{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:44:43Z","timestamp":1774867483831,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","content-domain":{"domain":["jocn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.jocn.2013.04.025","type":"journal-article","created":{"date-parts":[[2013,10,19]],"date-time":"2013-10-19T00:15:46Z","timestamp":1382141746000},"page":"451-455","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Paraoxonase and arylesterase activity and total oxidative\/anti-oxidative status in patients with idiopathic Parkinson\u2019s disease"],"prefix":"10.1016","volume":"21","author":[{"given":"Aynur","family":"Kirbas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan","family":"Kirbas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Medine Cumhur","family":"Cure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Tufekci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2013.04.025_b0005","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1159\/000323265","article-title":"Serological profiles of urata, paraoxonase-1, ferritin and lipid in parkinson\u2019s diseases changes linked to diseases progression","volume":"8","author":"Ikeda","year":"2011","journal-title":"Neurodegener Dis"},{"key":"10.1016\/j.jocn.2013.04.025_b0010","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s11064-008-9656-2","article-title":"Oxidative and inflammatory pathways in parkinson\u2019s disease","volume":"34","author":"Miller","year":"2009","journal-title":"Neurochem Res"},{"key":"10.1016\/j.jocn.2013.04.025_b0015","doi-asserted-by":"crossref","unstructured":"Shukla V, Mishra SK, Pant HC. Oxidative Stress in Neurodegeneration. Advances in Pharmacological Sciences 2011;2011:572634.","DOI":"10.1155\/2011\/572634"},{"key":"10.1016\/j.jocn.2013.04.025_b0020","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/j.expneurol.2004.08.021","article-title":"Ubiquitin-proteasome system and Parkinson\u2019s diseases","volume":"191","author":"Betarbet","year":"2005","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jocn.2013.04.025_b0025","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2174\/156720506778249515","article-title":"Oxidative stress: apoptosis in neuronal injury","volume":"3","author":"Loh","year":"2006","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.jocn.2013.04.025_b0030","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1179\/135100004225004814","article-title":"Understanding the association between dietary anti-oxidants redox status and disease: is the total antioxidant capacity the right tool?","volume":"9","author":"Serafini","year":"2004","journal-title":"Redox Rep"},{"key":"10.1016\/j.jocn.2013.04.025_b0035","doi-asserted-by":"crossref","first-page":"982794","DOI":"10.1155\/2012\/982794","article-title":"Reactive oxygen species in skeletal muscle signaling","volume":"2012","author":"Barbieri","year":"2012","journal-title":"J Signal Transduct"},{"key":"10.1016\/j.jocn.2013.04.025_b0040","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1089\/ars.2006.8.1997","article-title":"Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders","volume":"8","author":"Mattson","year":"2006","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.jocn.2013.04.025_b0045","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.clinbiochem.2005.08.008","article-title":"A new automated colorimetric method for measuring total oxidant status","volume":"38","author":"Erel","year":"2005","journal-title":"Clin Biochem"},{"key":"10.1016\/j.jocn.2013.04.025_b0050","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.clinbiochem.2003.10.014","article-title":"A novel automated method to measure total anti-oxidant response against potent free radical reactions","volume":"37","author":"Erel","year":"2004","journal-title":"Clin Biochem"},{"key":"10.1016\/j.jocn.2013.04.025_b0055","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1002\/mds.10172","article-title":"Further evidence for an association of the Paraoxonase 1 (PON1) Met-54 allele with Parkinson\u2019s disease","volume":"17","author":"Carmine","year":"2002","journal-title":"Mov Disord"},{"key":"10.1016\/j.jocn.2013.04.025_b0060","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.taap.2011.08.009","article-title":"Role of paraoxonase 1(PON 1) in organophosphate metabolism: implications in neurodegenerative diseases","volume":"256","author":"Androutsopoulos","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.jocn.2013.04.025_b0065","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1089\/ars.2010.3774","article-title":"The humanparaoxonase gene cluster as a target in the treatment of atherosclerosis","volume":"16","author":"She","year":"2012","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.jocn.2013.04.025_b0070","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.atherosclerosis.2010.08.076","article-title":"The three-gene paraoxonase family: physiologic roles, actions and