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We report a case of successful catheter ablation in a 17\u2010year\u2010old male with neurally mediated syncope (NMS) of the cardioinhibitory type. The patient had dextrocardia situs inversus totalis with a mirror\u2010image reversal of the thoracic and abdominal organs. Because he experienced multiple syncope episodes despite pharmacological intervention, we performed endocardial ablation of the superior vena cava\u2013aorta ganglionated plexus. Shortly afterwards, his heart rate increased from 40 to 76 beats per minutes. 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