{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T02:14:06Z","timestamp":1788488046232,"version":"build-2803163510"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jocn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jocn.2026.112218","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T06:41:44Z","timestamp":1785220904000},"page":"112218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Prognostic value of the Island sign for hematoma expansion and functional outcome after intracerebral hemorrhage: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"153","author":[{"given":"Maria Clara","family":"Nery Cardoso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davi Chaves Rocha de","family":"Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maianna Sancho","family":"Lago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9o Santana","family":"Campos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Emanuelle","family":"Cunha Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Rios","family":"Beserra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Nunes S\u00e1 Barreto","family":"Magalh\u00e3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Fernanda","family":"Nery Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Conrado","family":"Silva Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jocn.2026.112218_b0005","article-title":"Predictors of hematoma expansion and clinical outcomes in spontaneous intracerebral hemorrhage: imaging markers on non-contrast computed tomography","volume":"238","author":"Parry","year":"2025","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.jocn.2026.112218_b0010","article-title":"Early hematoma expansion and clinical outcomes in patients with spontaneous intracerebral hemorrhage: a multicenter cohort study","volume":"16","author":"Zeng","year":"2025","journal-title":"Front Neurol"},{"key":"10.1016\/j.jocn.2026.112218_b0015","first-page":"3124","article-title":"Non-contrast CT markers for predicting hematoma expansion and prognosis in intracerebral hemorrhage: a systematic evaluation","volume":"34","author":"Song","year":"2024","journal-title":"Eur Radiol"},{"key":"10.1016\/j.jocn.2026.112218_b0020","first-page":"765","article-title":"The island sign as a novel predictor of hematoma expansion in spontaneous intracerebral hemorrhage","volume":"61","author":"Quintas-Neves","year":"2019","journal-title":"Neuroradiology"},{"key":"10.1016\/j.jocn.2026.112218_b0025","first-page":"e70","article-title":"Island sign predicts hematoma expansion and poor outcome after intracerebral hemorrhage","volume":"52","author":"Yang","year":"2021","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2026.112218_b0030","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1161\/STROKEAHA.117.017985","article-title":"Island sign: an imaging predictor for early hematoma expansion and poor outcome in patients with intracerebral hemorrhage","volume":"48","author":"Li","year":"2017","journal-title":"Stroke"},{"issue":"10135","key":"10.1016\/j.jocn.2026.112218_b0035","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1016\/S0140-6736(18)31033-X","article-title":"Tranexamic acid for hyperacute primary intracerebral haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial","volume":"391","author":"Sprigg","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jocn.2026.112218_b0040","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3389\/fneur.2020.00429","article-title":"Island sign predicts hematoma expansion and poor outcome after intracerebral hemorrhage: a systematic review and meta-analysis","volume":"11","author":"Wei","year":"2020","journal-title":"Front Neurol"},{"key":"10.1016\/j.jocn.2026.112218_b0045","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1161\/STROKEAHA.116.015062","article-title":"Noncontrast computed tomography markers of intracerebral hemorrhage expansion","volume":"48","author":"Boulouis","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2026.112218_b0050","first-page":"694","article-title":"Prediction of hematoma growth and outcome in patients with intracerebral hemorrhage using the CT angiography spot sign","volume":"43","author":"Demchuk","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2026.112218_b0055","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1161\/STROKEAHA.115.009185","article-title":"Blend sign on computed tomography: novel and reliable predictor for early hematoma growth in patients with intracerebral hemorrhage","volume":"46","author":"Li","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2026.112218_b0060","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1161\/STROKEAHA.117.020138","article-title":"Predicting intracerebral hemorrhage expansion with noncontrast computed tomography: the BAT score","volume":"49","author":"Morotti","year":"2018","journal-title":"Stroke"},{"key":"10.1016\/j.jocn.2026.112218_b0065","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12883-025-04100-z","article-title":"Early NCCT imaging signs for prognostication in intracerebral hemorrhage: a retrospective cohort study with long follow up results","volume":"25","author":"Deng","year":"2025","journal-title":"BMC Neurol"},{"key":"10.1016\/j.jocn.2026.112218_b0070","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3390\/neurolint17100170","article-title":"Clinical and radiological predictors for early hematoma expansion after spontaneous intracerebral hemorrhage: a retrospective study","volume":"17","author":"Kim","year":"2025","journal-title":"Neurol Int"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586826003693?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586826003693?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T01:47:54Z","timestamp":1788486474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586826003693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":14,"alternative-id":["S0967586826003693"],"URL":"https:\/\/doi.org\/10.1016\/j.jocn.2026.112218","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic value of the Island sign for hematoma expansion and functional outcome after intracerebral hemorrhage: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jocn.2026.112218","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112218"}}