{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T05:35:14Z","timestamp":1775799314182,"version":"3.50.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":412,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.joca.2012.09.009","type":"journal-article","created":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T17:20:41Z","timestamp":1348852841000},"page":"77-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["Dual inversion recovery ultrashort echo time (DIR-UTE) imaging and quantification of the zone of calcified cartilage (ZCC)"],"prefix":"10.1016","volume":"21","author":[{"given":"J.","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Carl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.C.","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Statum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.Y.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.M.","family":"Bydder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.B.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2012.09.009_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jor.1100030101","article-title":"Topographical variations in the morphology and biochemistry of adult canine tibial plateau articular cartilage","volume":"3","author":"Bullough","year":"1985","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.joca.2012.09.009_bib2","first-page":"487","article-title":"Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation","volume":"47","author":"Buckwalter","year":"1998","journal-title":"Instr Course Lect"},{"key":"10.1016\/j.joca.2012.09.009_bib3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1055\/s-2004-861764","article-title":"Cartilage MRI T2 relaxation time mapping: overview and applications","volume":"8","author":"Mosher","year":"2004","journal-title":"Semin Musculoskelet Radiol"},{"key":"10.1016\/j.joca.2012.09.009_bib4","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/nbm.1063","article-title":"Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis","volume":"19","author":"Eckstein","year":"2006","journal-title":"NMR Biomed"},{"key":"10.1016\/j.joca.2012.09.009_bib5","doi-asserted-by":"crossref","first-page":"899","DOI":"10.2214\/AJR.05.0099","article-title":"MRI of articular cartilage: revisiting current status and future directions","volume":"185","author":"Recht","year":"2005","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.joca.2012.09.009_bib6","series-title":"Methods in Cartilage Research","first-page":"322","article-title":"Fluorescent-tracer labeling for measuring remodeling in the zone of calcified cartilage","author":"Oegema","year":"1990"},{"key":"10.1016\/j.joca.2012.09.009_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1302\/0301-620X.65B1.6337169","article-title":"The morphology of the calcification front in articular cartilage","volume":"65","author":"Bullough","year":"1983","journal-title":"J\u00a0Bone Jt Surg"},{"key":"10.1016\/j.joca.2012.09.009_bib8","first-page":"271","article-title":"The calcified-non calcified cartilage interface; the tidemark","volume":"34","author":"Havelka","year":"1984","journal-title":"Acta Biol Hung"},{"key":"10.1016\/j.joca.2012.09.009_bib9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/00003086-197510000-00038","article-title":"The ultrastructure and biomechnical significance of the tidemark of articular cartilage","volume":"112","author":"Redler","year":"1975","journal-title":"Clin Orthop"},{"key":"10.1016\/j.joca.2012.09.009_bib10","first-page":"503","article-title":"On the growth and maintenance of the articular cartilage ends of adult bones","volume":"12","author":"Ogston","year":"1878","journal-title":"J\u00a0Anat Physiol"},{"key":"10.1016\/j.joca.2012.09.009_bib11","first-page":"1223","article-title":"Kinetics of osteoarthritis","volume":"3","author":"Johnson","year":"1958","journal-title":"Lab Invest"},{"key":"10.1016\/j.joca.2012.09.009_bib12","first-page":"19","article-title":"Does osteoarthritis depend on growth of the mineralized layer of cartilage?","volume":"287","author":"Hulth","year":"1993","journal-title":"Clini Orthop Relat Res"},{"key":"10.1016\/j.joca.2012.09.009_bib13","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.2214\/ajr.170.5.9574589","article-title":"MR imaging of articular cartilage of the knee: new methods using ultrashort TEs","volume":"170","author":"Gold","year":"1998","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.joca.2012.09.009_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1053\/crad.2003.1157","article-title":"Magnetic resonance imaging of short T2 components in tissues","volume":"58","author":"Gatehouse","year":"2003","journal-title":"Clin Radiol"},{"key":"10.1016\/j.joca.2012.09.009_bib15","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/mrm.21397","article-title":"Ultrashort TE spectroscopic imaging (UTESI) of cortical bone","volume":"58","author":"Du","year":"2007","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib16","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/jmri.21465","article-title":"Ultrashort TE spectroscopic imaging (UTESI): application to the imaging of short T2 relaxation tissues in the musculoskeletal system","volume":"29","author":"Du","year":"2009","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.joca.2012.09.009_bib17","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/mrm.20926","article-title":"Designing long-T2 suppression pulses for ultrashort echo time imaging","volume":"56","author":"Larson","year":"2006","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib18","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/mrm.22682","article-title":"Direct imaging and quantification of carotid plaque calcification","volume":"65","author":"Du","year":"2011","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib19","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/mrm.22257","article-title":"Dual invasion recovery UTE imaging: creating high contrast for short-T2 species","volume":"63","author":"Du","year":"2010","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib20","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1053\/joca.2002.0826","article-title":"T1\u03c1 relaxation can assess longitudinal proteoglycan loss from articular cartilage in\u00a0vitro","volume":"10","author":"Duvvuri","year":"2002","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2012.09.009_bib21","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.joca.2007.01.011","article-title":"In\u00a0vivo