{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:31:14Z","timestamp":1789810274352,"version":"4.0.1"},"reference-count":62,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":2573,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.joca.2006.06.020","type":"journal-article","created":{"date-parts":[[2006,8,15]],"date-time":"2006-08-15T08:27:48Z","timestamp":1155630468000},"page":"179-186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis"],"prefix":"10.1016","volume":"15","author":[{"given":"E.A.","family":"Messent","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.J.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.J.","family":"Tonkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Buckland-Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2006.06.020_bib1","series-title":"Diagnosis of Bone and Joint Disorders","article-title":"Degenerative disease in extraspinal locations","author":"Resnick","year":"1995"},{"key":"10.1016\/j.joca.2006.06.020_bib2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3109\/17453677308988675","article-title":"The relationship between osteophytes in the knee joint, osteoarthritis and aging","volume":"44","author":"Hernborg","year":"1973","journal-title":"Acta Orthop Scand"},{"key":"10.1016\/j.joca.2006.06.020_bib3","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1136\/ard.50.9.627","article-title":"Osteophytes in the osteoarthritic hand: their incidence, size, distribution, and progression","volume":"50","author":"Buckland-Wright","year":"1991","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/art.1780330107","article-title":"Quantitative microfocal radiographic assessment of progression in osteoarthritis of the hand","volume":"33","author":"Buckland-Wright","year":"1990","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2006.06.020_bib5","first-page":"3","article-title":"Atlas of individual radiographic features in osteoarthritis","volume":"3","author":"Altman","year":"1995","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/rheumatology\/keh344","article-title":"Osteoarthritis, angiogenesis and inflammation","volume":"44","author":"Bonnet","year":"2005","journal-title":"Rheumatology"},{"key":"10.1016\/j.joca.2006.06.020_bib7","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1053\/joca.2001.0505","article-title":"Development and regulation of osteophyte formation during experimental osteoarthritis","volume":"10","author":"Hashimoto","year":"2002","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib8","first-page":"311","article-title":"Studies of osteophyte pathogenesis in experimentally induced osteoarthritis","volume":"14","author":"Moskowitz","year":"1987","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2006.06.020_bib9","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/BF00177678","article-title":"Technetium 99m methylene diphosphonate bone scanning in osteoarthritic hands","volume":"18","author":"Buckland-Wright","year":"1991","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.joca.2006.06.020_bib10","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/ard.50.9.623","article-title":"Comparison of clinical, radionuclide and radiographic features of osteoarthritis of the hands","volume":"50","author":"Macfarlane","year":"1991","journal-title":"Ann Rheum Dis"},{"issue":"B","key":"10.1016\/j.joca.2006.06.020_bib11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1302\/0301-620X.35B3.442","article-title":"The normal vascular anatomy of the femoral head in adult man","volume":"35","author":"Trueta","year":"1953","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.joca.2006.06.020_bib12","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/BF02272149","article-title":"Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma","volume":"28","author":"Walsh","year":"1996","journal-title":"Histochem J"},{"key":"10.1016\/j.joca.2006.06.020_bib13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1063-4584(05)80323-1","article-title":"Association of pain with radiological changes in different compartments and views of the knee joint","volume":"4","author":"Cicuttini","year":"1996","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib14","unstructured":"Lo GH, Zhang Y, LaValley MP, Niu J, Clancy M, Goggins J, et\u00a0al. Enlarging Bone Marrow Lesions Predict Enlarging Osteophytes. In: Conference Proceeding, Abstract no: 89, American College Rheumatology, San Diego 2005."},{"key":"10.1016\/j.joca.2006.06.020_bib15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.joca.2004.10.009","article-title":"Cancellous bone differences between knees with early, definite and advanced joint space loss; a comparative quantitative macroradiographic study","volume":"13","author":"Messent","year":"2005","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib16","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.joca.2005.01.007","article-title":"Tibial cancellous bone changes in patients with knee osteoarthritis. A short-term longitudinal study using Fractal Signature Analysis","volume":"13","author":"Messent","year":"2005","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib17","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/BF02555898","article-title":"Subchondral bone in osteoarthritis","volume":"49","author":"Grynpas","year":"1991","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.joca.2006.06.020_bib18","first-page":"2187","article-title":"Periarticular osteoporosis in osteoarthritis of the knee","volume":"25","author":"Karvonen","year":"1998","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2006.06.020_bib19","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","article-title":"Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee","volume":"29","author":"Altman","year":"1986","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2006.06.020_bib20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1259\/0007-1285-62-735-201","article-title":"A new high-definition microfocal X-ray unit","volume":"62","author":"Buckland-Wright","year":"1989","journal-title":"Br J Radiol"},{"key":"10.1016\/j.joca.2006.06.020_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1259\/0007-1285-62-735-209","article-title":"Clinical applications of high-definition microfocal radiography","volume":"62","author":"Buckland-Wright","year":"1989","journal-title":"Br J Radiol"},{"key":"10.1016\/j.joca.2006.06.020_bib22","first-page":"S71","article-title":"Protocols for precise radio-anatomical positioning of the tibiofemoral and patellofemoral compartments of the knee","author":"Buckland-Wright","year":"1995","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib23","unstructured":"Ward RJ. Assessment of radiographic tibio-femoral joint space width measurements: reproducibility and practicability for clinical trials in osteoarthritis. PhD thesis, 2004, University of London."