{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:06:59Z","timestamp":1789578419783,"version":"build-2803163510"},"reference-count":61,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DE019284\\u201311A1"],"award-info":[{"award-number":["R01 DE019284\\u201311A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["S10D030212"],"award-info":[{"award-number":["S10D030212"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R34 DE033595"],"award-info":[{"award-number":["R34 DE033595"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["P30 AR075055"],"award-info":[{"award-number":["P30 AR075055"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["S10 RR026475\\u201301"],"award-info":[{"award-number":["S10 RR026475\\u201301"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005648","name":"American Association of Orthodontists Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005648","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013400","name":"American Academy of Optometry Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013400","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.joca.2025.12.019","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T16:16:36Z","timestamp":1766852196000},"page":"575-588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Osteocyte-Intrinsic MMP13 exacerbates injury-induced temporomandibular joint osteoarthritis"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2245-4612","authenticated-orcid":false,"given":"Cristal S.","family":"Yee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4119-3152","authenticated-orcid":false,"given":"Marianne","family":"Demirdji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0581-2839","authenticated-orcid":false,"given":"Karsyn N.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena D.","family":"Larios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7612-1816","authenticated-orcid":false,"given":"Christoforos","family":"Meliadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9140-3509","authenticated-orcid":false,"given":"Clarissa Aguirre","family":"Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrison B.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peggi M.","family":"Angel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0271-9548","authenticated-orcid":false,"given":"Sunil","family":"Kapila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Alliston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2025.12.019_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/srep44618","article-title":"Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis","volume":"7","author":"Fowler","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib2","doi-asserted-by":"crossref","first-page":"E359","DOI":"10.36076\/ppj.2014\/17\/E359","article-title":"Prevalence of suicidal ideation in patients with chronic non-cancer pain referred to a behaviorally based pain program","volume":"17","author":"Cheatle","year":"2014","journal-title":"Pain. Physician"},{"key":"10.1016\/j.joca.2025.12.019_bib3","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41413-019-0070-y","article-title":"Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis","volume":"7","author":"Mazur","year":"2019","journal-title":"Bone Res."},{"key":"10.1016\/j.joca.2025.12.019_bib4","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/art.41548","article-title":"Mechanosensitive control of articular cartilage and subchondral bone homeostasis in mice requires osteocytic transforming growth factor beta signaling","volume":"73","author":"Bailey","year":"2021","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.joca.2025.12.019_bib5","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1016\/j.joca.2023.05.005","article-title":"Microstructural and cellular characterisation of the subchondral trabecular bone in human knee and hip osteoarthritis using synchrotron tomography","volume":"31","author":"Muratovic","year":"2023","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2025.12.019_bib6","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.joca.2024.01.007","article-title":"Alterations in compositional and cellular properties of the subchondral bone are linked to cartilage degeneration in hip osteoarthritis","volume":"32","author":"Delsmann","year":"2024","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2025.12.019_bib7","doi-asserted-by":"crossref","first-page":"406","DOI":"10.7150\/ijbs.4221","article-title":"Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: a possible pathological role in subchondral bone sclerosis","volume":"8","author":"Jaiprakash","year":"2012","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.joca.2025.12.019_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/jbmr.320","article-title":"The amazing osteocyte","volume":"26","author":"Bonewald","year":"2011","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.bone.2015.02.016","article-title":"Quantifying the osteocyte network in the human skeleton","volume":"75","author":"Buenzli","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s11914-019-00514-0","article-title":"Investigating osteocytic perilacunar\/canalicular remodeling","volume":"17","author":"Yee","year":"2019","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib11","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/jbmr.1567","article-title":"Demonstration of osteocytic perilacunar\/canalicular remodeling in mice during lactation","volume":"27","author":"Qing","year":"2012","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib12","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1002\/jbmr.1646","article-title":"Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance","volume":"27","author":"Tang","year":"2012","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib13","doi-asserted-by":"crossref","first-page":"33814","DOI":"10.1074\/jbc.M607290200","article-title":"A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism","volume":"281","author":"Inoue","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.joca.2025.12.019_bib14","doi-asserted-by":"crossref","first-page":"2878","DOI":"10.1096\/fj.201700919RRR","article-title":"MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production","volume":"32","author":"Delgado-Calle","year":"2018","journal-title":"FASEB J."