{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:12:10Z","timestamp":1759191130282},"reference-count":34,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.jocn.2006.05.017","type":"journal-article","created":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T11:58:18Z","timestamp":1180526298000},"page":"650-657","source":"Crossref","is-referenced-by-count":5,"title":["Endothelin-1 and cerebral blood flow in a porcine model"],"prefix":"10.1016","volume":"14","author":[{"given":"Dirk","family":"Henze","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Menzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Soukup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Scharf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carsten","family":"Holz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"N\u00e9meth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Hanisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Clausen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2006.05.017_bib1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0165-6147(92)90118-P","article-title":"Neuroendocrine actions of endothelins","volume":"13","author":"Stojilkovic","year":"1992","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jocn.2006.05.017_bib2","first-page":"1","article-title":"Biochemical and functional characterization of endothelin peptides with special reference to vascular effects","volume":"602","author":"Hemsen","year":"1991","journal-title":"Acta Physiol Scand Suppl"},{"key":"10.1016\/j.jocn.2006.05.017_bib3","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0014-2999(95)00070-2","article-title":"The role of endothelin and nitric oxide in modulation of normal and spastic cerebral vascular tone in the dog","volume":"277","author":"Hirose","year":"1995","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jocn.2006.05.017_bib4","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1073\/pnas.86.8.2863","article-title":"The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes","volume":"86","author":"Inoue","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.05.017_bib5","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1073\/pnas.88.8.3185","article-title":"Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor","volume":"88","author":"Lin","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.05.017_bib6","doi-asserted-by":"crossref","first-page":"7443","DOI":"10.1073\/pnas.88.16.7443","article-title":"Design and synthesis of a specific endothelin 1 antagonist: effects on pulmonary vasoconstriction","volume":"88","author":"Spinella","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.05.017_bib7","doi-asserted-by":"crossref","first-page":"9797","DOI":"10.1073\/pnas.85.24.9797","article-title":"Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor","volume":"85","author":"De Nucci","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.05.017_bib8","doi-asserted-by":"crossref","first-page":"6964","DOI":"10.1073\/pnas.85.18.6964","article-title":"Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide","volume":"85","author":"Yanagisawa","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.05.017_bib9","doi-asserted-by":"crossref","first-page":"23251","DOI":"10.1016\/S0021-9258(18)54489-6","article-title":"Stimulation of endothelin-1 gene expression by insulin in endothelial cells","volume":"266","author":"Oliver","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jocn.2006.05.017_bib10","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1161\/01.RES.70.6.1191","article-title":"Oxidized low density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium","volume":"70","author":"Boulanger","year":"1992","journal-title":"Circ Res"},{"key":"10.1016\/j.jocn.2006.05.017_bib11","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0006-291X(89)92679-X","article-title":"Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells","volume":"161","author":"Yoshizumi","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jocn.2006.05.017_bib12","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1056\/NEJM199508103330607","article-title":"Endothelins","volume":"333","author":"Levin","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jocn.2006.05.017_bib13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1203\/00006450-199808000-00004","article-title":"Endothelial factors and autoregulation during pressure changes in isolated newborn piglet cerebral arteries","volume":"44","author":"Martinez-Orgado","year":"1998","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jocn.2006.05.017_bib14","doi-asserted-by":"crossref","first-page":"C300","DOI":"10.1152\/ajpcell.1999.276.2.C300","article-title":"Regulation of ET-1 biosynthesis in cerebral microvascular endothelial cells by vasoactive agents and PKC","volume":"276","author":"Yakubu","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jocn.2006.05.017_bib15","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1161\/01.STR.29.1.175","article-title":"Control of vascular tone by endogenous endothelin-1 in human pial arteries","volume":"29","author":"Thorin","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2006.05.017_bib16","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1007\/s001340051058","article-title":"The role of endothelin-1 in pressure autoregulation of cerebral blood flow in