{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:01:18Z","timestamp":1791241278202,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jocn-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.jocn.2017.01.022","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T22:30:19Z","timestamp":1486765819000},"page":"155-163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Melatonin and cortisol secretion profile in patients with pineal cyst before and after pineal cyst resection"],"prefix":"10.1016","volume":"39","author":[{"given":"Martin","family":"M\u00e1jovsk\u00fd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"\u0158ez\u00e1\u010dov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"Sumov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Posp\u00ed\u0161ilov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Netuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ond\u0159ej","family":"Brad\u00e1\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladim\u00edr","family":"Bene\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2017.01.022_b0005","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0006-8993(79)90848-5","article-title":"Pineal N-acetyltransferase and hydroxyindole-O-methyltransferase: control by the retinohypothalamic tract and the suprachiasmatic nucleus","volume":"174","author":"Klein","year":"1979","journal-title":"Brain Res"},{"issue":"Suppl 1","key":"10.1016\/j.jocn.2017.01.022_b0010","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.33549\/physiolres.935377","article-title":"Hormones, subjective night and season of the year","volume":"49","author":"Illnerov\u00e1","year":"2000","journal-title":"Physiol Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0015","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neuchi.2015.03.002","article-title":"Melatonin: physiological effects in humans","volume":"61","author":"Claustrat","year":"2015","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.jocn.2017.01.022_b0020","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.yfrne.2004.08.001","article-title":"Human pineal physiology and functional significance of melatonin","volume":"25","author":"Macchi","year":"2004","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.jocn.2017.01.022_b0025","series-title":"Melatonin: a universal photoperiodic signal with diverse actions","first-page":"71","article-title":"Pineal melatonin-immune system interaction1","author":"Poon","year":"1996"},{"key":"10.1016\/j.jocn.2017.01.022_b0030","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1365-2265.1995.tb01869.x","article-title":"Role of melatonin in health and disease","volume":"42","author":"Webb","year":"1995","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.jocn.2017.01.022_b0035","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/S0140-6736(95)92600-3","article-title":"Impaired nocturnal secretion of melatonin in coronary heart disease","volume":"345","author":"Brugger","year":"1995","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jocn.2017.01.022_b0040","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1053\/euhj.1999.1527","article-title":"Decreased melatonin synthesis in patients with coronary artery disease","volume":"20","author":"Sakotnik","year":"1999","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jocn.2017.01.022_b0045","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0002-9149(99)00112-5","article-title":"Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men","volume":"83","author":"Arangino","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jocn.2017.01.022_b0050","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12348","article-title":"Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review","author":"Simko","year":"2016","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0055","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/jpi.12257","article-title":"Inter-relationships of the chronobiotic, melatonin, with leptin and adiponectin: implications for obesity","volume":"59","author":"Szewczyk-Golec","year":"2015","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0060","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3109\/07853890.2011.586365","article-title":"Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression","volume":"44","author":"Reiter","year":"2012","journal-title":"Ann Med"},{"key":"10.1016\/j.jocn.2017.01.022_b0065","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/jpi.12252","article-title":"Melatonin improves bone mineral density at the femoral neck in postmenopausal women with osteopenia: a randomized controlled trial","volume":"59","author":"Amstrup","year":"2015","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0070","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1365-2265.1982.tb01577.x","article-title":"Reduced nocturnal melatonin secretion in chronic schizophrenia: relationship to body weight","volume":"17","author":"Ferrier","year":"1982","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.jocn.2017.01.022_b0075","series-title":"Melatonin: a universal photoperiodic signal with diverse actions","first-page":"174","article-title":"Pineal function in psychiatric disorders","author":"Brown","year":"1996"},{"key":"10.1016\/j.jocn.2017.01.022_b0080","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2165\/00023210-199503030-00006","article-title":"Melatonin in psychiatric and sleep disorders","volume":"3","author":"Brown","year":"1995","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jocn.2017.01.022_b0085","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1177\/074873049701200616","article-title":"Efficacy