{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:24:38Z","timestamp":1783441478556,"version":"3.54.6"},"reference-count":99,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Densitometry"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.jocd.2010.06.004","type":"journal-article","created":{"date-parts":[[2010,10,27]],"date-time":"2010-10-27T04:20:28Z","timestamp":1288153228000},"page":"324-334","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Management of Skeletal Health in Patients With Asymptomatic Primary Hyperparathyroidism"],"prefix":"10.1016","volume":"13","author":[{"given":"E. Michael","family":"Lewiecki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1365-2265.2007.02970.x","article-title":"Asymptomatic hyperparathyroidism\u2014need for multicentre studies","volume":"68","author":"Mihai","year":"2008","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib2","first-page":"40","article-title":"Evidence for a 7000-year-old case of primary hyperparathyroidism","volume":"293","author":"Zink","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.jocd.2010.06.004_bib3","series-title":"Festchrift Rudolf Virchow","article-title":"Die fibrose oder deformierende ostitis, die osteomalazie und die osteoplastische carzinose in ihren gegenseitigen beziehungen","author":"von Recklinghausen","year":"1891"},{"issue":"21","key":"10.1016\/j.jocd.2010.06.004_bib4","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1056\/NEJM196605262742105","article-title":"The study of hyperparathyroidism at the Massachusetts General Hospital","volume":"274","author":"Cope","year":"1966","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jocd.2010.06.004_bib5","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1097\/00000478-199609000-00010","article-title":"The glandulae parathyroideae of Ivar Sandstrom. Contributions from two continents","volume":"20","author":"Carney","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.jocd.2010.06.004_bib6","first-page":"245","article-title":"Klinisches und experimentelles zur frage lokalisierten und generalisierten ostitis fibrosa","volume":"143","author":"Mandl","year":"1926","journal-title":"Arch Klin Chir"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.amjoto.2005.11.004","article-title":"Brown tumors of the jaws associated with primary or secondary hyperparathyroidism. A clinical study and review of the literature","volume":"27","author":"Triantafillidou","year":"2006","journal-title":"Am J Otolaryngol"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib8","first-page":"950","article-title":"Brown tumors mimicking bone metastases","volume":"98","author":"Meydan","year":"2006","journal-title":"J Natl Med Assoc"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib9","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/0002-9343(75)90327-7","article-title":"Osteosclerosis in primary hyperparathyroidism","volume":"59","author":"Genant","year":"1975","journal-title":"Am J Med"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib10","first-page":"2036","article-title":"Evaluation and management of primary hyperparathyroidism","volume":"81","author":"Silverberg","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"10.1016\/j.jocd.2010.06.004_bib11","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1210\/jc.2006-2802","article-title":"Normocalcemic primary hyperparathyroidism: further characterization of a new clinical phenotype","volume":"92","author":"Lowe","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocd.2010.06.004_bib12","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1002\/jbmr.5650111021","article-title":"Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study","volume":"11","author":"Garnero","year":"1996","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib13","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/jbmr.5650100319","article-title":"Relations between histologic indices of bone formation: implications for the pathogenesis of spinal osteoporosis","volume":"10","author":"Parfitt","year":"1995","journal-title":"J Bone Miner Res"},{"issue":"12","key":"10.1016\/j.jocd.2010.06.004_bib14","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1172\/JCI27071","article-title":"Pathogenesis of osteoporosis: concepts, conflicts, and prospects","volume":"115","author":"Raisz","year":"2005","journal-title":"J Clin Invest"},{"issue":"8","key":"10.1016\/j.jocd.2010.06.004_bib15","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1359\/jbmr.1999.14.8.1404","article-title":"Biochemical markers of bone turnover and prediction of hip bone loss in older women: the study of osteoporotic fractures","volume":"14","author":"Bauer","year":"1999","journal-title":"J Bone Miner Res"},{"issue":"Suppl 6","key":"10.1016\/j.jocd.2010.06.004_bib16","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1007\/s001980070006","article-title":"Markers of bone turnover for the prediction of fracture risk","volume":"11","author":"Garnero","year":"2000","journal-title":"Osteoporos Int"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S8756-3282(97)00078-1","article-title":"Primary