{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T05:27:29Z","timestamp":1794547649370,"version":"4.9.1"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100002569","name":"AAE Foundation for Endodontics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jendodon.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endodontics"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.joen.2026.10.006","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:05:58Z","timestamp":1792623958000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of On-demand Versus Scheduled Postoperative Pain Medication in Endodontic Patients with Symptomatic Apical Periodontitis: A Randomized Controlled Trial"],"prefix":"10.1016","author":[{"given":"Madeline","family":"Malueg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaclyn","family":"Danko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Drum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Nusstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al","family":"Reader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapuni","family":"Chandrasena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joen.2026.10.006_bib1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.joen.2015.12.001","article-title":"What is the effect of no endodontic debridement on postoperative pain for symptomatic teeth with pulpal necrosis?","volume":"42","author":"Sebastian","year":"2016","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.10.006_bib2","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1016\/j.joen.2011.08.026","article-title":"Efficacy of ibuprofen and ibuprofen\/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis","volume":"37","author":"Wells","year":"2011","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.10.006_bib3","doi-asserted-by":"crossref","first-page":"192","DOI":"10.2344\/anpr-66-03-06","article-title":"An evaluation of ibuprofen versus ibuprofen\/acetaminophen for postoperative endodontic pain in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis","volume":"66","author":"Stamos","year":"2019","journal-title":"Anesth Prog"},{"key":"10.1016\/j.joen.2026.10.006_bib4","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.joen.2013.09.024","article-title":"Comparison between prescription of regular or on-demand ibuprofen on postoperative pain after single-visit root canal treatment of teeth with irreversible pulpitis","volume":"40","author":"Parirokh","year":"2014","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.10.006_bib5","first-page":"114","article-title":"Efficacy of different ibuprofen formulations with two prescription methods on post endodontic pain of teeth with irreversible pulpitis: a randomized clinical trial","volume":"17","author":"Zadsirjan","year":"2022","journal-title":"Iranian Endod J"},{"key":"10.1016\/j.joen.2026.10.006_bib6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0304-3959(84)90835-2","article-title":"An experimental basis for revising the graphic rating scale for pain","volume":"19","author":"Heft","year":"1984","journal-title":"Pain"},{"key":"10.1016\/j.joen.2026.10.006_bib7","doi-asserted-by":"crossref","first-page":"816","DOI":"10.14219\/jada.archive.1978.0394","article-title":"Assessment of a dental anxiety scale","volume":"97","author":"Corah","year":"1978","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joen.2026.10.006_bib8","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1001\/jama.2017.16190","article-title":"Effect of a single dose of oral opioid and nonopioid analgesics on acute extremity pain in the emergency department","volume":"318","author":"Chang","year":"2017","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.joen.2026.10.006_bib9","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1213\/01.ANE.0000068822.10113.9E","article-title":"Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged","volume":"97","author":"Apfelbaum","year":"2003","journal-title":"Anesth Analg"},{"key":"10.1016\/j.joen.2026.10.006_bib10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.atc.2004.11.013","article-title":"Consequences of inadequate postoperative pain relief and chronic persistent postoperative pain","volume":"23","author":"Joshi","year":"2005","journal-title":"Anesthesiol Clin North Am"},{"key":"10.1016\/j.joen.2026.10.006_bib11","series-title":"Successful local anesthesia for Restorative Dentistry and Endodontics","first-page":"216,280","author":"Reader","year":"2025"},{"key":"10.1016\/j.joen.2026.10.006_bib12","first-page":"111","article-title":"A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques","volume":"50","author":"Gallatin","year":"2003","journal-title":"Anesth Prog"},{"key":"10.1016\/j.joen.2026.10.006_bib13","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.joen.2024.05.005","article-title":"Effect of back-pressure anesthesia on postoperative pain after endodontic treatment in patients with symptomatic irreversible pulpitis: randomized double-blind clinical trial","volume":"50","author":"Aggarwal","year":"2024","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.10.006_bib14","first-page":"e50","article-title":"Record analysis of permanent teeth treated as endodontic emergency visits","volume":"51","author":"Henry","year":"2025","journal-title":"J Endod"},{"key":"10.1016\/j.joen.2026.10.006_bib15","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1600-0528.1997.tb00945.x","article-title":"Gender and age differences in attitudes to dental pain and dental control","volume":"25","author":"Liddell","year":"1997","journal-title":"Community Dent Oral Epidemiol"},{"key":"10.1016\/j.joen.2026.10.006_bib16","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0304-3959(99)00128-1","article-title":"The relationship of sex and clinical pain to experimental pain responses","volume":"83","author":"Fillingim","year":"1999","journal-title":"Pain"},{"key":"10.1016\/j.joen.2026.10.006_bib17","first-page":"87","article-title":"Gender variations in the social impact of oral health","volume":"46","author":"McGrath","year":"2000","journal-title":"J Ir Dent Assoc"}],"container-title":["Journal of Endodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239926005327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0099239926005327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T05:05:03Z","timestamp":1794546303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0099239926005327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":17,"alternative-id":["S0099239926005327"],"URL":"https:\/\/doi.org\/10.1016\/j.joen.2026.10.006","relation":{},"ISSN":["0099-2399"],"issn-type":[{"value":"0099-2399","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of On-demand Versus Scheduled Postoperative Pain Medication in Endodontic Patients with Symptomatic Apical Periodontitis: A Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Endodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joen.2026.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Association of Endodontists.","name":"copyright","label":"Copyright"}]}}