{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:59:22Z","timestamp":1791223162892,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.joen.2022.11.005","type":"journal-article","created":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T20:28:50Z","timestamp":1668198530000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["Outcome of Direct Pulp Capping Using Calcium Hydroxide: A Long-term Retrospective Study"],"prefix":"10.1016","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0637-6722","authenticated-orcid":false,"given":"Domenico","family":"Ricucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela N.","family":"R\u00f4\u00e7as","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio R.F.","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro H.","family":"Cabello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Jos\u00e9 F.","family":"Siqueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2022.11.005_bib1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1600-9657.1987.tb00619.x","article-title":"Tissue response to dental caries","volume":"3","author":"Langeland","year":"1987","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.joen.2022.11.005_bib2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jdent.2019.05.022","article-title":"Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure","volume":"86","author":"Ricucci","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib3","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.tripleo.2011.08.003","article-title":"A prospective cohort study of endodontic treatments of 1,369 root canals: results after 5 years","volume":"112","author":"Ricucci","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib4","series-title":"Cohen's pathways of the pulp","first-page":"652","article-title":"Evaluation of Outcomes","author":"Ng","year":"2021"},{"key":"10.1016\/j.joen.2022.11.005_bib5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/00004770-200009000-00010","article-title":"Pulp capping of carious exposures: treatment outcome after 5 and 10 years: a retrospective study","volume":"26","author":"Barthel","year":"2000","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib6","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1600-0722.2010.00731.x","article-title":"Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy","volume":"118","author":"Bj\u00f8rndal","year":"2010","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.joen.2022.11.005_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1601-1546.2003.00030.x","article-title":"Vital pulp therapy for the mature tooth \u2013 can it work?","volume":"5","author":"Swift","year":"2003","journal-title":"Endod Top"},{"key":"10.1016\/j.joen.2022.11.005_bib8","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.joen.2015.02.024","article-title":"Outcome of direct pulp capping with mineral trioxide aggregate: a prospective study","volume":"41","author":"Marques","year":"2015","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib9","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.joen.2015.04.012","article-title":"Direct pulp capping with calcium hydroxide or mineral trioxide aggregate: a meta-analysis","volume":"41","author":"Li","year":"2015","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib10","article-title":"Vital pulp therapy in permanent mature posterior teeth with symptomatic irreversible pulpitis: a systematic review of treatment outcomes","volume":"57","author":"Santos","year":"2021","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.joen.2022.11.005_bib11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.cden.2010.03.001","article-title":"Clinical threshold for carious tissue removal","volume":"54","author":"Kidd","year":"2010","journal-title":"Dent Clin North Am"},{"key":"10.1016\/j.joen.2022.11.005_bib12","doi-asserted-by":"crossref","first-page":"103430","DOI":"10.1016\/j.jdent.2020.103430","article-title":"Pulp and dentine responses to selective caries excavation: a histological and histobacteriological human study","volume":"100","author":"Ricucci","year":"2020","journal-title":"J Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib13","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0099-2399(96)80017-3","article-title":"A clinical study of direct pulp capping applied to carious-exposed pulps","volume":"22","author":"Matsuo","year":"1996","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib14","doi-asserted-by":"crossref","first-page":"305","DOI":"10.14219\/jada.archive.2008.0160","article-title":"Direct pulp capping with mineral trioxide aggregate: an observational study","volume":"139","author":"Bogen","year":"2008","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2022.11.005_bib15","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.joen.2010.02.024","article-title":"Mineral trioxide aggregate or calcium hydroxide direct pulp capping: an analysis of the clinical treatment outcome","volume":"36","author":"Mente","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib16","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.joen.2010.12.004","article-title":"Vital pulp therapy in vital permanent teeth with cariously exposed pulp: a systematic review","volume":"37","author":"Aguilar","year":"2011","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib17","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.joen.2016.10.027","article-title":"Treatment outcomes of mineral trioxide aggregate pulpotomy in vital permanent teeth with carious pulp exposure: the retrospective study","volume":"43","author":"Linsuwanont","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib18","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.joen.2017.12.010","article-title":"Treatment outcomes of 4 vital pulp therapies in mature molars","volume":"44","author":"Asgary","year":"2018","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib19","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/j.joen.2017.03.033","article-title":"Partial