hyperparathyroidism: biochemical markers and bone mineral density at multiple skeletal sites in Danish patients","volume":"21","author":"Christiansen","year":"1997","journal-title":"Bone"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1046\/j.1365-2796.1998.00241.x","article-title":"Increased biochemical markers of bone formation and resorption in primary hyperparathyroidism with special reference to patients with mild disease","volume":"243","author":"Valdemarsson","year":"1998","journal-title":"J Intern Med"},{"issue":"7","key":"10.1016\/j.jocd.2010.06.004_bib19","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1007\/BF00311432","article-title":"Evaluation of bone loss and the serum markers of bone metabolism in patients with hyperparathyroidism","volume":"25","author":"Katagiri","year":"1995","journal-title":"Surg Today"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib20","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1210\/jcem-70-4-930","article-title":"The histomorphometry of bone in primary hyperparathyroidism: preservation of cancellous bone structure","volume":"70","author":"Parisien","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib21","first-page":"1562","article-title":"On the mechanism of cancellous bone preservation in postmenopausal women with mild primary hyperparathyroidism","volume":"84","author":"Dempster","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib22","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S8756-3282(00)00260-X","article-title":"Primary hyperparathyroidism: bone structure, balance, and remodeling before and 3 years after surgical treatment","volume":"26","author":"Steiniche","year":"2000","journal-title":"Bone"},{"issue":"9","key":"10.1016\/j.jocd.2010.06.004_bib23","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/jbmr.5650100917","article-title":"Bone structure in postmenopausal hyperparathyroid, osteoporotic, and normal women","volume":"10","author":"Parisien","year":"1995","journal-title":"J Bone Miner Res"},{"issue":"8","key":"10.1016\/j.jocd.2010.06.004_bib24","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jbmr.5650070808","article-title":"Maintenance of cancellous bone connectivity in primary hyperparathyroidism: trabecular strut analysis","volume":"7","author":"Parisien","year":"1992","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib25","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/8756-3282(86)90020-7","article-title":"Trabecular bone remodeling and balance in primary hyperparathyroidism","volume":"7","author":"Eriksen","year":"1986","journal-title":"Bone"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib26","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/jbmr.5650040302","article-title":"Skeletal disease in primary hyperparathyroidism","volume":"4","author":"Silverberg","year":"1989","journal-title":"J Bone Miner Res"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib27","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/8756-3282(92)90360-9","article-title":"Primary hyperparathyroidism: iliac crest trabecular bone volume, structure, remodeling, and balance evaluated by histomorphometric methods","volume":"13","author":"Christiansen","year":"1992","journal-title":"Bone"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib28","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0169-6009(08)80100-6","article-title":"Bone histomorphometry and serum concentrations of intact parathyroid hormone (PTH(1-84)) in patients with primary hyperparathyroidism","volume":"23","author":"van","year":"1993","journal-title":"Bone Miner"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib29","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00192633","article-title":"Trabecular bone structure in patients with primary hyperparathyroidism","volume":"426","author":"Vogel","year":"1995","journal-title":"Virchows Arch"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib30","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s007740050096","article-title":"Microstructure of the trabecula and cortex of iliac bone in primary hyperparathyroidism patients determined using histomorphometry and node-strut analysis","volume":"17","author":"Uchiyama","year":"1999","journal-title":"J Bone Miner Metab"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib31","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00002142-200210000-00002","article-title":"Bone microstructure in osteoporosis: transilial biopsy and histomorphometry","volume":"13","author":"Barger-Lux","year":"2002","journal-title":"Top Magn Reson Imaging"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib32","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S8756-3282(98)00068-4","article-title":"Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography","volume":"23","author":"Muller","year":"1998","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.bone.2007.03.020","article-title":"Preserved three-dimensional cancellous bone structure in mild primary