{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:50:26Z","timestamp":1789908626879,"version":"4.0.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":2849,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.joca.2005.11.012","type":"journal-article","created":{"date-parts":[[2006,1,27]],"date-time":"2006-01-27T09:55:03Z","timestamp":1138355703000},"page":"413-417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["High signal in knee osteophytes is not associated with knee pain"],"prefix":"10.1016","volume":"14","author":[{"given":"M.","family":"Sengupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.Q.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.B.","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Guermazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Grigorian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Gale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.T.","family":"Felson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.J.","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.joca.2005.11.012_bib1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/rheumatology\/31.3.189","article-title":"Knee pain and disability in the community","volume":"31","author":"McAlindon","year":"1992","journal-title":"Br J Rheumatol"},{"issue":"6","key":"10.1016\/j.joca.2005.11.012_bib2","first-page":"1031","article-title":"Pain mechanisms in osteoarthritis of the knee: effect of intraarticular anesthetic","volume":"23","author":"Creamer","year":"1996","journal-title":"J Rheumatol"},{"issue":"5","key":"10.1016\/j.joca.2005.11.012_bib3","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1053\/joca.1998.0130","article-title":"Where does it hurt? Pain localization in osteoarthritis of the knee","volume":"6","author":"Creamer","year":"1998","journal-title":"Osteoarthritis Cartilage"},{"issue":"11","key":"10.1016\/j.joca.2005.11.012_bib4","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1136\/ard.52.11.790","article-title":"Definition of osteoarthritis of the knee for epidemiological studies","volume":"52","author":"Spector","year":"1993","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.joca.2005.11.012_bib5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1063-4584(05)80323-1","article-title":"Association of pain with radiological changes in different compartments and views of the knee joint","volume":"4","author":"Cicuttini","year":"1996","journal-title":"Osteoarthritis Cartilage"},{"issue":"1","key":"10.1016\/j.joca.2005.11.012_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/ard.50.1.14","article-title":"Magnetic resonance imaging in osteoarthritis of the knee: correlation with radiographic and scintigraphic findings","volume":"50","author":"McAlindon","year":"1991","journal-title":"Ann Rheum Dis"},{"issue":"7","key":"10.1016\/j.joca.2005.11.012_bib7","doi-asserted-by":"crossref","first-page":"541","DOI":"10.7326\/0003-4819-134-7-200104030-00007","article-title":"The association of bone marrow lesions with pain in knee osteoarthritis","volume":"134","author":"Felson","year":"2001","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.joca.2005.11.012_bib8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.joca.2003.11.003","article-title":"Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis","volume":"12","author":"Peterfy","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"issue":"12","key":"10.1016\/j.joca.2005.11.012_bib9","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee","volume":"15","author":"Bellamy","year":"1988","journal-title":"J Rheumatol"},{"issue":"5","key":"10.1016\/j.joca.2005.11.012_bib10","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.joca.2004.02.001","article-title":"OMERACT-OARSI Initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited","volume":"12","author":"Pham","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2005.11.012_bib11","first-page":"1","article-title":"Roles of articular cartilage aging and chondrocyte senescence in the pathogenesis of osteoarthritis","volume":"21","author":"Martin","year":"2001","journal-title":"Iowa Orthop J"},{"issue":"1","key":"10.1016\/j.joca.2005.11.012_bib12","doi-asserted-by":"crossref","first-page":"4","DOI":"10.2106\/00004623-200301000-00002","article-title":"The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee","volume":"85-A","author":"Bhattacharyya","year":"2003","journal-title":"J Bone Joint Surg Am"},{"issue":"5 Pt 1","key":"10.1016\/j.joca.2005.11.012_bib13","doi-asserted-by":"crossref","first-page":"330","DOI":"10.7326\/0003-4819-139-5_Part_1-200309020-00008","article-title":"Bone marrow edema and its relation to progression of knee osteoarthritis","volume":"139","author":"Felson","year":"2003","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.joca.2005.11.012_bib14","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1053\/joca.1999.0256","article-title":"Meniscal subluxation: association with osteoarthritis and joint space narrowing","volume":"7","author":"Gale","year":"1999","journal-title":"Osteoarthritis Cartilage"},{"issue":"6","key":"10.1016\/j.joca.2005.11.012_bib15","first-page":"1330","article-title":"Knee effusions, popliteal cysts, and synovial thickening: association with knee pain in osteoarthritis","volume":"28","author":"Hill","year":"2001","journal-title":"J Rheumatol"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458405003262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458405003262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:11:01Z","timestamp":1761016261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458405003262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S1063458405003262"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2005.11.012","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High signal in knee osteophytes is not associated with knee pain","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2005.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}