{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:18:33Z","timestamp":1791832713724,"version":"4.3.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004035","name":"Jordan University of Science and Technology","doi-asserted-by":"publisher","award":["154\/2013"],"award-info":[{"award-number":["154\/2013"]}],"id":[{"id":"10.13039\/501100004035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.joen.2018.08.004","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T20:26:03Z","timestamp":1538598363000},"page":"1603-1609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":132,"title":["Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine: A Prospective Randomized Clinical Trial"],"prefix":"10.1016","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0031-2229","authenticated-orcid":false,"given":"Lama","family":"Awawdeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aladdin","family":"Al-Qudah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan","family":"Hamouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalie Jean","family":"Chakra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2018.08.004_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.joen.2008.02.030","article-title":"Vital pulp therapy with new materials: new directions and treatment perspectives in permanent teeth","volume":"34","author":"Witherspoon","year":"2008","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.joen.2016.12.028","article-title":"Higher maximal occlusal bite force in endodontically treated teeth versus vital contralateral counterparts","volume":"43","author":"Awawdeh","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib3","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.joen.2010.12.004","article-title":"Vital pulp therapy in vital permanent teeth with cariously exposed pulp: a systematic review","volume":"37","author":"Aguilar","year":"2011","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.joen.2009.09.029","article-title":"AAE consensus conference on diagnostic terminology: background and perspectives","volume":"35","author":"Glickman","year":"2009","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib5","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00784-014-1244-z","article-title":"Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial","volume":"19","author":"Asgary","year":"2015","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.joen.2018.08.004_bib6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0099-2399(96)80017-3","article-title":"A clinical study of direct pulp capping applied to carious-exposed pulps","volume":"22","author":"Matsuo","year":"1996","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib7","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/iej.12719","article-title":"Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide","volume":"50","author":"Kundzina","year":"2017","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib8","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/j.joen.2014.08.010","article-title":"Correlation between clinical and histologic pulp diagnosis","volume":"40","author":"Ricucci","year":"2014","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib9","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1365-2591.2012.02016.x","article-title":"Diagnosis of the condition of the dental pulp: a systematic review","volume":"45","author":"Mejare","year":"2012","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib10","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2591.2012.02113.x","article-title":"Should pulp chamber pulpotomy be seen as a permanent treatment? Some preliminary thoughts","volume":"46","author":"Simon","year":"2013","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib11","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.joen.2017.12.010","article-title":"Treatment outcomes of 4 vital pulp therapies in mature molars","volume":"44","author":"Asgary","year":"2018","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.joen.2009.09.006","article-title":"Mineral trioxide aggregate: a comprehensive literature review\u2014part i: chemical, physical, and antibacterial properties","volume":"36","author":"Parirokh","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib13","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1016\/j.joen.2014.07.019","article-title":"Treatment outcome of mineral trioxide aggregate or calcium hydroxide direct pulp capping: long-term results","volume":"40","author":"Mente","year":"2014","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib14","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/iej.12843","article-title":"Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part II: other clinical applications and complications","volume":"51","author":"Torabinejad","year":"2018","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s40368-014-0114-3","article-title":"Biodentine\u2122 material characteristics and clinical applications: a review of the literature","volume":"15","author":"Rajasekharan","year":"2014","journal-title":"Eur Arch Paediatr Dent"},{"key":"10.1016\/j.joen.2018.08.004_bib16","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/iej.12231","article-title":"Comparison of pulp response to mineral trioxide aggregate and a bioceramic paste in partial pulpotomy of sound human premolars: a randomized controlled trial","volume":"47","author":"Azimi","year":"2014","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.joen.2017.10.012","article-title":"Outcomes of direct pulp capping by using either ProRoot mineral trioxide aggregate or biodentine in permanent teeth with carious pulp exposure in 6- to 18-year-old patients: a randomized controlled trial","volume":"44","author":"Parinyaprom","year":"2018","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib18","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.joen.2016.11.026","article-title":"Comparative analysis of 2 calcium silicate -based cements (Biodentine and mineral trioxide aggregate) as direct pulp-capping agent in young permanent molars: a split mouth study","volume":"43","author":"Katge","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib19","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.joen.2017.06.031","article-title":"Direct pulp capping with calcium hydroxide, mineral trioxide aggregate, and Biodentine in permanent young teeth with caries: a randomized clinical trial","volume":"43","author":"Brizuela","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib20","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1365-2591.2006.01101.x","article-title":"The influence of haemostatic agents on healing of healthy human dental pulp tissue capped with calcium hydroxide","volume":"39","author":"Silva","year":"2006","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib21","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/iej.12619","article-title":"Efficacy of three different pulpotomy agents in primary molars: a randomized control trial","volume":"50","author":"Rajasekharan","year":"2017","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib22","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.joen.2014.02.006","article-title":"Comparison of pulpal responses to pulpotomy and pulp capping with Biodentine and mineral trioxide aggregate in dogs","volume":"40","author":"De Rossi","year":"2014","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2018.08.004_bib23","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1177\/0022034512460833","article-title":"Effect of a calcium-silicate-based restorative cement on pulp repair","volume":"91","author":"Tran","year":"2012","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2018.08.004_bib24","first-page":"35","article-title":"Biodentine a promising bioactive material for the preservation of pulp vitality in restorative dentistry","volume":"4","author":"Bakopoulou","year":"2015","journal-title":"Int Dent Afr"},{"key":"10.1016\/j.joen.2018.08.004_bib25","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1177\/0022034515571415","article-title":"Clinical and radiographic assessment of the efficacy of calcium silicate indirect pulp capping: a randomized controlled clinical trial","volume":"94","author":"Hashem","year":"2015","journal-title":"J Dent Res"},{"key":"10.1016\/j.joen.2018.08.004_bib26","first-page":"140","article-title":"Biodentine: a promising dentin substitute","volume":"2","author":"Singh","year":"2014","journal-title":"J Interdiscipl Med Dent Sci"},{"key":"10.1016\/j.joen.2018.08.004_bib27","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.dental.2013.03.007","article-title":"Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine\u2122 and MTA Angelus","volume":"29","author":"Camilleri","year":"2013","journal-title":"Dent Mater"},{"key":"10.1016\/j.joen.2018.08.004_bib28","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1111\/iej.12793","article-title":"Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs","volume":"50","author":"Wolters","year":"2017","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib29","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1747-4477.2009.00166.x","article-title":"MTA pulpotomy of human permanent molars with irreversible pulpitis","volume":"35","author":"Mohammad","year":"2009","journal-title":"Aust Endod J"},{"key":"10.1016\/j.joen.2018.08.004_bib30","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/0030-4220(89)90252-1","article-title":"Pulp capping: conserving the dental pulp-can it work? Is it worth it?","volume":"68","author":"Stanley","year":"1989","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.joen.2018.08.004_bib31","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1590\/S1678-77572005000100015","article-title":"Influence of the restoration quality on the success of pulpotomy treatment: a preliminary retrospective study","volume":"13","author":"Demarco","year":"2005","journal-title":"J Appl Oral Sci"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239918305508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239918305508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:46:27Z","timestamp":1758829587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239918305508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S0099239918305508"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2018.08.004","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine: A Prospective Randomized Clinical Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2018.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}