{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:54:50Z","timestamp":1777694090942,"version":"3.51.4"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","jocn-journal.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.jocn.2018.08.012","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T16:45:25Z","timestamp":1534956325000},"page":"28-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["The value of serum procalcitonin in acute meningitis in children"],"prefix":"10.1016","volume":"56","author":[{"given":"Hatem H.","family":"El shorbagy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naglaa Fathy","family":"Barseem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleed E.","family":"Abdelghani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hany A.","family":"Suliman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraf H.","family":"Al-shokary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akram E.","family":"Elsadek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehia H. Abdel","family":"Maksoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jehan H.","family":"Sabri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2018.08.012_b0005","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/09629350400003084","article-title":"Serum procalcitonin and cerebrospinal fluid cytokines level in children with meningitis","volume":"13","author":"Taskin","year":"2004","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.jocn.2018.08.012_b0010","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/archpedi.162.12.1157","article-title":"Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case-cohort study","volume":"162","author":"Dubos","year":"2008","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"Pt 2","key":"10.1016\/j.jocn.2018.08.012_b0015","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/000456329703400206","article-title":"Interleukin 6 in cerebrospinal fluid of patients with meningitis is not a useful diagnostic marker in the differential diagnosis of meningitis","volume":"34","author":"Lopez-Cortes","year":"1997","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.jocn.2018.08.012_b0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000336629","article-title":"An update on the use of C-reactive protein in early-onset neonatal sepsis: current insights and new tasks","volume":"102","author":"Hofer","year":"2012","journal-title":"Neonatology"},{"key":"10.1016\/j.jocn.2018.08.012_b0025","series-title":"Infections of the Central Nervous System","first-page":"7","article-title":"Pathogenesis and pathophysiology of viral infections of the Central Nervous System","author":"Cassady","year":"1997"},{"key":"10.1016\/j.jocn.2018.08.012_b0030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0022-2143(99)90053-7","article-title":"Procalcitonin expression in human peripheral blood mononuclear cells and its modulation by lipopolysaccharides and sepsis-related cytokines in vitro","volume":"134","author":"Oberhoffer","year":"1999","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.jocn.2018.08.012_b0035","first-page":"451","article-title":"Procalcitonin in bacterial infections-hype, hope, more or less?","volume":"135","author":"Cbrist-Crain","year":"2005","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.jocn.2018.08.012_b0040","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0022-3476(98)70018-6","article-title":"Neutrophil CD11b expression as a diagnostic marker for early-onset neonatal infection","volume":"132","author":"Weirich","year":"1998","journal-title":"J Pediatr"},{"key":"10.1016\/j.jocn.2018.08.012_b0045","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/adc.81.5.417","article-title":"Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count","volume":"81","author":"Hatherill","year":"1999","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jocn.2018.08.012_b0050","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1086\/513633","article-title":"Procalcitonin in bacterial and viral meningitis in children","volume":"24","author":"Gendrel","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0055","first-page":"127","article-title":"Acute meningitis, acute phase proteins and procalcitonin","volume":"61","author":"Mary","year":"2003","journal-title":"Ann Biol Clin"},{"key":"10.1016\/j.jocn.2018.08.012_b0060","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1086\/425368","article-title":"Practice guidelines for the management of bacterial meningitis","volume":"39","author":"Tunkel","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0065","series-title":"Biochemistry and Clinical Diagnosis","first-page":"3","author":"Procalcitonin","year":"2010"},{"key":"10.1016\/j.jocn.2018.08.012_b0070","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1097\/01.CCM.0000117317.18092.E4","article-title":"Surviving sepsis campaign guidelines for management of severe sepsis and septic shock","volume":"32","author":"Dellinger","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jocn.2018.08.012_b0075","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/cc3722","article-title":"Decrease in serum procalcitonin levels over time during treatment of acute bacterial meningitis","volume":"9","author":"Viallon","year":"2005","journal-title":"Crit Care"},{"key":"10.1016\/j.jocn.2018.08.012_b0080","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jmau.2013.06.007","article-title":"Study of different diagnostic markers used to differentiate septic from aseptic meningitis","volume":"1","author":"Mayah","year":"2013","journal-title":"J Microsc Ultrastruct"},{"key":"10.1016\/j.jocn.2018.08.012_b0085","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1086\/513633","article-title":"Measurement of procalcitonin levels in children with bacterial or viral meningitis","volume":"24","author":"Gendrel","year":"1997","journal-title":"Clin