hyperparathyroidism","volume":"41","author":"Dempster","year":"2007","journal-title":"Bone"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib34","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1359\/jbmr.070120","article-title":"New observations on bone quality in mild primary hyperparathyroidism as determined by quantitative backscattered electron imaging","volume":"22","author":"Roschger","year":"2007","journal-title":"J\u00a0Bone Miner Res"},{"issue":"Suppl 2","key":"10.1016\/j.jocd.2010.06.004_bib35","first-page":"N98","article-title":"Bone densitometry in asymptomatic primary hyperparathyroidism","volume":"17","author":"Miller","year":"2002","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jocd.2010.06.004_bib36","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1056\/NEJM199910213411701","article-title":"A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery","volume":"341","author":"Silverberg","year":"1999","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jocd.2010.06.004_bib37","doi-asserted-by":"crossref","first-page":"3462","DOI":"10.1210\/jc.2007-1215","article-title":"The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15-years","volume":"93","author":"Rubin","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib38","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1359\/JBMR.050910","article-title":"Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: an update on the changing epidemiology of the disease","volume":"21","author":"Wermers","year":"2006","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib39","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0889-8529(05)70145-6","article-title":"Natural history of primary hyperparathyroidism","volume":"29","author":"Silverberg","year":"2000","journal-title":"Endocrinol Metabol Clin North Am"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib40","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-2362.1988.tb01163.x","article-title":"Prevalence of hypercalcaemia in a health survey: a 14-year follow-up study of serum calcium values","volume":"18","author":"Palmer","year":"1988","journal-title":"Eur J Clin Invest"},{"issue":"7041","key":"10.1016\/j.jocd.2010.06.004_bib41","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1136\/bmj.312.7041.1254","article-title":"Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures","volume":"312","author":"Marshall","year":"1996","journal-title":"BMJ"},{"issue":"Suppl 5","key":"10.1016\/j.jocd.2010.06.004_bib42","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00198-003-1482-4","article-title":"Bone strength in primary hyperparathyroidism","volume":"14","author":"Bilezikian","year":"2003","journal-title":"Osteoporos Int"},{"issue":"10","key":"10.1016\/j.jocd.2010.06.004_bib43","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1359\/jbmr.2002.17.10.1741","article-title":"Parathyroid hormone and periosteal bone expansion","volume":"17","author":"Parfitt","year":"2002","journal-title":"J Bone Miner Res"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib44","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S8756-3282(98)00042-8","article-title":"Bone measurements in asymptomatic primary hyperparathyroidism","volume":"22","author":"Adami","year":"1998","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib45","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1359\/jbmr.2001.16.1.120","article-title":"Fracture site-specific deficits in bone size and volumetric density in men with spine or hip fractures","volume":"16","author":"Seeman","year":"2001","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jocd.2010.06.004_bib46","doi-asserted-by":"crossref","first-page":"959","DOI":"10.7326\/0003-4819-109-12-959","article-title":"Mild asymptomatic primary hyperparathyroidism is not a risk factor for vertebral fractures","volume":"109","author":"Wilson","year":"1988","journal-title":"Ann Intern Med"},{"issue":"10","key":"10.1016\/j.jocd.2010.06.004_bib47","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1359\/jbmr.1999.14.10.1700","article-title":"Primary hyperparathyroidism and the risk of fracture: a population-based study","volume":"14","author":"Khosla","year":"1999","journal-title":"J Bone Miner Res"},{"issue":"7","key":"10.1016\/j.jocd.2010.06.004_bib48","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1210\/jc.2008-2006","article-title":"Morphometric vertebral fractures in postmenopausal women with primary hyperparathyroidism","volume":"94","author":"Vignali","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"7261","key":"10.1016\/j.jocd.2010.06.004_bib49","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1136\/bmj.321.7261.598","article-title":"Cohort study of risk of fracture before and after surgery for primary hyperparathyroidism","volume":"321","author":"Vestergaard","year":"2000","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib50","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1046\/j.0954-6820.2003.01237.x","article-title":"Parathyroid surgery is associated with a decreased risk of hip and upper arm fractures in primary hyperparathyroidism: a controlled cohort study","volume":"255","author":"Vestergaard","year":"2004","journal-title":"J Intern