{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:40:39Z","timestamp":1760834439703,"version":"build-2065373602"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jocn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jocn.2019.10.004","type":"journal-article","created":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T16:28:31Z","timestamp":1574526511000},"page":"93-96","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Neurochemical supplementation in patients with depressed levels of participation after brain tumor surgery: Rationale and preliminary results"],"prefix":"10.1016","volume":"71","author":[{"given":"Robert G.","family":"Briggs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed A.","family":"Ahsan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew K.","family":"Conner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron E.","family":"Nix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina C.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan G.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Sheets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali H.","family":"Palejwala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kassem","family":"Chendeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"Sughrue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2019.10.004_b0005","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s11060-011-0772-5","article-title":"Early rehabilitation after surgery improves functional outcome in inpatients with brain tumours","volume":"107","author":"Bartolo","year":"2012","journal-title":"J Neurooncol"},{"key":"10.1016\/j.jocn.2019.10.004_b0010","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1097\/PHM.0b013e31820be31f","article-title":"Brain tumor rehabilitation","volume":"90","author":"Vargo","year":"2011","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jocn.2019.10.004_b0015","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/00002060-200105000-00005","article-title":"Incidence of neurologic deficits and rehabilitation of patients with brain tumors","volume":"80","author":"Mukand","year":"2001","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jocn.2019.10.004_b0020","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1097\/01.cco.0000142076.52721.b3","article-title":"The management of brain edema in brain tumors","volume":"16","author":"Kaal","year":"2004","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.jocn.2019.10.004_b0025","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1136\/jnnp.74.7.901","article-title":"Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation","volume":"74","author":"Duffau","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.jocn.2019.10.004_b0030","series-title":"Brain tumors: an encyclopedic approach","first-page":"163","article-title":"Brain edema, increased intracranial pressure, vascular effects, and other epiphenomena of human brain tumors","author":"Thapar","year":"1995"},{"key":"10.1016\/j.jocn.2019.10.004_b0035","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0072-9752(07)01715-0","article-title":"Altered consciousness associated with brain neoplasms","volume":"90","author":"Mut","year":"2008","journal-title":"Handbook Clin Neurol"},{"key":"10.1016\/j.jocn.2019.10.004_b0040","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1080\/16501970306129","article-title":"Cancer rehabilitation","volume":"35","author":"Fialka-Moser","year":"2003","journal-title":"J Rehabil Med"},{"key":"10.1016\/j.jocn.2019.10.004_b0045","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/ana.410130320","article-title":"Incidence and treatment of peripheral venous thrombosis in patients with glioma","volume":"13","author":"Ruff","year":"1983","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jocn.2019.10.004_b0050","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1055\/s-0038-1649592","article-title":"Venous thromboembolism and high grade gliomas","volume":"70","author":"Dhami","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jocn.2019.10.004_b0055","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3171\/2010.6.JNS091974","article-title":"Risk factors for the development of serious medical complications after resection of meningiomas. Clinical article","volume":"114","author":"Sughrue","year":"2011","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2019.10.004_b0060","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1200\/JCO.1998.16.7.2522","article-title":"Methylphenidate therapy improves cognition, mood, and function of brain tumor patients","volume":"16","author":"Meyers","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jocn.2019.10.004_b0065","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1176\/jnp.7.3.347","article-title":"Methylphenidate in the treatment of neurobehavioral slowing associated with cancer and cancer treatment","volume":"7","author":"Weitzner","year":"1995","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.jocn.2019.10.004_b0070","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S0003-9993(96)90291-9","article-title":"Subacute methylphenidate treatment for moderate to moderately severe traumatic brain injury: a preliminary double-blind placebo-controlled study","volume":"77","author":"Plenger","year":"1996","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.jocn.2019.10.004_b0075","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3109\/02699058809150898","article-title":"Stimulant treatment for the neurobehavioural sequelae of traumatic brain injury","volume":"2","author":"Gualtieri","year":"1988","journal-title":"Brain Inj"},{"key":"10.1016\/j.jocn.2019.10.004_b0080","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0140-6736(01)05966-9","article-title":"Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: a prospective, randomised, double-blind study","volume":"358","author":"Scheidtmann","year":"2001","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jocn.2019.10.004_b0085","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1210\/er.2013-1115","article-title":"Craniopharyngioma","volume":"35","author":"Muller","year":"2014","journal-title":"Endocr