{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:34:22Z","timestamp":1790285662751,"version":"4.1.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T00:00:00Z","timestamp":1571702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the impact of glaucoma-associated vision loss on quality of life and social functioning in Indians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study with prospective enrollment was conducted. Participants were divided as: mild, moderate, and severe. Severity of glaucoma was stratified by the degree of binocular visual field loss in accordance with the Nelson Glaucoma Severity Scale (NGSS). The Glaucoma Quality of Life-15 (GQL-15) and a self-developed social function scale (SFS) were utilized to assess patients' wellbeing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 260 patients (mean \u00b1 SD age = 58.1 \u00b1 12.01 years; 106 females) participated in the study. Univariate analyses revealed a significant relationship between final quality of life score and number of anti-glaucoma medications (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.01), previous surgeries (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00), patients age (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00), patients education level (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02), and severity of glaucoma (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00). Previous surgeries (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04) and severity of glaucoma (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00) were significant predictors of GQL-15 summary score. With increasing glaucoma severity, patients noted greater difficulty with peripheral vision, glare and dark adaptation, and outdoor tasks (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001). Severe glaucoma also impacted patients' functional performance\u2014a significant decline was observed in sense of personal (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001) and social wellbeing (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with advanced glaucoma report significant decline in functioning, their ability to interact in community, take care of self, and do leisure activities. Glaucoma imposes greater social burden on the elderly by impacting their sense of personal safety. Targeted visual and social rehabilitative programs are necessary to improve their wellbeing and independent functioning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.joco.2019.09.006","type":"journal-article","created":{"date-parts":[[2019,11,16]],"date-time":"2019-11-16T13:22:02Z","timestamp":1573910522000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Impact of Visual Impairment on the Wellbeing and Functional Disability of Patients with Glaucoma in India"],"prefix":"10.4103","volume":"32","author":[{"given":"Suneeta","family":"Dubey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harleen","family":"Bedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manveen","family":"Bedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Matah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jigyasa","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saptarshi","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lokesh","family":"Chauhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-2-20240910","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"R2-2-20240910","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.ajo.2011.06.004","article-title":"An assessment of the health and economic burdens of glaucoma","volume":"152","author":"Varma","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"R3-2-20240910","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1001\/archopht.124.12.1754","article-title":"The economic burden of major adult visual disorders in the United States","volume":"124","author":"Rein","year":"2006","journal-title":"Arch Ophthalmol"},{"key":"R4-2-20240910","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ics.2005.05.091","article-title":"Cost-analysis of glaucoma-related blindness in Europe","volume":"1282","author":"Poulsen","year":"2005","journal-title":"Int Congr Ser"},{"key":"R5-2-20240910","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1185\/03007990802111068","article-title":"Late-stage, primary open-angle glaucoma in Europe: Social and health care maintenance costs and quality of life of patients from 4 countries","volume":"24","author":"Thygesen","year":"2008","journal-title":"Curr Med Res Opin"},{"key":"R6-2-20240910","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1159\/000350553","article-title":"Health- and vision-related quality of life in patients with ocular hypertension or primary open-angle glaucoma","volume":"229","author":"Wolfram","year":"2013","journal-title":"Ophthalmologica"},{"key":"R7-2-20240910","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0161-6420(98)94031-3","article-title":"The prevalence of glaucoma in the Melbourne visual impairment project","volume":"105","author":"Wensor","year":"1998","journal-title":"Ophthalmol"},{"key":"R8-2-20240910","first-page":"821","article-title":"The Barbados eye study","volume":"112","author":"Leske","year":"1994","journal-title":"Prevalence of open angle glaucoma. 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