (ERAS) component","volume":"56","author":"Peng","year":"2021","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0010","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/1764242","article-title":"Benefits of early enteral feeding with a locally prepared protein-energy ration after surgery for acute generalised peritonitis: a randomised trial in two hospitals in Bukavu, Eastern Democratic Republic of Congo","volume":"2023","author":"Cikwanine","year":"2023","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0011","article-title":"Ketorolac administration after colorectal surgery increases anastomotic leak rate: a meta-analysis and systematic review","volume":"9","author":"Chen","year":"2022","journal-title":"Front Surg"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e15551","article-title":"Modulation of redox-sensitive transcription factors with polyphenols as pathogenetically grounded approach in therapy of systemic inflammatory response","volume":"9","author":"Kostenko","year":"2023","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0013","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13741-021-00179-3","article-title":"Early oral protein-containing diets following elective lower gastrointestinal tract surgery in adults: a meta-analysis of randomized clinical trials","volume":"10","author":"Pu","year":"2021","journal-title":"Perioper Med (Lond)"},{"issue":"13","key":"10.1016\/j.jnutbio.2025.110030_bib0014","doi-asserted-by":"crossref","first-page":"8251","DOI":"10.1245\/s10434-023-14139-2","article-title":"Effect of early versus late oral feeding on postoperative complications and recovery outcomes for patients with esophageal cancer: a systematic evaluation and meta-analysis","volume":"30","author":"Hong","year":"2023","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.jnutbio.2025.110030_bib0015","article-title":"The outcome of early oral feeding following elective gastrointestinal surgery","volume":"16","author":"Mahmud","year":"2024","journal-title":"Cureus"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0016","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.clnu.2019.06.022","article-title":"Malnourished children acquire nosocomial infections more often and have significantly increased length of hospital stay","volume":"39","author":"Niseteo","year":"2020","journal-title":"Clin Nutr"},{"issue":"12","key":"10.1016\/j.jnutbio.2025.110030_bib0017","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1111\/pan.14738","article-title":"A review of pediatric fasting guidelines and strategies to help children manage preoperative fasting","volume":"33","author":"Zhang","year":"2023","journal-title":"Pediatr Anesth"},{"issue":"3","key":"10.1016\/j.jnutbio.2025.110030_bib0018","doi-asserted-by":"crossref","first-page":"932","DOI":"10.3390\/nu13030932","article-title":"Enteral nutrition in term infants with congenital heart disease: knowledge gaps and future directions to improve clinical practice","volume":"13","author":"Martini","year":"2021","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0019","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s10237-023-01758-7","article-title":"Association between jejunal remodeling in fasting rats and hypersensitivity of intestinal afferent nerves to mechanical stimulation","volume":"23","author":"Bao","year":"2024","journal-title":"Biomech Model Mechanobiol"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118428","article-title":"Mucosal characteristics vary across developmental stages in the small intestine of C57BL\/6J mice","volume":"260","author":"Park","year":"2020","journal-title":"Life Sci"},{"issue":"12","key":"10.1016\/j.jnutbio.2025.110030_bib0021","doi-asserted-by":"crossref","first-page":"5293","DOI":"10.1007\/s00431-023-05205-8","article-title":"Nomogram to predict feeding intolerance in critically ill children","volume":"182","author":"Lin","year":"2023","journal-title":"Eur J Pediatr"},{"issue":"4","key":"10.1016\/j.jnutbio.2025.110030_bib0022","doi-asserted-by":"crossref","first-page":"746","DOI":"10.3390\/microorganisms10040746","article-title":"Intestinal alkaline phosphatase: a review of this enzyme role in the intestinal barrier function","volume":"10","author":"Santos","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0023","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2147\/CEG.S345531","article-title":"Alkaline phosphatase pathophysiology with emphasis on the seldom-discussed role of defective elimination in unexplained elevations of serum ALP\u2013a case report and literature review","volume":"15","author":"Levitt","year":"2022","journal-title":"Clin Experiment Gastroenterol"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0024","doi-asserted-by":"crossref","first-page":"14","DOI":"10.7150\/thno.48468","article-title":"A role for intestinal alkaline phosphatase in preventing liver fibrosis","volume":"11","author":"Liu","year":"2021","journal-title":"Theranostics"},{"issue":"10","key":"10.1016\/j.jnutbio.2025.110030_bib0025","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1093\/nutrit\/nuz015","article-title":"Recent advances in intestinal alkaline phosphatase, inflammation, and nutrition","volume":"77","author":"Lall\u00e8s","year":"2019","journal-title":"Nutr Rev"},{"issue":"8","key":"10.1016\/j.jnutbio.2025.110030_bib0026","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.3390\/nu13082727","article-title":"Malnutrition and gut microbiota in children","volume":"13","author":"Iddrisu","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0027","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.846155","article-title":"Pathologic inflammation in malnutrition is driven by proinflammatory intestinal microbiota, large intestine barrier dysfunction, and translocation of bacterial lipopolysaccharide","volume":"13","author":"Patterson","year":"2022","journal-title":"Front Immunol"},{"issue":"8","key":"10.1016\/j.jnutbio.2025.110030_bib0028","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.tim.2023.02.009","article-title":"Remodelling of the intestinal ecosystem during caloric restriction and fasting","volume":"31","author":"Ducarmon","year":"2023","journal-title":"Trends Microbiol"},{"issue":"21","key":"10.1016\/j.jnutbio.2025.110030_bib0029","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.3390\/healthcare11212829","article-title":"The