},{"key":"10.1016\/j.joca.2025.12.019_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.coph.2016.02.003","article-title":"Osteocytes: the master cells in bone remodelling","volume":"28","author":"Prideaux","year":"2016","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.joca.2025.12.019_bib16","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41413-023-00303-7","article-title":"Aging impairs the osteocytic regulation of collagen integrity and bone quality","volume":"12","author":"Schurman","year":"2024","journal-title":"Bone Res."},{"key":"10.1016\/j.joca.2025.12.019_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bonr.2018.09.004","article-title":"Glucocorticoids cause mandibular bone fragility and suppress osteocyte perilacunar-canalicular remodeling","volume":"9","author":"Alemi","year":"2018","journal-title":"Bone Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib18","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1016\/j.celrep.2017.10.115","article-title":"Osteocyte-intrinsic TGF-beta signaling regulates bone quality through perilacunar\/canalicular remodeling","volume":"21","author":"Dole","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib19","doi-asserted-by":"crossref","first-page":"9148","DOI":"10.1038\/srep09148","article-title":"Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis","volume":"5","author":"Kobayashi","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib20","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jbmr.3876","article-title":"YAP and TAZ mediate osteocyte perilacunar\/canalicular remodeling","volume":"35","author":"Kegelman","year":"2020","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib21","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1242\/dev.01461","article-title":"Altered endochondral bone development in matrix metalloproteinase 13-deficient mice","volume":"131","author":"Stickens","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.joca.2025.12.019_bib22","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1177\/154405910708600404","article-title":"DMP1-targeted Cre expression in odontoblasts and osteocytes","volume":"86","author":"Lu","year":"2007","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib23","article-title":"Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.joca.2025.12.019_bib24","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.joca.2005.03.004","article-title":"Osteoarthritis development in novel experimental mouse models induced by knee joint instability","volume":"13","author":"Kamekura","year":"2005","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2025.12.019_bib25","series-title":"Fast Green Stain for Cartilage","author":"Safranin","year":"2017"},{"key":"10.1016\/j.joca.2025.12.019_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1342938","article-title":"The osteocytic actions of glucocorticoids on bone mass, mechanical properties, or perilacunar remodeling outcomes are not rescued by PTH(1-34)","volume":"15","author":"Yee","year":"2024","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.joca.2025.12.019_bib27","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.archoralbio.2016.05.007","article-title":"Malocclusion model of temporomandibular joint osteoarthritis in mice with and without receptor for advanced glycation end products","volume":"69","author":"Matias","year":"2016","journal-title":"Arch. Oral. Biol."},{"key":"10.1016\/j.joca.2025.12.019_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.bone.2016.04.010","article-title":"Parallel mechanisms suppress cochlear bone remodeling to protect hearing","volume":"89","author":"Jauregui","year":"2016","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib29","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF01676192","article-title":"Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level","volume":"18","author":"Ploton","year":"1986","journal-title":"Histochem J."},{"issue":"3","key":"10.1016\/j.joca.2025.12.019_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S0074-02761991000700002","article-title":"The use of the Picrosirius-polarization method for the study of the biopathology of collagen","volume":"86","author":"Montes","year":"1991","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.joca.2025.12.019_bib31","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s10237-011-0325-z","article-title":"Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy","volume":"11","author":"Rezakhaniha","year":"2012","journal-title":"Biomech. Model Mechanobiol."},{"key":"10.1016\/j.joca.2025.12.019_bib32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.bone.2017.03.051","article-title":"Open source software for semi-automated histomorphometry of bone resorption and formation parameters","volume":"99","author":"van 't Hof","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib33","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1002\/jbmr.4023","article-title":"TGFbeta regulation of perilacunar\/canalicular remodeling is sexually dimorphic","volume":"35","author":"Dole","year":"2020","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib34","doi-asserted-by":"crossref","DOI":"10.3791\/53746","article-title":"The monoiodoacetate model of osteoarthritis pain in the mouse","author":"Pitcher","year":"2016","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.joca.2025.12.019_bib35","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1002\/art.1780400917","article-title":"Mono-iodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry","volume":"40","author":"Guingamp","year":"1997","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.joca.2025.12.019_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-95251-9","article-title":"The expression of Netrin-1 in the MIA-induced osteoarthritic temporomandibular joint in mice","volume":"11","author":"Xiao","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib37","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.neulet.2004.08.023","article-title":"The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats?","volume":"370","author":"Combe","year":"2004","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.joca.2025.12.019_bib38","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1111\/j.1471-4159.1971.tb00013.x","article-title":"Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid","volume":"18","author":"Sabri","year":"1971","journal-title":"J. Neurochem."