{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:36:46Z","timestamp":1790501806673,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 103-2314-B-006-044-MY3"],"award-info":[{"award-number":["NSC 103-2314-B-006-044-MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004844","name":"National Cheng Kung University Hospital","doi-asserted-by":"publisher","award":["NCKUH-10306013"],"award-info":[{"award-number":["NCKUH-10306013"]}],"id":[{"id":"10.13039\/501100004844","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.joen.2016.01.010","type":"journal-article","created":{"date-parts":[[2016,3,12]],"date-time":"2016-03-12T02:42:36Z","timestamp":1457750556000},"page":"711-716","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Mineralization Effect of Hyaluronan on Dental Pulp Cells via CD44"],"prefix":"10.1016","volume":"42","author":[{"given":"Kuan-Liang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Yi","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jrhau","family":"Lung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2016.01.010_bib1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0065-2776(08)60537-4","article-title":"CD44 and its interaction with extracellular matrix","volume":"54","author":"Lesley","year":"1993","journal-title":"Adv Immunol"},{"key":"10.1016\/j.joen.2016.01.010_bib2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/mp.52.4.189","article-title":"CD44 cell adhesion molecules","volume":"52","author":"Goodison","year":"1999","journal-title":"Mol Pathol"},{"key":"10.1016\/j.joen.2016.01.010_bib3","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0003-9969(01)00053-X","article-title":"The distribution pattern of the hyaluronan receptor CD44 during human tooth development","volume":"46","author":"Felszeghy","year":"2001","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.joen.2016.01.010_bib4","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.acthis.2006.06.006","article-title":"Immunolocalization of CD44s in human teeth","volume":"108","author":"Leonardi","year":"2006","journal-title":"Acta Histochem"},{"key":"10.1016\/j.joen.2016.01.010_bib5","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.joen.2012.11.043","article-title":"CD44 is involved in mineralization of dental pulp cells","volume":"39","author":"Chen","year":"2013","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2016.01.010_bib6","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1016\/j.bbagen.2014.02.001","article-title":"Hyaluronan: biosynthesis and signaling","volume":"1840","author":"Vigetti","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.joen.2016.01.010_bib7","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1034\/j.1600-0722.2000.108004311.x","article-title":"Quantitative image analysis of hyaluronan expression in human tooth germs","volume":"108","author":"Felszeghy","year":"2000","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.joen.2016.01.010_bib8","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.archoralbio.2004.10.010","article-title":"The expression pattern of hyaluronan synthase during human tooth development","volume":"50","author":"Felszeghy","year":"2005","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.joen.2016.01.010_bib9","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1177\/0022034514549809","article-title":"Tissue-engineering-based strategies for regenerative endodontics","volume":"93","author":"Albuquerque","year":"2014","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2016.01.010_bib10","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1177\/154405910708601214","article-title":"Osteogenic gene expression by human periodontal ligament cells under cyclic tension","volume":"86","author":"Wescott","year":"2007","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2016.01.010_bib11","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/jre.12170","article-title":"Importance of CD44 in the proliferation and mineralization of periodontal ligament cells","volume":"49","author":"Yeh","year":"2014","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.joen.2016.01.010_bib12","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1039\/B910552M","article-title":"Therapeutic applications of hyaluronan","volume":"6","author":"Gaffney","year":"2010","journal-title":"Mol BioSyst"},{"key":"10.1016\/j.joen.2016.01.010_bib13","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1002\/jbm.a.10535","article-title":"The effect of hyaluronan on osteoblast proliferation and differentiation in rat calvarial-derived cell culture","volume":"66","author":"Huang","year":"2003","journal-title":"J Biomed Mater Res A"},{"key":"10.1016\/j.joen.2016.01.010_bib14","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1359\/jbmr.070417","article-title":"LIF inhibits osteoblast differentiation at least in part by regulation of HAS2 and its product hyaluronan","volume":"22","author":"Falconi","year":"2007","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.joen.2016.01.010_bib15","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/dvdy.22529","article-title":"Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development","volume":"240","author":"Moffat","year":"2011","journal-title":"Dev Dyn"},{"key":"10.1016\/j.joen.2016.01.010_bib16","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0003-9969(95)98810-L","article-title":"Providing an environment for reparative dentine induction in amputated rat molar pulp by high molecular-weight hyaluronic acid","volume":"40","author":"Sasaki","year":"1995","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.joen.2016.01.010_bib17","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/jbm.b.31497","article-title":"Effects of hyaluronic acid sponge as a scaffold on odontoblastic cell line and amputated dental pulp","volume":"92","author":"Inuyama","year":"2010","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.joen.2016.01.010_bib18","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1177\/0022034513490958","article-title":"Compounded PHOSPHO1\/ALPL deficiencies reduce dentin mineralization","volume":"92","author":"McKee","year":"2013","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2016.01.010_bib19","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1177\/00220345980770040701","article-title":"Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development","volume":"77","author":"Helder","year":"1998","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2016.01.010_bib20","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.joen.2007.03.010","article-title":"Adenovirus-mediated recombinant human bone morphogenetic protein-7 expression promotes differentiation of human dental pulp cells","volume":"33","author":"Lin","year":"2007","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2016.01.010_bib21","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1177\/0022034511408426","article-title":"Induced migration of dental pulp stem cells for in\u00a0vivo pulp regeneration","volume":"90","author":"Suzuki","year":"2011","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2016.01.010_bib22","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0003-9969(01)00100-5","article-title":"Differential repair responses in the coronal and radicular areas of the exposed rat molar pulp induced by recombinant human bone morphogenetic protein 7 (osteogenic protein 1)","volume":"47","author":"Six","year":"2002","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.joen.2016.01.010_bib23","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0945-053X(01)00187-1","article-title":"Developmentally regulated expression of type XV collagen correlated with abnormalities in Col15a1 (-\/-) mice","volume":"21","author":"Muona","year":"2002","journal-title":"Matrix Biol"},{"key":"10.1016\/j.joen.2016.01.010_bib24","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.bbrc.2005.04.118","article-title":"Molecular markers distinguish bone marrow mesenchymal stem cells from fibroblasts","volume":"332","author":"Ishii","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.joen.2016.01.010_bib25","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/jcp.21779","article-title":"Gene array profile identified collagen type XV as a novel human osteoblast-secreted matrix protein","volume":"220","author":"Lisignoli","year":"2009","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.joen.2016.01.010_bib26","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1096\/fasebj.7.13.7691670","article-title":"Hyaluronan-binding proteins in development, tissue homeostasis, and disease","volume":"7","author":"Knudson","year":"1993","journal-title":"FASEB J"},{"key":"10.1016\/j.joen.2016.01.010_bib27","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10529-006-9219-z","article-title":"Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications","volume":"29","author":"Kogan","year":"2007","journal-title":"Biotechnol Lett"},{"key":"10.1016\/j.joen.2016.01.010_bib28","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/j.1460-2075.1991.tb07955.x","article-title":"The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells","volume":"10","author":"Stamenkovic","year":"1991","journal-title":"EMBO J"},{"key":"10.1016\/j.joen.2016.01.010_bib29","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1083\/jcb.131.6.1623","article-title":"Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons","volume":"131","author":"Bennett","year":"1995","journal-title":"J Cell Biol"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239916000625?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239916000625?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:46:11Z","timestamp":1758829571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239916000625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S0099239916000625"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2016.01.010","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mineralization Effect of Hyaluronan on Dental Pulp Cells via CD44","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2016.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}