{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:38:04Z","timestamp":1783035484928,"version":"3.54.6"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jocn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jocn.2021.07.027","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T12:34:55Z","timestamp":1627302895000},"page":"255-259","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Association between modified frailty index and surgical outcomes in intradural skull base surgery"],"prefix":"10.1016","volume":"91","author":[{"given":"Khodayar","family":"Goshtasbi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Abiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon M.","family":"Lehrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Abouzari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrison W.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid R.","family":"Djalilian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank P.K.","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.","family":"Kuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.jocn.2021.07.027_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9113491","article-title":"Frailty is a better predictor than age of mortality and perioperative complications after surgery for degenerative cervical myelopathy: an analysis of 41,369 patients from the NSQIP database 2010\u20132018","volume":"9","author":"Wilson","year":"2020","journal-title":"J Clin Med"},{"issue":"10","key":"10.1016\/j.jocn.2021.07.027_b0010","doi-asserted-by":"crossref","first-page":"e1243","DOI":"10.1097\/MAO.0000000000002831","article-title":"Increasing frailty, not increasing age, results in increased length of stay following vestibular schwannoma surgery","volume":"41","author":"Casazza","year":"2020","journal-title":"Otol Neurotol"},{"issue":"3","key":"10.1016\/j.jocn.2021.07.027_b0015","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.surg.2020.05.027","article-title":"Frailty is a better predictor than age for outcomes in geriatric patients with rectal cancer undergoing proctectomy","volume":"168","author":"Miller","year":"2020","journal-title":"Surgery"},{"issue":"9868","key":"10.1016\/j.jocn.2021.07.027_b0020","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","article-title":"Frailty in elderly people","volume":"381","author":"Clegg","year":"2013","journal-title":"The Lancet"},{"issue":"5","key":"10.1016\/j.jocn.2021.07.027_b0025","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1503\/cmaj.050051","article-title":"A global clinical measure of fitness and frailty in elderly people","volume":"173","author":"Rockwood","year":"2005","journal-title":"CMAJ"},{"issue":"9","key":"10.1016\/j.jocn.2021.07.027_b0030","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.amjmed.2006.10.018","article-title":"Frailty: an emerging geriatric syndrome","volume":"120","author":"Ahmed","year":"2007","journal-title":"Am J Med"},{"issue":"32_suppl","key":"10.1016\/j.jocn.2021.07.027_b0035","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/014107689709032S07","article-title":"Frailty: help or hindrance?","volume":"90","author":"Powell","year":"1997","journal-title":"J R Soc Med"},{"issue":"3","key":"10.1016\/j.jocn.2021.07.027_b0040","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol Series A"},{"key":"10.1016\/j.jocn.2021.07.027_b0045","doi-asserted-by":"crossref","DOI":"10.1100\/tsw.2001.58","article-title":"Accumulation of deficits as a proxy measure of aging","volume":"1","author":"Mitnitski","year":"2001","journal-title":"Sci World J"},{"issue":"1","key":"10.1016\/j.jocn.2021.07.027_b0050","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jss.2013.01.021","article-title":"Accumulating deficits model of frailty and postoperative mortality and morbidity: its application to a national database","volume":"183","author":"Velanovich","year":"2013","journal-title":"J Surg Res"},{"key":"10.1016\/j.jocn.2021.07.027_b0055","doi-asserted-by":"crossref","unstructured":"Subramaniam S, Aalberg JJ, Soriano RP, Divino CM. New 5-factor modified frailty index using American College of Surgeons NSQIP data. J Am Coll Surg. 2018;226(2):173-81.e8.","DOI":"10.1016\/j.jamcollsurg.2017.11.005"},{"key":"10.1016\/j.jocn.2021.07.027_b0060","article-title":"Utility of the 5-item modified Frailty Index for predicting adverse outcomes following elective anterior cervical discectomy and fusion","author":"Zreik","year":"2020","journal-title":"World Neurosurg"},{"key":"10.1016\/j.jocn.2021.07.027_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.wneu.2018.12.168","article-title":"The modified 5-item frailty index: A concise and useful tool for assessing the impact of frailty on postoperative morbidity following elective posterior lumbar fusions","author":"Weaver","year":"2019","journal-title":"World Neurosurg"},{"issue":"6","key":"10.1016\/j.jocn.2021.07.027_b0070","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1007\/s00268-020-05422-4","article-title":"Frailty is more predictive than age for complications after thyroidectomy for multinodular goiter","volume":"44","author":"Finnerty","year":"2020","journal-title":"World