{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:56:47Z","timestamp":1778777807049,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.joen.2013.06.018","type":"journal-article","created":{"date-parts":[[2013,8,27]],"date-time":"2013-08-27T14:16:36Z","timestamp":1377612996000},"page":"1240-1244","source":"Crossref","is-referenced-by-count":30,"title":["Investigation of Cultivable Bacteria Isolated from Longstanding Retreatment-resistant Lesions of Teeth with\u00a0Apical Periodontitis"],"prefix":"10.1016","volume":"39","author":[{"given":"Fernanda G.C.","family":"Signoretti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda P.F.A.","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Montagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rog\u00e9rio C.","family":"Jacinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2013.06.018_bib1","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0011-8532(22)02212-1","article-title":"Principles of endodontic surgery for the general practitioner","volume":"28","author":"Gutmann","year":"1984","journal-title":"Dent Clin North Am"},{"key":"10.1016\/j.joen.2013.06.018_bib2","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1016\/j.joen.2011.09.018","article-title":"Persistent extraradicular infection in root-filled asymptomatic human tooth: scanning electron microscopic analysis and microbial investigation after apical microsurgery","volume":"37","author":"Signoretti","year":"2011","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib3","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.joen.2010.04.007","article-title":"Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings","volume":"36","author":"Ricucci","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib4","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.joen.2012.03.004","article-title":"Bacterial flora and extraradicular biofilm associated with the apical segment of teeth with post-treatment apical periodontitis","volume":"38","author":"Wang","year":"2012","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib5","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1399-302X.2009.00534.x","article-title":"Characterization of bacterial flora in persistent apical periodontitis lesions","volume":"24","author":"Fujii","year":"2009","journal-title":"Oral Microbiol Immunol"},{"key":"10.1016\/j.joen.2013.06.018_bib6","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/00004770-200210000-00001","article-title":"Participation of bacterial biofilms in refractory and chronic periapical periodontitis","volume":"28","author":"Noiri","year":"2002","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib7","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.joen.2008.06.002","article-title":"Apical actinomycosis as a continuum of intraradicular and extraradicular infection: case report and critical review on its involvement with treatment failure","volume":"34","author":"Ricucci","year":"2008","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib8","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/S0099-2399(07)80202-0","article-title":"Therapy-resistant foreign body giant cell granuloma at the periapex of a root-filled human tooth","volume":"16","author":"Nair","year":"1990","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1747-4477.1999.tb00063.x","article-title":"Cholesterol as an aetiological agent in endodontic failures\u2014a review","volume":"25","author":"Nair","year":"1999","journal-title":"Aust Endod J"},{"key":"10.1016\/j.joen.2013.06.018_bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1079-2104(96)80156-9","article-title":"Types and incidence of human periapical lesions obtained with extracted teeth","volume":"81","author":"Ramachandran Nair","year":"1996","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib11","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev.immunol.20.083001.084359","article-title":"Innate immune recognition","volume":"20","author":"Janeaway","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.joen.2013.06.018_bib12","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/ni1102-1033","article-title":"Bacterial strategies for overcoming host innate and adaptive immune responses","volume":"3","author":"Hornef","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.joen.2013.06.018_bib13","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","article-title":"Bacterial biofilms: a common cause of persistent infections","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"issue":"Suppl 6","key":"10.1016\/j.joen.2013.06.018_bib14","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1600-051X.2005.00790.x","article-title":"Dental plaque: biological significance of a biofilm and community life-style","volume":"32","author":"Marsh","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.joen.2013.06.018_bib15","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0099-2399(80)80039-2","article-title":"Incidence of periapical cysts in relation to the root canal","volume":"6","author":"Simon","year":"1980","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib16","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.joen.2009.01.024","article-title":"Histology of periapical lesions obtained during apical surgery","volume":"35","author":"Schulz","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib17","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/0030-4220(76)90217-6","article-title":"A histopathologic, histobacteriologic, and radiographic study of periapical endodontic surgical