{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T18:04:00Z","timestamp":1764785040279,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T00:00:00Z","timestamp":1673827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019771","name":"FP7","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.joca.2023.01.003","type":"journal-article","created":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T21:05:25Z","timestamp":1673643925000},"page":"414-420","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Potential surrogate outcomes in individuals at high risk for incident knee osteoarthritis"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6293-6707","authenticated-orcid":false,"given":"J.","family":"Runhaar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6926-0618","authenticated-orcid":false,"given":"M.","family":"van Middelkoop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.H.G.","family":"Oei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.M.A.","family":"Bierma-Zeinstra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10182","key":"10.1016\/j.joca.2023.01.003_bib1","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/S0140-6736(19)30417-9","article-title":"Osteoarthritis","volume":"393","author":"Hunter","year":"2019","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.joca.2023.01.003_bib2","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1001\/jama.2020.22171","article-title":"Diagnosis and treatment of hip and knee osteoarthritis: a review","volume":"325","author":"Katz","year":"2021","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.joca.2023.01.003_bib3","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s40520-020-01762-2","article-title":"Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data","volume":"33","author":"Leyland","year":"2021","journal-title":"Aging Clin Exp Res"},{"issue":"2","key":"10.1016\/j.joca.2023.01.003_bib4","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nrrheum.2015.135","article-title":"Strategies for the prevention of knee osteoarthritis","volume":"12","author":"Roos","year":"2016","journal-title":"Nat Rev Rheumatol"},{"issue":"12","key":"10.1016\/j.joca.2023.01.003_bib5","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/j.joca.2021.06.015","article-title":"A lifespan approach to osteoarthritis prevention","volume":"29","author":"Whittaker","year":"2021","journal-title":"Osteoarthritis Cartilage"},{"issue":"4","key":"10.1016\/j.joca.2023.01.003_bib6","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.joca.2023.01.003_bib7","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","article-title":"Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association","volume":"29","author":"Altman","year":"1986","journal-title":"Arthritis Rheum"},{"issue":"8","key":"10.1016\/j.joca.2023.01.003_bib8","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1093\/rheumatology\/kex145","article-title":"Long-term effects of a lifestyle intervention and oral glucosamine sulphate in primary care on incident knee OA in overweight women","volume":"56","author":"de Vos","year":"2017","journal-title":"Rheumatology (Oxford)"},{"issue":"1","key":"10.1016\/j.joca.2023.01.003_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/acr.23246","article-title":"Subjective crepitus as a risk factor for incident symptomatic knee osteoarthritis: data from the osteoarthritis initiative","volume":"70","author":"Lo","year":"2018","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"10","key":"10.1016\/j.joca.2023.01.003_bib10","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1177\/0363546507307396","article-title":"The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis","volume":"35","author":"Lohmander","year":"2007","journal-title":"Am J Sports Med"},{"issue":"8","key":"10.1016\/j.joca.2023.01.003_bib11","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.amjmed.2015.03.006","article-title":"Prevention of knee osteoarthritis in overweight females: the first preventive randomized controlled trial in osteoarthritis","volume":"128","author":"Runhaar","year":"2015","journal-title":"Am J Med"},{"issue":"10","key":"10.1016\/j.joca.2023.01.003_bib12","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.joca.2019.06.002","article-title":"The clinical and radiographic course of early knee and hip osteoarthritis over 10 years in CHECK (Cohort Hip and Cohort Knee)","volume":"27","author":"Schiphof","year":"2019","journal-title":"Osteoarthritis Cartilage"},{"issue":"Suppl_4","key":"10.1016\/j.joca.2023.01.003_bib13","doi-asserted-by":"crossref","first-page":"iv3","DOI":"10.1093\/rheumatology\/key014","article-title":"Can we prevent OA? Epidemiology and public health insights and implications","volume":"57","author":"Runhaar","year":"2018","journal-title":"Rheumatology (Oxford)"},{"issue":"6","key":"10.1016\/j.joca.2023.01.003_bib14","first-page":"1142","article-title":"From biomarker to surrogate outcome to osteoarthritis--what are the challenges?","volume":"32","author":"Lohmander","year":"2005","journal-title":"J\u00a0Rheumatol"},{"issue":"4","key":"10.1016\/j.joca.2023.01.003_bib15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/sim.4780080407","article-title":"Surrogate endpoints in clinical trials: definition and operational criteria","volume":"8","author":"Prentice","year":"1989","journal-title":"Stat Med"},{"issue":"3","key":"10.1016\/j.joca.2023.01.003_bib16","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jval.2016.10.011","article-title":"Time to review the role of surrogate end points in health policy: state of the art and the way forward","volume":"20","author":"Ciani","year":"2017","journal-title":"Value Health"},{"issue":"3","key":"10.1016\/j.joca.2023.01.003_bib17","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/biom.12071","article-title":"Surrogate measures and consistent surrogates","volume":"69","author":"Vanderweele","year":"2013","journal-title":"Biometrics"},{"issue":"21","key":"10.1016\/j.joca.2023.01.003_bib18","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1001\/jama.299.21.2543","article-title":"Patient-important