{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:10:26Z","timestamp":1790104226009,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.jocn.2006.08.008","type":"journal-article","created":{"date-parts":[[2008,1,10]],"date-time":"2008-01-10T00:01:39Z","timestamp":1199923299000},"page":"1089-1098","source":"Crossref","is-referenced-by-count":121,"title":["Post-injury regeneration in rat sciatic nerve facilitated by neurotrophic factors secreted by amniotic fluid mesenchymal stem cells"],"prefix":"10.1016","volume":"14","author":[{"given":"Hung-Chuan","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Chou","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Jung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Zhen","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Wen","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dar-Yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hong","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Peng","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2006.08.008_bib1","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1097\/00006534-199392050-00020","article-title":"Immunocytochemistry of skeletal muscle basal lamina grafts in nerve regeneration","volume":"92","author":"Bryan","year":"1993","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jocn.2006.08.008_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-2007-1006637","article-title":"Sleeve insertion and collagen coating improves nerve regeneration through vein conduit","volume":"9","author":"Wang","year":"1993","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.jocn.2006.08.008_bib3","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1002\/mus.880130904","article-title":"Enhancement of peripheral nerve regeneration","volume":"13","author":"Seckel","year":"1990","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jocn.2006.08.008_bib4","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/jnr.490080208","article-title":"Nerve growth factors, laminin, and fibronection promote neurite growth in human fetal sensory ganglia cultures","volume":"8","author":"Baron-Van Evercoren","year":"1982","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/micr.1920100112","article-title":"Tubulation for peripheral nerve gap: its history and possibility","volume":"10","author":"Suematsu","year":"1989","journal-title":"Microsurgery"},{"key":"10.1016\/j.jocn.2006.08.008_bib6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/17453678709146461","article-title":"Nerve regeneration and repair: a review","volume":"58","author":"Lundborg","year":"1987","journal-title":"Acta Orthop Scand"},{"key":"10.1016\/j.jocn.2006.08.008_bib7","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1055\/s-2007-1006604","article-title":"Trophism, tropism, and specificity in nerve regeneration","volume":"10","author":"Lundborg","year":"1994","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.jocn.2006.08.008_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0168-0102(96)01042-5","article-title":"Peripheral nerve regeneration","volume":"25","author":"Ide","year":"1996","journal-title":"Neurosci Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib9","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/(SICI)1098-2752(1998)18:7<397::AID-MICR2>3.0.CO;2-F","article-title":"Schwann cells, neurotrophic factors, and peripheral nerve regeneration","volume":"18","author":"Frostick","year":"1998","journal-title":"Microsurgery"},{"key":"10.1016\/j.jocn.2006.08.008_bib10","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/S0006-8993(01)02395-2","article-title":"Glia cell line-derived neurotrophic factors enhances axon regeneration following sciatic nerve transection in adult rats","volume":"902","author":"Chen","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib11","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0014-4886(03)00041-4","article-title":"Repair of peripheral nerve transection with fibrin sealant containing neurotrophic factors","volume":"181","author":"Jubran","year":"2003","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jocn.2006.08.008_bib12","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1046\/j.1460-9568.2002.01892.x","article-title":"GDNF and NGF released by the synthetic guidance channels support sciatic nerve regeneration across a long gap","volume":"15","author":"Fine","year":"2002","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.jocn.2006.08.008_bib13","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1001\/archotol.124.7.761","article-title":"Repair with collagen tubules linked with brain-derived neurotrophic factor and ciliary neurotrophic factors in a rat sciatic nerve injured model","volume":"124","author":"Ho","year":"1998","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jocn.2006.08.008_bib14","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/363350a0","article-title":"Potentiation of developing neuromuscular synapses by the neurotrophin NT-3 and BDNF","volume":"363","author":"Lohof","year":"1993","journal-title":"Lett Nature"},{"key":"10.1016\/j.jocn.2006.08.008_bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0006-8993(03)02539-3","article-title":"Transplanted neuronal progenitor cells in a peripheral nerve gap promote nerve repair","volume":"4","author":"Murakami","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib16","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1097\/00001756-199904060-00035","article-title":"Olfactory bulb ensheathing cells enhance peripheral nerve regeneration","volume":"10","author":"Verdu","year":"1999","journal-title":"Neuroreport"},{"key":"10.1016\/j.jocn.2006.08.008_bib17","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3171\/jns.2004.101.5.0806","article-title":"Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats","volume":"101","author":"Mimura","year":"2004","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2006.08.008_bib18","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ymthe.2004.09.020","article-title":"Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model","volume":"11","author":"Kurozumi","year":"2005","journal-title":"Mol Ther"},{"key":"10.1016\/j.jocn.2006.08.008_bib19","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3171\/jns.2005.102.1.0080","article-title":"Early transplantation of an encapsulated glia cell line-derived neurotrophic