},{"key":"10.1016\/j.joca.2006.06.020_bib24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"key":"10.1016\/j.joca.2006.06.020_bib25","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1088\/0031-9155\/36\/6\/001","article-title":"Analysis of texture in macroradiographs of osteoarthritic knees using the fractal signature","volume":"36","author":"Lynch","year":"1991","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.joca.2006.06.020_bib26","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3109\/14639239109012130","article-title":"A robust and accurate method for calculating the fractal signature of texture in macroradiographs of osteoarthritic knees","volume":"16","author":"Lynch","year":"1991","journal-title":"Med Inform"},{"key":"10.1016\/j.joca.2006.06.020_bib27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0030-4220(92)90222-C","article-title":"Fractal dimension from radiographs of peridental alveolar bone. A possible diagnostic indicator of osteoporosis","volume":"74","author":"Ruttimann","year":"1992","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joca.2006.06.020_bib28","first-page":"168","article-title":"The fractal dimension of trabecular bone: a measure of trabecular structure","volume":"52","author":"Majumdar","year":"1993","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.joca.2006.06.020_bib29","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1109\/TMI.1986.4307764","article-title":"Fractional Brownian-motion: a maximum likelihood estimator and its application to imaging texture","volume":"5","author":"Lundahl","year":"1986","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.joca.2006.06.020_bib30","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1109\/TPAMI.1984.4767591","article-title":"Fractal-based descriptions of natural scenes","volume":"6","author":"Pentland","year":"1984","journal-title":"IEEE Trans Pattern Analysis Machine Intelligence"},{"key":"10.1016\/j.joca.2006.06.020_bib31","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1359\/jbmr.2000.15.4.691","article-title":"Fractal dimension of trabecular bone projection texture is related to three-dimensional microarchitecture","volume":"15","author":"Pothuaud","year":"2000","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.joca.2006.06.020_bib32","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s001980050156","article-title":"Relationship between plain radiographic patterns and three-dimensional trabecular architecture in the human calcaneus","volume":"9","author":"Luo","year":"1999","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.joca.2006.06.020_bib33","first-page":"714","article-title":"Changes in anisotropy of modelled bone measured by simulated radiography and fractal signature analysis","volume":"21","author":"Lynch","year":"1996","journal-title":"Trans Orthop Res Soc"},{"key":"10.1016\/j.joca.2006.06.020_bib34","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/ard.55.10.749","article-title":"Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis","volume":"55","author":"Buckland-Wright","year":"1996","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/8756-3282(95)00137-3","article-title":"Trabecular microstructure in the medial condyle of the proximal tibia of patients with knee osteoarthritis","volume":"17","author":"Kamibayashi","year":"1995","journal-title":"Bone"},{"key":"10.1016\/j.joca.2006.06.020_bib36","unstructured":"Ding M, Odgaard A, Danielsen CC, Hvid I. Deterioration in the quality of tibial cancellous bone in early stage human osteoarthritis. In: 47th Annual Meeting. Orthopaedic Research Society 2001."},{"key":"10.1016\/j.joca.2006.06.020_bib37","first-page":"1734","article-title":"Quantitative microfocal radiographic assessment of osteoarthritis of the knee from weight bearing tunnel and semiflexed standing views","volume":"21","author":"Buckland-Wright","year":"1994","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.joca.2006.06.020_bib38","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/BF00296060","article-title":"Fractal signature analysis of macroradiographs measures trabecular organization in lumbar vertebrae of postmenopausal women","volume":"54","author":"Buckland-Wright","year":"1994","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.joca.2006.06.020_bib39","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S8756-3282(01)00493-8","article-title":"Fractal dimension analysis of weight-bearing bones of rats during skeletal unloading","volume":"29","author":"Pornprasertsuk","year":"2001","journal-title":"Bone"},{"key":"10.1016\/j.joca.2006.06.020_bib40","unstructured":"Messent EA. Quantitative radiographic assessment of tibial cancellous bone changes in knee osteoarthritis. PhD thesis, 2004, University of London."