{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T01:28:08Z","timestamp":1773883688993,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020098","name":"Innovative Medicines Initiative 2 Joint Undertaking","doi-asserted-by":"publisher","award":["115770"],"award-info":[{"award-number":["115770"]}],"id":[{"id":"10.13039\/100020098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010767","name":"Innovative Medicines Initiative","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013322","name":"European Federation of Pharmaceutical Industries and Associations","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.joca.2025.11.011","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T16:43:15Z","timestamp":1764348195000},"page":"297-303","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3892-6987","authenticated-orcid":false,"given":"Eva A.","family":"Bax","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roel J.H.","family":"Custers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke","family":"van Egmond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moyo C.","family":"Kruyt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Rayegan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9294-2307","authenticated-orcid":false,"given":"Margreet","family":"Kloppenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9821-7635","authenticated-orcid":false,"given":"Francisco J.","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7810-2216","authenticated-orcid":false,"given":"Ida K.","family":"Haugen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8252-7815","authenticated-orcid":false,"given":"Francis","family":"Berenbaum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9238-7350","authenticated-orcid":false,"given":"Frank W.","family":"Roemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harrie","family":"Weinans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon C.","family":"Mastbergen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1929-6350","authenticated-orcid":false,"given":"Myl\u00e8ne P.","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.joca.2025.11.011_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-035101","volume":"10","author":"van Helvoort","year":"2020","journal-title":"BMJ Open"},{"issue":"11","key":"10.1016\/j.joca.2025.11.011_bib2","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.joca.2021.07.013","article-title":"Performance of knee image digital analysis of radiographs of patients with end-stage knee osteoarthritis","volume":"29","author":"Jansen","year":"2021","journal-title":"Osteoarthr. Cartil."},{"issue":"8","key":"10.1016\/j.joca.2025.11.011_bib3","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.joca.2020.04.003","article-title":"A novel quantitative metric for joint space width: data from the Osteoarthritis Initiative (OAI)","volume":"28","author":"Paixao","year":"2020","journal-title":"Osteoarthr. Cartil."},{"issue":"6","key":"10.1016\/j.joca.2025.11.011_bib4","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.joca.2008.11.001","article-title":"Location specific radiographic joint space width for osteoarthritis progression","volume":"17","author":"Neumann","year":"2009","journal-title":"Osteoarthr. Cartil."},{"issue":"2","key":"10.1016\/j.joca.2025.11.011_bib5","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.joca.2007.06.009","article-title":"Knee Images Digital Analysis (KIDA): a novel method to quantify individual radiographic features of knee osteoarthritis in detail","volume":"16","author":"Marijnissen","year":"2008","journal-title":"Osteoarthr. Cartil."},{"issue":"12","key":"10.1016\/j.joca.2025.11.011_bib6","doi-asserted-by":"crossref","first-page":"5673","DOI":"10.1007\/s00167-023-07616-4","article-title":"The joint line convergence angle (JLCA) correlates with intra-articular arthritis","volume":"31","author":"Mabrouk","year":"2023","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"issue":"4","key":"10.1016\/j.joca.2025.11.011_bib7","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.joca.2018.12.013","article-title":"Risk factor heterogeneity for medial and lateral compartment knee osteoarthritis: analysis of two prospective cohorts","volume":"27","author":"Wei","year":"2019","journal-title":"Osteoarthr. Cartil."},{"issue":"4","key":"10.1016\/j.joca.2025.11.011_bib8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.joca.2020.10.011","article-title":"The compartmental distribution of knee osteoarthritis \u2013 a systematic review and meta-analysis","volume":"29","author":"Stoddart","year":"2021","journal-title":"Osteoarthr. Cartil."},{"issue":"6","key":"10.1016\/j.joca.2025.11.011_bib9","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1007\/s00330-015-3977-8","article-title":"Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative","volume":"26","author":"Eckstein","year":"2016","journal-title":"Eur. Radio."},{"issue":"7","key":"10.1016\/j.joca.2025.11.011_bib10","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/acr.20148","article-title":"Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: analysis of longitudinal data from the Osteoarthritis Initiative","volume":"62","author":"Duryea","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"4","key":"10.1016\/j.joca.2025.11.011_bib11","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.joca.2012.12.010","article-title":"Correlations between radiographic assessments and MRI features of knee osteoarthritis \u2013 a cross-sectional study","volume":"21","author":"Gudbergsen","year":"2013","journal-title":"Osteoarthr. Cartil."