T1\u03c1 and T2 mapping of articular cartilage in osteoarthritis of the knee using 3T MRI","volume":"15","author":"Li","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2012.09.009_bib22","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1002\/mrm.22474","article-title":"Ultrashort TE T1rho (UTE T1rho) imaging of the Achilles tendon and meniscus","volume":"64","author":"Du","year":"2010","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib23","doi-asserted-by":"crossref","first-page":"343","DOI":"10.2214\/ajr.183.2.1830343","article-title":"Musculoskeletal MRI at 3.0T: relaxation times and image contrast","volume":"183","author":"Gold","year":"2004","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.joca.2012.09.009_bib24","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/mrm.1910400615","article-title":"Design of practical T2-selective RF excitation (TELEX) pulses","volume":"40","author":"Sussman","year":"1998","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.joca.2012.09.009_bib25","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1002\/jmri.1880070518","article-title":"Origin of cartilage laminae in MRI","volume":"7","author":"Xia","year":"1997","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.joca.2012.09.009_bib26","unstructured":"Du J, Statum S, Znamirowski R, Bydder GM, Chung CB. Ultrashort TE T1\u03c1 magic angle imaging. Magn Reson Med 2012; (Epub on-line Apr 26, 2012)."},{"key":"10.1016\/j.joca.2012.09.009_bib27","first-page":"1","article-title":"Degenerative joint disease","volume":"47","author":"Buckwalter","year":"1995","journal-title":"Clin Symp"},{"key":"10.1016\/j.joca.2012.09.009_bib28","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/00002142-199812000-00002","article-title":"Magnetic resonance imaging of articular cartilage: an overview","volume":"9","author":"Recht","year":"1998","journal-title":"Top Magn Reson Imaging"},{"key":"10.1016\/j.joca.2012.09.009_bib29","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1002\/art.21348","article-title":"Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T","volume":"52","author":"Eckstein","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2012.09.009_bib30","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/(SICI)1097-0029(19970515)37:4<324::AID-JEMT7>3.0.CO;2-K","article-title":"The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis","volume":"37","author":"Oegema","year":"1997","journal-title":"Microsc Res Tech"},{"key":"10.1016\/j.joca.2012.09.009_bib31","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1002\/jor.1100120506","article-title":"Elastic modulus of calcified cartilage is an order of magnitude less than that of subchondral bone","volume":"12","author":"Mente","year":"1994","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.joca.2012.09.009_bib32","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/00003086-199301000-00043","article-title":"The influence of basal cartilage calcification on dynamic juxtaarticular stress transmission","volume":"286","author":"Anderson","year":"1993","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.joca.2012.09.009_bib33","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.joca.2003.09.016","article-title":"Anatomy and physiology of the mineralized tissues: role in the pathogenesis of osteoarthrosis","volume":"12","author":"Burr","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2012.09.009_bib34","first-page":"191","article-title":"Nanomechanical properties and mineral concentration in articular calcified cartilage and subchondral bone","volume":"203","author":"Ferguson","year":"2003","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.joca.2012.09.009_bib35","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF02274838","article-title":"Metabolic activity in the calcified zone of cartilage: observations on tetracycline labeled articular cartilage in human osteoarthritic hips","volume":"10","author":"Revell","year":"1990","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.joca.2012.09.009_bib36","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bone.2004.03.034","article-title":"Alternations in mineral composition observed in osteoarthritic joints of cynomolgus monkeys","volume":"35","author":"Miller","year":"2004","journal-title":"Bone"},{"key":"10.1016\/j.joca.2012.09.009_bib37","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.joca.2010.02.001","article-title":"Assessing degeneration of human articular cartilage with ultra-short echo time (UTE) T2* mapping","volume":"18","author":"Williams","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2012.09.009_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.joca.2012.01.009","article-title":"UTE-T2* mapping detects sub-clinical meniscus injury after anterior cruciate ligament tear","author":"Williams","year":"2012","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2012.09.009_bib39","first-page":"221","article-title":"Modification of longitudinal relaxation time (T1) as a biomarker of patellar cartilage degeneration","volume":"52","author":"Sanz-Requena","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.joca.2012.09.009_bib40","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1148\/radiol.09081743","article-title":"Ultrashort TE MRI of the osteochondral junction of the knee at 3T: identification of anatomic structures contributing to signal intensity","volume":"254","author":"Bae","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.joca.2012.09.009_bib41","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.mri.2010.11.003","article-title":"Short T2 contrast with three-dimensional ultrashort echo time imaging","volume":"29","author":"Du","year":"2011","journal-title":"Magn Reson Imaging"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458412009715?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458412009715?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:30:08Z","timestamp":1761017408000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458412009715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S1063458412009715"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2012.09.009","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dual inversion recovery ultrashort echo time (DIR-UTE) imaging and quantification of the zone of calcified cartilage (ZCC)","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2012.09.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}