{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:38:47Z","timestamp":1791988727616,"version":"4.4.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes for Health","doi-asserted-by":"publisher","award":["R56 DE020097"],"award-info":[{"award-number":["R56 DE020097"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institutes for Health K12 TMJ Training","award":["5K12DE023583-02"],"award-info":[{"award-number":["5K12DE023583-02"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.joca.2016.11.008","type":"journal-article","created":{"date-parts":[[2016,11,27]],"date-time":"2016-11-27T01:00:48Z","timestamp":1480208448000},"page":"533-543","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Sex differences in the estrogen-dependent regulation of temporomandibular joint remodeling in altered loading"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5421-2370","authenticated-orcid":false,"given":"J.L.","family":"Robinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Cass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Aronson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Buttenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Drissi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.H.","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wadhwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2016.11.008_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.14219\/jada.archive.1993.0200","article-title":"Estimated prevalence and distribution of reported orofacial pain in the United States","volume":"124","author":"Lipton","year":"1993","journal-title":"J\u00a0Am Dent Assoc"},{"key":"10.1016\/j.joca.2016.11.008_bib2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.tripleo.2011.04.021","article-title":"Research diagnostic criteria for temporomandibular disorders: a systematic review of axis I epidemiologic findings","volume":"112","author":"Manfredini","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joca.2016.11.008_bib3","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1177\/154405910808700406","article-title":"Degenerative disorders of the temporomandibular joint: etiology, diagnosis, and treatment","volume":"87","author":"Tanaka","year":"2008","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.joca.2016.11.008_bib4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s10266-005-0056-7","article-title":"Pathogenesis of degenerative temporomandibular joint arthritides","volume":"93","author":"Milam","year":"2005","journal-title":"Odontology"},{"key":"10.1016\/j.joca.2016.11.008_bib5","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1016\/j.oooo.2012.03.023","article-title":"Distribution of diagnoses in a population of patients with temporomandibular disorders","volume":"114","author":"Manfredini","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.joca.2016.11.008_bib6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jdent.2010.01.006","article-title":"Age peaks of different RDC\/TMD diagnoses in a patient population","volume":"38","author":"Manfredini","year":"2010","journal-title":"J\u00a0Dent"},{"key":"10.1016\/j.joca.2016.11.008_bib7","first-page":"T27","article-title":"Clinical findings and pain symptoms as potential risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study","volume":"12","author":"Ohrbach","year":"2011","journal-title":"J\u00a0Pain"},{"key":"10.1016\/j.joca.2016.11.008_bib8","first-page":"208","article-title":"Occurrence of clinical signs of temporomandibular disorders in adult Finns","volume":"20","author":"Rutkiewicz","year":"2006","journal-title":"J\u00a0Orofac Pain"},{"key":"10.1016\/j.joca.2016.11.008_bib9","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1002\/dvdy.24130","article-title":"Genes that regulate morphogenesis and growth of the temporomandibular joint: a review","volume":"243","author":"Hinton","year":"2014","journal-title":"Dev Dyn"},{"key":"10.1016\/j.joca.2016.11.008_bib10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/0022034513476302","article-title":"The biology of TMJ growth modification: a review","volume":"92","author":"Owtad","year":"2013","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.joca.2016.11.008_bib11","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1177\/154405910508400802","article-title":"The adaptive remodeling of condylar cartilage\u2013a transition from chondrogenesis to osteogenesis","volume":"84","author":"Shen","year":"2005","journal-title":"J\u00a0Dent Res"},{"key":"10.1016\/j.joca.2016.11.008_bib12","series-title":"Fundamentals of Craniofacial Growth","first-page":"189","author":"Kantomaa","year":"1997"},{"issue":"Suppl 1","key":"10.1016\/j.joca.2016.11.008_bib13","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1034\/j.1600-0544.2003.252.x","article-title":"Micro X-ray computed tomography analysis for the evaluation of asymmetrical condylar growth in the rat","volume":"6","author":"Nakano","year":"2003","journal-title":"Orthod Craniofacial Res"},{"key":"10.1016\/j.joca.2016.11.008_bib14","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.aanat.2015.08.006","article-title":"Changes in collagens and chondrocytes in the temporomandibular joint cartilage in growing rats fed a liquid diet","volume":"202","author":"Uekita","year":"2015","journal-title":"Ann Anat"},{"key":"10.1016\/j.joca.2016.11.008_bib15","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.aanat.2005.10.008","article-title":"Distribution of tenascin-C and tenascin-X, apoptotic and proliferating cells in postnatal soft-diet rat temporomandibular joint (TMJ)","volume":"188","author":"Sato","year":"2006","journal-title":"Ann Anat"},{"key":"10.1016\/j.joca.2016.11.008_bib16","first-page":"28","volume":"vol. 3","author":"Carlson","year":"1980"},{"key":"10.1016\/j.joca.2016.11.008_bib17","series-title":"Determinants of Mandibular Form and Growth","first-page":"101","author":"Petrovic","year":"1975"},{"key":"10.1016\/j.joca.2016.11.008_bib18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/aja.1001820302","article-title":"Cellular stages in cartilage formation as revealed by morphometry, radioautography and type II collagen immunostaining of the mandibular condyle from weanling rats","volume":"182","author":"Luder","year":"1988","journal-title":"Am