{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:58:47Z","timestamp":1773089927069,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.joen.2012.02.003","type":"journal-article","created":{"date-parts":[[2012,3,5]],"date-time":"2012-03-05T20:54:24Z","timestamp":1330980864000},"page":"753-756","source":"Crossref","is-referenced-by-count":36,"title":["Comparative Evaluation of 1.8 mL and 3.6 mL of 2% Lidocaine with 1:200,000 Epinephrine for Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Prospective, Randomized Single-blind Study"],"prefix":"10.1016","volume":"38","author":[{"given":"Vivek","family":"Aggarwal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamta","family":"Singla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Miglani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarita","family":"Kohli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2012.02.003_bib1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0099-2399(89)80091-3","article-title":"An evaluation of volumes and concentrations of lidocaine in human inferior alveolar nerve block","volume":"15","author":"Vreeland","year":"1989","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.don.0000140576.36513.cb","article-title":"A comparison of articaine and lidocaine for inferior alveolar nerve blocks","volume":"31","author":"Mikesell","year":"2005","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib3","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1600-9657.1999.tb00782.x","article-title":"Failure of inferior alveolar nerve block in endodontics","volume":"15","author":"Poto\u0107nik","year":"1999","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.joen.2012.02.003_bib4","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.joen.2009.04.012","article-title":"Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine following an inferior alveolar nerve block in patients with irreversible pulpitis","volume":"35","author":"Aggarwal","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.tripleo.2009.09.016","article-title":"Comparative evaluation of anesthetic efficacy of Gow-Gates mandibular conduction anesthesia, Vazirani-Akinosi technique, buccal-pluslingual infiltrations, and conventional inferior alveolar nerve anesthesia in patientswith irreversible pulpitis","volume":"109","author":"Aggarwal","year":"2010","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib6","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.joen.2009.11.010","volume":"36","author":"Aggarwal","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.joen.2011.01.016","article-title":"Comparative evaluation of local infiltration of articaine, articaine plus ketorolacand dexamethasone on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis","volume":"37","author":"Aggarwal","year":"2011","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib8","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0007-117X(77)90010-5","article-title":"Some anatomical and physiological causes of failure to achieve mandibular analgesia","volume":"15","author":"Rood","year":"1977","journal-title":"Br J Oral Surg"},{"key":"10.1016\/j.joen.2012.02.003_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1034\/j.1601-1546.2002.10103.x","article-title":"Local anesthetic failure in endodontics: mechanisms and Management","volume":"1","author":"Hargreaves","year":"2002","journal-title":"Endod Topics"},{"key":"10.1016\/j.joen.2012.02.003_bib10","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/01.DON.0000125317.21892.8F","article-title":"Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis","volume":"30","author":"Claffey","year":"2004","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib11","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/0030-4220(82)90209-2","article-title":"The anatomy of mandibular anesthesia: review and analysis","volume":"54","author":"Coleman","year":"1982","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2012.02.003_bib12","series-title":"Local Anesthesia and Pain Control in Dental Practice","author":"Monheim","year":"1961"},{"key":"10.1016\/j.joen.2012.02.003_bib13","series-title":"Handbook of Local Anesthesia","author":"Malamed","year":"1997"},{"key":"10.1016\/j.joen.2012.02.003_bib14","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0099-2399(97)80271-3","article-title":"The anesthetic efficacy of volumes of lidocaine in inferior alveolar nerve blocks","volume":"23","author":"Dagher","year":"1997","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib15","first-page":"41","article-title":"The inferior alveolar neurovascular bundle at the mandibular foramen","volume":"20","author":"Murphy","year":"1969","journal-title":"Dent Pract Dent Rec"},{"key":"10.1016\/j.joen.2012.02.003_bib16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.2344\/0003-3006(2008)55[2:GTAPSF]2.0.CO;2","article-title":"Gow-Gates technique: a pilot study for extraction procedures with clinical evaluation and review","volume":"55","author":"Kohler","year":"2008","journal-title":"Anesth Prog"},{"key":"10.1016\/j.joen.2012.02.003_bib17","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/BF01627882","article-title":"A tridimensional study using cuts at a low temperature of the infratemporal region","volume":"15","author":"Madrid","year":"1993","journal-title":"Surg Radiol Anat"},{"key":"10.1016\/j.joen.2012.02.003_bib18","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0099-2399(06)81125-8","article-title":"Evaluation of lidocaine in human inferior alveolar nerve block","volume":"23","author":"Yared","year":"1997","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib19","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0099-2399(97)80271-3","article-title":"An evaluation of 2% lidocaine with different concentrations of epinephrine for inferior alveolar nerve block","volume":"23","author":"Dagher","year":"1997","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib20","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.joen.2010.05.012","article-title":"Prospective, randomized single-blind study of the anesthetic efficacy of 1.8 and 3.6 milliliters of 2% lidocaine with 1:50,000 epinephrine for inferior alveolar nerve block","volume":"36","author":"Wali","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2012.02.003_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0304-3959(84)90835-2","article-title":"An experimental basis for revising the graphic rating scale for pain","volume":"19","author":"Heft","year":"1984","journal-title":"Pain"},{"key":"10.1016\/j.joen.2012.02.003_bib22","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1113\/jphysiol.1974.sp010430","article-title":"Mechanism for differential block among single myelenated nerve and non-myelenated axon by procaine","volume":"236","author":"Franz","year":"1974","journal-title":"J Physiol"},{"key":"10.1016\/j.joen.2012.02.003_bib23","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1113\/jphysiol.1974.sp010430","article-title":"Mechanisms for differential block among single myelinated and non-myelinated axons by procaine","volume":"236","author":"Franz","year":"1974","journal-title":"J Physiol"},{"key":"10.1016\/j.joen.2012.02.003_bib24","series-title":"Physiology and Pharmacology of Local Anesthesia","author":"De Jong","year":"1974"},{"key":"10.1016\/j.joen.2012.02.003_bib25","first-page":"293","article-title":"The study of the volume and shape of pterygomandibular space\u00a0by computed tomography","volume":"221","author":"Takeuchi","year":"1993","journal-title":"J Jpn Dent Soc Anesthesiol"},{"key":"10.1016\/j.joen.2012.02.003_bib26","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0030-4220(81)90001-3","article-title":"The Gow-Gates mandibular block. Evaluation after 4,275 cases","volume":"5","author":"Malamed","year":"1981","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2012.02.003_bib27","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1179\/crn.2004.030","article-title":"Reproducibility of visual analog scale (VAS) pain scores to mechanical pressure","volume":"22","author":"Goddard","year":"2004","journal-title":"Cranio"},{"key":"10.1016\/j.joen.2012.02.003_bib28","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1177\/0091270004263995","article-title":"Assessment of visual analog versus categorical scale for measurement of osteoarthritis pain","volume":"44","author":"Averbuch","year":"2004","journal-title":"J Clin Pharmacol"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239912001616?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239912001616?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T23:22:52Z","timestamp":1561418572000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239912001616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0099239912001616"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2012.02.003","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}