of melatonin treatment in jet lag, shift work, and blindness","volume":"12","author":"Arendt","year":"1997","journal-title":"J Biol Rhythms"},{"key":"10.1016\/j.jocn.2017.01.022_b0090","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/255344a0","article-title":"Melatonin may be synthesised in enterochromaffin cells","volume":"255","author":"Raikhlin","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.jocn.2017.01.022_b0095","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1007\/s00018-014-1579-2","article-title":"Extrapineal melatonin: sources, regulation, and potential functions","volume":"71","author":"Acu\u00f1a-Castroviejo","year":"2014","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jocn.2017.01.022_b0100","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.3174\/ajnr.A3525","article-title":"Incidental findings in youths volunteering for brain MRI research","volume":"34","author":"Gur","year":"2013","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.jocn.2017.01.022_b0105","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.3171\/2011.6.JNS11506","article-title":"Prevalence and natural history of pineal cysts in adults","volume":"115","author":"Al-Holou","year":"2011","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2017.01.022_b0110","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1227\/00006123-199507000-00002","article-title":"Magnetic resonance images reveal a high incidence of asymptomatic pineal cysts in young women","volume":"37","author":"Sawamura","year":"1995","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jocn.2017.01.022_b0115","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00701-016-2726-3","article-title":"Clinical management of pineal cysts: a worldwide online survey","volume":"158","author":"M\u00e1jovsk\u00fd","year":"2016","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.jocn.2017.01.022_b0120","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0125","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"key":"10.1016\/j.jocn.2017.01.022_b0130","unstructured":"Beck AT, Steer RA, Ball R, Ranieri WF. Comparison of beck depression inventories-IA and-II in psychiatric outpatients. <http:\/\/dx.doi.org\/101207\/s15327752jpa6703_13>; 2010."},{"key":"10.1016\/j.jocn.2017.01.022_b0135","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3959(00)00305-5","article-title":"Validity of the migraine disability assessment (MIDAS) score in comparison to a diary-based measure in a population sample of migraine sufferers","volume":"88","author":"Stewart","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.jocn.2017.01.022_b0140","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1600-079X.1986.tb00760.x","article-title":"Human melatonin production decreases with age","volume":"3","author":"Sack","year":"1986","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0145","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1210\/jcem-66-3-648","article-title":"Alterations in nocturnal serum melatonin levels in humans with growth and aging","volume":"66","author":"Waldhauser","year":"1988","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocn.2017.01.022_b0150","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0006-3223(89)90178-9","article-title":"Circadian rhythms of melatonin and cortisol in aging","volume":"25","author":"Sharma","year":"1989","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jocn.2017.01.022_b0155","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s00381-003-0813-2","article-title":"Pineal cysts in childhood","volume":"19","author":"Mandera","year":"2003","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.jocn.2017.01.022_b0160","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jocn.2011.05.022","article-title":"Nocturnal headache associated with melatonin deficiency due to a pineal gland cyst","volume":"19","author":"Karada\u015f","year":"2012","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.jocn.2017.01.022_b0165","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s11060-008-9792-1","article-title":"Contribution of the daily melatonin profile to diagnosis of tumors of the pineal region","volume":"93","author":"Leston","year":"2009","journal-title":"J Neurooncol"},{"key":"10.1016\/j.jocn.2017.01.022_b0170","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/0748730415616678","article-title":"Prospective study on salivary evening melatonin and sleep before and after pinealectomy in humans","volume":"31","author":"Slawik","year":"2016","journal-title":"J Biol Rhythms"},{"key":"10.1016\/j.jocn.2017.01.022_b0175","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/978-1-62703-616-0_11","article-title":"Measurement of melatonin and 6-sulphatoxymelatonin","volume":"1065","author":"Middleton","year":"2013","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jocn.2017.01.022_b0180","doi-asserted-by":"crossref","first-page":"66","DOI":"10.5664\/jcsm.27083","article-title":"Measuring melatonin in humans","volume":"4","author":"Benloucif","year":"2008","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.jocn.2017.01.022_b0185","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1016\/j.lfs.2003.05.007","article-title":"Reproducibility of the circadian rhythms of serum cortisol and melatonin in healthy subjects: a study of three different 24-h cycles over six weeks","volume":"73","author":"Selmaoui","year":"2003","journal-title":"Life