J Anat"},{"key":"10.1016\/j.joca.2016.11.008_bib19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0278-2391(82)80007-4","article-title":"The effects of immobilization on the primate temporomandibular joint: a histologic and histochemical study","volume":"40","author":"Glineburg","year":"1982","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib20","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/0278-2391(85)90158-2","article-title":"The effects of immobilization on the rabbit temporomandibular joint","volume":"43","author":"Lydiatt","year":"1985","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1053\/j.sodo.2005.07.005","article-title":"Regulation of growth in mandibular condylar cartilage","volume":"11","author":"Hinton","year":"2005","journal-title":"Semin Orthod"},{"key":"10.1016\/j.joca.2016.11.008_bib22","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/S0278-2391(99)90823-6","article-title":"Effects of estrogen on the condylar cartilage of the rat mandible in organ culture","volume":"57","author":"Ng","year":"1999","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib23","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.joms.2005.12.006","article-title":"Effects of estrogen on chondrocyte proliferation and collagen synthesis in skeletally mature articular cartilage","volume":"64","author":"Talwar","year":"2006","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib24","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0278-2391(00)90337-9","article-title":"Effect of estrogen replacement on temporomandibular joint remodeling in ovariectomized rats","volume":"58","author":"Yasuoka","year":"2000","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib25","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.joca.2008.05.021","article-title":"Altered functional loading causes differential effects in the subchondral bone and condylar cartilage in the temporomandibular joint from young mice","volume":"17","author":"Chen","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2016.11.008_bib26","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00223-011-9498-9","article-title":"Sex differences in chondrocyte maturation in the mandibular condyle from a decreased occlusal loading model","volume":"89","author":"Chen","year":"2011","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.joca.2016.11.008_bib27","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.archoralbio.2015.02.007","article-title":"Oestrogen receptor beta mediates decreased occlusal loading induced inhibition of chondrocyte maturation in female mice","volume":"60","author":"Polur","year":"2015","journal-title":"Archives Oral Biol"},{"key":"10.1016\/j.joca.2016.11.008_bib28","doi-asserted-by":"crossref","first-page":"4023","DOI":"10.1007\/s00018-013-1317-1","article-title":"The role of estrogen receptor \u03b1 in the regulation of bone and growth plate cartilage","volume":"70","author":"B\u00f6rjesson","year":"2013","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.joca.2016.11.008_bib29","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S8756-3282(01)00643-3","article-title":"Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-\u03b2 in bone remodeling in females but not in males","volume":"30","author":"Sims","year":"2002","journal-title":"Bone"},{"key":"10.1016\/j.joca.2016.11.008_bib30","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1359\/jbmr.0301203","article-title":"Estrogen receptor-\u03b2 inhibits skeletal growth and has the capacity to mediate growth plate fusion in female mice","volume":"19","author":"Chagin","year":"2004","journal-title":"J\u00a0Bone Min Res"},{"key":"10.1016\/j.joca.2016.11.008_bib31","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1677\/joe.0.1710229","article-title":"Estrogen receptor specificity in the regulation of the skeleton in female mice","volume":"171","author":"Lindberg","year":"2001","journal-title":"J\u00a0Endocrinol"},{"key":"10.1016\/j.joca.2016.11.008_bib32","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1172\/JCI6730","article-title":"Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(\u2212\/\u2212) mice","volume":"104","author":"Windahl","year":"1999","journal-title":"J\u00a0Clin Investig"},{"key":"10.1016\/j.joca.2016.11.008_bib33","doi-asserted-by":"crossref","first-page":"E484","DOI":"10.1152\/ajpendo.00189.2007","article-title":"The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor-\u03b2","volume":"293","author":"Saxon","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.joca.2016.11.008_bib34","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0003-9969(95)00021-G","article-title":"A\u00a0histochemical study of apoptosis in the reduced ameloblasts of erupting mouse molars","volume":"40","author":"Shibata","year":"1995","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.joca.2016.11.008_bib35","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1017\/S0016672300013306","article-title":"A\u00a0multivariate analysis of subline divergence in the shape of the mandible in C57BL\/Gr mice","volume":"21","author":"Festing","year":"1973","journal-title":"Genet Res"},{"key":"10.1016\/j.joca.2016.11.008_bib36","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/jbmr.1835","article-title":"Increased mandibular condylar growth in mice with estrogen receptor beta deficiency","volume":"28","author":"Kamiya","year":"2013","journal-title":"J\u00a0Bone Min Res"},{"key":"10.1016\/j.joca.2016.11.008_bib37","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/j.joca.2014.07.003","article-title":"Estrogen via estrogen receptor beta partially inhibits mandibular condylar cartilage growth","volume":"22","author":"Chen","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2016.11.008_bib38","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1038\/ijo.2015.102","article-title":"Estrogens protect male mice from obesity complications and influence glucocorticoid metabolism","volume":"39","author":"Dakin","year":"2015","journal-title":"Int J Obes"},{"key":"10.1016\/j.joca.2016.11.008_bib39","doi-asserted-by":"crossref","first-page":"5474","DOI":"10.1073\/pnas.97.10.5474","article-title":"Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice","volume":"97","author":"Vidal","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.joca.2016.11.008_bib40","first-page":"261","article-title":"Effect