rats","volume":"25","author":"Mascia","year":"1999","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jocn.2006.05.017_bib17","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1152\/ajplegacy.1971.221.6.1629","article-title":"Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection","volume":"221","author":"Oldendorf","year":"1971","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jocn.2006.05.017_bib18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/00000542-200501000-00010","article-title":"The effect of esmolol on cerebral blood flow, cerebral vasoreactivity, and cognitive performance: a functional magnetic resonance imaging study","volume":"102","author":"Heinke","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jocn.2006.05.017_bib19","first-page":"281","article-title":"Endothelins: A brief review","volume":"29","author":"Balakrishnan","year":"1997","journal-title":"Indian J Pharmacol"},{"key":"10.1016\/j.jocn.2006.05.017_bib20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1172\/JCI116604","article-title":"Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia","volume":"92","author":"Kourembanas","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jocn.2006.05.017_bib21","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/0165-6147(93)90031-E","article-title":"Endothelins\u2013from receptors to medicine","volume":"14","author":"Miller","year":"1993","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jocn.2006.05.017_bib22","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/348732a0","article-title":"Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor","volume":"348","author":"Sakurai","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.jocn.2006.05.017_bib23","doi-asserted-by":"crossref","first-page":"19126","DOI":"10.1016\/S0021-9258(17)46743-3","article-title":"Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores","volume":"268","author":"Karne","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jocn.2006.05.017_bib24","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/sj.bjp.0704838","article-title":"Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B\/1D receptors during organ culture in rat basilar artery","volume":"137","author":"Hansen-Schwartz","year":"2002","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jocn.2006.05.017_bib25","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1161\/01.STR.0000028183.04277.32","article-title":"Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat","volume":"33","author":"Stenman","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2006.05.017_bib26","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1139\/y94-137","article-title":"Plasma endothelin-1dothelin-1 response to acute hypotension induced by vasodilating agents","volume":"72","author":"Cernacek","year":"1994","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jocn.2006.05.017_bib27","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1172\/JCI115367","article-title":"Hypoxia induces endothelin gene expression and secretion in cultured human endothelium","volume":"88","author":"Kourembanas","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jocn.2006.05.017_bib28","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1161\/01.HYP.18.3.304","article-title":"Endothelin-3 regulates endothelin-1 production in cultured human endothelial cells","volume":"18","author":"Yokokawa","year":"1991","journal-title":"Hypertension"},{"key":"10.1016\/j.jocn.2006.05.017_bib29","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/0895-7061(96)00019-2","article-title":"Neither physical exercise nor alpha 1- and beta-adrenergic blockade affect plasma endothelin concentrations","volume":"9","author":"Cosenzi","year":"1996","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jocn.2006.05.017_bib30","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0014-2999(92)90108-G","article-title":"Endothelin-1 enhances vascular permeability in conscious rats: role of thromboxane A2","volume":"214","author":"Sirois","year":"1992","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jocn.2006.05.017_bib31","doi-asserted-by":"crossref","first-page":"859","DOI":"10.3171\/jns.1997.86.5.0859","article-title":"Effects of intraluminal or extraluminal endothelin on perfused rabbit basilar arteries","volume":"86","author":"Kazuki","year":"1997","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2006.05.017_bib32","first-page":"47","article-title":"Levels of endothelins in plasma of patients with variant angina","volume":"92","author":"Salomon","year":"1994","journal-title":"Pol Arch Med Wewn"},{"key":"10.1016\/j.jocn.2006.05.017_bib33","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1161\/hs0901.94259","article-title":"Protective effect of endothelin type A receptor antagonist on brain edema and injury after transient middle cerebral artery occlusion in rats","volume":"32","author":"Matsuo","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2006.05.017_bib34","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1179\/016164101101198479","article-title":"Acute alterations of endothelin-1 and iNOS expression and control of the brain microcirculation after head trauma","volume":"23","author":"Petrov","year":"2001","journal-title":"Neurol Res"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586806004115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586806004115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T10:04:16Z","timestamp":1628935456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586806004115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0967586806004115"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2006.05.017","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}