},{"key":"10.1016\/j.joca.2006.06.020_bib41","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.joca.2003.09.007","article-title":"Subchondral bone changes in hand and knee osteoarthritis detected by radiography","volume":"12","author":"Buckland-Wright","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib42","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1002\/art.1780361019","article-title":"A longitudinal study of subchondral plate and trabecular bone in cruciate- deficient dogs with osteoarthritis followed up for 54 months","volume":"36","author":"Dedrick","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2006.06.020_bib43","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.joca.2004.09.001","article-title":"A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee","volume":"12","author":"Blumentkrantz","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib44","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1136\/ard.2004.029082","article-title":"Tibial plateau size is related to grade of joint space narrowing and osteophytes in healthy women and in women with osteoarthritis","volume":"64","author":"Wluka","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib45","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.joca.2003.08.010","article-title":"Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females","volume":"12","author":"Jones","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib46","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/jor.1100170410","article-title":"Reduced bone stress as predicted by composite beam theory correlates with cortical bone loss following cemented total hip arthroplasty","volume":"17","author":"Silva","year":"1999","journal-title":"J Orthop Res"},{"key":"10.1016\/j.joca.2006.06.020_bib47","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/jor.1100140515","article-title":"Calculated stress-shielding in the distal femur after total knee replacement corresponds to the reported location of bone loss","volume":"14","author":"Tissakht","year":"1996","journal-title":"J Orthop Res"},{"key":"10.1016\/j.joca.2006.06.020_bib48","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S1063-4584(97)80020-9","article-title":"Defining radiographic osteoarthritis for the whole knee","volume":"5","author":"Felson","year":"1997","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib49","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1063-4584(97)80002-7","article-title":"The Bristol \u2018OA500\u2019 Study: Progression of osteoarthritis (OA) over 3 years and the relationship between clinical and radiographic changes at the knee joint","volume":"5","author":"Dieppe","year":"1997","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2006.06.020_bib50","first-page":"S14","article-title":"Sensitivity of radiographic features and specificity of scintigraphic imaging in hand osteoarthritis","volume":"62","author":"Buckland-Wright","year":"1995","journal-title":"Revue du Rhumatisme (English Edition)"},{"key":"10.1016\/j.joca.2006.06.020_bib51","first-page":"139","article-title":"The longterm outcome of osteoarthritis: Rates and predictors of joint space narrowing in symptomatic patients with knee osteoarthritis","volume":"29","author":"Wolfe","year":"2002","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.joca.2006.06.020_bib52","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1359\/jbmr.1997.12.4.641","article-title":"Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis","volume":"12","author":"Li","year":"1997","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.joca.2006.06.020_bib53","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00003086-198612000-00005","article-title":"Role of subchondral bone in the initiation and progression of cartilage damage","volume":"213","author":"Radin","year":"1986","journal-title":"Clin Orthop"},{"key":"10.1016\/j.joca.2006.06.020_bib54","doi-asserted-by":"crossref","first-page":"147","DOI":"10.4314\/wajm.v24i2.28186","article-title":"The ultrastructure of the peri-articular osteophytes - An evaluation by scanning electron microscopy","volume":"24","author":"Alonge","year":"2005","journal-title":"West Afr J Med"},{"key":"10.1016\/j.joca.2006.06.020_bib55","first-page":"248","article-title":"Changes in the articular compartment in advanced osteoarthritis","volume":"70","author":"Hulejova","year":"2003","journal-title":"Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca"},{"key":"10.1016\/j.joca.2006.06.020_bib56","first-page":"2381","article-title":"High resolution ultrasonography in detection of bone erosions in patients with hand osteoarthritis","volume":"32","author":"Iagnocco","year":"2005","journal-title":"J Rheumatol"},{"key":"10.1016\/j.joca.2006.06.020_bib57","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1136\/ard.2005.037994","article-title":"EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis","volume":"64","author":"D'Agostino","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib58","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1002\/art.11094","article-title":"Inflammation and angiogenesis in osteoarthritis","volume":"48","author":"Haywood","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2006.06.020_bib59","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/ard.46.6.463","article-title":"Incidence and size of erosions in the wrist and hand of rheumatoid patients: a quantitative microfocal radiographic study","volume":"46","author":"Buckland-Wright","year":"1987","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib60","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1136\/ard.48.1.25","article-title":"Erosion number and area progression in the wrists and hands of rheumatoid patients: A quantitative microfocal radiographic study","volume":"48","author":"Buckland-Wright","year":"1989","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib61","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0307-742X(21)00545-2","article-title":"Inflammation in osteoarthritis","volume":"11","author":"Altman","year":"1985","journal-title":"Clin Rheum Dis"},{"key":"10.1016\/j.joca.2006.06.020_bib62","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1093\/rheumatology\/keh270","article-title":"Cancellous bone changes in the radius of patients with rheumatoid arthritis: A cross-sectional quantitative macroradiographic study","volume":"43","author":"Disini","year":"2004","journal-title":"Rheumatology"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458406002081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458406002081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:13:10Z","timestamp":1761016390000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458406002081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":62,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S1063458406002081"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2006.06.020","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2006.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}