Med"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib51","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1365-2796.1993.tb01017.x","article-title":"The risk of hip fractures in patients with primary hyperparathyroidism: a population-based cohort study with a follow-up of 19 years","volume":"234","author":"Larsson","year":"1993","journal-title":"J Intern Med"},{"issue":"Suppl 2","key":"10.1016\/j.jocd.2010.06.004_bib52","first-page":"N57","article-title":"Asymptomatic primary hyperparathyroidism: new issues and new questions\u2014bridging the past with the future","volume":"17","author":"Bilezikian","year":"2002","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib53","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1530\/eje.1.02225","article-title":"The risk of fractures in postmenopausal women with primary hyperparathyroidism","volume":"155","author":"De","year":"2006","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib54","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1210\/jc.2008-1760","article-title":"Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop","volume":"94","author":"Silverberg","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib55","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1210\/jc.2008-1758","article-title":"Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop","volume":"94","author":"Eastell","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"Suppl 2","key":"10.1016\/j.jocd.2010.06.004_bib56","first-page":"S97","article-title":"Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening: clinical course and considerations bearing on the need for surgical intervention","volume":"6","author":"Parfitt","year":"1991","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib57","doi-asserted-by":"crossref","first-page":"3800","DOI":"10.1210\/jc.2005-0784","article-title":"Postmenopausal osteoporosis and the detection of so-called secondary causes of low bone density","volume":"90","author":"Favus","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocd.2010.06.004_bib58","doi-asserted-by":"crossref","first-page":"4431","DOI":"10.1210\/jc.2002-020275","article-title":"Yield of laboratory testing to identify secondary contributors to osteoporosis in otherwise healthy women","volume":"87","author":"Tannenbaum","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib59","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0025-6196(11)62214-3","article-title":"Secondary causes of osteoporosis","volume":"77","author":"Fitzpatrick","year":"2002","journal-title":"Mayo Clin Proc"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib60","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00223-001-1048-4","article-title":"Secondary causes of osteoporosis in men","volume":"69","author":"Compston","year":"2001","journal-title":"Calcif Tissue Int"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib61","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1385\/JCD:2:1:79","article-title":"Causes of secondary osteoporosis","volume":"2","author":"Orlic","year":"1999","journal-title":"J\u00a0Clin Densitom"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib62","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0889-8529(05)70008-6","article-title":"Secondary osteoporosis\u2014diagnostic considerations","volume":"27","author":"Harper","year":"1998","journal-title":"Endocrinol Metabol Clin North Am"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib63","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1210\/jc.2008-1763","article-title":"Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the third international workshop","volume":"94","author":"Bilezikian","year":"2009","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib64","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1210\/jc.2008-1761","article-title":"Surgery for asymptomatic primary hyperparathyroidism: proceedings of the third international workshop","volume":"94","author":"Udelsman","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocd.2010.06.004_bib65","first-page":"N2","article-title":"Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century","volume":"17","author":"Bilezikian","year":"2002","journal-title":"J Bone Miner Res"},{"issue":"9","key":"10.1016\/j.jocd.2010.06.004_bib66","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1097\/01.hjh.0000179764.40701.36","article-title":"Serum parathyroid hormone as a predictor of increase in systolic blood pressure in men","volume":"23","author":"Jorde","year":"2005","journal-title":"J Hypertens"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib67","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/01.hjr.0000114706.27531.01","article-title":"Serum parathyroid hormone levels predict coronary heart disease: the Tromso Study","volume":"11","author":"Kamycheva","year":"2004","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib68","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/BF03324791","article-title":"Does elevated parathyroid hormone concentration predict cognitive decline in older people?","volume":"22","author":"Bjorkman","year":"2010","journal-title":"Aging