Sci"},{"key":"10.1016\/j.jocn.2017.01.022_b0190","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s40261-015-0368-5","article-title":"The safety of melatonin in humans","volume":"36","author":"Andersen","year":"2016","journal-title":"Clin Drug Investig"},{"key":"10.1016\/j.jocn.2017.01.022_b0195","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/088307380101600215","article-title":"Melatonin replacement therapy in a child with a pineal tumor","volume":"16","author":"Jan","year":"2001","journal-title":"J Child Neurol"},{"key":"10.1016\/j.jocn.2017.01.022_b0200","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1212\/WNL.46.1.261","article-title":"Melatonin replacement corrects sleep disturbances in a child with pineal tumor","volume":"46","author":"Etzioni","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.jocn.2017.01.022_b0205","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1007\/s00701-012-1409-y","article-title":"Sleep disturbance after pinealectomy in patients with pineocytoma WHO\u00b0I","volume":"154","author":"Krieg","year":"2012","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.jocn.2017.01.022_b0210","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1399-6576.2004.00520.x","article-title":"Postoperative elevated cortisol excretion is not associated with suppression of 6-sulfatoxymelatonin excretion","volume":"49","author":"Derenzo","year":"2005","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.jocn.2017.01.022_b0215","first-page":"2438","article-title":"Leptin and the perioperative neuroendocrinological stress response","volume":"84","author":"Kain","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocn.2017.01.022_b0220","first-page":"246","article-title":"Dissociation between plasma adrenocorticotropin and serum cortisol level during the early postoperative period after gastrectomy","volume":"53","author":"Cho","year":"2000","journal-title":"Horm Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0225","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0952-8180(97)00006-8","article-title":"Elevated plasma levels of interleukin-6, interleukin-8, and granulocyte colony-stimulating factor during and after major abdominal surgery","volume":"9","author":"Kato","year":"1997","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jocn.2017.01.022_b0230","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/00000542-199209000-00004","article-title":"Responses of plasma adrenocorticotropic hormone, cortisol, and cytokines during and after upper abdominal surgery","volume":"77","author":"Naito","year":"1992","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jocn.2017.01.022_b0235","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1600-079X.1984.tb00209.x","article-title":"Effects of pinealectomy and aging on the serum corticosterone circadian rhythm in rats","volume":"1","author":"Oxenkrug","year":"1984","journal-title":"J Pineal Res"},{"issue":"10","key":"10.1016\/j.jocn.2017.01.022_b0240","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0024-3205(71)90130-5","article-title":"The effect of pinealectomy on rat plasma corticosterone levels under various conditions of light","volume":"I","author":"Nir","year":"1971","journal-title":"Life Sci"},{"key":"10.1016\/j.jocn.2017.01.022_b0245","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1210\/jc.2002-021048","article-title":"Mt1 Melatonin receptor in the primate adrenal gland: inhibition of adrenocorticotropin-stimulated cortisol production by melatonin","volume":"88","author":"Torres-Farfan","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jocn.2017.01.022_b0250","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1055\/s-0031-1271693","article-title":"Melatonin exerts direct inhibitory actions on ACTH responses in the human adrenal gland","volume":"43","author":"Campino","year":"2011","journal-title":"Horm Metab Res = Horm und Stoffwechselforsch = Horm m\u00e9tabolisme"},{"key":"10.1016\/j.jocn.2017.01.022_b0255","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1600-079X.2007.00460.x","article-title":"Impact of sleep and circadian disturbances in urinary 6-sulphatoxymelatonin levels, on cognitive function after major surgery","volume":"43","author":"G\u00f6genur","year":"2007","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jocn.2017.01.022_b0260","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s00268-006-0256-5","article-title":"Disturbances in melatonin, cortisol and core body temperature rhythms after major surgery","volume":"31","author":"G\u00f6genur","year":"2007","journal-title":"World J Surg"},{"key":"10.1016\/j.jocn.2017.01.022_b0265","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1600-079X.1998.tb00542.x","article-title":"Circadian secretion patterns of melatonin after major surgery","volume":"25","author":"Nishimura","year":"1998","journal-title":"J Pineal Res"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586816311158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586816311158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T07:36:20Z","timestamp":1749972980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586816311158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":53,"alternative-id":["S0967586816311158"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2017.01.022","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melatonin and cortisol secretion profile in patients with pineal cyst before and after pineal cyst resection","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2017.01.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}