{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:42:29Z","timestamp":1788871349002,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"publisher","award":["20070558205"],"award-info":[{"award-number":["20070558205"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30872876"],"award-info":[{"award-number":["30872876"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["9151008901000199"],"award-info":[{"award-number":["9151008901000199"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1016\/j.joen.2010.08.041","type":"journal-article","created":{"date-parts":[[2010,10,18]],"date-time":"2010-10-18T01:45:27Z","timestamp":1287366327000},"page":"1972-1977","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Expression of Erythropoietin and Erythropoietin Receptor in Human Dental Pulp"],"prefix":"10.1016","volume":"36","author":[{"given":"Qimei","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqi","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2010.08.041_bib1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1601-0825.2006.01346.x","article-title":"Stem cells and the dental pulp: potential roles in dentine regeneration and repair","volume":"13","author":"Sloan","year":"2007","journal-title":"Oral Dis"},{"key":"10.1016\/j.joen.2010.08.041_bib2","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.joen.2009.03.001","article-title":"Hypoxia-amplified proliferation of human dental pulp cells","volume":"35","author":"Sakdee","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2010.08.041_bib3","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1177\/154405910608500909","article-title":"Re-oxygenation improves hypoxia-induced pulp cell arrest","volume":"85","author":"Ueno","year":"2006","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2010.08.041_bib4","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1111\/j.1432-0436.2008.00282.x","article-title":"Effect of ischemic culture conditions on the survival and differentiation of porcine dental pulp-derived cells","volume":"76","author":"Agata","year":"2008","journal-title":"Differentiation"},{"key":"10.1016\/j.joen.2010.08.041_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/08977199909001060","article-title":"Erythropoietin and erythropoietin receptor","volume":"17","author":"Tilbrook","year":"1999","journal-title":"Growth Factors"},{"key":"10.1016\/j.joen.2010.08.041_bib6","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/j.1440-1681.2006.04474.x","article-title":"Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression","volume":"33","author":"Stockmann","year":"2006","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.joen.2010.08.041_bib7","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1016\/j.yexcr.2009.07.016","article-title":"Erythropoietin protects myocardin-expressing cardiac stem cells against cytotoxicity of tumor necrosis factor-alpha","volume":"315","author":"Madonna","year":"2009","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.joen.2010.08.041_bib8","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1634\/theoncologist.9-90005-18","article-title":"The erythropoietin receptor and its expression in tumor cells and other tissues","volume":"9","author":"Farrell","year":"2004","journal-title":"Oncologist"},{"key":"10.1016\/j.joen.2010.08.041_bib9","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1073\/pnas.91.9.3974","article-title":"Erythropoietin receptor mRNA expression in human endothelial cells","volume":"91","author":"Anagnostou","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.joen.2010.08.041_bib10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.brainres.2004.06.057","article-title":"Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain","volume":"1021","author":"Spandou","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.joen.2010.08.041_bib11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1365-2141.2008.07014.x","article-title":"The non-haematopoietic biological effects of erythropoietin","volume":"141","author":"Arcasoy","year":"2008","journal-title":"Br J Haematol"},{"key":"10.1016\/j.joen.2010.08.041_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2119\/molmed.2009.00051","article-title":"Nonerythropoietic tissue protective compounds are highly effective facilitators of wound healing","volume":"15","author":"Erbayraktar","year":"2009","journal-title":"Mol Med"},{"key":"10.1016\/j.joen.2010.08.041_bib13","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1182\/blood.V93.8.2627","article-title":"Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo","volume":"93","author":"Ribatti","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.joen.2010.08.041_bib14","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.cardiores.2006.06.003","article-title":"Reduction of inflammatory cytokine expression and oxidative damage by erythropoietin in chronic heart failure","volume":"71","author":"Li","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.joen.2010.08.041_bib15","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/j.lfs.2005.09.053","article-title":"Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion","volume":"78","author":"Liu","year":"2006","journal-title":"Life Sci"},{"key":"10.1016\/j.joen.2010.08.041_bib16","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s12325-008-0114-y","article-title":"The role of erythropoietin in hemorrhagic shock-induced liver and renal injury in rats","volume":"25","author":"Algin","year":"2008","journal-title":"Adv Ther"},{"key":"10.1016\/j.joen.2010.08.041_bib17","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1365-2591.2007.01215.x","article-title":"Irreversible but not reversible pulpitis is associated with up-regulation of tumour necrosis factor-alpha gene expression in human pulp","volume":"40","author":"Kokkas","year":"2007","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2010.08.041_bib18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S1043-4666(03)00116-9","article-title":"Cytokine