{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:47:23Z","timestamp":1791992843317,"version":"4.4.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.joca.2026.06.011","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T06:52:27Z","timestamp":1784271147000},"page":"1590-1601","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of an impingement induced, reversible degenerative meniscus tear animal model to analyze pathogenesis and potential recovery from meniscus degeneration"],"prefix":"10.1016","volume":"34","author":[{"given":"Yong Jun","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujin","family":"Noh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Woong","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Young","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2865-173X","authenticated-orcid":false,"given":"Sumin","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-6684","authenticated-orcid":false,"given":"Do Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joca.2026.06.011_bib1","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1056\/NEJMoa0800777","article-title":"Incidental meniscal findings on knee MRI in middle-aged and elderly persons","volume":"359","author":"Englund","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.joca.2026.06.011_bib2","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nrrheum.2012.69","article-title":"Meniscus pathology, osteoarthritis and the treatment controversy","volume":"8","author":"Englund","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.joca.2026.06.011_bib3","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.rdc.2009.08.004","article-title":"The meniscus in knee osteoarthritis","volume":"35","author":"Englund","year":"2009","journal-title":"Rheum. Dis. Clin. N. Am."},{"key":"10.1016\/j.joca.2026.06.011_bib4","doi-asserted-by":"crossref","first-page":"S237","DOI":"10.1016\/j.otsr.2017.08.003","article-title":"Management of traumatic meniscal tear and degenerative meniscal lesions. Save the meniscus","volume":"103","author":"Beaufils","year":"2017","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"10.1016\/j.joca.2026.06.011_bib5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/ca.22456","article-title":"The human meniscus: a review of anatomy, function, injury, and advances in treatment","volume":"28","author":"Fox","year":"2015","journal-title":"Clin. Anat."},{"key":"10.1016\/j.joca.2026.06.011_bib6","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jos.2018.04.003","article-title":"Trends in isolated meniscus repair and meniscectomy in Japan, 2011\u20132016","volume":"23","author":"Katano","year":"2018","journal-title":"J. Orthop. Sci."},{"key":"10.1016\/j.joca.2026.06.011_bib7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.arthro.2010.08.016","article-title":"Does arthroscopic partial meniscectomy result in knee osteoarthritis? A systematic review with a minimum of 8 years' follow-up","volume":"27","author":"Petty","year":"2011","journal-title":"Arthroscopy"},{"issue":"1","key":"10.1016\/j.joca.2026.06.011_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.arthro.2003.09.025","article-title":"Complex knee reconstruction: articular cartilage treatment options","volume":"19","author":"Cole","year":"2003","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib9","first-page":"3782","article-title":"Biosynthetic scaffolds for partial meniscal loss: a systematic review from animal models to clinical practice","volume":"6","author":"Veronesi","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.joca.2026.06.011_bib10","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/term.1760","article-title":"Animal models for meniscus repair and regeneration","volume":"9","author":"Deponti","year":"2015","journal-title":"J. Tissue Eng. Regen. Med."},{"key":"10.1016\/j.joca.2026.06.011_bib11","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1002\/jor.24645","article-title":"Comparison between two rabbit models of posttraumatic osteoarthritis: a longitudinal tear in the medial meniscus and anterior cruciate ligament transection","volume":"38","author":"Huang","year":"2020","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.joca.2026.06.011_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202301180","article-title":"Selective extracellular matrix guided mesenchymal stem cell self-aggregate engineering for replication of meniscal zonal tissue gradient in a porcine meniscectomy model","volume":"12","author":"Noh","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.joca.2026.06.011_bib13","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1177\/0363546516638342","article-title":"Local administration of simvastatin stimulates healing of an avascular meniscus in a rabbit model of a meniscal defect","volume":"44","author":"Zhang","year":"2016","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.joca.2026.06.011_bib14","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3389\/fvets.2019.00292","article-title":"Large animal models for anterior cruciate ligament research","volume":"6","author":"Bascunan","year":"2019","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.joca.2026.06.011_bib15","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1002\/art.1780341214","article-title":"Osteoarthritic changes in canine articular cartilage, subchondral bone, and synovium fifty-four months after transection of the anterior cruciate ligament","volume":"34","author":"Brandt","year":"1991","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.joca.2026.06.011_bib16","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1007\/s00402-015-2309-4","article-title":"Meniscal tears associated with anterior cruciate ligament injury","volume":"135","author":"Hagino","year":"2015","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"10.1016\/j.joca.2026.06.011_bib17","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.bone.2005.08.007","article-title":"Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis","volume":"38","author":"Hayami","year":"2006","journal-title":"Bone"},{"key":"10.1016\/j.joca.2026.06.011_bib18","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.joca.2010.01.004","article-title":"In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model","volume":"18","author":"Intema","year":"2010","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2026.06.011_bib19","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1053\/jars.2002.36114","article-title":"Associated injuries in pediatric and adolescent anterior cruciate ligament tears: does a delay in treatment increase the risk of meniscal tear?","volume":"18","author":"Millett","year":"2002","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib20","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.arthro.2004.01.004","article-title":"Radial tears of the posterior horn of the medial meniscus","volume":"20","author":"Bin","year":"2004","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib21","article-title":"Medial meniscus posterior horn horizontal tears are associated with