{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:26:56Z","timestamp":1790940416730,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":3609,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1016\/j.joca.2004.01.001","type":"journal-article","created":{"date-parts":[[2004,2,28]],"date-time":"2004-02-28T05:31:43Z","timestamp":1077946303000},"page":"277-283","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Hyaluronic acid levels may have predictive value for the progression of knee osteoarthritis"],"prefix":"10.1016","volume":"12","author":[{"given":"K.","family":"Pavelka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0160.","family":"Forejtov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Olej\u00e1rov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Gatterov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"\u0160enolt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"\u0160pa\u010dek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hulejov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"\u0160tov\u0131\u0301\u010dkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pavelkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2004.01.001_BIB1","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/1529-0131(199805)41:5<778::AID-ART4>3.0.CO;2-V","article-title":"Estimates of the prevalence of arthritis and selected musculosceletal disorders in the United States","volume":"41","author":"Lawrence","year":"1998","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB2","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/art.1780340502","article-title":"The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip","volume":"34","author":"Altman","year":"1991","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB3","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","article-title":"Development of criteria for the classification of osteoarthritis of the knee","volume":"29","author":"Altman","year":"1986","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB4","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/art.1780331101","article-title":"The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand","volume":"33","author":"Altman","year":"1990","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S1063-4584(05)80101-3","article-title":"Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society","volume":"4","author":"Altman","year":"1996","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB6","first-page":"799","article-title":"Recommendations for a core set of outcome measures for future phaseIII. Clinical trials in the knee, hip and hand osteoarthritis. Consensus development at OMERACT III","volume":"24","author":"Bellamy","year":"1997","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB7","first-page":"768","article-title":"Osteoarthritis clinical trials: candidates\u2019 variables and demimetric properties","volume":"24","author":"Bellamy","year":"1997","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB8","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2214\/ajr.170.3.9490936","article-title":"In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with MR imaging","volume":"170","author":"Eckstein","year":"1998","journal-title":"AJR"},{"issue":"Suppl. 5","key":"10.1016\/j.joca.2004.01.001_BIB9","first-page":"385","article-title":"X-ray technologist reproducibility in radiography of osteoarthritisknees for a multicenter clinical trial","volume":"44","author":"Buckland-Wright","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB10","first-page":"2664","article-title":"Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: a comparative radiographic study, without fluoroscopy, of standing extended, semiflexed AP and schuss views","volume":"26","author":"Buckland-Wright","year":"1999","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB11","first-page":"1308","article-title":"Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis?","volume":"29","author":"Brandt","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1053\/joca.2000.0387","article-title":"Recommendations for the registration of drugs used in the treatment of osteoarthritis: an update on biochemical markers","volume":"9","author":"Vignon","year":"2001","journal-title":"Osteoarthritis Cart"},{"issue":"12","key":"10.1016\/j.joca.2004.01.001_BIB13","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1081\/JLC-120005875","article-title":"HPLC method for pentosidine determination in urine, serum and tissues as a marker of glycation and oxidation loading of the organism","volume":"25","author":"\u0160pa\u010dek","year":"2002","journal-title":"J Liquid Chrom (Rel Technol"},{"key":"10.1016\/j.joca.2004.01.001_BIB14","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/art.1780360207","article-title":"Metalloproteinases tissue inhibitor and proteoglycan fragments in knee synovial fluid in human osteoarthritis","volume":"36","author":"Lohmander","year":"1993","journal-title":"Arthritis Rheum"},{"issue":"6","key":"10.1016\/j.joca.2004.01.001_BIB15","first-page":"294","article-title":"Quantifikation Nachweis Keratansulphat-spezifischer Epitope im Synovialpunktat bei entz\u00fcdlichen und degenerativen Gelenkerkrankungen","volume":"48","author":"Pavelka","year":"1989","journal-title":"Z Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB16","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1002\/1529-0131(199911)42:11<2356::AID-ANR14>3.0.CO;2-R","article-title":"Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: The Johnston County osteoarthritis project","volume":"42","author":"Clark","year":"1999","journal-title":"Arthritis Rheum"},{"issue":"Suppl.","key":"10.1016\/j.joca.2004.01.001_BIB17","first-page":"258","article-title":"Urinary type II collagen neoepitope in osteoarthritis is associated with disease activity","volume":"42","author":"Woodworth","year":"1999","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB18","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3109\/07853899609033126","article-title":"Serum hyaluronan as a disease marker","volume":"28","author":"Laurent","year":"1995","journal-title":"Ann Med"},{"key":"10.1016\/j.joca.2004.01.001_BIB19","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/art.1780400419","article-title":"Low levels increases in serum C reactive protein are present in early osteoarthritis of the knee and predict progressive disease","volume":"40","author":"Spector","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB20","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/rheumatology\/35.6.553","article-title":"Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee