{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:41:12Z","timestamp":1792806072773,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.joen.2026.08.028","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T08:45:37Z","timestamp":1787388337000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Apical Periodontitis: A Hidden Non-Communicable Disease in Global Health - A Narrative Review of Longitudinal Research"],"prefix":"10.1016","author":[{"given":"Sadia Ambreen","family":"Niazi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2026.08.028_bib1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1177\/154411130401500604","article-title":"Pathogenesis of apical periodontitis and the causes of endodontic failures","volume":"15","author":"Nair","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.joen.2026.08.028_bib2","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1111\/iej.14125","article-title":"The immune landscape in apical periodontitis: From mechanism to therapy","volume":"57","author":"Wen","year":"2024","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib3","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/iej.12710","article-title":"Association between apical periodontitis and cardiovascular diseases: a systematic review of the literature","volume":"50","author":"Berlin-Broner","year":"2017","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib4","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3390\/jcm9020540","article-title":"Apical periodontitis and diabetes mellitus type 2: a systematic review and meta-analysis","volume":"9","author":"P\u00e9rez-Losada","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.joen.2026.08.028_bib5","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/j.joen.2016.07.007","article-title":"Association between systemic diseases and apical periodontitis","volume":"42","author":"Khalighinejad","year":"2016","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib6","series-title":"Global oral health status report: towards universal health coverage for oral health by 2030","author":"World Health Organization","year":"2022"},{"key":"10.1016\/j.joen.2026.08.028_bib7","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.identj.2024.11.022","article-title":"Global and regional patterns in edentulism (1990-2021) with predictions to 2040","volume":"75","author":"Chen","year":"2025","journal-title":"Int Dental J"},{"key":"10.1016\/j.joen.2026.08.028_bib8","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/iej.13467","article-title":"The global prevalence of apical periodontitis: a systematic review and meta-analysis","volume":"54","author":"Tib\u00farcio-Machado","year":"2021","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib9","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/jcpe.13769","article-title":"Prevalence of periodontitis in dentate people between 2011 and 2020: a systematic review and meta-analysis of epidemiological studies","volume":"50","author":"Trindade","year":"2023","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.joen.2026.08.028_bib10","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1186\/s12903-025-05724-w","article-title":"Systematic review and meta-analysis of the prevalence of oral cancer in Nigeria","volume":"25","author":"Nwaozuru","year":"2025","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.joen.2026.08.028_bib11","series-title":"Dental Caries (Tooth Decay) in Adults (Ages 20 to 64 Years)","year":"2022"},{"key":"10.1016\/j.joen.2026.08.028_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jebdp.2021.101667","article-title":"Limited evidence shows a high global burden of apical periodontitis among adults worldwide","volume":"22","author":"Jakovljevic","year":"2022","journal-title":"J Evid Based Dent Pract"},{"key":"10.1016\/j.joen.2026.08.028_bib13","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/iej.13253","article-title":"Association between diabetes and the outcome of root canal treatment in adults: an umbrella review","volume":"53","author":"Nagendrababu","year":"2020","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib14","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1111\/iej.13979","article-title":"Successful endodontic treatment reduces serum levels of cardiovascular disease risk biomarkers-high-sensitivity C-reactive protein, asymmetric dimethylarginine, and matrix metalloprotease-2","volume":"56","author":"Al-Abdulla","year":"2023","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib15","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/iej.14184","article-title":"Apical periodontitis microbiome association with salivary and serum inflammatory burden","volume":"58","author":"Bakhsh","year":"2025","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib16","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.joen.2024.11.009","article-title":"Links between nosocomial endodontic infections and bacteraemia associated with apical periodontitis and endodontic treatment","volume":"51","author":"Bakhsh","year":"2024","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib17","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/iej.13786","article-title":"The impact of apical periodontitis, non-surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers","volume":"55","author":"Bakhsh","year":"2022","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/prca.201900060","article-title":"A systematic review of the root canal microbiota associated with apical periodontitis: lessons from next-generation sequencing","volume":"14","author":"Manoil","year":"2020","journal-title":"Proteomics Clin Appl"},{"key":"10.1016\/j.joen.2026.08.028_bib19","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1111\/iej.14071","article-title":"Apical root canal microbiome associated with primary and posttreatment apical periodontitis: A systematic review","volume":"57","author":"Siqueira","year":"2024","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib20","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/etp.12060","article-title":"Present status and future directions in endodontic microbiology","volume":"30","author":"Siqueira","year":"2014","journal-title":"Endod Top"},{"key":"10.1016\/j.joen.2026.08.028_bib21","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.joen.2016.05.016","article-title":"Glove contamination during endodontic treatment is one of the sources of nosocomial endodontic propionibacterium acnes infections","volume":"42","author":"Niazi","year":"2016","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib22","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.joen.2022.01.007","article-title":"Assessing