{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:35:55Z","timestamp":1787726155951,"version":"build-2784847793"},"reference-count":13,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral Biology and Craniofacial Research"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.jobcr.2014.08.002","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T00:54:49Z","timestamp":1409100889000},"page":"135-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Ectrodactyly-ectodermal dysplasia clefting syndrome (EEC syndrome)"],"prefix":"10.1016","volume":"4","author":[{"given":"Monika","family":"Koul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Upadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jobcr.2014.08.002_bib1","first-page":"71","article-title":"Two cases in which the skin, nails and teeth were very imperfectly developed","volume":"31","author":"Thurman","year":"1848","journal-title":"Med Chir Trans"},{"issue":"2","key":"10.1016\/j.jobcr.2014.08.002_bib2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/0976-237X.96831","article-title":"Ectrodactyly\u2013ectodermal dysplasia, cleft lip and palate (EEC syndrome)","volume":"3","author":"Marwaha","year":"2012","journal-title":"Contemp Clin Dent"},{"key":"10.1016\/j.jobcr.2014.08.002_bib3","first-page":"160","article-title":"Association of ectrodactyly\u2013ectodermal dysplasia and cleft lip and palate","volume":"120","author":"Rudigar","year":"1970","journal-title":"Am J Dischild"},{"key":"10.1016\/j.jobcr.2014.08.002_bib4","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ajmg.1320530207","article-title":"Ectodermal dysplasia: a clinical classification and a casual review","volume":"53","author":"Pinheiro","year":"1994","journal-title":"Am J Med Gent"},{"key":"10.1016\/j.jobcr.2014.08.002_bib5","unstructured":"Orphanet: EEC Syndrome. www.orpha.net\/cgi-\/oc-Exp.php."},{"issue":"6","key":"10.1016\/j.jobcr.2014.08.002_bib6","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1136\/jmg.39.6.377","article-title":"The P 63 gene in EEC and other syndrome","volume":"39","author":"Brunner","year":"2002","journal-title":"J Med Genet"},{"issue":"1","key":"10.1016\/j.jobcr.2014.08.002_bib7","first-page":"130","article-title":"Syndromic ectrodactylywith severe limb, ectodermal, urogenital and palatal defects map to chromosome 19","volume":"62","author":"O'Quinn","year":"1998","journal-title":"Am J Genet"},{"key":"10.1016\/j.jobcr.2014.08.002_bib8","series-title":"Ectrodactyly\u2013Ectodermal Dysplasia Cleft Lip\/Palate","author":"NORD","year":"2008"},{"issue":"5","key":"10.1016\/j.jobcr.2014.08.002_bib9","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1597\/1545-1569_2001_038_0504_pedrso_2.0.co_2","article-title":"Pure ectodermal dysplasia: retrospective study of 16 cases and literature review","volume":"38","author":"Ruhin","year":"2001","journal-title":"Cleft Palate Craniofac J"},{"issue":"8","key":"10.1016\/j.jobcr.2014.08.002_bib10","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1136\/jmg.39.8.559","article-title":"Analysis of the P 63 gene in classical EEC syndrome, related syndrome and non- syndromic orofacial clefts","volume":"39","author":"Barrow","year":"2002","journal-title":"J Med Genet"},{"key":"10.1016\/j.jobcr.2014.08.002_bib11","series-title":"Rapp\u2013Hodgkin Syndrome","year":"2006"},{"key":"10.1016\/j.jobcr.2014.08.002_bib12","series-title":"Hay\u2013Wells Syndrome: Overview Rare Diseases","year":"2012"},{"key":"10.1016\/j.jobcr.2014.08.002_bib13","doi-asserted-by":"crossref","unstructured":"Avitan- Hersh E, Indelman M, Bargman R, Sprecher E. ADULT syndrome caused by mutation previously associated with EEC syndrome. Niley Black well. doi: 10.1111\/5-1525-1470. 2010.01131.","DOI":"10.1111\/j.1525-1470.2010.01131.x"}],"container-title":["Journal of Oral Biology and Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212426814000360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212426814000360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:21:53Z","timestamp":1761945713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212426814000360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S2212426814000360"],"URL":"https:\/\/doi.org\/10.1016\/j.jobcr.2014.08.002","relation":{},"ISSN":["2212-4268"],"issn-type":[{"value":"2212-4268","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ectrodactyly-ectodermal dysplasia clefting syndrome (EEC syndrome)","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral Biology and Craniofacial Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jobcr.2014.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}