outcomes in registered diabetes trials","volume":"299","author":"Gandhi","year":"2008","journal-title":"JAMA"},{"author":"Agency EM","key":"10.1016\/j.joca.2023.01.003_bib19"},{"issue":"8","key":"10.1016\/j.joca.2023.01.003_bib20","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.joca.2011.05.004","article-title":"Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score)","volume":"19","author":"Hunter","year":"2011","journal-title":"Osteoarthritis Cartilage"},{"issue":"4","key":"10.1016\/j.joca.2023.01.003_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.ejpain.2003.09.004","article-title":"Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale","volume":"8","author":"Salaffi","year":"2004","journal-title":"Eur J Pain"},{"issue":"1","key":"10.1016\/j.joca.2023.01.003_bib22","first-page":"131","article-title":"Minimal clinically important rehabilitation effects in patients with osteoarthritis of the lower extremities","volume":"29","author":"Angst","year":"2002","journal-title":"J\u00a0Rheumatol"},{"issue":"7","key":"10.1016\/j.joca.2023.01.003_bib23","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.joca.2009.01.007","article-title":"OARSI-OMERACT definition of relevant radiological progression in hip\/knee osteoarthritis","volume":"17","author":"Ornetti","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"issue":"10","key":"10.1016\/j.joca.2023.01.003_bib24","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.joca.2014.06.022","article-title":"How to define subregional osteoarthritis progression using semi-quantitative MRI osteoarthritis knee score (MOAKS)","volume":"22","author":"Runhaar","year":"2014","journal-title":"Osteoarthritis Cartilage"},{"issue":"1","key":"10.1016\/j.joca.2023.01.003_bib25","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1186\/s12891-022-05549-6","article-title":"Higher risk of knee arthroplasty during ten-year follow-up if baseline radiographic osteoarthritis involves the patellofemoral joint: a CHECK Cohort Study","volume":"23","author":"Macri","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"issue":"9","key":"10.1016\/j.joca.2023.01.003_bib26","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.joca.2022.05.011","article-title":"Effusion-synovitis worsening mediates the association between body mass index and Kellgren-Lawrence progression in obese individuals: data from the Osteoarthritis Initiative","volume":"30","author":"Banuls-Mirete","year":"2022","journal-title":"Osteoarthritis Cartilage"},{"issue":"4","key":"10.1016\/j.joca.2023.01.003_bib27","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1080\/03610911003650383","article-title":"How big is a big odds ratio? Interpreting the magnitudes of odds ratios in epidemiological studies","volume":"39","author":"Chen","year":"2010","journal-title":"Commun Stat Simul Comput"},{"issue":"10","key":"10.1016\/j.joca.2023.01.003_bib28","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/s41584-021-00673-4","article-title":"Early-stage symptomatic osteoarthritis of the knee - time for action","volume":"17","author":"Mahmoudian","year":"2021","journal-title":"Nat Rev Rheumatol"},{"issue":"7","key":"10.1016\/j.joca.2023.01.003_bib29","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/s41584-019-0237-3","article-title":"Establishing outcome measures in early knee osteoarthritis","volume":"15","author":"Emery","year":"2019","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.joca.2023.01.003_bib32","article-title":"Medial cartilage surface integrity as a surrogate measure for incident radiographic knee osteoarthritis following weight changes","author":"Runhaar","year":"2019","journal-title":"Cartilage"},{"issue":"4","key":"10.1016\/j.joca.2023.01.003_bib33","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3122\/jabfm.2019.04.180302","article-title":"Predicting knee pain and knee osteoarthritis among overweight women","volume":"32","author":"Landsmeer","year":"2019","journal-title":"J\u00a0Am Board Fam Med"},{"issue":"8","key":"10.1016\/j.joca.2023.01.003_bib34","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.joca.2017.03.014","article-title":"Baseline meniscal extrusion associated with incident knee osteoarthritis after 30 months in overweight and obese women","volume":"25","author":"van der Voet","year":"2017","journal-title":"Osteoarthritis Cartilage"},{"issue":"11","key":"10.1016\/j.joca.2023.01.003_bib35","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1093\/rheumatology\/keab228","article-title":"Factors associated with longitudinal change of meniscal extrusion in overweight women without clinical signs of osteoarthritis","volume":"60","author":"van der Voet","year":"2021","journal-title":"Rheumatology (Oxford)"},{"issue":"5","key":"10.1016\/j.joca.2023.01.003_bib36","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.3945\/ajcn.117.164046","article-title":"Surrogate disease markers as substitutes for chronic disease outcomes in studies of diet and chronic disease relations","volume":"106","author":"Yetley","year":"2017","journal-title":"Am J Clin Nutr"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458423000201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458423000201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:59:07Z","timestamp":1761019147000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458423000201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S1063458423000201"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2023.01.003","relation":{},"ISSN":["1063-4584"],"issn-type":[{"type":"print","value":"1063-4584"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential surrogate outcomes in individuals at high risk for incident knee osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2023.01.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International.","name":"copyright","label":"Copyright"}]}}