{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T23:38:24Z","timestamp":1789256304784,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jocn-journal.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.jocn.2024.110979","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T07:51:16Z","timestamp":1734076276000},"page":"110979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The 5-factor modified frailty index as a prognostic factor following stereotactic radiosurgery for metastatic disease to the brain from non-small cell lung cancer: A multi-center cohort analysis"],"prefix":"10.1016","volume":"132","author":[{"given":"Sujay","family":"Rajkumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trent","family":"Kite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Lucido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mathieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjul","family":"Tripathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navneet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Mantziaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stylianos","family":"Pikis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason P.","family":"Sheehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney E.","family":"Wegner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Shepard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2024.110979_b0005","article-title":"Brain metastasis","volume":"20(1):4-","author":"Boire","year":"2020","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"10.1016\/j.jocn.2024.110979_b0010","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1055\/s-0043-1769754","article-title":"Stereotactic radiosurgery as treatment for brain metastases: an update","volume":"18","author":"Pe\u00f1a-Pino","year":"2023","journal-title":"Asian J Neurosurg"},{"issue":"3","key":"10.1016\/j.jocn.2024.110979_b0015","first-page":"90","article-title":"The expanding role of radiosurgery for brain metastases","volume":"5","author":"O\u2019Beirn","year":"2018","journal-title":"Medicines (Basel)"},{"key":"10.1016\/j.jocn.2024.110979_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.wnsx.2023.100170","article-title":"Stereotactic radiosurgery versus whole-brain radiotherapy after resection of solitary brain metastasis: a systematic review and meta-analysis","volume":"18","author":"Vlachos","year":"2023","journal-title":"WORLD Neurosurg X"},{"issue":"11","key":"10.1016\/j.jocn.2024.110979_b0025","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.3390\/jcm9113491","article-title":"Frailty is a better predictor than age of mortality and perioperative complications after surgery for degenerative cervical myelopathy: an analysis of 41,369 patients from the NSQIP database 2010\u20132018","volume":"9","author":"Wilson","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.jocn.2024.110979_b0030","article-title":"Frailty as a predictor of neurosurgical outcomes in brain tumor patients: A systematic review and meta-analysis","volume":"14","author":"Zhu","year":"2023","journal-title":"Front Psychiatry"},{"issue":"4","key":"10.1016\/j.jocn.2024.110979_b0035","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.jamcollsurg.2018.12.036","article-title":"Preoperative frailty and surgical outcomes across diverse surgical subspecialties in a large health care system","volume":"228","author":"Mrdutt","year":"2019","journal-title":"J Am Coll Surg"},{"issue":"1","key":"10.1016\/j.jocn.2024.110979_b0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.14245\/ns.2142770.385","article-title":"Frailty status is a more robust predictor than age of spinal tumor surgery outcomes: a NSQIP analysis of 4,662 patients","volume":"19","author":"Kazim","year":"2022","journal-title":"Neurospine"},{"key":"10.1016\/j.jocn.2024.110979_b0045","doi-asserted-by":"crossref","unstructured":"Kerschbaumer J, Krigers A, Demetz M, Pinggera D, Klingenschmid J, Pichler N, Thom\u00e9 C, Freyschlag CF. The Clinical Frailty Scale as useful tool in patients with brain metastases. J Neurooncol. 2022 May;158(1):51-57. doi: 10.1007\/s11060-022-04008-5. Epub 2022 Apr 13. PMID: 35419752; PMCID: PMC9166853.","DOI":"10.1007\/s11060-022-04008-5"},{"key":"10.1016\/j.jocn.2024.110979_b0050","doi-asserted-by":"crossref","unstructured":"Krigers, N Pichler, J Kerschbaumer, M Demetz, J Klingenschmid, C Thom\u00e9, C F Freyschlag, P08.04.B The Clinical Frailty Scale is superior to the Karnofsky Performance Status as predictor of overall survival in patients with surgical treatment of brain metastases, Neuro-Oncology, Volume 24, Issue Supplement_2, September 2022, Page ii43, https:\/\/doi.org\/10.1093\/neuonc\/noac174.148.","DOI":"10.1093\/neuonc\/noac174.148"},{"issue":"4","key":"10.1016\/j.jocn.2024.110979_b0055","doi-asserted-by":"crossref","first-page":"929","DOI":"10.3171\/2023.7.JNS231214","article-title":"The 5-factor modified frailty index as a prognostic factor of stereotactic radiosurgery for metastatic disease to the brain","volume":"140","author":"Lucido","year":"2024","journal-title":"J Neurosurg"},{"issue":"1","key":"10.1016\/j.jocn.2024.110979_b0060","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3171\/2020.5.JNS20766","article-title":"The 5-factor modified frailty index: an effective predictor of mortality in brain tumor patients","volume":"135","author":"Khalafallah","year":"2020","journal-title":"J