{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:43:13Z","timestamp":1783608193525,"version":"3.55.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002402","name":"Sun Yat-sen University","doi-asserted-by":"publisher","award":["2023WW501"],"award-info":[{"award-number":["2023WW501"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012245","name":"Science and Technology Planning Project of Guangdong Province","doi-asserted-by":"publisher","award":["2023B110006"],"award-info":[{"award-number":["2023B110006"]}],"id":[{"id":"10.13039\/501100012245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82402913"],"award-info":[{"award-number":["82402913"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U22A20276"],"award-info":[{"award-number":["U22A20276"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515220097"],"award-info":[{"award-number":["2024A1515220097"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024M763811"],"award-info":[{"award-number":["2024M763811"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2025A1515012585"],"award-info":[{"award-number":["2025A1515012585"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2025A1515011990"],"award-info":[{"award-number":["2025A1515011990"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["GZC20233217"],"award-info":[{"award-number":["GZC20233217"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["2024A04J4246"],"award-info":[{"award-number":["2024A04J4246"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2025T180556"],"award-info":[{"award-number":["2025T180556"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutritional Biochemistry"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jnutbio.2025.110240","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T07:23:49Z","timestamp":1766215429000},"page":"110240","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Electroconvulsive therapy modulates brain plasticity in male depression: Links to gut microbial metabolites and diet-derived regulation of Wnt\/BDNF signaling"],"prefix":"10.1016","volume":"150","author":[{"given":"Jiaming","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijian","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenjia","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqing","family":"Hei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4736-8318","authenticated-orcid":false,"given":"Sufang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5284-9159","authenticated-orcid":false,"given":"Weifeng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5101-4101","authenticated-orcid":false,"given":"Chaojin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jnutbio.2025.110240_bib0001","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1001\/jamapsychiatry.2023.5051","article-title":"Worldwide prevalence and disability from mental disorders across childhood and adolescence: evidence from the global burden of disease study","volume":"81","author":"Kieling","year":"2024","journal-title":"JAMA Psychiatr"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0002","unstructured":"Organization WH (2017) Depression and other common mental disorders: global health estimates. Available from: https:\/\/www.who.int\/publications\/i\/item\/depression-global-health-estimates."},{"key":"10.1016\/j.jnutbio.2025.110240_bib0003","first-page":"1","article-title":"Metoprolol adverse events and literature analyses: case\/non-case analyses using the FDA Adverse Event Reporting System (FAERS)","author":"Du","year":"2024","journal-title":"Expert Opin Drug Saf"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0004","first-page":"11","article-title":"Identification of genetic variations in the NAD-related pathways for patients with major depressive disorder: A case-control study in Taiwan","author":"Chen","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0005","doi-asserted-by":"crossref","first-page":"119700","DOI":"10.1016\/j.jad.2025.119700","article-title":"Electroconvulsive therapy in adolescents and adults with depression: effects, cognitive function and related influencing factors","volume":"389","author":"Yang","year":"2025","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0006","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.brs.2021.06.011","article-title":"Biophysical mechanisms of electroconvulsive therapy-induced volume expansion in the medial temporal lobe: a longitudinal in vivo human imaging study","volume":"14","author":"Takamiya","year":"2021","journal-title":"Brain Stimul"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0007","doi-asserted-by":"crossref","first-page":"1308437","DOI":"10.3389\/fpsyt.2023.1308437","article-title":"Transcranial alternating current stimulation for schizophrenia: a systematic review of randomized controlled studies","volume":"14","author":"Wei","year":"2023","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0008","doi-asserted-by":"crossref","DOI":"10.1111\/cns.14690","article-title":"Molecular basis underlying changes of brain entropy and functional connectivity in major depressive disorders after electroconvulsive therapy","volume":"30","author":"Yu","year":"2024","journal-title":"CNS Neurosci Ther"},{"issue":"6","key":"10.1016\/j.jnutbio.2025.110240_bib0009","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.3390\/nu15061382","article-title":"A microbial-based approach to mental health: the potential of probiotics in the treatment of depression","volume":"15","author":"Johnson","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0010","doi-asserted-by":"crossref","first-page":"885393","DOI":"10.3389\/fnagi.2022.885393","article-title":"Differences in gut microbiota correlate with symptoms and regional brain volumes in patients with late-life