specimens","volume":"42","author":"Block","year":"1976","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2013.06.018_bib18","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0030-4220(66)90044-2","article-title":"Oral surgery\u2013oral pathology conference No. 17, Walter Reed Army Medical Center. Periapical lesions\u2013types, incidence, and clinical features","volume":"21","author":"Bhaskar","year":"1966","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2013.06.018_bib19","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/0030-4220(54)90297-2","article-title":"The value of the roentgenographic film in the differential diagnosis of periapical lesions","volume":"7","author":"Priebe","year":"1954","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2013.06.018_bib20","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0030-4220(64)90040-4","article-title":"A clinical, roentgenographic, and histopathologic evaluation of periapical lesions","volume":"17","author":"Linenberg","year":"1964","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2013.06.018_bib21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.14219\/jada.archive.1964.0056","article-title":"Periapical lesions associated with endodontically treated teeth","volume":"68","author":"Patterson","year":"1964","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2013.06.018_bib22","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0030-4220(91)90371-I","article-title":"Clinical, radiographic, and histologic study of endodontic treatment failures","volume":"71","author":"Lin","year":"1991","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.joen.2013.06.018_bib23","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.joen.2009.04.010","article-title":"Molecular analysis of persistent periradicular lesions and root ends reveals a diverse microbial profile","volume":"35","author":"Subramanian","year":"2009","journal-title":"J Endod"},{"issue":"Suppl","key":"10.1016\/j.joen.2013.06.018_bib24","first-page":"1","article-title":"Microbiological examination of root canals and periapical tissues of human teeth. Methodological studies","volume":"74","author":"Moller","year":"1966","journal-title":"Odontol Tidskr"},{"key":"10.1016\/j.joen.2013.06.018_bib25","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.0902-0055.2003.00116.x","article-title":"Microbiological examination of infected dental root canals","volume":"19","author":"Gomes","year":"2004","journal-title":"Oral Microbiol Immunol"},{"key":"10.1016\/j.joen.2013.06.018_bib26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.tripleo.2007.10.005","article-title":"Gemella morbillorum in primary and secondary\/persistent endodontic infections","volume":"105","author":"Gomes","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib27","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/00004770-200204000-00011","article-title":"Microbiota of periapical lesions refractory to endodontic treatment","volume":"28","author":"Sunde","year":"2002","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.06.018_bib28","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1601-1546.2004.00107.x","article-title":"Gram-positive organisms in endodontic infections","volume":"9","author":"Chavez de Paz","year":"2004","journal-title":"Endod Topics"},{"key":"10.1016\/j.joen.2013.06.018_bib29","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1365-2591.2004.00753.x","article-title":"Resolution of persistent periapical infection by endodontic surgery","volume":"37","author":"Ferreira","year":"2004","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2013.06.018_bib30","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1002\/ppul.20220","article-title":"How much do Pseudomonas biofilms contribute to symptoms of pulmonary exacerbation in cystic fibrosis?","volume":"39","author":"Van Devanter","year":"2005","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.joen.2013.06.018_bib31","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1006\/anae.1997.0108","article-title":"Ribotyping of bacteria from root canal and blood of patients receiving endodontic therapy","volume":"3","author":"Debelian","year":"1997","journal-title":"Anaerobe"},{"key":"10.1016\/j.joen.2013.06.018_bib32","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1902\/annals.1998.3.1.281","article-title":"Anaerobic bacteremia and fungemia in patients undergoing endodontic therapy: an overview","volume":"3","author":"Debelian","year":"1998","journal-title":"Ann Periodontol"},{"key":"10.1016\/j.joen.2013.06.018_bib33","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1399-302X.2007.00423.x","article-title":"Molecular analysis of the root canal microbiota associated with endodontic treatment failures","volume":"23","author":"Sakamoto","year":"2008","journal-title":"Oral Microbiol Immunol"},{"key":"10.1016\/j.joen.2013.06.018_bib34","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s12275-012-0459-4","article-title":"Microflora profiling of infected root canal before and after treatment using culture-independent methods","volume":"50","author":"Ito","year":"2012","journal-title":"J Microbiol"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239913005566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239913005566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T04:01:02Z","timestamp":1688443262000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239913005566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0099239913005566"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2013.06.018","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}