the iatrogenic contribution to contamination during root canal treatment","volume":"48","author":"Zahran","year":"2022","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0162887","article-title":"Microbiome in the apical root canal system of teeth with post-treatment apical periodontitis","volume":"11","author":"Siqueira","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.joen.2026.08.028_bib24","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1128\/jcm.32.12.3043-3045.1994","article-title":"Propionibacterium acnes as a cause of aggressive aortic valve endocarditis and importance of tissue grinding: case report and review","volume":"32","author":"G\u00fcnthard","year":"1994","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.joen.2026.08.028_bib25","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00013542-199407000-00003","article-title":"Propionibacterium acnes\u2013friend or foe?","volume":"5","author":"Eady","year":"1994","journal-title":"Rev Med Microbiol"},{"key":"10.1016\/j.joen.2026.08.028_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1128\/JCM.40.1.198-204.2002","article-title":"Quantitative analysis of mycobacterial and propionibacterial DNA in lymph nodes of Japanese and European patients with sarcoidosis","volume":"40","author":"Eishi","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.joen.2026.08.028_bib27","first-page":"477","article-title":"Severe infections caused by propionibacterium acnes: an underestimated pathogen in late postoperative infections","volume":"69","author":"Jakab","year":"1996","journal-title":"Yale J Biol Med"},{"key":"10.1016\/j.joen.2026.08.028_bib28","doi-asserted-by":"crossref","first-page":"3859","DOI":"10.1128\/JCM.01326-10","article-title":"Propionibacterium acnes and staphylococcus epidermidis isolated from refractory endodontic lesions are opportunistic pathogens","volume":"48","author":"Niazi","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.joen.2026.08.028_bib29","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/j.joen.2024.07.016","article-title":"Clinical investigation of bacteriome in primary endodontic infections with apical periodontitis using high-throughput sequencing analysis","volume":"50","author":"Alquria","year":"2024","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib30","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3892\/ijmm.2023.5263","article-title":"Interaction between apical periodontitis and systemic disease (Review)","volume":"52","author":"Ye","year":"2023","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.joen.2026.08.028_bib31","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.joen.2021.04.026","article-title":"Influence of bacterial profiles in cytokine and clinical features of endodontic disease","volume":"47","author":"Martinho","year":"2021","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib32","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1600-9657.1995.tb00476.x","article-title":"Bacteremia in conjunction with endodontic therapy","volume":"11","author":"Debelian","year":"1995","journal-title":"Dent Traumatol"},{"key":"10.1016\/j.joen.2026.08.028_bib33","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0099-2399(76)80010-6","article-title":"The incidence of bacteremias related to endodontic procedures. I. Nonsurgical endodontics","volume":"2","author":"Baumgartner","year":"1976","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib34","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0099-2399(77)80173-8","article-title":"Incidence of bacteremias related to endodontic procedures. II. Surgical endodontics","volume":"3","author":"Baumgartner","year":"1977","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib35","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jdent.2004.09.008","article-title":"Detection of bacteraemias during non-surgicalroot canal treatment","volume":"33","author":"Savarrio","year":"2005","journal-title":"J Dent"},{"key":"10.1016\/j.joen.2026.08.028_bib36","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.594150","article-title":"Role of metabolic endotoxemia in systemic inflammation and potential interventions","volume":"11","author":"Mohammad","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.joen.2026.08.028_bib37","doi-asserted-by":"crossref","first-page":"754","DOI":"10.3389\/fimmu.2018.00754","article-title":"Role of C-Reactive protein at sites of inflammation and infection","volume":"9","author":"Sproston","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.joen.2026.08.028_bib38","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1161\/01.ATV.18.8.1292","article-title":"Interleukin-1\u03b2 induces tissue- and cell type\u2013specific expression of adhesion molecules in vivo","volume":"18","author":"Tamaru","year":"1998","journal-title":"Arterio Thromb Vasc Biol"},{"key":"10.1016\/j.joen.2026.08.028_bib39","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1093\/cvr\/cvab337","article-title":"Interleukin-1\u03b2 suppression dampens inflammatory leucocyte production and uptake in atherosclerosis","volume":"118","author":"Hettwer","year":"2021","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.joen.2026.08.028_bib40","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1016\/j.jacc.2017.09.028","article-title":"Interleukin-1 beta as a target for atherosclerosis therapy","volume":"70","author":"Libby","year":"2017","journal-title":"JACC"},{"key":"10.1016\/j.joen.2026.08.028_bib41","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1161\/01.CIR.100.1.96","article-title":"C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?","volume":"100","author":"Lagrand","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.joen.2026.08.028_bib42","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1161\/01.CIR.102.18.2165","article-title":"Direct proinflammatory effect of C-reactive protein on human endothelial cells","volume":"102","author":"Pasceri","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.joen.2026.08.028_bib43","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.kint.2016.10.021","article-title":"Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease","volume":"91","author":"Mendoza","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.joen.2026.08.028_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.632260","article-title":"An overview of FGF-23 as a novel candidate biomarker of cardiovascular risk","volume":"12","author":"V\u00e1zquez-S\u00e1nchez","year":"2021","journal-title":"Front