{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T22:26:40Z","timestamp":1789943200270,"version":"4.0.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral Biology and Craniofacial Research"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jobcr.2015.08.004","type":"journal-article","created":{"date-parts":[[2015,9,8]],"date-time":"2015-09-08T03:08:39Z","timestamp":1441681719000},"page":"S39-S43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"S1","title":["The influence of smoking on the levels of matrix metalloproteinase-8 and periodontal parameters in smoker and nonsmoker patients with chronic periodontitis: A clinicobiochemical study"],"prefix":"10.1016","volume":"6","author":[{"given":"Namita","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narinder Dev","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lata","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shagufta","family":"Moin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagar","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jobcr.2015.08.004_bib0155","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1902\/jop.2005.76.8.1406","article-title":"Position paper: epidemiology of periodontal diseases","volume":"76","author":"Burt","year":"2005","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0160","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1034\/j.1600-0765.2001.036004227.x","article-title":"Humoral immune response in early onset periodontitis: influence of smoking","volume":"36","author":"Mooney","year":"2001","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0165","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1600-051X.2010.01676.x","article-title":"Effect of nicotine, cotinine and cigarette smoke extract on the neutrophil respiratory burst","volume":"38","author":"Matthew","year":"2011","journal-title":"J Clin Periodontol"},{"issue":"suppl 6","key":"10.1016\/j.jobcr.2015.08.004_bib0170","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1600-051X.2005.00786.x","article-title":"Mechanisms of action of environmental factors \u2013 tobacco smoking","volume":"32","author":"Palmer","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0175","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1902\/jop.1994.65.5.545","article-title":"Tobacco use as a risk factor","volume":"65","author":"Bergstrom","year":"1994","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0180","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1034\/j.1600-051X.2002.290502.x","article-title":"Granulocyte elastase, matrix metalloproteinase-8 and prostaglandin E2 in gingival crevicular fluid in matched clinical sites in smokers and non-smokers with persistent periodontitis","volume":"29","author":"Soder","year":"2002","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0185","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1902\/jop.2007.070149","article-title":"GCF MMP-8 levels in smokers and non smokers with chronic periodontitis following scaling and root planing accompanied by systemic use of flurbiprofen","volume":"78","author":"Kurtis","year":"2007","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0190","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1124\/mol.105.012591","article-title":"Cigarette smoke activates human monocytes by an oxidant AP-1 signaling pathway: implications for steroid resistance","volume":"68","author":"Walters","year":"2005","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0195","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1600-0765.1990.tb01035.x","article-title":"Salivary collagenase. Origin, characteristics and relationship to periodontal health","volume":"25","author":"Uitto","year":"1990","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0200","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1902\/jop.2009.080480","article-title":"Identification of pathogen and host-response markers correlated with periodontal disease","volume":"80","author":"Ramseier","year":"2009","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0205","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1600-0765.2011.01416.x","article-title":"Full mouth profile of active MMP-8 in periodontitis patients","volume":"47","author":"Kraft","year":"2012","journal-title":"J Periodontal Res"},{"issue":"7 suppl","key":"10.1016\/j.jobcr.2015.08.004_bib0210","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1902\/jop.2007.060264","article-title":"Case definitions for use in population-based surveillance of periodontitis","volume":"78","author":"Page","year":"2007","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0215","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3109\/00016356309011240","article-title":"Periodontal disease in pregnancy. I. Prevalence and severity","volume":"21","author":"L\u00f6e","year":"1963","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0220","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition","volume":"22","author":"Silness","year":"1964","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0225","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1749-6632.1993.tb18343.x","article-title":"Method for collecting saliva","volume":"694","author":"Navazesh","year":"1993","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0230","first-page":"775","article-title":"Increased local matrix metalloproteinase-8 expression in the periodontal connective tissues of smokers with periodontal disease","volume":"1762","author":"Liu","year":"2006","journal-title":"Biochem Biophys Acta"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0235","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/000163599428940","article-title":"Neutrophil elastase activity, levels of prostaglandin E2 and matrixmetalloproteinase-8 in refractory periodontitis in smokers and non smokers","volume":"57","author":"Soder","year":"1999","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0240","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1902\/jop.1999.70.11.1361","article-title":"The association between smoking cessation and periodontal status and salivary proteinase levels","volume":"70","author":"Liede","year":"1999","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0245","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1902\/jop.1993.64.1.16","article-title":"Evidence for cigarette smoking as a major risk factor for periodontitis","volume":"64","author":"Haber","year":"1993","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0250","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1902\/jop.1994.65.3.260","article-title":"Assessment of risk for periodontal disease. I. Risk indicators for attachment loss","volume":"65","author":"Grossi","year":"1994","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0255","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1034\/j.1600-051X.2002.290815.x","article-title":"Effect of smoking on periodontal tissues","volume":"29","author":"Calsina","year":"2002","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0260","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1902\/jop.1994.65.7.718","article-title":"Cigarette smoking and periodontal destruction in young adults","volume":"65","author":"Linden","year":"1994","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0265","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1034\/j.1600-051x.2001.028004283.x","article-title":"Relationship of cigarette smoking to attachment profiles","volume":"28","author":"Haffajee","year":"2001","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0270","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1902\/jop.1995.66.1.23","article-title":"Assessment of risk for periodontal disease II. Risk indicators for alveolar bone loss","volume":"66","author":"Grossi","year":"1995","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0275","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/sj.bdj.4800721","article-title":"Tobacco and oral disease EU-Working Group on Tobacco and Oral Health","volume":"189","author":"Johnson","year":"2000","journal-title":"Br Dent J"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0280","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1034\/j.1600-0757.2002.290109.x","article-title":"Global risk factors and risk indicators for periodontal disease","volume":"29","author":"Albandar","year":"2002","journal-title":"Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0285","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1034\/j.1600-051x.2000.027001061.x","article-title":"Exposure to tobacco smoking and periodontal health","volume":"27","author":"Bergstrom","year":"2000","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0290","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1902\/jop.2000.71.3.433","article-title":"Effect of smoking on periodontal health in molar teeth","volume":"71","author":"Kerdvongbundit","year":"2000","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0295","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1902\/jop.1983.54.8.481","article-title":"Association between smoking different tobacco products and periodontal disease indexes","volume":"54","author":"Feldman","year":"1983","journal-title":"J Periodontol"},{"key":"10.1016\/j.jobcr.2015.08.004_bib0300","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-051X.1990.tb01080.x","article-title":"Effect of cigarette smoking on the transition dynamics in experimental gingivitis","volume":"17","author":"Danielsen","year":"1990","journal-title":"J Clin Periodontol"}],"container-title":["Journal of Oral Biology and Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212426815000871?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212426815000871?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:23:54Z","timestamp":1761945834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212426815000871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":30,"alternative-id":["S2212426815000871"],"URL":"https:\/\/doi.org\/10.1016\/j.jobcr.2015.08.004","relation":{},"ISSN":["2212-4268"],"issn-type":[{"value":"2212-4268","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The influence of smoking on the levels of matrix metalloproteinase-8 and periodontal parameters in smoker and nonsmoker patients with chronic periodontitis: A clinicobiochemical study","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral Biology and Craniofacial Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jobcr.2015.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016","name":"copyright","label":"Copyright"}]}}