{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:27:09Z","timestamp":1790940429163,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":1842,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.joca.2008.06.017","type":"journal-article","created":{"date-parts":[[2008,8,30]],"date-time":"2008-08-30T07:26:04Z","timestamp":1220081164000},"page":"188-196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Use of routine clinical multimodality imaging in a rabbit model of osteoarthritis \u2013 part I"],"prefix":"10.1016","volume":"17","author":[{"given":"M.","family":"Bouchgua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Andr\u00e9 d'Anjou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Girard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Norman","family":"Carmel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Beauchamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Richard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Laverty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2008.06.017_bib1","series-title":"Osteoarthritis","first-page":"211","article-title":"Plain radiographic features of osteoarthritis","author":"Watt","year":"2003"},{"key":"10.1016\/j.joca.2008.06.017_bib2","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1053\/joca.1998.0233","article-title":"Radiographic assessment. Introduction: existing methodology","volume":"7","author":"Rovati","year":"1999","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib3","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/00002281-200209000-00020","article-title":"Imaging of the disease process","volume":"14","author":"Peterfy","year":"2002","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.joca.2008.06.017_bib4","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.2042-3306.1987.tb02673.x","article-title":"Detection by computed tomography of occult osteochondral defects in the fetlock of a horse","volume":"19","author":"Barbee","year":"1987","journal-title":"Equine Vet J"},{"key":"10.1016\/j.joca.2008.06.017_bib5","doi-asserted-by":"crossref","first-page":"979","DOI":"10.2214\/ajr.176.4.1760979","article-title":"Musculoskeletal imaging with multislice CT","volume":"176","author":"Buckwalter","year":"2001","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.joca.2008.06.017_bib6","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.2460\/ajvr.2005.66.1487","article-title":"Effects of zoledronate on markers of bone metabolism and subchondral bone mineral density in dogs with experimentally induced cruciate-deficient osteoarthritis","volume":"66","author":"Agnello","year":"2005","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.joca.2008.06.017_bib7","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1152\/jappl.2000.89.6.2359","article-title":"Early regional adaptation of periarticular bone mineral density after anterior cruciate ligament injury","volume":"89","author":"Boyd","year":"2000","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.joca.2008.06.017_bib8","doi-asserted-by":"crossref","first-page":"796","DOI":"10.2460\/ajvr.67.5.796","article-title":"Assessment of bone mineral density of the femoral head in dogs with early osteoarthritis","volume":"67","author":"Chalmers","year":"2006","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.joca.2008.06.017_bib9","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1590\/S0100-879X2004000400006","article-title":"Radiography, computed tomography and magnetic resonance imaging at 0.5 Tesla of mechanically induced osteoarthritis in rabbit knees","volume":"37","author":"Torelli","year":"2004","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.joca.2008.06.017_bib10","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.joca.2004.03.002","article-title":"High-resolution MRI and micro-CT in an ex vivo rabbit anterior cruciate ligament transection model of osteoarthritis","volume":"12","author":"Batiste","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib11","first-page":"269","article-title":"The biochemical content of articular cartilage: an original MRI approach","volume":"39","author":"Loeuille","year":"2002","journal-title":"Biorheology"},{"key":"10.1016\/j.joca.2008.06.017_bib12","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/nbm.1102","article-title":"Sodium and T1rho MRI for molecular and diagnostic imaging of articular cartilage","volume":"19","author":"Borthakur","year":"2006","journal-title":"NMR Biomed"},{"key":"10.1016\/j.joca.2008.06.017_bib13","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/nbm.1063","article-title":"Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis","volume":"19","author":"Eckstein","year":"2006","journal-title":"NMR Biomed"},{"issue":"Suppl A","key":"10.1016\/j.joca.2008.06.017_bib14","doi-asserted-by":"crossref","first-page":"A76","DOI":"10.1016\/j.joca.2006.03.010","article-title":"MRI of articular cartilage in OA: novel pulse sequences and compositional\/functional markers","volume":"14","author":"Gold","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib15","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.joca.2003.11.003","article-title":"Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis","volume":"12","author":"Peterfy","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.7326\/0003-4819-134-7-200104030-00007","article-title":"The association of bone marrow lesions with pain in knee osteoarthritis","volume":"134","author":"Felson","year":"2001","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.joca.2008.06.017_bib17","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1002\/art.21366","article-title":"Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study","volume":"52","author":"Garnero","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2008.06.017_bib18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1740-8261.1998.tb00334.x","article-title":"Low-field magnetic resonance imaging of early subchondral cyst-like lesions in induced cranial cruciate ligament deficient dogs","volume":"39","author":"Baird","year":"1998","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.joca.2008.06.017_bib19","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/s00330-004-2486-y","article-title":"Early changes in experimental osteoarthritis using the Pond\u2013Nuki dog model: technical procedure and initial results of in vivo MR imaging","volume":"15","author":"Libicher","year":"2005","journal-title":"Eur Radiol"},{"key":"10.1016\/j.joca.2008.06.017_bib20","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1740-8261.2007.00213.x","article-title":"MRI characteristics and histology of bone marrow lesions in dogs with experimentally induced osteoarthritis","volume":"48","author":"Martig","year":"2007","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.joca.2008.06.017_bib21","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s002560050108","article-title":"MRI of degenerative bone marrow lesions in experimental osteoarthritis