{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T03:31:55Z","timestamp":1769571115917,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004878","name":"Funda\u00e7\u00e3o de Ensino e Pesquisa de Uberaba","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004878","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jogc.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Obstetrics and Gynaecology Canada"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.jogc.2021.10.008","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T11:14:09Z","timestamp":1635419649000},"page":"255-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["CIN Extension at Colposcopy: Relation to Treatment and Blood Parameters"],"prefix":"10.1016","volume":"44","author":[{"given":"Priscila Thais Silva","family":"Mantoani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9ssica Ferreira","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tainara Tavares","family":"Menchete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Millena Prata","family":"Jammal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia Antoniazi","family":"Michelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Cristina Mac\u00eado","family":"Barcelos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eddie Fernando Candido","family":"Murta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6591-7619","authenticated-orcid":false,"given":"Rosekeila Sim\u00f5es","family":"Nomelini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jogc.2021.10.008_bib0001","unstructured":"INCA. Incid\u00eancia do C\u00e2ncer no Brasil, 2020. Available at: http:\/\/www.inca.gov.br\/ Controle do c\u00e2ncer do colo do \u00fatero\/Conceito e Magnitude. Accessed on May, 2020."},{"key":"10.1016\/j.jogc.2021.10.008_bib0002","first-page":"372","article-title":"Histopathologic extent of cervical intraepithelial neoplasia 3 lesions in the atypical squamous cells of undetermined significance low-grade squamous intraepithelial lesion triage study: implications for subject safety and lead-time bias","volume":"12","author":"Sherman","year":"2003","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jogc.2021.10.008_bib0003","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.ajog.2004.01.073","article-title":"Treatment of high-grade squamous intraepithelial lesions: a 2- versus 3-step approach","volume":"190","author":"Berdichevsky","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0004","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ejogrb.2020.11.044","article-title":"Laboratory parameters as predictors of prognosis in uterine cervical neoplasia","volume":"256","author":"Lima","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0005","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/IGC.0b013e3181ef8deb","article-title":"Systemic leukocyte alterations are associated with invasive uterine cervical cancer","volume":"20","author":"Tavares-Murta","year":"2010","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.jogc.2021.10.008_bib0006","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1097\/AOG.0b013e318254f90c","article-title":"2011 colposcopic terminology of the International Federation for Cervical Pathology and Colposcopy","volume":"120","author":"Bornstein","year":"2012","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0007","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3802\/jgo.2010.21.2.87","article-title":"Absence of dysplasia in the excised cervix by a loop electrosurgical excision procedure in the treatment of cervical intraepithelial neoplasia","volume":"21","author":"Ryu","year":"2010","journal-title":"J Gynecol Oncol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0008","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00128360-200607000-00018","article-title":"Predicting \"no residual dysplasia\" in loop electrosurgical excision procedure specimens","volume":"10","author":"Kinney","year":"2006","journal-title":"J Low Genit Tract Dis"},{"key":"10.1016\/j.jogc.2021.10.008_bib0009","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ygyno.2012.10.020","article-title":"Predictors of absence of cervical intraepithelial neoplasia in the conization specimen","volume":"128","author":"Rodriguez-Manfredi","year":"2013","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0010","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/LGT.0000000000000019","article-title":"Do colposcopically directed biopsy and endocervical curettage serve to induce regression of cervical intraepithelial neoplasia?","volume":"18","author":"Diedrich","year":"2014","journal-title":"J Low Genit Tract Dis"},{"key":"10.1016\/j.jogc.2021.10.008_bib0011","first-page":"996","article-title":"The significance of positive margins in loop electrosurgical cone biopsies","volume":"84","author":"Felix","year":"1994","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0012","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1590\/S1516-31802012000200009","article-title":"Risk of persistent high-grade squamous intraepithelial lesion after electrosurgical excisional treatment with positive margins: a meta-analysis","volume":"130","author":"Oliveira","year":"2012","journal-title":"Sao Paulo Med J"},{"key":"10.1016\/j.jogc.2021.10.008_bib0013","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0140-6736(06)68181-6","article-title":"Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis","volume":"367","author":"Kyrgiou","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jogc.2021.10.008_bib0014","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ajog.2011.01.003","article-title":"Cervical conization and the risk of preterm delivery","volume":"205","author":"Bevis","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0015","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1136\/jcp.2004.025072","article-title":"A shift to a peripheral Th2-type cytokine pattern during the carcinogenesis of cervical cancer becomes manifest in CIN III lesions","volume":"58","author":"Bais","year":"2005","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.jogc.2021.10.008_bib0016","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1093\/jnci\/92.10.818","article-title":"Human papillomavirus DNA testing for cervical cancer screening in low-resource settings","volume":"92","author":"Kuhn","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jogc.2021.10.008_bib0017","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1054\/bjoc.2001.1845","article-title":"Human papillomavirus testing in primary screening for the detection of high-grade cervical lesions: a study of 7932 women","volume":"84","author":"Clavel","year":"2001","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jogc.2021.10.008_bib0018","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/oxfordjournals.jncimonographs.a003488","article-title":"Chapter 13: primary screening of cervical cancer with human papillomavirus tests","author":"Franco","year":"2003","journal-title":"J Natl Cancer Inst Monogr"},{"key":"10.1016\/j.jogc.2021.10.008_bib0019","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1590\/S0102-311X2007000600006","article-title":"Utilization of the molecular biology method for diagnosing human papillomavirus in the female lower tract, for uterine cervical cancer prevention in university hospital","volume":"23","author":"Nomelini","year":"2007","journal-title":"Cad Saude Publica"},{"key":"10.1016\/j.jogc.2021.10.008_bib0020","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1590\/S0102-311X2012001100004","article-title":"Prevention of cervical cancer in women with ASCUS in the Brazilian Unified National Health System: cost-effectiveness of the molecular biology method for HPV detection","volume":"28","author":"Nomelini","year":"2012","journal-title":"Cad Saude Publica"}],"container-title":["Journal of Obstetrics and Gynaecology Canada"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216321007696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216321007696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:40:01Z","timestamp":1761666001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1701216321007696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S1701216321007696"],"URL":"https:\/\/doi.org\/10.1016\/j.jogc.2021.10.008","relation":{},"ISSN":["1701-2163"],"issn-type":[{"value":"1701-2163","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CIN Extension at Colposcopy: Relation to Treatment and Blood Parameters","name":"articletitle","label":"Article Title"},{"value":"Journal of Obstetrics and Gynaecology Canada","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jogc.2021.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Society of Obstetricians and Gynaecologists of Canada\/La Soci\u00e9t\u00e9 des obst\u00e9triciens et gyn\u00e9cologues du Canada. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}