{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:25:52Z","timestamp":1793312752471,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772296"],"award-info":[{"award-number":["81772296"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.joca.2024.03.118","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T21:42:28Z","timestamp":1712439748000},"page":"869-880","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pioneering a chick embryo model to explore the intrauterine etiology of developmental dysplasia of the hip in oligohydramnios conditions"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-1572","authenticated-orcid":false,"given":"Shaoting","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Canavese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9797-5151","authenticated-orcid":false,"given":"Lianyong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2024.03.118_bib1","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004909.pub2","article-title":"Fetal movement counting for assessment of fetal wellbeing","author":"Mangesi","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.joca.2024.03.118_bib2","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1002\/jor.24415","article-title":"Effects of abnormal muscle forces on prenatal joint morphogenesis in mice","volume":"37","author":"Sotiriou","year":"2019","journal-title":"J Orthop Res"},{"key":"10.1016\/j.joca.2024.03.118_bib3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10237-011-0304-4","article-title":"Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis","volume":"11","author":"Nowlan","year":"2012","journal-title":"Biomech Model Mechanobiol"},{"key":"10.1016\/j.joca.2024.03.118_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1651-2227.2008.01102.x","article-title":"Incidence of fetal akinesia-hypokinesia deformation sequence: a population-based study","volume":"98","author":"Bayat","year":"2009","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.joca.2024.03.118_bib5","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s00198-019-04945-4","article-title":"Breech presentation is associated with lower adolescent tibial bone strength","volume":"30","author":"Tobias","year":"2019","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.joca.2024.03.118_bib6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1529-8027.2007.00140.x","article-title":"Morphometric aspects of peripheral nerves in adults and the elderly","volume":"12","author":"Moriyama","year":"2010","journal-title":"J Peripher Nerv Syst"},{"key":"10.1016\/j.joca.2024.03.118_bib7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00064-013-0237-4","article-title":"Congenital hip dysplasia in newborns: clinical and ultrasound examination, arthrography and closed reduction","volume":"25","author":"Placzek","year":"2013","journal-title":"Oper Orthop Traumatol"},{"key":"10.1016\/j.joca.2024.03.118_bib8","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2017.0593","article-title":"Stresses and strains on the human fetal skeleton during development","volume":"15","author":"Verbruggen","year":"2018","journal-title":"J R Soc Interface"},{"key":"10.1016\/j.joca.2024.03.118_bib9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/BPO.0000000000000134","article-title":"Is there a predilection for breech infants to demonstrate spontaneous stabilization of DDH instability?","volume":"34","author":"Sarkissian","year":"2014","journal-title":"J Pediatr Orthop"},{"key":"10.1016\/j.joca.2024.03.118_bib10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejogrb.2012.06.030","article-title":"Risk factors for developmental dysplasia of the hip: a meta-analysis","volume":"165","author":"de Hundt","year":"2012","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.joca.2024.03.118_bib11","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.bbrc.2017.02.065","article-title":"Cyclic compressive stress-induced scinderin regulates progress of developmental dysplasia of the hip","volume":"485","author":"Wang","year":"2017","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.joca.2024.03.118_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ocl.2005.12.001","article-title":"Growth and development of the child's hip","volume":"37","author":"Lee","year":"2006","journal-title":"Orthop Clin North Am"},{"key":"10.1016\/j.joca.2024.03.118_bib13","article-title":"Splinting for the non-operative management of developmental dysplasia of the hip (DDH) in children under six months of age","volume":"2017","author":"Dwan","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.joca.2024.03.118_bib14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.braindev.2018.10.009","article-title":"Correlation between human nervous system development and acquisition of fetal skills: an overview","volume":"41","author":"Borsani","year":"2019","journal-title":"Brain