of canine knee joints","volume":"25","author":"Nolte-Ernsting","year":"1996","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.joca.2008.06.017_bib22","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1532-950X.2007.00363.x","article-title":"Osteophytosis, subchondral bone sclerosis, joint effusion and soft tissue thickening in canine experimental stifle osteoarthritis: comparison between 1.5T magnetic resonance imaging and computed radiography","volume":"37","author":"D'Anjou","year":"2008","journal-title":"Vet Surg"},{"key":"10.1016\/j.joca.2008.06.017_bib23","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.joca.2004.08.010","article-title":"Ex vivo characterization of articular cartilage and bone lesions in a rabbit ACL transection model of osteoarthritis using MRI and micro-CT","volume":"12","author":"Batiste","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib24","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.joca.2003.08.008","article-title":"In vivo contrast-enhanced micro MR-imaging of experimental osteoarthritis in the rabbit knee joint at 7.1T1","volume":"11","author":"Wachsmuth","year":"2003","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib25","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1053\/joca.2001.0413","article-title":"High-resolution MRI detects cartilage swelling at the early stages of experimental osteoarthritis","volume":"9","author":"Calvo","year":"2001","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib26","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/j.joca.2007.04.012","article-title":"Non-invasive in vivo quantification of the medial tibial cartilage thickness progression in an osteoarthritis rabbit model with quantitative 3D high resolution micro-MRI","volume":"15","author":"Boulocher","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib27","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.joca.2004.07.007","article-title":"Histopathological correlation of cartilage swelling detected by magnetic resonance imaging in early experimental osteoarthritis","volume":"12","author":"Calvo","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib28","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1063-4584(05)80318-8","article-title":"Characterization of a model of osteoarthritis in the rabbit knee","volume":"4","author":"Yoshioka","year":"1996","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0030-5898(20)31137-8","article-title":"Biochemical and metabolic aspects of osteoarthritis","volume":"2","author":"Mankin","year":"1971","journal-title":"Orthop Clin North Am"},{"key":"10.1016\/j.joca.2008.06.017_bib30","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1097\/00001648-199609000-00030","article-title":"How good is that agreement?","volume":"7","author":"Byrt","year":"1996","journal-title":"Epidemiology"},{"key":"10.1016\/j.joca.2008.06.017_bib31","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1053\/joca.2000.0350","article-title":"Early changes in lapine menisci during osteoarthritis development. Part I: cellular and matrix alterations","volume":"9","author":"Hellio Le Graverand","year":"2001","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib32","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/1529-0131(199901)42:1<119::AID-ANR15>3.0.CO;2-A","article-title":"High-resolution three-dimensional magnetic resonance imaging for the investigation of knee joint damage during the time course of antigen-induced arthritis in rabbits","volume":"42","author":"Dawson","year":"1999","journal-title":"Arthritis Rheum"},{"issue":"Suppl A","key":"10.1016\/j.joca.2008.06.017_bib33","doi-asserted-by":"crossref","first-page":"A95","DOI":"10.1016\/j.joca.2006.02.029","article-title":"MRI protocols for whole-organ assessment of the knee in osteoarthritis","volume":"14","author":"Peterfy","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2008.06.017_bib34","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.semarthrit.2007.01.008","article-title":"Association of bone marrow lesions with knee structures and risk factors for bone marrow lesions in the knees of clinically healthy, community-based adults","volume":"37","author":"Baranyay","year":"2007","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.joca.2008.06.017_bib35","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s002560000296","article-title":"MR imaging of the knee in marathon runners before and after competition","volume":"30","author":"Krampla","year":"2001","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.joca.2008.06.017_bib36","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s002560000316","article-title":"MRI abnormalities of foot and ankle in asymptomatic, physically active individuals","volume":"30","author":"Lohman","year":"2001","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.joca.2008.06.017_bib37","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1148\/radiology.170.3.2916038","article-title":"Occult cartilage and bone injuries of the knee: detection, classification, and assessment with MR imaging","volume":"170","author":"Mink","year":"1989","journal-title":"Radiology"},{"key":"10.1016\/j.joca.2008.06.017_bib38","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1148\/radiology.167.3.3363134","article-title":"Occult intraosseous fracture: detection with MR imaging","volume":"167","author":"Yao","year":"1988","journal-title":"Radiology"},{"key":"10.1016\/j.joca.2008.06.017_bib39","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1007\/s00330-005-0004-5","article-title":"MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptoms","volume":"16","author":"Phan","year":"2006","journal-title":"Eur Radiol"},{"key":"10.1016\/j.joca.2008.06.017_bib40","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1740-8261.1994.tb02057.x","article-title":"Radiographic and magnetic resonance imaging of the stifle joint in experimental osteoarthritis of dogs","volume":"35","author":"Widmer","year":"1994","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.joca.2008.06.017_bib41","first-page":"436","article-title":"Anterior (cranial) cruciate ligament transection in the dog: a bona fide model of osteoarthritis, not merely of cartilage injury and repair","volume":"18","author":"Brandt","year":"1991","journal-title":"J\u00a0Rheumatol"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458408002240?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458408002240?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:18:46Z","timestamp":1761016726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458408002240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S1063458408002240"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2008.06.017","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of routine clinical multimodality imaging in a rabbit model of osteoarthritis \u2013 part I","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2008.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}