knee posteromedial impinging structures inducing shearing forces in patients with meniscus degeneration","volume":"0","author":"Lim","year":"2025","journal-title":"Cartilage"},{"key":"10.1016\/j.joca.2026.06.011_bib22","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.arthro.2009.11.002","article-title":"Cam impingement of the posterior femoral condyle in medial meniscal tears","volume":"26","author":"Suganuma","year":"2010","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib23","doi-asserted-by":"crossref","first-page":"9159","DOI":"10.1038\/s41598-022-13062-y","article-title":"Structural changes in the collagen network of joint tissues in late stages of murine OA","volume":"12","author":"Yoshioka","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2026.06.011_bib24","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0749-8063(05)80061-1","article-title":"Magnetic resonance imaging (MRI) and arthroscopy in the detection of meniscal degenerations: correlation of arthroscopy and MRI with histology findings","volume":"10","author":"Raunest","year":"1994","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib25","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1177\/03635465211064297","article-title":"Circumferential rim augmentation suture around the perimeniscal capsule decreases meniscal extrusion and progression of osteoarthritis in rabbit meniscus root tear model","volume":"50","author":"Park","year":"2022","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.joca.2026.06.011_bib26","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.joca.2011.05.008","article-title":"Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritis","volume":"19","author":"Pauli","year":"2011","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2026.06.011_bib27","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/jor.24846","article-title":"Synovial mesenchymal stem cells promote the meniscus repair in a novel pig meniscus injury model","volume":"39","author":"Ozeki","year":"2021","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.joca.2026.06.011_bib28","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.jos.2017.01.024","article-title":"Centralization of extruded medial meniscus delays cartilage degeneration in rats","volume":"22","author":"Ozeki","year":"2017","journal-title":"J. Orthop. Sci."},{"key":"10.1016\/j.joca.2026.06.011_bib29","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.joca.2015.02.008","article-title":"Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs","volume":"23","author":"Nakagawa","year":"2015","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2026.06.011_bib30","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/jor.23275","article-title":"Comparison of two models of post-traumatic osteoarthritis; temporal degradation of articular cartilage and menisci","volume":"35","author":"Fischenich","year":"2017","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.joca.2026.06.011_bib31","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1053\/joca.2000.0350","article-title":"Early changes in lapine menisci during osteoarthritis development: Part I: cellular and matrix alterations","volume":"9","author":"Hellio Le Graverand","year":"2001","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.joca.2026.06.011_bib32","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s00776-005-0916-6","article-title":"Histological and biochemical changes of experimental meniscus tear in the dog knee","volume":"10","author":"Nishida","year":"2005","journal-title":"J. Orthop. Sci."},{"key":"10.1016\/j.joca.2026.06.011_bib33","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.arthro.2016.09.027","article-title":"Complex medial meniscus tears are associated with a biconcave Medial Tibial Plateau","volume":"33","author":"Barber","year":"2017","journal-title":"Arthroscopy"},{"key":"10.1016\/j.joca.2026.06.011_bib34","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1177\/0363546503258880","article-title":"Effects of increasing tibial slope on the biomechanics of the knee","volume":"32","author":"Giffin","year":"2004","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.joca.2026.06.011_bib35","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1177\/0363546520917420","article-title":"Medial meniscal posterior horn tears are associated with increased posterior tibial slope: a case-control study","volume":"48","author":"Moon","year":"2020","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.joca.2026.06.011_bib36","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.1038\/s41598-021-83181-5","article-title":"Intra-substance meniscal changes and their clinical significance: a meta-analysis","volume":"11","author":"Ahmad","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.joca.2026.06.011_bib37","doi-asserted-by":"crossref","first-page":"516","DOI":"10.2214\/AJR.14.12969","article-title":"Pitfalls and pearls in MRI of the knee","volume":"203","author":"Mohankumar","year":"2014","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.joca.2026.06.011_bib38","doi-asserted-by":"crossref","DOI":"10.21276\/ijcmsr.2018.3.2.17","article-title":"MRI with arthroscopic correlation in meniscal injuries of knee","volume":"3","author":"Saseendran","year":"2018","journal-title":"Int. J. Contemp. Med. Surg. Radiol."},{"key":"10.1016\/j.joca.2026.06.011_bib39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1089\/ten.teb.2009.0428","article-title":"Translational models for studying meniscal repair and replacement: what they can and cannot tell us","volume":"16","author":"Arnoczky","year":"2010","journal-title":"Tissue Eng. Part. B Rev."},{"key":"10.1016\/j.joca.2026.06.011_bib40","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1002\/jor.20869","article-title":"Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair","volume":"27","author":"Chevrier","year":"2009","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.joca.2026.06.011_bib41","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1177\/0363546515605086","article-title":"The degeneration of meniscus roots is accompanied by fibrocartilage formation, which may precede meniscus root tears in osteoarthritic knees","volume":"43","author":"Park","year":"2015","journal-title":"Am. J. Sports Med."}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458426009532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458426009532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:12:02Z","timestamp":1791990722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458426009532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":41,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1063458426009532"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2026.06.011","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of an impingement induced, reversible degenerative meniscus tear animal model to analyze pathogenesis and potential recovery from meniscus degeneration","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2026.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}