Physiol"},{"key":"10.1016\/j.joen.2026.08.028_bib45","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/MED.0000000000000294","article-title":"FGF-23 and cardiovascular disease: review of literature","volume":"23","author":"Batra","year":"2016","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"10.1016\/j.joen.2026.08.028_bib46","doi-asserted-by":"crossref","first-page":"2842S","DOI":"10.1093\/jn\/134.10.2842S","article-title":"Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the \u201cL-arginine paradox\u201d and acts as a novel cardiovascular risk factor","volume":"134","author":"B\u00f6ger","year":"2004","journal-title":"J Nutr"},{"key":"10.1016\/j.joen.2026.08.028_bib47","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1161\/CIRCULATIONAHA.120.046723","article-title":"Prevalence of infective endocarditis in streptococcal bloodstream infections is dependent on streptococcal species","volume":"142","author":"Chamat-Hedemand","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.joen.2026.08.028_bib48","doi-asserted-by":"crossref","first-page":"e963","DOI":"10.1161\/CIR.0000000000000969","article-title":"Prevention of viridans group streptococcal infective endocarditis: a scientific statement from the american heart association","volume":"143","author":"Wilson","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.joen.2026.08.028_bib49","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1186\/s12967-025-07110-0","article-title":"Successful endodontic treatment improves glucose and lipid metabolism: a longitudinal metabolomic study","volume":"23","author":"Zhang","year":"2025","journal-title":"J Transl Med"},{"key":"10.1016\/j.joen.2026.08.028_bib50","article-title":"Endothelial dysfunction in vascular complications of diabetes: a comprehensive review of mechanisms and implications","volume":"15","author":"Yang","year":"2024","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.joen.2026.08.028_bib51","doi-asserted-by":"crossref","first-page":"5617","DOI":"10.1007\/s00784-023-05183-z","article-title":"Effect of endodontic treatment on endothelial dysfunction and subclinical atherosclerosis\u2014a prospective intervention study","volume":"27","author":"Chauhan","year":"2023","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.joen.2026.08.028_bib52","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.joen.2019.03.003","article-title":"Association of apical periodontitis with cardiovascular disease via noninvasive assessment of endothelial function and subclinical atherosclerosis","volume":"45","author":"Chauhan","year":"2019","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.08.028_bib53","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.3390\/jcm9103205","article-title":"Relationship between apical periodontitis and metabolic syndrome and cardiovascular events: a cross-sectional study","volume":"9","author":"Gonz\u00e1lez-Navarro","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.joen.2026.08.028_bib54","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","article-title":"Harmonizing the metabolic syndrome","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.joen.2026.08.028_bib55","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cmet.2009.02.002","article-title":"A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance","volume":"9","author":"Newgard","year":"2009","journal-title":"Cell Metab"},{"key":"10.1016\/j.joen.2026.08.028_bib56","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCGEN.121.003330","article-title":"Association of plasma branched-chain amino acid with biomarkers of inflammation and lipid metabolism in women","volume":"14","author":"Hamaya","year":"2021","journal-title":"Circ Genom Precis Med"},{"key":"10.1016\/j.joen.2026.08.028_bib57","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/s41387-022-00213-3","article-title":"Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes","volume":"12","author":"Vanweert","year":"2022","journal-title":"Nutr Diabetes"},{"key":"10.1016\/j.joen.2026.08.028_bib58","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3389\/fendo.2020.00617","article-title":"Coordinated modulation of energy metabolism and inflammation by branched-chain amino acids and fatty acids","volume":"11","author":"Ye","year":"2020","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.joen.2026.08.028_bib59","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.3389\/fimmu.2019.02565","article-title":"Tryptophan metabolism in inflammaging: from biomarker to therapeutic target","volume":"10","author":"Sorgdrager","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.joen.2026.08.028_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.atherosclerosis.2023.117344","article-title":"Tryptophan metabolites and incident cardiovascular disease: the EPIC-Norfolk prospective population study","volume":"387","author":"Teunis","year":"2023","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.joen.2026.08.028_bib61","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/iej.14164","article-title":"Endodontic treatment modifies circulatory inflammatory mediator levels: a systematic review with meta-analysis","volume":"58","author":"Jakovljevic","year":"2025","journal-title":"Int Endod J"},{"key":"10.1016\/j.joen.2026.08.028_bib62","doi-asserted-by":"crossref","first-page":"931","DOI":"10.3390\/medicina58070931","article-title":"Association between endodontic infection, its treatment and systemic health: a narrative review","volume":"58","author":"Niazi","year":"2022","journal-title":"Medicina"},{"key":"10.1016\/j.joen.2026.08.028_bib63","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.joen.2024.05.013","article-title":"Endodontic treatment of chronic apical periodontitis ameliorates systemic inflammation and restores impaired cellular responses to insulin in an in vitro model","volume":"50","author":"Multari","year":"2024","journal-title":"J Endod"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239926004607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239926004607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:40:54Z","timestamp":1792802454000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239926004607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":63,"alternative-id":["S0099239926004607"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2026.08.028","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apical Periodontitis: A Hidden Non-Communicable Disease in Global Health - A Narrative Review of Longitudinal Research","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2026.08.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}