Infect Dis"},{"issue":"9375","key":"10.1016\/j.jocn.2018.08.012_b0090","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1016\/S0140-6736(03)13693-8","article-title":"Bacterial meningitis in children","volume":"361","author":"Saez-Llorens","year":"2003","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.jocn.2018.08.012_b0095","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1086\/425368","article-title":"Practice guidelines for the management of bacterial meningitis","volume":"39","author":"Tunkel","year":"2004","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.jocn.2018.08.012_b0100","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1046\/j.1442-200x.2000.01285.x","article-title":"Serum C-reactive protein in the differential diagnosis of childhood meningitis","volume":"42","author":"Tatara","year":"2000","journal-title":"Pediatr Int"},{"issue":"1","key":"10.1016\/j.jocn.2018.08.012_b0105","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00006454-200001000-00013","article-title":"Value of cerebrospinal fluid leukocyte aggregation in distinguishing the causes of meningitis in children","volume":"19","author":"Michelow","year":"2000","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jocn.2018.08.012_b0110","first-page":"17","article-title":"Serum procalcitonin levels in children with bacterial or viral meningitis","volume":"8","author":"Liu","year":"2006","journal-title":"Zongguo Dang Dai Er Ke Za"},{"issue":"2","key":"10.1016\/j.jocn.2018.08.012_b0115","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/08035250410025140","article-title":"Is procalcitonin useful in early diagnosis of serious bacterial infections in children?","volume":"94","author":"Thayyil","year":"2005","journal-title":"Acta Pediatr"},{"issue":"1","key":"10.1016\/j.jocn.2018.08.012_b0120","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4103\/0974-777X.77290","article-title":"Serum procalcitonin in viral and bacterial meningitis","volume":"3","author":"Alkholi","year":"2011","journal-title":"J Glob Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0125","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0022-3476(88)80372-X","article-title":"C-reactive protein in early detection of bacteremic versus viral infections in immunocompetent and compromised children","volume":"113","author":"Peltola","year":"1999","journal-title":"J Pediatr"},{"key":"10.1016\/j.jocn.2018.08.012_b0130","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s10096-003-1066-4","article-title":"Use of quantitative and semiquantitative procalcitonin measurement to identify children with sepsis and meningitis","volume":"23","author":"Prat","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0135","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s12098-012-0933-3","volume":"80","author":"Prasad","year":"2013","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.jocn.2018.08.012_b0140","first-page":"1605","article-title":"Procalcitonin increase after endotoxin injection in normal subjects","volume":"79","author":"Dandona","year":"1994","journal-title":"J Cin Endocrinol Metab"},{"issue":"53","key":"10.1016\/j.jocn.2018.08.012_b0145","first-page":"755","article-title":"Procalcitonin in diagnosis of purulent and aseptic meningitis in children","volume":"9","author":"Korczowski","year":"2000","journal-title":"Pol Merkur Lekarski"},{"issue":"6\u20137","key":"10.1016\/j.jocn.2018.08.012_b0150","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1080\/00365540601113685","article-title":"Diagnostic value of soluble CD163 serum levels in patients suspected of meningitis: comparison with CRP and procalcitonin","volume":"39","author":"Knudsen","year":"2007","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0155","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s10096-006-0179-y","article-title":"Elevated procalcitonin as a diagnostic marker in meningococcal disease","volume":"25","author":"Mills","year":"2006","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jocn.2018.08.012_b0160","first-page":"114","article-title":"The potential role of procalcitonin in the emergency department management of febrile young adults during a sustained meningococcal epidemic","volume":"16","author":"Bugden","year":"2004","journal-title":"Emerg Med Australas"},{"key":"10.1016\/j.jocn.2018.08.012_b0165","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1097\/00006454-199910000-00008","article-title":"Comparison of procalcitonin with CRP, lnterleukin-6, and interferon-alpha for distinguishing of bacterial vs. viral meningitis","volume":"18","author":"Gendrel","year":"1999","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jocn.2018.08.012_b0170","series-title":"The prognostic value of CSF procalcitonin in acute bacterial meningitis in children","author":"Lupu","year":"2005"},{"issue":"4","key":"10.1016\/j.jocn.2018.08.012_b0175","first-page":"346","article-title":"Diagnostic value of serum procalcitonin levels in children with meningitis: a comparison with blood leukocyte count and C-reactive protein","volume":"61","author":"Ibrahim","year":"2011","journal-title":"J Pak Med Assoc"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586817321082?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586817321082?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T19:38:11Z","timestamp":1539027491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586817321082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":35,"alternative-id":["S0967586817321082"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2018.08.012","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The value of serum procalcitonin in acute meningitis in children","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2018.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}