depression","volume":"14","author":"Tsai","year":"2022","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0011","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.bbi.2023.11.016","article-title":"Probiotic Clostridium butyricum ameliorates cognitive impairment in obesity via the microbiota-gut-brain axis","volume":"115","author":"Zheng","year":"2024","journal-title":"Brain Behav Immun"},{"issue":"12","key":"10.1016\/j.jnutbio.2025.110240_bib0012","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.3390\/nu11123038","article-title":"Eating disorders and gastrointestinal diseases","volume":"11","author":"Santonicola","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0013","doi-asserted-by":"crossref","first-page":"6334868","DOI":"10.1155\/2022\/6334868","article-title":"Exploring the correlation between changes in gut microbial community diversity and depression in Human populations","volume":"2022","author":"Li","year":"2022","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0014","doi-asserted-by":"crossref","first-page":"864571","DOI":"10.3389\/fmicb.2022.864571","article-title":"Oral administration of 5-hydroxytryptophan restores gut microbiota dysbiosis in a mouse model of depression","volume":"13","author":"Wu","year":"2022","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0015","article-title":"The role of gastrointestinal dysbiosis and fecal transplantation in various neurocognitive disorders","volume":"16","author":"Castro-Vidal","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0016","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3389\/fgene.2019.00098","article-title":"Current understanding of gut microbiota in mood disorders: an update of Human studies","volume":"10","author":"Huang","year":"2019","journal-title":"Front Genet"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0017","doi-asserted-by":"crossref","first-page":"100592","DOI":"10.1016\/j.ynstr.2023.100592","article-title":"Association between gut microbiota and its functional metabolites with prenatal depression in women","volume":"28","author":"Xie","year":"2024","journal-title":"Neurobiol Stress"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0018","doi-asserted-by":"crossref","DOI":"10.3390\/cells12040657","article-title":"Mechanisms of blood-brain barrier protection by microbiota-derived short-chain fatty acids","volume":"12","author":"Fock","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0019","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1186\/s12967-024-05709-3","article-title":"Influence of the gut microbiota on immune cell interactions and cancer treatment","volume":"22","author":"Liu","year":"2024","journal-title":"J Transl Med"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0020","doi-asserted-by":"crossref","first-page":"1237237","DOI":"10.3389\/fnut.2023.1237237","article-title":"Morel (Morchella spp.) intake alters gut microbial community and short-chain fatty acid profiles in mice","volume":"10","author":"Pei","year":"2023","journal-title":"Front Nutr"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0021","doi-asserted-by":"crossref","first-page":"1289102","DOI":"10.3389\/fmicb.2023.1289102","article-title":"The signaling pathway of hypoxia inducible factor in regulating gut homeostasis","volume":"14","author":"Liu","year":"2023","journal-title":"Front Microbiol"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110240_bib0022","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3390\/toxics12010039","article-title":"Interaction between per- and polyfluorinated substances (PFAS) and acetaminophen in disease exacerbation-focusing on autism and the gut-liver-brain axis","volume":"12","author":"Jiang","year":"2024","journal-title":"Toxics"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0023","first-page":"2497430","article-title":"Electroacupuncture alleviates visceral hypersensitivity in IBS-D rats by inhibiting EGCs activity through regulating BDNF\/TrkB signaling pathway","volume":"2022","author":"Zhao","year":"2022","journal-title":"Evid Based Complement Alternat Med"},{"issue":"2","key":"10.1016\/j.jnutbio.2025.110240_bib0024","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3390\/ma16020699","article-title":"Latent potential of multifunctional selenium nanoparticles in neurological diseases and altered gut microbiota","volume":"16","author":"Ashraf","year":"2023","journal-title":"Materials (Basel)"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0025","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jad.2022.02.024","article-title":"Stressful events induce long-term gut microbiota dysbiosis and associated post-traumatic stress symptoms in healthcare workers fighting against COVID-19","volume":"303","author":"Gao","year":"2022","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0026","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s12035-023-03602-6","article-title":"Akkermansia muciniphila improves depressive-like symptoms by modulating the level of 5-HT neurotransmitters in the gut and brain of mice","volume":"61","author":"Guo","year":"2024","journal-title":"Mol Neurobiol"},{"issue":"14","key":"10.1016\/j.jnutbio.2025.110240_bib0027","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.3390\/nu15143258","article-title":"The role of gut microbiota in anxiety, Depression, and other mental disorders as well as the protective effects of dietary components","volume":"15","author":"Xiong","year":"2023","journal-title":"Nutrients"},{"issue":"15","key":"10.1016\/j.jnutbio.2025.110240_bib0028","doi-asserted-by":"crossref","first-page":"12281","DOI":"10.3390\/ijms241512281","article-title":"The role of bifidobacterium bifidum novaBBF7, bifidobacterium longum novaBLG2 and Lactobacillus paracasei TJB8 to improve mechanisms linked to neuronal cells