J Surg"},{"issue":"1","key":"10.1016\/j.jocn.2021.07.027_b0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40463-020-00450-5","article-title":"Impact of frailty on inpatient outcomes in thyroid cancer surgery: 10-year results from the US national inpatient sample","volume":"49","author":"Xu","year":"2020","journal-title":"J Otolaryngol-Head Neck Surg"},{"key":"10.1016\/j.jocn.2021.07.027_b0080","doi-asserted-by":"crossref","unstructured":"Keller DS, Reif de Paula T, Kiran RP, Nemeth SK. Evaluating the association of the new National Surgical Quality Improvement Program modified 5-factor frailty index with outcomes in elective colorectal surgery. Colorectal Dis. 2020;22(10):1396-405.","DOI":"10.1111\/codi.15066"},{"key":"10.1016\/j.jocn.2021.07.027_b0085","first-page":"1","article-title":"Frailty predicts morbidity and mortality after laparoscopic cholecystectomy for acute cholecystitis: an ACS-NSQIP cohort analysis","author":"Fagenson","year":"2020","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"10.1016\/j.jocn.2021.07.027_b0090","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jamcollsurg.2009.09.031","article-title":"Toward robust information: data quality and inter-rater reliability in the American College of Surgeons National Surgical Quality Improvement Program","volume":"210","author":"Shiloach","year":"2010","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jocn.2021.07.027_b0095","doi-asserted-by":"crossref","unstructured":"Wardlow RD, Bernstein IA, Orlov CP, Rowan NR. Implications of obesity on endoscopic sinus surgery postoperative complications: an analysis of the NSQIP database. Otolaryngol\u2013Head Neck Surg. 2020:0194599820955180.","DOI":"10.1177\/0194599820955180"},{"issue":"8","key":"10.1016\/j.jocn.2021.07.027_b0100","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1002\/lary.28373","article-title":"Risk assessment of hypertension in carotid body surgeries: A NSQIP analysis","volume":"130","author":"Siddiqui","year":"2020","journal-title":"The Laryngoscope"},{"key":"10.1016\/j.jocn.2021.07.027_b0105","doi-asserted-by":"crossref","unstructured":"Goshtasbi K, Verma SP. Early adverse events following transcervical hypopharyngeal diverticulum surgery. Ann Otol Rhinol Laryngol. 2020:3489420962136.","DOI":"10.1177\/0003489420962136"},{"issue":"5","key":"10.1016\/j.jocn.2021.07.027_b0110","doi-asserted-by":"crossref","first-page":"E340","DOI":"10.1002\/lary.28222","article-title":"Frailty as a predictor of outcomes in patients undergoing head and neck cancer surgery","volume":"130","author":"Goldstein","year":"2020","journal-title":"The Laryngoscope"},{"issue":"8","key":"10.1016\/j.jocn.2021.07.027_b0115","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1001\/jamaoto.2013.3969","article-title":"Frailty as a predictor of morbidity and mortality in inpatient head and neck surgery","volume":"139","author":"Adams","year":"2013","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"26","key":"10.1016\/j.jocn.2021.07.027_b0120","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1056\/NEJMp1011024","article-title":"What is value in health care?","volume":"363","author":"Porter","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jocn.2021.07.027_b0125","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/1741-7015-11-65","article-title":"A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial","volume":"11","author":"Cameron","year":"2013","journal-title":"BMC Med"},{"issue":"3","key":"10.1016\/j.jocn.2021.07.027_b0130","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1053\/apmr.2003.50020","article-title":"A prehabilitation program for physically frail community-living older persons","volume":"84","author":"Gill","year":"2003","journal-title":"Arch Phys Med Rehabil"},{"issue":"6","key":"10.1016\/j.jocn.2021.07.027_b0135","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/hed.20166","article-title":"Complications of craniofacial resection for malignant tumors of the skull base: report of an International Collaborative Study","volume":"27","author":"Ganly","year":"2005","journal-title":"Head Neck"},{"issue":"3","key":"10.1016\/j.jocn.2021.07.027_b0140","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/cncr.25390","article-title":"Craniofacial resection for malignant tumors involving the skull base in the elderly: an international collaborative study","volume":"117","author":"Ganly","year":"2011","journal-title":"Cancer"},{"issue":"6","key":"10.1016\/j.jocn.2021.07.027_b0145","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1002\/lary.27494","article-title":"Predictors of short-term morbidity and mortality in open anterior skull base surgery","volume":"129","author":"Kuan","year":"2019","journal-title":"The Laryngoscope"},{"issue":"1","key":"10.1016\/j.jocn.2021.07.027_b0150","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/0194599814528451","article-title":"Predictors for perioperative outcomes following total laryngectomy: A university HealthSystem Consortium discharge database study","volume":"151","author":"Rutledge","year":"2014","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"11","key":"10.1016\/j.jocn.2021.07.027_b0155","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/hed.1143","article-title":"The