{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:20:29Z","timestamp":1793996429328,"version":"4.8.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.joca.2014.07.021","type":"journal-article","created":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T06:52:46Z","timestamp":1412059966000},"page":"1583-1589","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: a cross-sectional study"],"prefix":"10.1016","volume":"22","author":[{"given":"S.","family":"Hada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sadatsuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Futami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Yusup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Saita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Takazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ishijima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2014.07.021_bib1","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1056\/NEJMcp051726","article-title":"Clinical practice. Osteoarthritis of the knee","volume":"354","author":"Felson","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.joca.2014.07.021_bib2","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/jcp.21258","article-title":"Osteoarthritis","volume":"213","author":"Goldring","year":"2007","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.joca.2014.07.021_bib3","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S0140-6736(05)71086-2","article-title":"Pathogenesis and management of pain in osteoarthritis","volume":"365","author":"Dieppe","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.joca.2014.07.021_bib4","doi-asserted-by":"crossref","first-page":"R18","DOI":"10.1186\/ar4446","article-title":"Intra-articular hyaluronic acid injection versus oral non-steroidal anti-inflammatory drug for the treatment of knee osteoarthritis: a multi-center, randomized, open-label, non-inferiority trial","volume":"16","author":"Ishijima","year":"2014","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.joca.2014.07.021_bib5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/ar2655","article-title":"Developments in the scientific understanding of osteoarthritis","volume":"11","author":"Abramson","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.joca.2014.07.021_bib6","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s10067-010-1522-3","article-title":"Correlation between synovitis detected on enhanced-magnetic resonance imaging and a histological analysis with a patient-oriented outcome measure for Japanese patients with end-stage knee osteoarthritis receiving joint replacement surgery","volume":"29","author":"Liu","year":"2010","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.joca.2014.07.021_bib7","doi-asserted-by":"crossref","first-page":"R22","DOI":"10.1186\/ar3246","article-title":"Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis","volume":"13","author":"Ishijima","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.joca.2014.07.021_bib8","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.joca.2013.05.017","article-title":"Structural correlates of pain in joints with osteoarthritis","volume":"21","author":"Hunter","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib9","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1002\/art.22851","article-title":"Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging","volume":"56","author":"Felson","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2014.07.021_bib10","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","article-title":"Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association","volume":"29","author":"Altman","year":"1986","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2014.07.021_bib11","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2014.07.021_bib12","first-page":"1756","article-title":"Radiographic assessment of knee osteoarthritis: reproducibility and sensitivity to change","volume":"23","author":"Ravaud","year":"1996","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.joca.2014.07.021_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1136\/annrheumdis-2011-201070","article-title":"The role of varus and valgus alignment in the initial development of knee cartilage damage by MRI: the MOST study","volume":"72","author":"Sharma","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2014.07.021_bib14","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1136\/ard.54.11.872","article-title":"Accuracy and precision of joint space width measurements in standard and macroradiographs of osteoarthritic knees","volume":"54","author":"Buckland-Wright","year":"1995","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.joca.2014.07.021_bib15","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.joca.2013.05.014","article-title":"The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study","volume":"21","author":"Shimura","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib16","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s00774-013-0487-0","article-title":"Disability for daily living is a predictor for joint replacement in patients with end-stage knee osteoarthritis","volume":"32","author":"Liu","year":"2014","journal-title":"J\u00a0Bone Miner Metab"},{"key":"10.1016\/j.joca.2014.07.021_bib17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.joca.2003.11.003","article-title":"Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis","volume":"12","author":"Peterfy","year":"2004","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib18","doi-asserted-by":"crossref","first-page":"R153","DOI":"10.1186\/ar3469","article-title":"Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls\u2013data from the osteoarthritis initiative","volume":"13","author":"Joseph","year":"2011","journal-title":"Arthritis Res Ther"},{"issue":"Suppl A","key":"10.1016\/j.joca.2014.07.021_bib19","doi-asserted-by":"crossref","first-page":"A76","DOI":"10.1016\/j.joca.2006.03.010","article-title":"MRI of articular cartilage in OA: novel pulse sequences and compositional\/functional markers","volume":"14","author":"Gold","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib20","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/(SICI)1097-4636(1999)48:4<482::AID-JBM13>3.0.CO;2-M","article-title":"In\u00a0vivo characterization of indentation stiffness of articular cartilage in the normal human knee","volume":"48","author":"Lyyra","year":"1999","journal-title":"J\u00a0Biomed Mater Res"},{"key":"10.1016\/j.joca.2014.07.021_bib21","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.joca.2012.04.003","article-title":"Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years\u2013data from the Osteoarthritis Initiative","volume":"20","author":"Joseph","year":"2012","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib22","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1259\/bjr.71.841.9534696","article-title":"The magic angle phenomenon in tendons: effect of varying the MR echo time","volume":"71","author":"Peh","year":"1998","journal-title":"Br J Radiol"},{"key":"10.1016\/j.joca.2014.07.021_bib23","series-title":"Magnetic Resonance Imaging","first-page":"34","author":"Yoshioka","year":"2009"},{"key":"10.1016\/j.joca.2014.07.021_bib24","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.joca.2008.07.008","article-title":"Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort","volume":"17","author":"Wirth","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2014.07.021_bib25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/jmri.1150","article-title":"Spatial variation in cartilage T2 of the knee","volume":"14","author":"Smith","year":"2001","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.joca.2014.07.021_bib26","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1002\/art.38062","article-title":"High body mass index is associated with increased diurnal strains in the articular cartilage of the knee","volume":"65","author":"Widmyer","year":"2013","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2014.07.021_bib27","first-page":"491","article-title":"The effects of exercise on human articular cartilage","volume":"208","author":"Eckstein","year":"2006","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.joca.2014.07.021_bib28","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1016\/j.jbiomech.2010.02.035","article-title":"Mechanical asymmetry during articulation of tibial and femoral cartilages: local and overall compressive and shear deformation and properties","volume":"43","author":"Wong","year":"2010","journal-title":"J\u00a0Biomech"},{"key":"10.1016\/j.joca.2014.07.021_bib29","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1002\/art.20473","article-title":"Age dependency of cartilage magnetic resonance imaging T2 relaxation times in asymptomatic women","volume":"50","author":"Mosher","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.joca.2014.07.021_bib30","doi-asserted-by":"crossref","first-page":"344","DOI":"10.3109\/17453674.2010.483989","article-title":"The standing fixed flexion view detects narrowing of the joint space better than the standing extended view in patients with moderate osteoarthritis of the knee","volume":"81","author":"Niinimaki","year":"2010","journal-title":"Acta Orthop"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458414011947?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458414011947?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:37:53Z","timestamp":1761017873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458414011947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S1063458414011947"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2014.07.021","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: a cross-sectional study","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2014.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}