protection against oxidative condition in a gut-brain axis model","volume":"24","author":"Ferrari","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0029","doi-asserted-by":"crossref","first-page":"101534","DOI":"10.1016\/j.redox.2020.101534","article-title":"Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway","volume":"32","author":"Jia","year":"2020","journal-title":"Redox Biol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0030","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.70605","article-title":"The Association between dietary Fiber Intake and depression among US adults: a cross-sectional study based on NHANES data from 2005 to 2020","volume":"13","author":"Lai","year":"2025","journal-title":"Food Sci Nutr"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0031","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2024.1463848","article-title":"Efficacy of bifidobacterium-related preparations on depression: the first meta-analysis","volume":"15","author":"Huang","year":"2024","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0032","doi-asserted-by":"crossref","first-page":"4847","DOI":"10.1007\/s12035-016-0032-y","article-title":"The neurobiology of depression: an integrated overview from biological theories to clinical evidence","volume":"54","author":"Ferrari","year":"2017","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0033","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1544795","article-title":"Trends in research on novel antidepressant treatments","volume":"16","author":"Zelek-Molik","year":"2025","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e33157","article-title":"Potential role of gut microbiota in major depressive disorder: a review","volume":"10","author":"Khaledi","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0035","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1177\/00912174241266646","article-title":"Association between major depressive disorder and gut microbiota dysbiosis","volume":"59","author":"Rafie Sedaghat","year":"2024","journal-title":"Int J Psychiatry Med"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0036","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3389\/fnbeh.2018.00252","article-title":"The role of the intestinal microbiome in chronic psychosocial stress-induced pathologies in male mice","volume":"12","author":"Langgartner","year":"2018","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0037","doi-asserted-by":"crossref","first-page":"114256","DOI":"10.1016\/j.bbr.2022.114256","article-title":"Intestinal epithelium aryl hydrocarbon receptor is involved in stress sensitivity and maintaining depressive symptoms","volume":"440","author":"Madison","year":"2023","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0038","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/854285","article-title":"Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders","volume":"2012","author":"Jun","year":"2012","journal-title":"Neural Plast"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0039","doi-asserted-by":"crossref","first-page":"e609","DOI":"10.1038\/tp.2015.100","article-title":"Immune and neurotrophin stimulation by electroconvulsive therapy: is some inflammation needed after all?","volume":"5","author":"van Buel","year":"2015","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0040","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1038\/s41380-025-03016-x","article-title":"Hippocampal microstructural changes following electroconvulsive therapy in severe depression","volume":"30","author":"Le Berre","year":"2025","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0041","doi-asserted-by":"crossref","DOI":"10.1097\/YCT.0000000000001139","article-title":"Electroconvulsive therapy changes peripheral blood neurotrophic and inflammatory markers in depressed patients","author":"Falhani","year":"2025","journal-title":"J ect"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0042","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1038\/s41380-025-03013-0","article-title":"Erasing \u201cbad memories\u201d: reversing aberrant synaptic plasticity as therapy for neurological and psychiatric disorders","volume":"30","author":"Shi","year":"2025","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0043","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.conb.2018.06.003","article-title":"Wnt proteins as modulators of synaptic plasticity","volume":"53","author":"McLeod","year":"2018","journal-title":"Curr Opin Neurobiol"},{"issue":"1","key":"10.1016\/j.jnutbio.2025.110240_bib0044","doi-asserted-by":"crossref","first-page":"708","DOI":"10.3390\/ijms24010708","article-title":"How are synapses born? A functional and molecular view of the role of the wnt signaling pathway","volume":"24","author":"Bonansco","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0045","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/ijnp\/pyy040","article-title":"Modulation of GSK-3\u03b2\/\u03b2-catenin signaling contributes to learning and memory impairment in a rat model of depression","volume":"21","author":"Hui","year":"2018","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0046","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.neuroscience.2025.08.009","article-title":"Molecular pathways linking the serotonin transporters (SERT) to depressive disorder: from mechanisms to treatments","volume":"584","author":"Murthy","year":"2025","journal-title":"Neuroscience"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0047","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jad.2020.12.143","article-title":"Gut microbiota dysbiosis in depressed women: the association of symptom severity and microbiota