{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T13:32:25Z","timestamp":1793367145074,"version":"4.5.0"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.joca.2026.10.008","type":"journal-article","created":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:42:41Z","timestamp":1792302161000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Knee arthroplasty is an effective treatment for people with overweight\/obesity and painful knees, but is this the endpoint we want for our patients?"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7033-8459","authenticated-orcid":false,"given":"Stephen P.","family":"Messier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10431","key":"10.1016\/j.joca.2026.10.008_bib1","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0140-6736(23)02750-2","article-title":"Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults","volume":"403","author":"Phelps","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.joca.2026.10.008_bib2","series-title":"Prevalence of Overweight, Obesity, And Severe Obesity Among Adults Aged 20 And Over: United States, 1960\u20131962 Through 2017\u20132018","author":"Fryar","year":"2020"},{"issue":"10258","key":"10.1016\/j.joca.2026.10.008_bib3","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"396","author":"GBD 2019 Diseases and Injuries Collaborators","year":"2020","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.joca.2026.10.008_bib4","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.joca.2019.06.011","article-title":"OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis","volume":"27","author":"Bannuru","year":"2019","journal-title":"Osteoarthr. Cartil."},{"issue":"10","key":"10.1016\/j.joca.2026.10.008_bib5","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1136\/ard.2010.142018","article-title":"Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial","volume":"70","author":"Bliddal","year":"2011","journal-title":"Ann. Rheum. Dis."},{"issue":"2","key":"10.1016\/j.joca.2026.10.008_bib6","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1056\/NEJMoa013259","article-title":"A controlled trial of arthroscopic surgery for osteoarthritis of the knee","volume":"347","author":"Moseley","year":"2002","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.joca.2026.10.008_bib7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/acr.22412","article-title":"Lifetime medical costs of knee osteoarthritis management in the United States: impact of extending indications for total knee arthroplasty","volume":"67","author":"Losina","year":"2015","journal-title":"Arthritis Care Res."},{"issue":"12","key":"10.1016\/j.joca.2026.10.008_bib8","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1001\/jama.2013.277669","article-title":"Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial","volume":"310","author":"Messier","year":"2013","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.joca.2026.10.008_bib9","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1002\/acr.24534","article-title":"\u201cIt\u2019s not my knee\u201d: understanding ongoing pain and discomfort after total knee replacement through re-embodiment","volume":"74","author":"Moore","year":"2022","journal-title":"Arthritis Care Res."},{"issue":"3","key":"10.1016\/j.joca.2026.10.008_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002761","article-title":"Cost-effectiveness of financial incentives for improving diet and health through Medicare and Medicaid: a microsimulation study","volume":"16","author":"Lee","year":"2019","journal-title":"PLoS Med."},{"issue":"1","key":"10.1016\/j.joca.2026.10.008_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.ocarto.2024.100563","article-title":"The PIKASO trial (Preventing Injured Knees from Osteoarthritis: Severity Outcomes): rationale and design features for a randomized controlled trial","volume":"7","author":"Jacobs","year":"2024","journal-title":"Osteoarthr. Cartil. Open"},{"issue":"1","key":"10.1016\/j.joca.2026.10.008_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ocarto.2023.100418","article-title":"The osteoarthritis prevention study (TOPS) \u2014 a randomized controlled trial of diet and exercise to prevent knee osteoarthritis: design and rationale","volume":"6","author":"Messier","year":"2024","journal-title":"Osteoarthr. Cartil. Open"},{"issue":"4","key":"10.1016\/j.joca.2026.10.008_bib13","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00003677-200510000-00008","article-title":"The role of mechanical loading in the onset and progression of osteoarthritis","volume":"33","author":"Griffin","year":"2005","journal-title":"Exerc. Sci. Rev."},{"key":"10.1016\/j.joca.2026.10.008_bib14","series-title":"Osteoarthritis Health Professional Training Manual","article-title":"Core components of best evidence OA care: management planning, education, supporting self-management and behavior change","author":"Mihalko","year":"2022"},{"issue":"9702","key":"10.1016\/j.joca.2026.10.008_bib15","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/S0140-6736(09)61457-4","article-title":"10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study","volume":"374","author":"Knowler","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.joca.2026.10.008_bib16","unstructured":"HEARTS quality: a policy framework to strengthen hypertension and cardiovascular risk management in primary healthcare \u2014 insights from HEARTS in the Americas \u2014 ClinicalKey, Accessed 24 August 2026. https:\/\/www.clinicalkey.com\/#!\/content\/playContent\/1-s2.0-S2667193X25003229?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2667193X25003229%3Fshowall%3Dtrue&referrer=https:%2F%2Fpubmed.ncbi.nlm.nih.gov%2F."}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458426010873?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458426010873?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:44:51Z","timestamp":1793364291000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458426010873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":16,"alternative-id":["S1063458426010873"],"URL":"https:\/\/doi.org\/10.1016\/j.joca.2026.10.008","relation":{},"ISSN":["1063-4584"],"issn-type":[{"value":"1063-4584","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Knee arthroplasty is an effective treatment for people with overweight\/obesity and painful knees, but is this the endpoint we want for our patients?","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2026.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.joca.2026.07.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}