Clin Exp Res"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib69","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1210\/jc.2003-031782","article-title":"Serum parathyroid hormone predicts time to fall independent of vitamin D status in a frail elderly population","volume":"89","author":"Sambrook","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib70","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1159\/000239757","article-title":"Parathyroid hormone as a mortality predictor in frail aged inpatients","volume":"55","author":"Bjorkman","year":"2009","journal-title":"Gerontology"},{"issue":"7414","key":"10.1016\/j.jocd.2010.06.004_bib71","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/bmj.327.7414.530","article-title":"Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism","volume":"327","author":"Vestergaard","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.jocd.2010.06.004_bib72","first-page":"729","article-title":"Increased bone mineral density after parathyroidectomy in primary hyperparathyroidism","volume":"80","author":"Silverberg","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jocd.2010.06.004_bib73","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/S8756-3282(99)00207-0","article-title":"Primary hyperparathyroidism: effect of parathyroidectomy on regional bone mineral density in Danish patients: a three-year follow-up study","volume":"25","author":"Christiansen","year":"1999","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib74","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1097\/00004424-198211000-00013","article-title":"Sequential changes in bone density before and after parathyroidectomy in primary hyperparathyroidism","volume":"17","author":"Leppla","year":"1982","journal-title":"Invest Radiol"},{"issue":"Suppl 2","key":"10.1016\/j.jocd.2010.06.004_bib75","first-page":"N75","article-title":"Role of vitamin D and calcium nutrition in disease expression and parathyroid tumor growth in primary hyperparathyroidism: a global perspective","volume":"17","author":"Rao","year":"2002","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib76","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1365-2265.1995.tb02043.x","article-title":"Vitamin D status in primary hyperparathyroidism in India","volume":"43","author":"Harinarayan","year":"1995","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib77","first-page":"1054","article-title":"Effect of vitamin D nutrition on parathyroid adenoma weight: pathogenetic and clinical implications","volume":"85","author":"Rao","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.jocd.2010.06.004_bib78","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0002-9343(99)00294-6","article-title":"The effects of vitamin D insufficiency in patients with primary hyperparathyroidism","volume":"107","author":"Silverberg","year":"1999","journal-title":"Am J Med"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib79","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jc.2002-020890","article-title":"Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism","volume":"88","author":"Chow","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocd.2010.06.004_bib80","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1359\/jbmr.2001.16.1.113","article-title":"Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism","volume":"16","author":"Rossini","year":"2001","journal-title":"J Bone Miner Res"},{"issue":"7","key":"10.1016\/j.jocd.2010.06.004_bib81","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1210\/jc.2003-030908","article-title":"Alendronate in primary hyperparathyroidism: a double-blind, randomized, placebo-controlled trial","volume":"89","author":"Khan","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib82","doi-asserted-by":"crossref","first-page":"23","DOI":"10.7326\/0003-4819-95-1-23","article-title":"Effects of dichloromethylene diphosphonate on serum and urinary calcium in primary hyperparathyroidism","volume":"95","author":"Shane","year":"1981","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib83","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000048935","article-title":"A strategy for the management of elderly women with primary hyperparathyroidism: a comparison of etidronate therapy with parathyroidectomy","volume":"48","author":"Horiuchi","year":"2002","journal-title":"Gerontology"},{"issue":"Suppl 1","key":"10.1016\/j.jocd.2010.06.004_bib84","first-page":"S69","article-title":"Clodronate in the medical management of hyperparathyroidism","volume":"8","author":"Hamdy","year":"1987","journal-title":"Bone"},{"key":"10.1016\/j.jocd.2010.06.004_bib85","first-page":"1067","article-title":"Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism with risedronate","volume":"77","author":"Reasner","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"10.1016\/j.jocd.2010.06.004_bib86","doi-asserted-by":"crossref","first-page":"705","DOI":"10.4158\/EP08178.ORR","article-title":"Alendronate therapy in men with primary hyperparathyroidism","volume":"15","author":"Khan","year":"2009","journal-title":"Endocr