factors-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease","volume":"102","author":"Yasuhara","year":"2005","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2006.08.008_bib20","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/humrep\/deh279","article-title":"Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol","volume":"19","author":"Tsia","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jocn.2006.08.008_bib21","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1182\/blood-2003-04-1291","article-title":"Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation","volume":"102","author":"In\u2019tAnker","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.jocn.2006.08.008_bib22","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/1097-4547(20001115)62:4<585::AID-JNR13>3.0.CO;2-U","article-title":"Neurotrophic function of conditioned medium from human amniotic epithelial cells","volume":"62","author":"Siako","year":"2000","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib23","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jocn.2005.06.007","article-title":"Enhanced regeneration in injured sciatic nerve by human amniotic mesenchymal stem cells","volume":"13","author":"Pan","year":"2006","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.jocn.2006.08.008_bib24","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1002\/mus.10374","article-title":"Ankle kinematics to evaluate functional recovery in crushed rat sciatic nerve","volume":"27","author":"Varejao","year":"2003","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jocn.2006.08.008_bib25","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00006534-198901000-00024","article-title":"Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesion in rat","volume":"83","author":"Bain","year":"1989","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jocn.2006.08.008_bib26","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00000637-198311000-00007","article-title":"Fascicular tubulization: a cellular approach to peripheral nerve repair","volume":"11","author":"Rosen","year":"1983","journal-title":"Ann Plasty Surg"},{"key":"10.1016\/j.jocn.2006.08.008_bib27","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0197-0186(96)00071-X","article-title":"Neutrotrophins and their receptors in nerve injury and repair","volume":"30","author":"Ebadi","year":"1997","journal-title":"Neurochem Int"},{"key":"10.1016\/j.jocn.2006.08.008_bib28","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1085-9489.2005.10105.x","article-title":"Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes","volume":"10","author":"Ahmed","year":"2005","journal-title":"J Periph Nerv Sys"},{"key":"10.1016\/j.jocn.2006.08.008_bib29","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0030-6665(20)30465-5","article-title":"Nerve wound healing: an overview","volume":"28","author":"Wong","year":"1995","journal-title":"Otolaryngol Clin N Am"},{"key":"10.1016\/j.jocn.2006.08.008_bib30","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0163-7258(94)00059-C","article-title":"The regulation of nerve growth factor synthesis and delivery to peripheral neurons","volume":"65","author":"Rush","year":"1995","journal-title":"Pharmacol Ther"},{"issue":"suppl","key":"10.1016\/j.jocn.2006.08.008_bib31","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1242\/jcs.1991.Supplement_15.14","article-title":"Effect of ciliary neutrotrophic factor (CNTF) on motoneurone survival","volume":"15","author":"Sendtner","year":"1991","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jocn.2006.08.008_bib32","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0896-6273(92)90168-D","article-title":"Regulation of ciliary neurotrophic factors expression in myelin-related Schwann cells in vivo","volume":"9","author":"Friedman","year":"1992","journal-title":"Neuron"},{"key":"10.1016\/j.jocn.2006.08.008_bib33","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/jnr.490310124","article-title":"Peripheral nerve injury down-regualted CNTF expression in adult rat sciatic nerves","volume":"31","author":"Rabinovsky","year":"1992","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jocn.2006.08.008_bib34","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1083\/jcb.123.2.455","article-title":"Differential expression of mRNA for neurotrophins and their receptors after axotomy of the scitiac nerve","volume":"123","author":"Funakoshi","year":"1993","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jocn.2006.08.008_bib35","first-page":"226","article-title":"Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism","volume":"463","author":"Pluchino","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.jocn.2006.08.008_bib36","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1042\/CS20040276","article-title":"Neural stem cells and cell replacement therapy: making the right cells","volume":"108","author":"Bithell","year":"2005","journal-title":"Clin Sci"},{"key":"10.1016\/j.jocn.2006.08.008_bib37","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1177\/096368970000900214","article-title":"Tansplantation options for therapeutic CNS remyelination","volume":"9","author":"Blakemore","year":"2000","journal-title":"Cell Transplant"},{"key":"10.1016\/j.jocn.2006.08.008_bib38","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/295325a0","article-title":"Expression of HLA antigen \u03b22-microglobulin and enzymes by human amniotic epithelial cells","volume":"295","author":"Adinolfi","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.jocn.2006.08.008_bib39","doi-asserted-by":"crossref","first-page":"9864","DOI":"10.1073\/pnas.142298299","article-title":"Characterization of the expression of MHC protein in human embryonic stem cells","volume":"99","author":"Drukker","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jocn.2006.08.008_bib40","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3171\/jns.2003.98.2.0371","article-title":"Effects of human amniotic fluid on peripheral nerve scarring and regeneration in rats","volume":"98","author":"Ozgenei","year":"2003","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2006.08.008_bib41","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.expneurol.2005.12.015","article-title":"In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells","volume":"198","author":"Aquino","year":"2006","journal-title":"Exper Neurol"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586806006394?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586806006394?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T10:51:28Z","timestamp":1630493488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586806006394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":41,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0967586806006394"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2006.08.008","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}