impact of nutritional therapy on gastrointestinal motility in older adults","volume":"11","author":"Okawa","year":"2023","journal-title":"Healthcare (Basel)"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0030","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1007\/s00068-023-02281-1","article-title":"Factors associated with the need for long-term total parenteral nutrition in survivors of acute superior mesenteric artery occlusion","volume":"49","author":"Nakao","year":"2023","journal-title":"Eur J Trauma Emerg Surg"},{"issue":"21","key":"10.1016\/j.jnutbio.2025.110030_bib0031","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.3390\/nu14214691","article-title":"Impact of total parenteral nutrition on gut microbiota in pediatric population suffering intestinal disorders","volume":"14","author":"Cerd\u00f3","year":"2022","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0032","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3390\/nu16010128","article-title":"Prolonged fasting induces histological and ultrastructural changes in the intestinal mucosa that may reduce absorption and revert after enteral refeeding","volume":"16","author":"Nunes","year":"2023","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0033","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1002\/ncp.10565","article-title":"Enteral nutrition in pediatric short-bowel syndrome","volume":"35","author":"Channabasappa","year":"2020","journal-title":"Nutr Clin Pract"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0034","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/jfb.15081","article-title":"Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth","volume":"101","author":"Wu","year":"2022","journal-title":"J Fish Biol"},{"issue":"2","key":"10.1016\/j.jnutbio.2025.110030_bib0035","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3390\/nu13020310","article-title":"Gestation food restriction and refeeding compensate maternal energy status and alleviate metabolic consequences in juvenile offspring in a rabbit model","volume":"13","author":"Garcia-Garcia","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110030_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104652","article-title":"Current progress of research on intestinal bacterial translocation","volume":"152","author":"Wang","year":"2021","journal-title":"Microb Pathog"},{"issue":"7","key":"10.1016\/j.jnutbio.2025.110030_bib0037","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.3390\/nu13072198","article-title":"The interplay between nutrition, innate immunity, and the commensal microbiota in adaptive intestinal morphogenesis","volume":"13","author":"Bayer","year":"2021","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.jnutbio.2025.110030_bib0038","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1152\/ajpregu.00270.2021","article-title":"High-altitude exposures and intestinal barrier dysfunction","volume":"322","author":"McKenna","year":"2022","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0039","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1186\/s12877-022-02981-0","article-title":"Gut microbiota alterations in critically ill older patients: a multicenter study","volume":"22","author":"Victoria","year":"2022","journal-title":"BMC Geriatr"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0040","first-page":"4","article-title":"Danger of bacterial translocation for a surgical patient","volume":"100","author":"Havel","year":"2021","journal-title":"Rozhl Chir"},{"issue":"4","key":"10.1016\/j.jnutbio.2025.110030_bib0041","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/16070658.2022.2147663","article-title":"Karstens B. Nutrition and vasoactive substances in the critically ill patient","volume":"35","author":"Spies","year":"2022","journal-title":"South African J Clin Nutr"},{"issue":"4","key":"10.1016\/j.jnutbio.2025.110030_bib0042","doi-asserted-by":"crossref","first-page":"776","DOI":"10.3906\/sag-1911-42","article-title":"Effects of oral\/enteral nutrition alone versus plus pantoprazole on gastrointestinal bleeding in critically ill patients with low risk factor: a multicenter, randomized controlled trial","volume":"50","author":"G\u00fcndo\u011fan","year":"2020","journal-title":"Turk J Med Sci"},{"issue":"2","key":"10.1016\/j.jnutbio.2025.110030_bib0043","doi-asserted-by":"crossref","first-page":"skab376","DOI":"10.1093\/jas\/skab376","article-title":"Ileal alkaline phosphatase is upregulated following functional amino acid supplementation in Salmonella Typhimurium-challenged pigs","volume":"100","author":"Rodrigues","year":"2022","journal-title":"J Anim Sci"},{"issue":"5","key":"10.1016\/j.jnutbio.2025.110030_bib0044","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1159\/000515910","article-title":"Targeting the intestinal barrier to prevent gut-derived inflammation and disease: a role for intestinal alkaline phosphatase","volume":"37","author":"K\u00fchn","year":"2021","journal-title":"Visc Med"},{"issue":"6","key":"10.1016\/j.jnutbio.2025.110030_bib0045","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.orcp.2023.09.010","article-title":"Rat models of diet-induced obesity and metabolic dysregulation: current trends, shortcomings and considerations for future research","volume":"17","author":"Sadie-Van Gijsen","year":"2023","journal-title":"Obes Res Clin Pract"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110030_bib0046","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/anae.14500","article-title":"Pre-operative fasting in adults and children: clinical practice and guidelines","volume":"74","author":"Fawcett","year":"2019","journal-title":"Anaesthesia"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001937?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325001937?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:12:22Z","timestamp":1762456342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286325001937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":46,"alternative-id":["S0955286325001937"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110030","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of the early introduction of trophic donor human breast milk on the preservation of postoperative gut functions in a fasting animal model","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110030"}}