},{"key":"10.1016\/j.joca.2025.12.019_bib39","first-page":"1001","article-title":"Development of osteoarthritic lesions in mice by \"metabolic\" and \"mechanical\" alterations in the knee joints","volume":"135","author":"van der Kraan","year":"1989","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.joca.2025.12.019_bib40","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/art.40351","article-title":"Loading-induced reduction in sclerostin as a mechanism of subchondral bone plate sclerosis in mouse knee joints during late-stage osteoarthritis","volume":"70","author":"Jia","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.joca.2025.12.019_bib41","article-title":"Tissue and extracellular matrix remodeling of the subchondral bone during osteoarthritis of knee joints as revealed by spatial mass spectrometry imaging","author":"Schurman","year":"2025","journal-title":"bioRxiv"},{"key":"10.1016\/j.joca.2025.12.019_bib42","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1002\/art.37799","article-title":"Matrix-assisted laser desorption ionization-imaging mass spectrometry: a new methodology to study human osteoarthritic cartilage","volume":"65","author":"Cillero-Pastor","year":"2013","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.joca.2025.12.019_bib43","doi-asserted-by":"crossref","DOI":"10.1186\/ar4560","article-title":"Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage","volume":"16","author":"Peffers","year":"2014","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.joca.2025.12.019_bib44","article-title":"Animal models of temporomandibular joint osteoarthritis: classification and selection","volume":"13","author":"Zhao","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.joca.2025.12.019_bib45","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1177\/154405910508400802","article-title":"The adaptive remodeling of condylar cartilage---a transition from chondrogenesis to osteogenesis","volume":"84","author":"Shen","year":"2005","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib46","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.bone.2015.04.035","article-title":"Bone development","volume":"80","author":"Berendsen","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib47","article-title":"Knee orthopedics as a template for the temporomandibular joint","volume":"2","author":"Bielajew","year":"2021","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.joca.2025.12.019_bib48","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1177\/0022034512468749","article-title":"Shear mechanics of the TMJ disc: relationship to common clinical observations","volume":"92","author":"Juran","year":"2013","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib49","article-title":"Extracellular vesicles in osteoarthritis of peripheral joint and temporomandibular joint","volume":"14","author":"Yang","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.joca.2025.12.019_bib50","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/odi.12353","article-title":"Mouse genetic models for temporomandibular joint development and disorders","volume":"22","author":"Suzuki","year":"2016","journal-title":"Oral. Dis."},{"key":"10.1016\/j.joca.2025.12.019_bib51","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/978-1-4939-1215-5_23","article-title":"Experimental osteoarthritis models in mice","volume":"1194","author":"Lorenz","year":"2014","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.joca.2025.12.019_bib52","doi-asserted-by":"crossref","DOI":"10.1186\/ar3103","article-title":"Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis","volume":"12","author":"Bellido","year":"2010","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.joca.2025.12.019_bib53","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.bone.2012.12.044","article-title":"Alendronate protects against articular cartilage erosion by inhibiting subchondral bone loss in ovariectomized rats","volume":"53","author":"Zhu","year":"2013","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib54","doi-asserted-by":"crossref","DOI":"10.1186\/ar2434","article-title":"Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity","volume":"10","author":"Karsdal","year":"2008","journal-title":"Arthritis Res Ther."},{"key":"10.1016\/j.joca.2025.12.019_bib55","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1177\/0022034517707515","article-title":"Association of Condylar bone quality with TMJ osteoarthritis","volume":"96","author":"Shi","year":"2017","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.joca.2025.12.019_bib56","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.joms.2013.08.022","article-title":"Inflammation is more distinct in temporomandibular joint osteoarthritis compared to the knee joint","volume":"72","author":"Vos","year":"2014","journal-title":"J. Oral. Maxillofac. Surg."},{"key":"10.1016\/j.joca.2025.12.019_bib57","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00056-021-00309-y","article-title":"Differential gene expression response of synovial fibroblasts from temporomandibular joints and knee joints to dynamic tensile stress","volume":"83","author":"Nazet","year":"2022","journal-title":"J. Orofac. Orthop."},{"key":"10.1016\/j.joca.2025.12.019_bib58","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.bone.2011.11.030","article-title":"Elevated cross-talk between subchondral bone and cartilage in osteoarthritic joints","volume":"51","author":"Pan","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.joca.2025.12.019_bib59","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-14470-w","article-title":"Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency","volume":"12","author":"Ponte","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2025.12.019_bib60","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1002\/art.25002","article-title":"Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development","volume":"60","author":"Little","year":"2009","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.joca.2025.12.019_bib61","doi-asserted-by":"crossref","DOI":"10.1186\/ar4133","article-title":"MMP13 is a critical target gene during the progression of osteoarthritis","volume":"15","author":"Wang","year":"2013","journal-title":"Arthritis Res. Ther."}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458425012828?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458425012828?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:30:30Z","timestamp":1781670630000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458425012828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S1063458425012828"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2025.12.019","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteocyte-Intrinsic MMP13 exacerbates injury-induced temporomandibular joint osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2025.12.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International.","name":"copyright","label":"Copyright"}]}}