point","volume":"35","author":"Johansen","year":"1996","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB21","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/rheumatology\/38.6.510","article-title":"Measurement of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase-l (TIMP-l) in patients with generalised osteoarthritis","volume":"38","author":"Naito","year":"1999","journal-title":"Rheumatology"},{"key":"10.1016\/j.joca.2004.01.001_BIB22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/rheumatology\/33.1.11","article-title":"Urinary excretion of pyridinoline crosslinks of collagen correlated with point damage in arthritis","volume":"33","author":"Astbury","year":"1994","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB23","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/ard.57.9.527","article-title":"Serum concentrations of cartilage olimeric matrix protein and bone sialoprotein in hip OA. A one-year study","volume":"9","author":"Conrozier","year":"1998","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2004.01.001_BIB24","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1002\/art.1780380608","article-title":"Serum hyaluronic acid level as a predictor of disease progression in osteoarthritis of the knee","volume":"38","author":"Sharif","year":"1995","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB25","first-page":"759","article-title":"Increase of C reactive protein levels by immunonephelometry in patients with rapidly destructive hip OA","volume":"12","author":"Conrozier","year":"1998","journal-title":"Rev Rhum (Engl edn)"},{"key":"10.1016\/j.joca.2004.01.001_BIB26","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1053\/joca.2000.0389","article-title":"Tissue inhibitor of metalloprotease-1 (TIMP-l) serum level may predict progression of the hip osteoarthritis","volume":"9","author":"Chavalier","year":"2001","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB27","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1053\/joca.1999.0307","article-title":"A 5-year randomized controlled, double-blind study of glycosaminoglycan polysulphuric acid complex (Rumalon) as a structure modifying therapy in osteoarthritis of the hip and knee","volume":"8","author":"Pavelka","year":"2000","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB28","first-page":"155","article-title":"Chondrometry quantitative evaluation of point space width and rate of joint space loss in osteoarthritis of the hip","volume":"62","author":"Lequesne","year":"1995","journal-title":"Rev Rhum (Engl edn)"},{"key":"10.1016\/j.joca.2004.01.001_BIB29","first-page":"473","article-title":"Radiographic progression of knee osteoarthritis in a Czech cohort","volume":"18","author":"Pavelka","year":"2000","journal-title":"Clin Exp Rheum"},{"issue":"Suppl. A","key":"10.1016\/j.joca.2004.01.001_BIB30","first-page":"3","article-title":"Atlas of individual radiographic features in osteoarthritis","volume":"3","author":"Altman","year":"1996","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB31","first-page":"1","volume":"8019","author":"Vil\u0131\u0301m","year":"2002","journal-title":"Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA Clin Chim Acta"},{"key":"10.1016\/j.joca.2004.01.001_BIB32","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S1063-4584(97)80017-9","article-title":"Is conventional radiography suitable for evaluation of a disease \u2013 modifying drugs in patients with knee osteoarthritis?","volume":"5","author":"Mazzuca","year":"1997","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB33","first-page":"1308","article-title":"Which is the best radiographic protocol for a clinical trial of a structure-modifying drug in patients with knee osteoarthritis?","volume":"29","author":"Brandt","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2004.01.001_BIB34","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0168-9525(90)90126-Q","article-title":"Metalloproteinases and their inhibitors in matrix remodelling","volume":"4","author":"Matrisian","year":"1990","journal-title":"TIG"},{"key":"10.1016\/j.joca.2004.01.001_BIB35","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3181\/00379727-218-44264","article-title":"Nonenzymatic glycation of collagen in aging and diabetes","volume":"218","author":"Reiser","year":"1998","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1016\/j.joca.2004.01.001_BIB36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0047-6374(98)00119-5","article-title":"Mechanism of maturation and aging of collagen","volume":"106","author":"Bailey","year":"1998","journal-title":"Mech Ageing Dev"},{"key":"10.1016\/j.joca.2004.01.001_BIB37","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1046\/j.1523-1755.1998.00756.x","article-title":"Renal catabolism of advanced glycation end products the fate of pentosidine","volume":"53","author":"Miyata","year":"1998","journal-title":"Kidney Int"},{"key":"10.1016\/j.joca.2004.01.001_BIB38","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1006\/bbrc.1998.8203","article-title":"Increased pentosidine, an advanced glycation end products, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers","volume":"266","author":"Miyata","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.joca.2004.01.001_BIB39","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1053\/joca.2001.0469","article-title":"Accumulation of advanced glycation end products reduces chondrocyte \u2013 mediated extracellular matrix turnover in human articular cartilage","volume":"9","author":"De Groot","year":"2001","journal-title":"Osteoarthritis Cart"},{"key":"10.1016\/j.joca.2004.01.001_BIB40","article-title":"Pentosidine in osteoarthritis: HPLC determination in body fluids and in tissues","author":"\u0160pacek","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2004.01.001_BIB41","unstructured":"\u0160enolt L, Vil\u0131\u0301m V, Braun M, \u0160pa\u010dek P, Pavelka K. Pentosidine, well-characterized advanced glycation and product, in serum and synovial fluid in patients with primary knee osteoarthritis (Abstract Lisbon). Ann Rheum Dis 2003;129."}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458404000044?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458404000044?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:04:17Z","timestamp":1761015857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458404000044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S1063458404000044"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2004.01.001","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2004,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hyaluronic acid levels may have predictive value for the progression of knee osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2004.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}