function","volume":"282","author":"Chen","year":"2021","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0048","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/s41579-025-01183-w","article-title":"Gut microbiota-derived short-chain fatty acids and their role in human health and disease","volume":"23","author":"Mukhopadhya","year":"2025","journal-title":"Nat Rev Microbiol"},{"issue":"13","key":"10.1016\/j.jnutbio.2025.110240_bib0049","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.3390\/ijms25137379","article-title":"The role of short chain fatty acids in inflammation and body health","volume":"25","author":"Du","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0050","doi-asserted-by":"crossref","first-page":"109452","DOI":"10.1016\/j.cbi.2021.109452","article-title":"Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice","volume":"341","author":"Jiang","year":"2021","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0051","doi-asserted-by":"crossref","first-page":"106034","DOI":"10.1016\/j.neuint.2025.106034","article-title":"Combined supplementation of short-chain fatty acids reduces hyperphosphorylation of tau at T181,T231 and S396 sites and improves cognitive impairment in a chemically induced AD mouse model via regulation of HDAC and Keap1","volume":"189","author":"Pu","year":"2025","journal-title":"Neurochem Int"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0052","doi-asserted-by":"crossref","first-page":"1596469","DOI":"10.3389\/fphar.2025.1596469","article-title":"Chronic administration of prebiotics and probiotics prevent pathophysiological hallmarks of Alzheimer\u2019s disease in the cortex of APP\/PS1 mice","volume":"16","author":"Sarti","year":"2025","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0053","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jad.2023.02.143","article-title":"Association analysis of gut microbiota and efficacy of SSRIs antidepressants in patients with major depressive disorder","volume":"330","author":"Gao","year":"2023","journal-title":"J Affect Disord"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0054","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s13099-025-00739-8","article-title":"H.,et al. Lactobacillus reuteri DSM 17,938 ameliorates LPS-induced depression-like and anxiety-like behaviors by modulating gut microbiota and brain metabolic function","volume":"17","author":"Mo","year":"2025","journal-title":"Gut Pathog"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0055","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00424-025-03084-6","article-title":"Probiotic Bactolac alleviates depression-like behaviors by modulating BDNF, NLRP3 and MC4R levels, reducing neuroinflammation and promoting neural repair in rat model","volume":"477","author":"I\u015f\u0131k","year":"2025","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0056","doi-asserted-by":"crossref","first-page":"7927","DOI":"10.1007\/s12035-025-04738-3","article-title":"Lactobacillus fermentum ATCC 9338 supplementation prevents depressive-like behaviors through glucocorticoid receptor and N-methyl-D-aspartate2b in chronic unpredictable mild stress mouse model","volume":"62","author":"Tiwari","year":"2025","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0057","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.bbi.2024.12.028","article-title":"Tolosa-Engu\u00eds, V.,et al. Bifidobacterium longum CECT 30763 improves depressive- and anxiety-like behavior in a social defeat mouse model through the immune and dopaminergic systems","volume":"125","author":"Tamayo","year":"2025","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0058","doi-asserted-by":"crossref","first-page":"100272","DOI":"10.1016\/j.ynstr.2020.100272","article-title":"Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression","volume":"13","author":"Bakusic","year":"2020","journal-title":"Neurobiol Stress"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0059","doi-asserted-by":"crossref","first-page":"7161","DOI":"10.2147\/DDDT.S537918","article-title":"Identification and validation of antidepressant small molecules using bioinformatics and mouse depression models","volume":"19","author":"Qiao","year":"2025","journal-title":"Drug Des Devel Ther"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0060","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/s41583-022-00631-3","article-title":"How mechanisms of stem cell polarity shape the human cerebral cortex","volume":"23","author":"Andrews","year":"2022","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jnutbio.2025.110240_bib0061","doi-asserted-by":"crossref","first-page":"123198","DOI":"10.1016\/j.lfs.2024.123198","article-title":"The organoid modeling approach to understanding the mechanisms underlying neurodegeneration: a comprehensive review","volume":"358","author":"Jalali","year":"2024","journal-title":"Life Sci"}],"container-title":["The Journal of Nutritional Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325004024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955286325004024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:23:32Z","timestamp":1778563412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955286325004024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":61,"alternative-id":["S0955286325004024"],"URL":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110240","relation":{},"ISSN":["0955-2863"],"issn-type":[{"value":"0955-2863","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Electroconvulsive therapy modulates brain plasticity in male depression: Links to gut microbial metabolites and diet-derived regulation of Wnt\/BDNF signaling","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutritional Biochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jnutbio.2025.110240","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110240"}}