Neurosurg"},{"issue":"2","key":"10.1016\/j.jocn.2024.110979_b0065","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jamcollsurg.2017.11.005","article-title":"New 5-factor modified frailty index using American College of Surgeons NSQIP data","volume":"226","author":"Subramaniam","year":"2018","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jocn.2024.110979_b0070","doi-asserted-by":"crossref","first-page":"e626","DOI":"10.1016\/j.wneu.2018.12.168","article-title":"The modified 5-item frailty index: a concise and useful tool for assessing the impact of frailty on postoperative morbidity following elective posterior lumbar fusions","volume":"124","author":"Weaver","year":"2019","journal-title":"WORLD Neurosurg"},{"key":"10.1016\/j.jocn.2024.110979_b0075","article-title":"The 5-factor modified Frailty Index (mFI-5) predicts adverse outcomes after elective Anterior Lumbar Interbody Fusion (ALIF)","volume":"13","author":"Patel","year":"2023","journal-title":"N Am Spine Soc J"},{"key":"10.1016\/j.jocn.2024.110979_b0080","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1186\/s12957-023-03150-2","article-title":"The five-item modified frailty index predicts long-term outcomes in elderly patients undergoing colorectal cancer surgery","volume":"21","author":"Ogata","year":"2023","journal-title":"World J Surg Oncol"},{"issue":"6","key":"10.1016\/j.jocn.2024.110979_b0085","doi-asserted-by":"crossref","first-page":"e270","DOI":"10.1016\/S1470-2045(15)70057-4","article-title":"Response assessment criteria for brain metastases: proposal from the RANO group","volume":"16","author":"Lin","year":"2015","journal-title":"Lancet Oncol"},{"issue":"5","key":"10.1016\/j.jocn.2024.110979_b0090","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.ijrobp.2016.08.039","article-title":"Association between radiation necrosis and tumor biology after stereotactic radiosurgery for brain metastasis","volume":"96","author":"Miller","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10.1016\/j.jocn.2024.110979_b0095","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.ijrobp.2013.05.015","article-title":"Challenges with the diagnosis and treatment of cerebral radiation necrosis","volume":"87","author":"Chao","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.jocn.2024.110979_b0100","first-page":"484","article-title":"Leptomeningeal metastases: a RANO proposal for response criteria","volume":"19","author":"Chamberlain","year":"2017","journal-title":"Neuro Oncol"},{"issue":"5","key":"10.1016\/j.jocn.2024.110979_b0105","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/neuonc\/noz024","article-title":"The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal","volume":"21","author":"Le Rhun","year":"2019","journal-title":"Neuro Oncol"},{"issue":"2","key":"10.1016\/j.jocn.2024.110979_b0110","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.0475","article-title":"Association of brain metastases with survival in patients with limited or stable extracranial disease: a systematic review and meta-analysis","volume":"6","author":"Li","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"4","key":"10.1016\/j.jocn.2024.110979_b0115","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.10117","article-title":"Intracranial and extracranial progression and their correlation with overall survival after stereotactic radiosurgery in a multi-institutional cohort with brain metastases","volume":"6","author":"Carpenter","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"3","key":"10.1016\/j.jocn.2024.110979_b0120","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1269\/jrr.90130","article-title":"Outcome of stereotactic radiosurgery for patients with non-small cell lung cancer metastatic to the brain","volume":"51","author":"Mariya","year":"2010","journal-title":"J Radiat Res"},{"issue":"11","key":"10.1016\/j.jocn.2024.110979_b0125","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1177\/0284185119831692","article-title":"A 3D quantitative imaging biomarker in pre-treatment MRI predicts overall survival after stereotactic radiation therapy of patients with a singular brain metastasis","volume":"60","author":"Della Seta","year":"2019","journal-title":"Acta Radiol"},{"issue":"1072","key":"10.1016\/j.jocn.2024.110979_b0130","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20170022","article-title":"Outcome appraisal of patients with limited brain metastases (BMs) from non small cell lung cancer (NSCLC) treated with different local therapeutic strategies: a single institute evaluation","volume":"90","author":"Pessina","year":"2017","journal-title":"Br J Radiol"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586824005186?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586824005186?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T20:11:19Z","timestamp":1737749479000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586824005186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":26,"alternative-id":["S0967586824005186"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2024.110979","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The 5-factor modified frailty index as a prognostic factor following stereotactic radiosurgery for metastatic disease to the brain from non-small cell lung cancer: A multi-center cohort analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2024.110979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110979"}}