Rev"},{"key":"10.1016\/j.jocn.2019.10.004_b0090","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3171\/jns.2004.100.3.0369","article-title":"Intraoperative subcortical stimulation mapping for hemispheric perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients","volume":"100","author":"Evren Keles","year":"2004","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jocn.2019.10.004_b0095","first-page":"45","article-title":"Cortical and subcortical motor mapping in rolandic and perirolandic glioma surgery: impact on postoperative morbidity and extent of resection","volume":"51","author":"Carrabba","year":"2007","journal-title":"J Neurosurg Sci"},{"key":"10.1016\/j.jocn.2019.10.004_b0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3233\/BMR-1993-3204","article-title":"Musculoskeletal complications of cancera survey of 50 patients","volume":"3","author":"Brennan","year":"1993","journal-title":"J Back Musculoskeletal Rehabil"},{"key":"10.1016\/j.jocn.2019.10.004_b0105","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1001\/archneur.56.2.153","article-title":"Neurobiological basis of consciousness","volume":"56","author":"Young","year":"1999","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jocn.2019.10.004_b0110","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0010-0277(00)00127-X","article-title":"Consciousness and the brainstem","volume":"79","author":"Parvizi","year":"2001","journal-title":"Cognition"},{"key":"10.1016\/j.jocn.2019.10.004_b0115","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/NEN.0b013e3182588293","article-title":"Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders","volume":"71","author":"Edlow","year":"2012","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.jocn.2019.10.004_b0120","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/00000542-196701000-00010","article-title":"Chemical transmission and cortical arousal","volume":"28","author":"Krnjevic","year":"1967","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jocn.2019.10.004_b0125","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1113\/jphysiol.1986.sp016112","article-title":"Mechanisms of action of acetylcholine in the guinea-pig cerebral cortex in vitro","volume":"375","author":"McCormick","year":"1986","journal-title":"J Physiol"},{"key":"10.1016\/j.jocn.2019.10.004_b0130","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0301-0082(92)90012-4","article-title":"Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity","volume":"39","author":"McCormick","year":"1992","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.jocn.2019.10.004_b0135","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0079-6123(03)45011-5","article-title":"Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex","volume":"145","author":"Jones","year":"2004","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.jocn.2019.10.004_b0140","first-page":"581","article-title":"Release of acetylcholine from intact cerebral cortex","volume":"580","author":"MacIntosh","year":"1953","journal-title":"Abstr XIX Int Physiol Congr"},{"issue":"Suppl 1","key":"10.1016\/j.jocn.2019.10.004_b0145","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/jnc.13750","article-title":"Current and experimental treatments of Parkinson disease: a guide for neuroscientists","volume":"139","author":"Oertel","year":"2016","journal-title":"J Neurochem"},{"key":"10.1016\/j.jocn.2019.10.004_b0150","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1586\/17512433.2014.966812","article-title":"New treatments for the motor symptoms of Parkinson's disease","volume":"7","author":"Vijverman","year":"2014","journal-title":"Exp Rev Clin Pharmacol"},{"key":"10.1016\/j.jocn.2019.10.004_b0155","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1474-4422(13)70293-X","article-title":"Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study","volume":"13","author":"Olanow","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jocn.2019.10.004_b0160","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s40263-015-0242-2","article-title":"Long-term treatment with extended-release carbidopa-levodopa (IPX066) in early and advanced parkinson's disease: a 9-month open-label extension trial","volume":"29","author":"Waters","year":"2015","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jocn.2019.10.004_b0165","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1517\/14740338.2015.1015986","article-title":"Safety of IPX066, an extended release carbidopa-levodopa formulation, for the treatment of Parkinson's disease","volume":"14","author":"Kestenbaum","year":"2015","journal-title":"Expert Opin Drug Safety"},{"key":"10.1016\/j.jocn.2019.10.004_b0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0007082","article-title":"Dopamine in motor cortex is necessary for skill learning and synaptic plasticity","volume":"4","author":"Molina-Luna","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jocn.2019.10.004_b0175","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3389\/fneur.2013.00145","article-title":"Dopaminergic meso-cortical projections to m1: role in motor learning and motor cortex plasticity","volume":"4","author":"Hosp","year":"2013","journal-title":"Front Neurol"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586819302498?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586819302498?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T21:19:39Z","timestamp":1760822379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586819302498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":35,"alternative-id":["S0967586819302498"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2019.10.004","relation":{},"ISSN":["0967-5868"],"issn-type":[{"type":"print","value":"0967-5868"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurochemical supplementation in patients with depressed levels of participation after brain tumor surgery: Rationale and preliminary results","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2019.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}