of estrogen and altered diet hardness on the expression of estrogen receptor alpha and matrix metalloproteinase-8 in rat condylar cartilage","volume":"25","author":"Orajarvi","year":"2011","journal-title":"J\u00a0Orofac Pain"},{"key":"10.1016\/j.joca.2016.11.008_bib41","first-page":"328","article-title":"Effect of estrogen and dietary loading on condylar cartilage","volume":"26","author":"Orajarvi","year":"2012","journal-title":"J\u00a0Orofac Pain"},{"key":"10.1016\/j.joca.2016.11.008_bib42","doi-asserted-by":"crossref","first-page":"297","DOI":"10.11607\/ofph.1287","article-title":"Effect of estrogen and food hardness on metabolism and turnover of condylar cartilage","volume":"29","author":"Orajarvi","year":"2015","journal-title":"J\u00a0Oral Facial Pain Headache"},{"issue":"11","key":"10.1016\/j.joca.2016.11.008_bib43","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.ijom.2015.06.025","article-title":"Dependence of cytokine levels on the sex of experimental animals: a pilot study on the effect of oestrogen in the temporomandibular joint synovial tissues","volume":"44","author":"Figueroba","year":"2015","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joca.2016.11.008_bib44","doi-asserted-by":"crossref","first-page":"R150","DOI":"10.1186\/ar4612","article-title":"The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis","volume":"16","author":"Engdahl","year":"2014","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.joca.2016.11.008_bib45","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.joca.2010.03.008","article-title":"GRIP1 enhances estrogen receptor alpha-dependent extracellular matrix gene expression in chondrogenic cells","volume":"18","author":"Kato","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.joca.2016.11.008_bib46","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1210\/en.2016-1402","article-title":"The bone sparing effects of 2-Methoxyestradiol are mediated via estrogen receptor-alpha in male mice","volume":"157","author":"Eriksson","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.joca.2016.11.008_bib47","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00298427","article-title":"Bone mineral density in patients with prostatic cancer treated with orchidectomy and with estrogens","volume":"57","author":"Eriksson","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.joca.2016.11.008_bib48","doi-asserted-by":"crossref","first-page":"13573","DOI":"10.1073\/pnas.2233084100","article-title":"Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice","volume":"100","author":"Moverare","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.joca.2016.11.008_bib49","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1073\/pnas.1220811110","article-title":"Estrogen receptor-\u03b1 in osteocytes is important for trabecular bone formation in male mice","volume":"110","author":"Windahl","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.joca.2016.11.008_bib50","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1056\/NEJM199410203311604","article-title":"Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man","volume":"331","author":"Smith","year":"1994","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.joca.2016.11.008_bib51","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S8756-3282(99)00179-9","article-title":"Changes of cancellous bone mass in rat mandibular condyle following ovariectomy","volume":"25","author":"Tanaka","year":"1999","journal-title":"Bone"},{"key":"10.1016\/j.joca.2016.11.008_bib52","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/aps.2011.136","article-title":"Dose-dependent effects of genistein on bone homeostasis in rats' mandibular subchondral bone","volume":"33","author":"Li","year":"2012","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.joca.2016.11.008_bib53","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.archoralbio.2009.01.018","article-title":"The effects of age and sex on the expression of oestrogen and its receptors in rat mandibular condylar cartilages","volume":"54","author":"Yu","year":"2009","journal-title":"Archives Oral Biol"},{"key":"10.1016\/j.joca.2016.11.008_bib54","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1002\/jbmr.2222","article-title":"Age-related impairment of bones' adaptive response to loading in mice is associated with sex-related deficiencies in osteoblasts but no change in osteocytes","volume":"29","author":"Meakin","year":"2014","journal-title":"J\u00a0Bone Min Res"},{"key":"10.1016\/j.joca.2016.11.008_bib55","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.jsbmb.2010.02.001","article-title":"Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography\u2013tandem mass spectrometry","volume":"121","author":"McNamara","year":"2010","journal-title":"J\u00a0Steroid Biochem Mol Biol"},{"key":"10.1016\/j.joca.2016.11.008_bib56","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1210\/jc.2005-1766","article-title":"Sex steroids and the periosteum \u2013 reconsidering the roles of androgens and estrogens in periosteal expansion","volume":"91","author":"Vanderschueren","year":"2006","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.joca.2016.11.008_bib57","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/nrendo.2014.120","article-title":"Reproductive endocrinology: functional effects of sex hormone-binding globulin variants","volume":"10","author":"Laurent","year":"2014","journal-title":"Nat Rev Endocrinol"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458416304095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458416304095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:44:43Z","timestamp":1761018283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458416304095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S1063458416304095"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2016.11.008","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex differences in the estrogen-dependent regulation of temporomandibular joint remodeling in altered loading","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2016.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}