Dev"},{"key":"10.1016\/j.joca.2024.03.118_bib15","doi-asserted-by":"crossref","first-page":"4366","DOI":"10.3390\/ijerph19074366","article-title":"Computation of fetal kicking in various fetal health examinations: a systematic review","volume":"19","author":"Liu","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.joca.2024.03.118_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jbiomech.2018.07.016","article-title":"Altered biomechanical stimulation of the developing hip joint in presence of hip dysplasia risk factors","volume":"78","author":"Verbruggen","year":"2018","journal-title":"J Biomech"},{"key":"10.1016\/j.joca.2024.03.118_bib17","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.1016\/j.jbiomech.2015.06.002","article-title":"Effects of normal and abnormal loading conditions on morphogenesis of the prenatal hip joint: application to hip dysplasia","volume":"48","author":"Giorgi","year":"2015","journal-title":"J Biomech"},{"key":"10.1016\/j.joca.2024.03.118_bib18","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1016\/j.jbiomech.2016.09.029","article-title":"Characterising the effects of in vitro mechanical stimulation on morphogenesis of developing limb explants","volume":"49","author":"Chandaria","year":"2016","journal-title":"J Biomech"},{"key":"10.1016\/j.joca.2024.03.118_bib19","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/jor.22606","article-title":"Immobilized chicks as a model system for early-onset developmental dysplasia of the hip","volume":"32","author":"Nowlan","year":"2014","journal-title":"J Orthop Res"},{"key":"10.1016\/j.joca.2024.03.118_bib20","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/dvdy.236","article-title":"Quantifying the tolerance of chick hip joint development to temporary paralysis and the potential for recovery","volume":"250","author":"Bridglal","year":"2021","journal-title":"Dev Dyn"},{"key":"10.1016\/j.joca.2024.03.118_bib21","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.048913","article-title":"Joint development recovery on resumption of embryonic movement following paralysis","volume":"14","author":"Rolfe","year":"2021","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.joca.2024.03.118_bib22","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/BPB.0000000000000624","article-title":"Oligohydramnios: should it be considered a risk factor for developmental dysplasia of the hip?","volume":"28","author":"Manoukian","year":"2019","journal-title":"J Pediatr Orthop B"},{"key":"10.1016\/j.joca.2024.03.118_bib23","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1651-2227.2012.02667.x","article-title":"Short-term outcome among term singleton infants with intrapartum oligohydramnios","volume":"101","author":"Leibovitch","year":"2012","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.joca.2024.03.118_bib24","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/tera.1420460111","article-title":"Long bone development in extrinsic fetal akinesia: an experimental study in rat fetuses subjected to oligohydramnios","volume":"46","author":"Palacios","year":"1992","journal-title":"Teratology"},{"key":"10.1016\/j.joca.2024.03.118_bib25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/2191-219X-1-11","article-title":"Imaging technologies for preclinical models of bone and joint disorders","volume":"1","author":"Tremoleda","year":"2011","journal-title":"EJNMMI Res"},{"issue":"7","key":"10.1016\/j.joca.2024.03.118_bib26","article-title":"Diagnostic accuracy of ultrasound screening for fetal structural abnormalities during the first and second trimester of pregnancy in low-risk and unselected populations","volume":"2021","author":"Buijtendijk","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.joca.2024.03.118_bib27","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.2106\/JBJS.K.00720","article-title":"Does swaddling influence developmental dysplasia of the hip?: An experimental study of the traditional straight-leg swaddling model in neonatal rats","volume":"94","author":"Wang","year":"2012","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.joca.2024.03.118_bib28","doi-asserted-by":"crossref","first-page":"639","DOI":"10.5152\/balkanmedj.2016.150557","article-title":"Altered chondrocyte apoptosis status in developmental hip dysplasia in rabbits","volume":"33","author":"Wei","year":"2016","journal-title":"Balkan Med J"},{"key":"10.1016\/j.joca.2024.03.118_bib29","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.mod.2004.05.015","article-title":"The contribution of chicken embryology to the understanding of vertebrate limb development","volume":"121","author":"Tickle","year":"2004","journal-title":"Mech Dev"},{"key":"10.1016\/j.joca.2024.03.118_bib30","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.spinee.2011.03.010","article-title":"Experimental animal models in scoliosis research: a review of the