{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:46:42Z","timestamp":1793148402826,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.joen.2023.07.024","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T20:37:31Z","timestamp":1691440651000},"page":"1421-1431","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["The Link Between Apical Periodontitis and Gastrointestinal Diseases\u2014A Systematic Review"],"prefix":"10.1016","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6512-4934","authenticated-orcid":false,"given":"Aleksandar","family":"Jakovljevic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Ideo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Jacimovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Aminoshariae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkateshbabu","family":"Nagendrababu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Azarpazhooh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Cotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2023.07.024_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1600-0757.1997.tb00098.x","article-title":"Apical periodontitis: a dynamic encounter between root canal infection and host response","volume":"13","author":"Nair","year":"1997","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.joen.2023.07.024_bib2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.joen.2013.10.036","article-title":"Overlapping protective and destructive regulatory pathways in apical periodontitis","volume":"40","author":"M\u00e1rton","year":"2014","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib3","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.joen.2010.04.007","article-title":"Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings","volume":"36","author":"Ricucci","year":"2010","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib4","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1590\/1807-3107bor-2018.vol32.0069","article-title":"Etiologic role of root canal infection in apical periodontitis and its relationship with clinical symptomatology","volume":"32","author":"Gomes","year":"2018","journal-title":"Braz Oral Res"},{"key":"10.1016\/j.joen.2023.07.024_bib5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1365-2591.2006.01099.x","article-title":"On the causes of persistent apical periodontitis: a review","volume":"39","author":"Nair","year":"2006","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib6","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1177\/154411130401500604","article-title":"Pathogenesis of apical periodontitis and the causes of endodontic failures","volume":"15","author":"Nair","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.joen.2023.07.024_bib7","first-page":"CD005511","article-title":"Endodontic procedures for retreatment of periapical lesions","volume":"10","author":"Del Fabbro","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.joen.2023.07.024_bib8","doi-asserted-by":"crossref","first-page":"144","DOI":"10.4103\/1305-7456.175682","article-title":"Failure of endodontic treatment: The usual suspects","volume":"10","author":"Tabassum","year":"2016","journal-title":"Eur J Dent"},{"key":"10.1016\/j.joen.2023.07.024_bib9","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.joen.2020.07.007","article-title":"Prevalence of apical periodontitis and conventional nonsurgical root canal treatment in general adult population: an updated systematic review and meta-analysis of cross-sectional studies published between 2012 and 2020","volume":"46","author":"Jakovljevic","year":"2020","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib10","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/j.joen.2019.07.017","article-title":"Apical periodontitis is associated with elevated concentrations of inflammatory mediators in peripheral blood: a systematic review and meta-analysis","volume":"45","author":"Georgiou","year":"2019","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib11","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/iej.12507","article-title":"Endodontic medicine: connections between apical periodontitis and systemic diseases","volume":"48","author":"Segura-Egea","year":"2015","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib12","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/j.joen.2016.07.007","article-title":"Association between systemic diseases and apical periodontitis","volume":"42","author":"Khalighinejad","year":"2016","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib13","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/iej.13079","article-title":"Endodontics and diabetes: association versus causation","volume":"52","author":"Segura-Egea","year":"2019","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib14","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.joen.2016.11.004","article-title":"Prevalence of apical periodontitis in patients with inflammatory bowel diseases: a retrospective clinical study","volume":"43","author":"Piras","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib15","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.joen.2018.09.004","article-title":"Healing of apical periodontitis in patients with inflammatory bowel diseases and under anti-tumor necrosis factor alpha therapy","volume":"44","author":"Cotti","year":"2018","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib16","first-page":"155","article-title":"Association between rheumatoid arthritis and apical periodontitis: a cross-sectional study","volume":"5","author":"Karata\u015f","year":"2020","journal-title":"Eur Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib17","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1111\/iej.13364","article-title":"Association between cardiovascular diseases and apical periodontitis: an umbrella review","volume":"53","author":"Jakovljevic","year":"2020","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib18","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.joen.2015.01.037","article-title":"Endodontic infection and endothelial dysfunction are associated with different mechanisms in men and women","volume":"41","author":"Cotti","year":"2015","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib19","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.joen.2017.04.014","article-title":"Association of end-stage renal disease with radiographically and clinically diagnosed apical