Pulpotomy in Mature Permanent Teeth with Clinical Signs Indicative of Irreversible Pulpitis: A Randomized Clinical Trial","volume":"43","author":"Taha","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib20","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/iej.13071","article-title":"Partial pulpotomy with two bioactive cements in permanent teeth of 6- to 18-year-old patients with signs and symptoms indicative of irreversible pulpitis: a noninferiority randomized controlled trial","volume":"52","author":"Uesrichai","year":"2019","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2022.11.005_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdent.2019.03.010","article-title":"Pulpotomy for carious pulp exposures in permanent teeth: a systematic review and meta-analysis","volume":"84","author":"Li","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib22","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/iej.13080","article-title":"European Society of Endodontology position statement: management of deep caries and the exposed pulp","volume":"52","year":"2019","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2022.11.005_bib23","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.joen.2021.07.015","article-title":"AAE Position Statement on Vital Pulp Therapy","volume":"47","year":"2021","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib24","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00784-014-1244-z","article-title":"Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial","volume":"19","author":"Asgary","year":"2015","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.joen.2022.11.005_bib25","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1365-2591.1998.00147.x","article-title":"Reparative hard tissue formation following calcium hydroxide application after partial pulpotomy in cariously exposed pulps of permanent teeth","volume":"31","author":"Nosrat","year":"1998","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2022.11.005_bib26","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/iej.12225","article-title":"Randomized control trial comparing calcium hydroxide and mineral trioxide aggregate for partial pulpotomies in cariously exposed pulps of permanent molars","volume":"47","author":"Chailertvanitkul","year":"2014","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2022.11.005_bib27","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/j.joen.2017.08.007","article-title":"Comparative evaluation of postoperative pain and success rate after pulpotomy and root canal treatment in cariously exposed mature permanent molars: a randomized controlled trial","volume":"43","author":"Galani","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2022.11.005_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdent.2015.12.005","article-title":"Coronal pulpotomy for cariously exposed permanent posterior teeth with closed apices: a systematic review and meta-analysis","volume":"44","author":"Alqaderi","year":"2016","journal-title":"J Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib29","first-page":"17055","article-title":"Clinical outcome of direct pulp capping with MTA or calcium hydroxide: a systematic review and meta-analysis","volume":"8","author":"Zhu","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"10.1016\/j.joen.2022.11.005_bib30","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF03262577","article-title":"Calcium hydroxide vs mineral trioxide aggregates for partial pulpotomy of permanent molars with deep caries","volume":"8","author":"Qudeimat","year":"2007","journal-title":"Eur Arch Paediatr Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib31","first-page":"399","article-title":"Comparison of mineral trioxide aggregate and calcium hydroxide as pulpotomy agents in young permanent teeth (apexogenesis)","volume":"28","author":"El-Meligy","year":"2006","journal-title":"Pediatr Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib32","first-page":"364","article-title":"Partial Pulpotomy in Immature Permanent Molars after Carious Exposures Using Different Hemorrhage Control and Capping Materials","volume":"39","author":"\u00d6zg\u00fcr","year":"2017","journal-title":"Pediatr Dent"},{"key":"10.1016\/j.joen.2022.11.005_bib33","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1600-9657.1985.tb00555.x","article-title":"A retrospective study of direct pulp capping with calcium hydroxide compounds","volume":"1","author":"H\u00f8rsted","year":"1985","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.joen.2022.11.005_bib34","doi-asserted-by":"crossref","first-page":"472","DOI":"10.14219\/jada.archive.1979.0317","article-title":"Permeability of the hard tissue bridge formed after pulpotomy with calcium hydroxide: a histologic study","volume":"99","author":"Holland","year":"1979","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2022.11.005_bib35","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.jdent.2014.06.012","article-title":"Is hard tissue formation in the dental pulp after the death of the primary odontoblasts a regenerative or a reparative process?","volume":"42","author":"Ricucci","year":"2014","journal-title":"J Dent"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239922007543?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239922007543?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:53:46Z","timestamp":1758830026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239922007543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S0099239922007543"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2022.11.005","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcome of Direct Pulp Capping Using Calcium Hydroxide: A Long-term Retrospective Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2022.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}