Pract"},{"key":"10.1016\/j.jocd.2010.06.004_bib87","doi-asserted-by":"crossref","first-page":"633","DOI":"10.7326\/0003-4819-100-5-633","article-title":"Conjugated estrogens in the treatment of postmenopausal women with hyperparathyroidism","volume":"100","author":"Marcus","year":"1984","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jocd.2010.06.004_bib88","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1056\/NEJM198606053142304","article-title":"Ethinyl estradiol and norethindrone in the treatment of primary hyperparathyroidism in postmenopausal women","volume":"314","author":"Selby","year":"1986","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib89","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/jbmr.5650090410","article-title":"Effects of mild asymptomatic primary hyperparathyroidism on bone mass in women with and without estrogen replacement therapy","volume":"9","author":"McDermott","year":"1994","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jocd.2010.06.004_bib90","doi-asserted-by":"crossref","first-page":"360","DOI":"10.7326\/0003-4819-125-5-199609010-00002","article-title":"Effect of hormone replacement therapy on bone mineral density in postmenopausal women with mild primary hyperparathyroidism\u2014a randomized, controlled trial","volume":"125","author":"Grey","year":"1996","journal-title":"Ann Intern Med"},{"issue":"14","key":"10.1016\/j.jocd.2010.06.004_bib91","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1001\/archinte.160.14.2161","article-title":"Effects of hormone replacement therapy on bone mineral density in postmenopausal women with primary hyperparathyroidism\u2014four-year follow-up and comparison with healthy postmenopausal women","volume":"160","author":"Orr-Walker","year":"2000","journal-title":"Arch Intern Med"},{"issue":"13","key":"10.1016\/j.jocd.2010.06.004_bib92","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1001\/jama.290.13.1729","article-title":"Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial","volume":"290","author":"Cauley","year":"2003","journal-title":"JAMA"},{"issue":"14","key":"10.1016\/j.jocd.2010.06.004_bib93","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1001\/jama.291.14.1701","article-title":"Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial","volume":"291","author":"Anderson","year":"2004","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.jocd.2010.06.004_bib94","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1210\/jc.2002-020667","article-title":"Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism","volume":"88","author":"Rubin","year":"2003","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib95","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1359\/jbmr.2001.16.1.189","article-title":"Clinical vignette\u2014raloxifene reverses bone loss in postmenopausal women with mild asymptomatic primary hyperparathyroidism","volume":"16","author":"Zanchetta","year":"2001","journal-title":"J Bone Miner Res"},{"issue":"1","key":"10.1016\/j.jocd.2010.06.004_bib96","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1210\/jc.2004-0842","article-title":"Cinacalcet hydrochloride maintains long-term normocalcemia in patients with primary hyperparathyroidism","volume":"90","author":"Peacock","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"10.1016\/j.jocd.2010.06.004_bib97","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1210\/jc.2008-2640","article-title":"Cinacalcet reduces serum calcium concentrations in patients with intractable primary hyperparathyroidism","volume":"94","author":"Marcocci","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.jocd.2010.06.004_bib98","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1210\/jc.2009-2384","article-title":"Skeletal effects of interventions in mild primary hyperparathyroidism: a meta-analysis","volume":"95","author":"Sankaran","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.jocd.2010.06.004_bib99","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1210\/jc.2008-1762","article-title":"Medical management of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop","volume":"94","author":"Khan","year":"2009","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Journal of Clinical Densitometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094695010002015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094695010002015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T21:36:23Z","timestamp":1761082583000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094695010002015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":99,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S1094695010002015"],"URL":"https:\/\/doi.org\/10.1016\/j.jocd.2010.06.004","relation":{},"ISSN":["1094-6950"],"issn-type":[{"value":"1094-6950","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of Skeletal Health in Patients With Asymptomatic Primary Hyperparathyroidism","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Densitometry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocd.2010.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}