periodontitis: a hospital-based study","volume":"43","author":"Khalighinejad","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib20","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/iej.13538","article-title":"The association between apical periodontitis and adverse pregnancy outcomes: a systematic review","volume":"54","author":"Jakovljevic","year":"2021","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/iej.13789","article-title":"Impact of systemic health on treatment outcomes in endodontics","volume":"56","author":"Segura-Egea","year":"2023","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.tripleo.2004.06.065","article-title":"Factors affecting the outcome of orthograde root canal therapy in a general dentistry hospital practice","volume":"99","author":"Marending","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib23","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/iej.13756","article-title":"Single nucleotide polymorphisms as a predisposing factor for the development of apical periodontitis-An umbrella review","volume":"55","author":"Jakovljevic","year":"2022","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib24","series-title":"Handbook of Functional Gastrointestinal Disorders","author":"Olden","year":"1996"},{"key":"10.1016\/j.joen.2023.07.024_bib25","article-title":"Dysbiosis of the gut microbiota in disease","volume":"26","author":"Carding","year":"2015","journal-title":"Microb Ecol Health Dis"},{"key":"10.1016\/j.joen.2023.07.024_bib26","doi-asserted-by":"crossref","first-page":"200","DOI":"10.20452\/pamw.1256","article-title":"Proinflammatory cytokines in the saliva of patients with active and non-active Crohn's disease","volume":"122","author":"Szczeklik","year":"2012","journal-title":"Pol Arch Med Wewn"},{"key":"10.1016\/j.joen.2023.07.024_bib27","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1365-2249.2004.02394.x","article-title":"Serum and salivary IgA antibody responses to Saccharomyces cerevisiae, Candida albicans and Streptococcus mutans in orofacial granulomatosis and Crohn's disease","volume":"135","author":"Savage","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.joen.2023.07.024_bib28","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3390\/jcm8060889","article-title":"Saliva and serum immune responses in apical periodontitis","volume":"8","author":"Pieti\u00e4inen","year":"2019","journal-title":"J Clin Med"},{"key":"10.1016\/j.joen.2023.07.024_bib29","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1128\/iai.53.3.671-677.1986","article-title":"Potential role of microorganisms isolated from periodontal lesions in the pathogenesis of inflammatory bowel disease","volume":"53","author":"Van Dyke","year":"1986","journal-title":"Infect Immun"},{"key":"10.1016\/j.joen.2023.07.024_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep00332","article-title":"Infection of specific strains of Streptococcumutans, oral bacteria, confers a risk of ulcerative colitis","volume":"2","author":"Kojima","year":"2012","journal-title":"Sci Rep"},{"key":"10.1016\/j.joen.2023.07.024_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.649925","article-title":"Systemic and extraradicular bacterial translocation in apical periodontitis","volume":"11","author":"Bordagaray","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.joen.2023.07.024_bib32","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/ibd\/izz128","article-title":"High prevalence of apical periodontitis in patients with inflammatory bowel disease: an age- and gender- matched case-control study","volume":"26","author":"Poyato-Borrego","year":"2020","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.joen.2023.07.024_bib33","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/jgh3.12489","article-title":"The impact of oral diseases in cirrhosis on complications and mortality","volume":"5","author":"Gr\u00f8nkj\u00e6r","year":"2021","journal-title":"JGH Open"},{"key":"10.1016\/j.joen.2023.07.024_bib34","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/iej.13747","article-title":"Periapical and endodontic status of patients with inflammatory bowel disease: Age- and sex-matched case-control study","volume":"55","author":"Segura-Sampedro","year":"2022","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.1020126","article-title":"Patients with inflammatory bowel disease have a higher chance of developing periodontitis: A systematic review and meta-analysis","volume":"9","author":"Domokos","year":"2022","journal-title":"Front Med"},{"key":"10.1016\/j.joen.2023.07.024_bib36","article-title":"The association between periodontitis and inflammatory bowel disease: a systematic review and meta-analysis","volume":"2021","author":"Zhang","year":"2021","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.joen.2023.07.024_bib37","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12903-020-1053-5","article-title":"Periodontitis and inflammatory bowel disease: a meta-analysis","volume":"20","author":"She","year":"2020","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.joen.2023.07.024_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph182111521","article-title":"Oral health status in patients with inflammatory bowel diseases: a systematic review","volume":"18","author":"Nijakowski","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.joen.2023.07.024_bib39","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1080\/00016357.2020.1859132","article-title":"Association between periodontal disease and inflammatory bowel disease: a systematic review and meta-analysis","volume":"79","author":"Lorenzo-Pouso","year":"2021","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.joen.2023.07.024_bib40","doi-asserted-by":"crossref","DOI":"10.1177\/2050312115601122","article-title":"Periodontal disease and liver cirrhosis: a systematic review","volume":"3","author":"Gr\u00f8nkj\u00e6r","year":"2015","journal-title":"SAGE Open Med"},{"key":"10.1016\/j.joen.2023.07.024_bib41","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.joen.2023.07.024_bib42","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jclinepi.2016.01.021","article-title":"PRESS peer review of electronic search strategies: 2015 guideline statement","volume":"75","author":"McGowan","year":"2016","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.joen.2023.07.024_bib43","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13643-020-01542-z","article-title":"PRISMA-S: an extension to the PRISMA statement for reporting literature searches in systematic reviews","volume":"10","author":"Rethlefsen","year":"2021","journal-title":"Syst Rev"},{"key":"10.1016\/j.joen.2023.07.024_bib44","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan-a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst Rev"},{"key":"10.1016\/j.joen.2023.07.024_bib45","author":"Wells"},{"key":"10.1016\/j.joen.2023.07.024_bib46","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.joen.2022.02.008","article-title":"Prevalence of apical periodontitis in patients with autoimmune diseases under immunomodulators: a retrospective cohort study","volume":"48","author":"Ideo","year":"2022","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib47","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2147\/HMER.S113485","article-title":"Presence and consequence of tooth periapical radiolucency in patients with cirrhosis","volume":"8","author":"Gr\u00f8nkj\u00e6r","year":"2016","journal-title":"Hepat Med"},{"key":"10.1016\/j.joen.2023.07.024_bib48","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1600-9657.1986.tb00119.x","article-title":"The periapical index: a scoring system for radiographic assessment of apical periodontitis","volume":"2","author":"Orstavik","year":"1986","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.joen.2023.07.024_bib49","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1046\/j.1365-2591.2000.00295.x","article-title":"Periapical health related to the quality of root canal treatment in a Belgian population","volume":"33","author":"De Moor","year":"2000","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib50","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2591.2011.01872.x","article-title":"A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health","volume":"44","author":"Ng","year":"2011","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib51","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies","volume":"390","author":"Ng","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.joen.2023.07.024_bib52","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1159\/000456580","article-title":"Lessons from epidemiology: the burden of liver disease","volume":"35","author":"Rowe","year":"2017","journal-title":"Dig Dis"},{"key":"10.1016\/j.joen.2023.07.024_bib53","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/prd.12427","article-title":"Periodontitis, chronic liver diseases, and the emerging oral-gut-liver axis","volume":"89","author":"Albuquerque-Souza","year":"2022","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.joen.2023.07.024_bib54","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s10266-021-00636-x","article-title":"Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions","volume":"109","author":"Cintra","year":"2021","journal-title":"Odontology"},{"key":"10.1016\/j.joen.2023.07.024_bib55","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1159\/000519170","article-title":"Dental caries occurrence in inflammatory bowel disease patients: a systematic review and meta-analysis","volume":"55","author":"Marruganti","year":"2021","journal-title":"Caries Res"},{"key":"10.1016\/j.joen.2023.07.024_bib56","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.joen.2020.05.020","article-title":"The apical root canal system of teeth with posttreatment apical periodontitis: correlating microbiologic, tomographic, and histopathologic findings","volume":"46","author":"Siqueira","year":"2020","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib57","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.immuni.2021.12.012","article-title":"Metabolic adaptation of lymphocytes in immunity and disease","volume":"55","author":"Chapman","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.joen.2023.07.024_bib58","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1016\/j.joen.2017.06.019","article-title":"The influence of adalimumab on the healing of apical periodontitis in ferrets","volume":"43","author":"Cotti","year":"2017","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2023.07.024_bib59","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1111\/iej.13501","article-title":"Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology (ESE) S3 level clinical practice guidelines: a protocol","volume":"54","author":"Duncan","year":"2021","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib60","doi-asserted-by":"crossref","first-page":"7963","DOI":"10.3748\/wjg.v22.i35.7963","article-title":"Periodontal and inflammatory bowel diseases: is there evidence of complex pathogenic interactions?","volume":"22","author":"Lira-Junior","year":"2016","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.joen.2023.07.024_bib61","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/iej.13786","article-title":"The impact of apical periodontitis, non-surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers","volume":"5","author":"Bakhsh","year":"2022","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib62","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/iej.13444","article-title":"Impact of root canal treatment on high-sensitivity C-reactive protein levels in systemically healthy adults with apical periodontitis - a preliminary prospective, longitudinal interventional study","volume":"54","author":"Poornima","year":"2021","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2023.07.024_bib63","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3390\/dj10020016","article-title":"Oral health and liver disease: bidirectional associations-a narrative review","volume":"10","author":"\u00c5berg","year":"2022","journal-title":"Dent J"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239923004685?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239923004685?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T19:55:21Z","timestamp":1758830121000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239923004685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":63,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S0099239923004685"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2023.07.024","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Link Between Apical Periodontitis and Gastrointestinal Diseases\u2014A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2023.07.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}