gene expression\u2013part of host defensce in pulpitis","volume":"22","author":"Zehnder","year":"2003","journal-title":"Cytokine"},{"key":"10.1016\/j.joen.2010.08.041_bib19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.joen.2009.11.018","article-title":"Side population increase after simulated transient ischemia in human dental pulp cell","volume":"36","author":"Wang","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2010.08.041_bib20","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.exphem.2007.01.044","article-title":"Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells","volume":"35","author":"Zwezdaryk","year":"2007","journal-title":"Exp Hematol"},{"key":"10.1016\/j.joen.2010.08.041_bib21","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.cardiores.2006.07.001","article-title":"Beyond erythropoiesis: the anti-inflammatory effects of erythropoietin","volume":"71","author":"Feng","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.joen.2010.08.041_bib22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000092098","article-title":"Erythropoietin, a cytoprotective and regenerative cytokine, and the hypoxic brain","volume":"3","author":"Pacary","year":"2006","journal-title":"Neurodegener Dis"},{"key":"10.1016\/j.joen.2010.08.041_bib23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/cvr\/cvn090","article-title":"Coupling erythropoietin secretion to mesenchymal stromal cells enhances their regenerative properties","volume":"79","author":"Copland","year":"2008","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.joen.2010.08.041_bib24","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10557-007-6005-7","article-title":"Erythropoietin attenuates the development of experimental autoimmune myocarditis","volume":"21","author":"Hirose","year":"2007","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.joen.2010.08.041_bib25","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jneuroim.2005.10.016","article-title":"Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis","volume":"172","author":"Savino","year":"2006","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.joen.2010.08.041_bib26","first-page":"834","article-title":"Reduction of pulmonary inflammatory response by erythropoietin in a rat model of endotoxaemia","volume":"122","author":"Shang","year":"2009","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.joen.2010.08.041_bib27","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.brainres.2010.03.072","article-title":"Upregulation of erythropoietin in rat peripheral nervous system with experimental autoimmune neuritis","volume":"1333","author":"Ahn","year":"2010","journal-title":"Brain Res"},{"key":"10.1016\/j.joen.2010.08.041_bib28","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.cyto.2008.12.005","article-title":"Erythropoietin augments the cytokine response to acute endotoxin-induced inflammation in humans","volume":"45","author":"Hojman","year":"2009","journal-title":"Cytokine"},{"key":"10.1016\/j.joen.2010.08.041_bib29","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s004010000297","article-title":"Erythropoietin and erythropoietin receptor in human ischemic\/hypoxic brain","volume":"101","author":"Siren","year":"2001","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.joen.2010.08.041_bib30","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1182\/blood-2004-02-0744","article-title":"Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells","volume":"104","author":"Beleslin-Cokic","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.joen.2010.08.041_bib31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1158\/1078-0432.20.11.1","article-title":"Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia","volume":"11","author":"Arcasoy","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.joen.2010.08.041_bib32","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1096\/fj.08-109462","article-title":"Erythropoietin administration after myocardial infarction in mice attenuates ischemic cardiomyopathy associated with enhanced homing of bone marrow-derived progenitor cells via the CXCR-4\/SDF-1 axis","volume":"23","author":"Brunner","year":"2009","journal-title":"FASEB J"},{"key":"10.1016\/j.joen.2010.08.041_bib33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cytogfr.2009.10.012","article-title":"Human dental pulp stem cells with highly angiogenic and neurogenic potential for possible use in pulp regeneration","volume":"20","author":"Nakashima","year":"2009","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.joen.2010.08.041_bib34","doi-asserted-by":"crossref","first-page":"25875","DOI":"10.1074\/jbc.M701988200","article-title":"Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation","volume":"282","author":"Chen","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1016\/j.joen.2010.08.041_bib35","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.bbrc.2005.10.218","article-title":"ERK-mediated production of neurotrophic factors by astrocytes promotes neuronal stem cell differentiation by erythropoietin","volume":"339","author":"Park","year":"2006","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009923991000717X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009923991000717X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:43:40Z","timestamp":1758829420000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009923991000717X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S009923991000717X"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2010.08.041","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of Erythropoietin and Erythropoietin Receptor in Human Dental Pulp","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2010.08.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}