literature","volume":"11","author":"Janssen","year":"2011","journal-title":"Spine J"},{"key":"10.1016\/j.joca.2024.03.118_bib31","doi-asserted-by":"crossref","first-page":"531","DOI":"10.22203\/eCM.v041a34","article-title":"Differential effect of frequency and duration of mechanical loading on fetal chick cartilage and bone development","volume":"41","author":"Khatib","year":"2021","journal-title":"Eur Cell Mater"},{"key":"10.1016\/j.joca.2024.03.118_bib32","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/bdrc.20184","article-title":"Mechanobiology of embryonic skeletal development: insights from animal models","volume":"90","author":"Nowlan","year":"2010","journal-title":"Birth Defects Res C Embryo Today"},{"key":"10.1016\/j.joca.2024.03.118_bib33","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/rheumatology\/keh436","article-title":"Hip dysplasia: a significant risk factor for the development of hip osteoarthritis. A cross-sectional survey","volume":"44","author":"Jacobsen","year":"2005","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.joca.2024.03.118_bib34","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s11999-016-4815-2","article-title":"The John Charnley Award: redefining the natural history of osteoarthritis in patients with hip dysplasia and impingement","volume":"475","author":"Wyles","year":"2017","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.joca.2024.03.118_bib35","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2106\/00004623-198062020-00012","article-title":"Post-reduction avascular necrosis in congenital dislocation of the hip","volume":"62","author":"Cooperman","year":"1980","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.joca.2024.03.118_bib36","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.actbio.2020.05.005","article-title":"Early changes in cartilage pericellular matrix micromechanobiology portend the onset of post-traumatic osteoarthritis","volume":"111","author":"Chery","year":"2020","journal-title":"Acta Biomater"},{"key":"10.1016\/j.joca.2024.03.118_bib37","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3109\/03008207.2015.1009052","article-title":"Observation of sGAG content of human hip joint cartilage in different old age groups based on EPIC micro-CT","volume":"56","author":"Li","year":"2015","journal-title":"Connect Tissue Res"},{"key":"10.1016\/j.joca.2024.03.118_bib38","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.joca.2008.07.015","article-title":"Quantitative assessment of articular cartilage morphology via EPIC-microCT","volume":"17","author":"Xie","year":"2009","journal-title":"Osteoarthr Cartil"},{"key":"10.1016\/j.joca.2024.03.118_bib39","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/BPO.0000000000002228","article-title":"Risk factors for avascular necrosis after closed reduction for developmental dysplasia of the hip","volume":"42","author":"Bian","year":"2022","journal-title":"J Pediatr Orthop"},{"key":"10.1016\/j.joca.2024.03.118_bib40","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1302\/1863-2548.12.180024","article-title":"Long-term outcome of closed reduction in late-detected hip dislocation: 60 patients aged six to 36 months at diagnosis followed to a mean age of 58 years","volume":"12","author":"Terjesen","year":"2018","journal-title":"J Child Orthop"},{"key":"10.1016\/j.joca.2024.03.118_bib41","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s00264-006-0113-z","article-title":"The incidence of avascular necrosis of the healthy, contralateral femoral head at the end of the use of Pavlik harness in unilateral hip dysplasia","volume":"30","author":"Pap","year":"2006","journal-title":"Int Orthop"},{"key":"10.1016\/j.joca.2024.03.118_bib42","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1302\/1863-2548.15.210059","article-title":"Does the vascular development of the femoral head correlate with the incidence of avascular necrosis of the proximal femoral epiphysis in children with developmental dysplasia of the hip treated by closed reduction?","volume":"15","author":"Wu","year":"2021","journal-title":"J Child Orthop"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458424011488?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458424011488?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T12:00:34Z","timestamp":1751371234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458424011488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":42,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S1063458424011488"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2024.03.118","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pioneering a chick embryo model to explore the intrauterine etiology of developmental dysplasia of the hip in oligohydramnios conditions","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2024.03.118","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}