{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:57:52Z","timestamp":1786993072503,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jocn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.jocn.2018.08.052","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T21:17:50Z","timestamp":1535577470000},"page":"20-25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Increased brain glucose metabolism in chronic severe traumatic brain injury as determined by longitudinal 18F-FDG PET\/CT"],"prefix":"10.1016","volume":"57","author":[{"given":"Tomohiro","family":"Yamaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"Uchino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruko","family":"Henmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuho","family":"Kamezawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyoko","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Ozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Onodera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-6469","authenticated-orcid":false,"given":"Nobuo","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Odaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Itou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2018.08.052_b0005","first-page":"741","article-title":"Disorders of consciousness after severe traumatic brain injury: a Swedish-Icelandic study of incidence, outcomes and implications for optimizing care pathways","volume":"45","author":"Godbolt","year":"2013","journal-title":"J Rehabil"},{"key":"10.1016\/j.jocn.2018.08.052_b0010","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.conb.2012.12.003","article-title":"Consciousness supporting networks","volume":"23","author":"Demertzi","year":"2013","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.jocn.2018.08.052_b0015","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0079-6123(05)50033-5","article-title":"Modeling the minimally conscious state: measurements of brain function and therapeutic possibilities","volume":"150","author":"Schiff","year":"2005","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.jocn.2018.08.052_b0020","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1080\/02699052.2017.1283537","article-title":"Longitudinal changes in brain morphology from 4 weeks to 12 months after mild traumatic brain injury: associations with cognitive functions and clinical variables","volume":"31","author":"Hellstr\u00f8m","year":"2017","journal-title":"Brain Inj"},{"key":"10.1016\/j.jocn.2018.08.052_b0025","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1089\/neu.2016.4418","article-title":"Longitudinal assessment of clinical signs of recovery in patients with unresponsive wakefulness syndrome after traumatic or nontraumatic brain injury","volume":"34","author":"Bagnato","year":"2017","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.jocn.2018.08.052_b0030","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2014.91","article-title":"Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury","volume":"4","author":"Mitsis","year":"2014","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.jocn.2018.08.052_b0035","first-page":"58","article-title":"The clinical relevance of FDG-PET imaging in severe traumatic brain injuries","volume":"49","author":"de la Cueva-Barrao","year":"2009","journal-title":"Rev Neurol"},{"key":"10.1016\/j.jocn.2018.08.052_b0040","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.2967\/jnumed.110.078626","article-title":"Progressive metabolic and structural cerebral perturbations after traumatic brain injury: an in vivo imaging study in the rat","volume":"51","author":"Liu","year":"2010","journal-title":"J Nucl Med."},{"key":"10.1016\/j.jocn.2018.08.052_b0045","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1136\/jnnp-2015-310958","article-title":"Preserved consciousness in vegetative and minimal conscious states: systematic review and meta-analysis","volume":"87","author":"Kondziella","year":"2016","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jocn.2018.08.052_b0050","first-page":"17","article-title":"Assessment of functional improvement in vegetative or minimally conscious patients caused by automotive accidents using a newly designed scoring system","volume":"7","author":"Oka","year":"2007","journal-title":"J Jpn Counc Traffic Sci"},{"key":"10.1016\/j.jocn.2018.08.052_b0055","doi-asserted-by":"crossref","first-page":"921","DOI":"10.3109\/02699052.2012.661911","article-title":"Early motor predictors of recovery in patients with severe traumatic brain injury","volume":"26","author":"Tamashiro","year":"2012","journal-title":"Brain Inj"},{"key":"10.1016\/j.jocn.2018.08.052_b0060","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1097\/00001199-200609000-00003","article-title":"Multimodal neuroimaging approaches to disorders of consciousness","volume":"21","author":"Schiff","year":"2006","journal-title":"J Head Trauma Rehabil"},{"key":"10.1016\/j.jocn.2018.08.052_b0065","doi-asserted-by":"crossref","DOI":"10.1002\/ana.25214","article-title":"Regional brain volumetry and brain function in severely brain-injured patients","author":"Annen","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jocn.2018.08.052_b0070","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1002\/hbm.23269","article-title":"Function-structure connectivity in patients with severe brain injury as measured by MRI-DWI and FDG-PET","volume":"37","author":"Annen","year":"2016","journal-title":"Hum Brain Mapp"},{"issue":"Suppl 2","key":"10.1016\/j.jocn.2018.08.052_b0075","first-page":"158","article-title":"Evaluation of functional improvements of the patients with severe brain injury in the chronic stage using FDG-PET \u2013 Relation between brain FDG uptake and discontinuing of antiepileptics","volume":"54","author":"Uchino","year":"2013","journal-title":"J Nucl Med."},{"key":"10.1016\/j.jocn.2018.08.052_b0080","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.nicl.2017.02.002","article-title":"Measures of metabolism and complexity in the brain of patients with disorders of consciousness","volume":"14","author":"Bodart","year":"2017","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.jocn.2018.08.052_b0085","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1089\/neu.2011.1851","article-title":"A voxel-based analysis of FDG-PET in traumatic brain injury: regional metabolism and relationship between the thalamus and cortical areas","volume":"28","author":"Garc\u00eda-Panach","year":"2011","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.jocn.2018.08.052_b0090","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1159\/000028730","article-title":"Frontal and occipital horn ratio: a linear estimate of ventricular size for multiple imaging modalities in pediatric hydrocephalus","volume":"29","author":"O'Hayon","year":"1998","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.jocn.2018.08.052_b0095","article-title":"Pharmacotherapy for chronic cognitive impairment in traumatic brain injury","volume":"12","author":"Dougall","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jocn.2018.08.052_b0100","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/NRL.0000000000000001","article-title":"Amantadine for patients with severe traumatic brain injury: a critically appraised topic","volume":"19","author":"Spritzer","year":"2015","journal-title":"Neurologist"},{"key":"10.1016\/j.jocn.2018.08.052_b0105","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1056\/NEJMoa1102609","article-title":"Placebo-controlled trial of amantadine for severe traumatic brain injury","volume":"366","author":"Giacino","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jocn.2018.08.052_b0110","article-title":"Antiepileptic drugs as prophylaxis for post-craniotomy seizures","volume":"3","author":"Weston","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jocn.2018.08.052_b0115","first-page":"44","article-title":"Analysis of meaningfully improved patients in chronic stage with severe brain damage after automotive accident: focused on dose of anticonvulsant and pressure setting of shunt device","volume":"9","author":"Oka","year":"2009","journal-title":"J Jpn Counc Traffic Sci"},{"key":"10.1016\/j.jocn.2018.08.052_b0120","first-page":"1308","article-title":"The dose uptake ratio as an index of glucose metabolism: useful parameter or oversimplification?","volume":"35","author":"Hamberg","year":"1994","journal-title":"J Nucl Med"},{"key":"10.1016\/j.jocn.2018.08.052_b0125","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fnene.2013.00013","article-title":"FDG-PET imaging in mild traumatic brain injury: a critical review","volume":"5","author":"Byrnes","year":"2014","journal-title":"Front Neuroenergetics"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586818307033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586818307033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T21:16:50Z","timestamp":1760822210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586818307033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":25,"alternative-id":["S0967586818307033"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2018.08.052","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased brain glucose metabolism in chronic severe traumatic brain injury as determined by longitudinal 18F-FDG PET\/CT","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2018.08.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}