American Society of Anesthesiologists' class as a comorbidity index in a cohort of head and neck cancer surgical patients","volume":"23","author":"Reid","year":"2001","journal-title":"Head Neck"},{"issue":"7","key":"10.1016\/j.jocn.2021.07.027_b0160","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1001\/jamaoto.2016.0707","article-title":"Assessment of the predictive value of the modified frailty index for Clavien-Dindo Grade IV critical care complications in major head and neck cancer operations","volume":"142","author":"Abt","year":"2016","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"2","key":"10.1016\/j.jocn.2021.07.027_b0165","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.critrevonc.2009.09.007","article-title":"Prescribers' attitudes toward elderly breast cancer patients. Discrimination or empathy?","volume":"75","author":"Proti\u00e8re","year":"2010","journal-title":"Crit Rev Oncol\/Hematol"},{"issue":"1","key":"10.1016\/j.jocn.2021.07.027_b0170","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ijrobp.2014.03.050","article-title":"Age disparity in palliative radiation therapy among patients with advanced cancer","volume":"90","author":"Wong","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.jocn.2021.07.027_b0175","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1001\/archotol.127.2.127","article-title":"Benchmarks for mortality, morbidity, and length of stay for head and neck surgical procedures","volume":"127","author":"Bhattacharyya","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"2 Pt 1","key":"10.1016\/j.jocn.2021.07.027_b0180","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00005537-200002010-00005","article-title":"Length of stay after free flap reconstruction of the head and neck","volume":"110","author":"Ryan","year":"2000","journal-title":"The Laryngoscope"},{"issue":"2","key":"10.1016\/j.jocn.2021.07.027_b0185","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1001\/jamasurg.2017.4007","article-title":"Association of patient frailty with increased morbidity after common ambulatory general surgery operations","volume":"153","author":"Seib","year":"2018","journal-title":"JAMA Surg"},{"issue":"7","key":"10.1016\/j.jocn.2021.07.027_b0190","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1001\/jama.291.7.844","article-title":"Predictors of new-onset kidney disease in a community-based population","volume":"291","author":"Fox","year":"2004","journal-title":"JAMA"},{"issue":"10","key":"10.1016\/j.jocn.2021.07.027_b0195","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/ggi.12910","article-title":"Relationship between chronic kidney disease with diabetes or hypertension and frailty in community-dwelling Japanese older adults","volume":"17","author":"Lee","year":"2017","journal-title":"Geriatr Gerontol Int"},{"issue":"7","key":"10.1016\/j.jocn.2021.07.027_b0200","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.annepidem.2005.10.003","article-title":"The association of race with frailty: the cardiovascular health study","volume":"16","author":"Hirsch","year":"2006","journal-title":"Ann Epidemiol"},{"issue":"6","key":"10.1016\/j.jocn.2021.07.027_b0205","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/j.1532-5415.2005.53300.x","article-title":"The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies","volume":"53","author":"Blaum","year":"2005","journal-title":"J Am Geriatr Soc"},{"issue":"8","key":"10.1016\/j.jocn.2021.07.027_b0210","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1002\/jso.24617","article-title":"Modified frailty index predicts postoperative outcomes in older gastrointestinal cancer patients","volume":"115","author":"Vermillion","year":"2017","journal-title":"J Surg Oncol"},{"issue":"8","key":"10.1016\/j.jocn.2021.07.027_b0215","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/j.1532-5415.2007.01259.x","article-title":"Frailty in older men: prevalence, progression, and relationship with mortality","volume":"55","author":"Cawthon","year":"2007","journal-title":"J Am Geriatr Soc"},{"issue":"20","key":"10.1016\/j.jocn.2021.07.027_b0220","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1001\/jama.2014.4573","article-title":"Preoperative assessment of the older patient: a narrative review","volume":"311","author":"Oresanya","year":"2014","journal-title":"JAMA"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586821003787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586821003787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T21:28:51Z","timestamp":1760822931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586821003787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":44,"alternative-id":["S0967586821003787"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2021.07.027","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between modified frailty index and surgical outcomes in intradural skull base surgery","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2021.07.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}