regulat\u0131on","volume":"214","author":"Pr\u00e9court","year":"2011","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jocn.2013.04.025_b0075","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0022-510X(01)00439-7","article-title":"Paraoxonase 1 Met-Leu54 polymorphism is associated with Parkinson\u2019s disease","volume":"184","author":"Akhmedova","year":"2001","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jocn.2013.04.025_b0080","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1002\/1531-8257(200011)15:6<1265::AID-MDS1034>3.0.CO;2-0","article-title":"No association between paraoxonase 1 (PON1) gene polymorphisms and susceptibility to Parkinson\u2019s disease in a Chinese population","volume":"15","author":"Wang","year":"2000","journal-title":"Mov Disord"},{"issue":"suppl","key":"10.1016\/j.jocn.2013.04.025_b0145","first-page":"165","article-title":"Parkinson\u2019s Disease Society Brain Bank, London: overview and research","volume":"39","author":"Daniel","year":"1993","journal-title":"J Neural Transm."},{"key":"10.1016\/j.jocn.2013.04.025_b0090","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0090-9556(25)07065-5","article-title":"Purification of human serum paraoxonase\/arylesterase. Evidence for one esterase catalyzing both activities","volume":"19","author":"Gan","year":"1991","journal-title":"Drug Metab Dispos"},{"key":"10.1016\/j.jocn.2013.04.025_b0095","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.exger.2003.08.001","article-title":"Study of factors influencing the decreased HDL associated PON1 activity with aging","volume":"39","author":"Seres","year":"2004","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.jocn.2013.04.025_b0100","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s007020070046","article-title":"Paraoxonase polymorphisms, pesticide exposure and Parkinson\u2019s disease in a Caucasian population","volume":"107","author":"Taylor","year":"2000","journal-title":"J Neural Transm"},{"key":"10.1016\/j.jocn.2013.04.025_b0105","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/0014-5793(91)80962-3","article-title":"Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein","volume":"286","author":"Mackness","year":"1991","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jocn.2013.04.025_b0110","first-page":"31","article-title":"Processes of free radical lipid peroxidation with a particular regard to the role of paraoxonase -1 in the pathogenesis of multiple sclerosis","volume":"64","author":"Berbecki","year":"2011","journal-title":"Wiad Lek"},{"key":"10.1016\/j.jocn.2013.04.025_b0115","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1212\/01.wnl.0000312511.62699.a8","article-title":"Total cholesterol and the risk of Parkinson disease","volume":"70","author":"Hu","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.jocn.2013.04.025_b0120","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1093\/aje\/kwj283","article-title":"Serum cholesterol levels and the risk of Parkinson\u2019s disease","volume":"164","author":"De Lau","year":"2006","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jocn.2013.04.025_b0125","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/EDE.0b013e3181c15ec6","article-title":"Paraoxonase 1, agricultural organophosphate exposure, and Parkinson\u2019s diseases","volume":"21","author":"Manthripragada","year":"2010","journal-title":"Epidemiology"},{"key":"10.1016\/j.jocn.2013.04.025_b0130","first-page":"55","article-title":"Pesticides exposure and genetic polymorphisms of paraoxonase in the susceptibility Parkinson\u2019s disease","volume":"14","author":"Fong","year":"2005","journal-title":"Acta Neurol Taiwan"},{"key":"10.1016\/j.jocn.2013.04.025_b0135","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cbi.2010.03.033","article-title":"Human PON1, a biomarker of risk of diseases and exposure","volume":"187","author":"Furlong","year":"2010","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.jocn.2013.04.025_b0140","doi-asserted-by":"crossref","first-page":"204.e13-5","DOI":"10.1016\/j.neurobiolaging.2010.08.010","article-title":"Paraoxonase 1 polymorphisms in Alzheimer\u2019s diseases, Parkinson\u2019s disease, and AD-PD spectrum diseases","volume":"33","author":"Wingo","year":"2012","journal-title":"Neurobiol Aging"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586813003585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586813003585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T17:35:00Z","timestamp":1746034500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586813003585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0967586813003585"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2013.04.025","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Paraoxonase and arylesterase activity and total oxidative\/anti-oxidative status in patients with idiopathic Parkinson\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2013.04.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}