},{"issue":"1","key":"10.1016\/j.joca.2025.11.011_bib12","doi-asserted-by":"crossref","first-page":"8427","DOI":"10.1038\/s41598-020-64643-8","article-title":"Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data","volume":"10","author":"Widera","year":"2020","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.joca.2025.11.011_bib13","article-title":"Reproducibility of the semiflexed (metatarsophalangeal) radiographic knee position and automated measurements of medial tibiofemoral joint space width in a multicenter clinical trial of knee osteoarthritis","volume":"31","author":"Buckland-Wright","year":"2004","journal-title":"J. Rheuma"},{"issue":"4","key":"10.1016\/j.joca.2025.11.011_bib14","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1177\/19476035231166126","article-title":"Automated Radiographic Measurements of Knee Osteoarthritis","volume":"14","author":"Rayegan","year":"2023","journal-title":"Cartilage"},{"key":"10.1016\/j.joca.2025.11.011_bib15","series-title":"Principles of Deformity Correction","first-page":"816","author":"Paley","year":"2002"},{"issue":"8","key":"10.1016\/j.joca.2025.11.011_bib16","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.joca.2011.05.004","article-title":"Evolution of semiquantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score)","volume":"19","author":"Hunter","year":"2011","journal-title":"Osteoarthr. Cartil. \/ OARS Osteoarthr. Res. Soc."},{"issue":"3","key":"10.1016\/j.joca.2025.11.011_bib17","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1002\/art.39970","article-title":"Brief Report: Partial- and Full-Thickness Focal Cartilage Defects Contribute Equally to Development of New Cartilage Damage in Knee Osteoarthritis: The Multicenter Osteoarthritis Study","volume":"69","author":"Guermazi","year":"2017","journal-title":"Arthritis Rheuma"},{"issue":"1","key":"10.1016\/j.joca.2025.11.011_bib18","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1186\/s12891-022-05926-1","article-title":"Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort","volume":"23","author":"Roemer","year":"2022","journal-title":"BMC Musculoskelet. Disord."},{"issue":"7","key":"10.1016\/j.joca.2025.11.011_bib19","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/acr.20148","article-title":"Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: analysis of longitudinal data from the Osteoarthritis Initiative","volume":"62","author":"Duryea","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"4","key":"10.1016\/j.joca.2025.11.011_bib20","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1177\/19476035231226418","article-title":"Comparison of Clinical Efficacy and Mechanical Characteristics of Two Knee Distraction Devices With Relevance for Clinical Practice","volume":"15","author":"Struik","year":"2024","journal-title":"Cartilage"},{"issue":"5","key":"10.1016\/j.joca.2025.11.011_bib21","doi-asserted-by":"crossref","DOI":"10.31661\/jbpe.v0i0.1912-1003","article-title":"Comparison of Joint Space Width Determinations in Grade I and II Knee Osteoarthritis Patients Using Manual and Automatic Measurements","volume":"11","author":"Sugiyanto","year":"2021","journal-title":"J. Biomed. Phys. Eng."},{"issue":"12","key":"10.1016\/j.joca.2025.11.011_bib22","doi-asserted-by":"crossref","first-page":"5673","DOI":"10.1007\/s00167-023-07616-4","article-title":"The joint line convergence angle (JLCA) correlates with intra-articular arthritis","volume":"31","author":"Mabrouk","year":"2023","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"10.1016\/j.joca.2025.11.011_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.ostima.2025.100357","article-title":"Impact of Knee Positioning on Differences Between Weight-Bearing minimal Joint Space Width and Non-Weight-Bearing MRI Cartilage Thickness: A Cross-Sectional and Longitudinal Analysis in the IMI-APPROACH","author":"Bax","year":"2025","journal-title":"Osteoarthr. Imaging"},{"issue":"11","key":"10.1016\/j.joca.2025.11.011_bib24","first-page":"1107","article-title":"Superiority of Multiple-Joint Space Width over Minimum-Joint Space Width Approach in the Machine Learning for Radiographic Severity and Knee Osteoarthritis Progression","volume":"10","author":"Cheung","year":"2021","journal-title":"Biol. (Basel)"},{"issue":"7","key":"10.1016\/j.joca.2025.11.011_bib25","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s00256-022-04259-3","article-title":"Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort","volume":"52","author":"Jansen","year":"2023","journal-title":"Skelet. Radio."},{"issue":"1","key":"10.1016\/j.joca.2025.11.011_bib26","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12880-022-00799-1","article-title":"T2 mapping for knee cartilage degeneration in young patients with mild symptoms","volume":"22","author":"Zhao","year":"2022","journal-title":"BMC Med Imaging"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458425012397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458425012397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T19:42:46Z","timestamp":1773862966000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458425012397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S1063458425012397"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2025.11.011","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2025.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International.","name":"copyright","label":"Copyright"}]}}