{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:09:39Z","timestamp":1793138979207,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.joen.2013.12.022","type":"journal-article","created":{"date-parts":[[2014,2,8]],"date-time":"2014-02-08T10:17:04Z","timestamp":1391854624000},"page":"753-758","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["Efficacy of Articaine versus Lidocaine as a Supplemental Buccal Infiltration in Mandibular Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study"],"prefix":"10.1016","volume":"40","author":[{"given":"Brandon S.","family":"Rogers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana M.","family":"Botero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neville J.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde C.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2013.12.022_bib1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cden.2009.12.003","article-title":"Local anesthesia strategies for the patient with a \u201chot\u201d tooth","volume":"54","author":"Nusstein","year":"2010","journal-title":"Dent Clin North Am"},{"key":"10.1016\/j.joen.2013.12.022_bib2","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/01.DON.0000125317.21892.8F","article-title":"Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis","volume":"30","author":"Claffey","year":"2004","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib3","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.joen.2012.01.008","article-title":"Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar","volume":"38","author":"Sampaio","year":"2012","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.joen.2008.10.020","article-title":"A comparison of the anesthetic efficacy of articaine and lidocaine in patients with irreversible pulpitis","volume":"35","author":"Tortamano","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib5","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.joen.2012.10.012","article-title":"Efficacy of articaine versus lidocaine in block and infiltration anesthesia administered in teeth with irreversible pulpitis: a prospective, randomized, double-blind study","volume":"39","author":"Ashraf","year":"2013","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.joen.2008.11.025","article-title":"Articaine for supplemental buccal mandibular infiltration anesthesia in patients with irreversible pulpitis when the inferior alveolar nerve block fails","volume":"35","author":"Matthews","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib7","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.joen.2009.04.012","article-title":"Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine after an inferior alveolar nerve block in patients with irreversible pulpitis","volume":"35","author":"Aggarwal","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib8","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0099-2399(87)80097-3","article-title":"An evaluation of an electric pulp tester as a measure of analgesia in human vital teeth","volume":"13","author":"Dreven","year":"1987","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib9","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1016\/j.tripleo.2009.06.012","article-title":"Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molar","volume":"108","author":"Fan","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib10","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.joen.2011.12.006","article-title":"A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teeth","volume":"38","author":"Kanaa","year":"2012","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/01.DON.0000140565.88940.60","article-title":"Anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in patients with irreversible pulpitis","volume":"31","author":"Nusstein","year":"2005","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib12","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0099-2399(98)80053-8","article-title":"Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis","volume":"24","author":"Nusstein","year":"1998","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.joen.2011.11.010","article-title":"A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis","volume":"38","author":"Kanaa","year":"2012","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib14","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/00004770-200310000-00004","article-title":"The significance of needle deflection in success of the inferior alveolar nerve block in patients with irreversible pulpitis","volume":"29","author":"Kennedy","year":"2003","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib15","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/00004770-200311000-00010","article-title":"Anesthetic efficacy of the supplemental X-tip intraosseous injection in patients with irreversible pulpitis","volume":"29","author":"Nusstein","year":"2003","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib16","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/S1079-2104(97)90372-3","article-title":"Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis","volume":"84","author":"Reisman","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib17","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0099-2399(98)80011-3","article-title":"Anesthetic efficacy of the supplemental intraosseous injection for teeth with irreversible pulpitis","volume":"24","author":"Parente","year":"1998","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib18","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.14219\/jada.archive.2008.0338","article-title":"Comparing anesthetic efficacy of articaine versus lidocaine as a supplemental buccal infiltration of the mandibular first molar after an inferior alveolar nerve block","volume":"139","author":"Haase","year":"2008","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2013.12.022_bib19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1365-2591.2008.01507.x","article-title":"Articaine buccal infiltration enhances the effectiveness of lidocaine inferior alveolar nerve block","volume":"42","author":"Kanaa","year":"2009","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2013.12.022_bib20","doi-asserted-by":"crossref","first-page":"493","DOI":"10.14219\/jada.archive.2011.0219","article-title":"The pulpal anesthetic efficacy of articaine versus lidocaine in dentistry: a meta-analysis","volume":"142","author":"Brandt","year":"2011","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2013.12.022_bib21","series-title":"Endodontic Glossary","year":"2012"},{"key":"10.1016\/j.joen.2013.12.022_bib22","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/01.don.0000140576.36513.cb","article-title":"A comparison of articaine and lidocaine for inferior alveolar nerve blocks","volume":"31","author":"Mikesell","year":"2005","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib23","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.14219\/jada.archive.2007.0324","article-title":"The anesthetic efficacy of articaine in buccal infiltration of mandibular posterior teeth","volume":"138","author":"Robertson","year":"2007","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2013.12.022_bib24","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.joen.2006.04.004","article-title":"Speed of injection influences efficacy of inferior alveolar nerve blocks: a double-blind randomized controlled trial in volunteers","volume":"32","author":"Kanaa","year":"2006","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib25","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.joen.2008.02.042","article-title":"Articaine infiltration for anesthesia of mandibular first molars","volume":"34","author":"Corbett","year":"2008","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib26","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.joen.2009.04.032","article-title":"Age- and gender-related differences in the position of the inferior alveolar nerve by using cone beam computed tomography","volume":"35","author":"Simonton","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib27","first-page":"293","article-title":"Clinical pharmacology and the use of articaine for local and regional anaesthesia","volume":"19","author":"Vree","year":"2005","journal-title":"Clin Anaesthiol"},{"key":"10.1016\/j.joen.2013.12.022_bib28","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0099-2399(07)80177-4","article-title":"Anatomical study of the position of the mesial roots of mandibular molars","volume":"16","author":"Frankle","year":"1990","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2013.12.022_bib29","series-title":"Handbook of Local Anaesthesia","author":"Malamed","year":"1997"},{"key":"10.1016\/j.joen.2013.12.022_bib30","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jdent.2009.12.003","article-title":"The efficacy and safety of articaine versus lignocaine in dental treatments: a meta-analysis","volume":"38","author":"Katyal","year":"2010","journal-title":"J Dent"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239913011679?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239913011679?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:45:38Z","timestamp":1758829538000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239913011679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0099239913011679"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2013.12.022","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of Articaine versus Lidocaine as a Supplemental Buccal Infiltration in Mandibular Molars with Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2013.12.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}