{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:52:13Z","timestamp":1772585533545,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-77549"],"award-info":[{"award-number":["MOP-77549"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jogc.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Obstetrics and Gynaecology Canada"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jogc.2023.102342","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T17:36:56Z","timestamp":1704217016000},"page":"102342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Increased Y Chromosome Microdeletions in Cord Blood of Male Newborns From Assisted Reproductive Technology Compared to Natural Conception"],"prefix":"10.1016","volume":"46","author":[{"given":"Richard","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paloma","family":"Stanar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenny","family":"Louie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9753-0653","authenticated-orcid":false,"given":"Sai","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jogc.2023.102342_bib1","unstructured":"Gunby J. Assisted reproductive technologies (ART) in Canada: 2012 results from the Canadian ART Register."},{"key":"10.1016\/j.jogc.2023.102342_bib2","series-title":"ESHRE ART fact sheet","year":"2022"},{"key":"10.1016\/j.jogc.2023.102342_bib3","first-page":"23","article-title":"In\u00a0vitro fertilization technology and child health","volume":"117","author":"von Wolff","year":"2020","journal-title":"Dtsch \u00c4rztebl Int"},{"key":"10.1016\/j.jogc.2023.102342_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2016.04.036","article-title":"Altered DNA methylation and expression of PLAGL1 in cord blood from assisted reproductive technology pregnancies compared with natural conceptions","volume":"106","author":"Vincent","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jogc.2023.102342_bib5","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/hmg\/ddy321","article-title":"Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome","volume":"28","author":"Choufani","year":"2019","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib6","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1038\/nature05977","article-title":"Expandable DNA repeats and human disease","volume":"447","author":"Mirkin","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jogc.2023.102342_bib7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/ng1001-131","article-title":"Intra-cytoplasmic sperm injection and infertility","volume":"29","author":"Faddy","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib8","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.1093\/humrep\/13.12.3332","article-title":"Y\u00a0chromosome deletions in azoospermic and severely oligozoospermic men undergoing intracytoplasmic sperm injection after testicular sperm extraction","volume":"13","author":"Silber","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jogc.2023.102342_bib9","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/hmg\/5.7.933","article-title":"Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11","volume":"5","author":"Vogt","year":"1996","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib10","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.2741\/2032","article-title":"Y\u00a0chromosome and male infertility: update, 2006","volume":"11","author":"Krausz","year":"2006","journal-title":"Front Biosci"},{"key":"10.1016\/j.jogc.2023.102342_bib11","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/ejhg.2013.253","article-title":"Clinical relevance of Y-linked CNV screening in male infertility: new insights based on the 8-year experience of a diagnostic genetic laboratory","volume":"22","author":"Lo Giacco","year":"2014","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib12","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1038\/nature01722","article-title":"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes","volume":"423","author":"Skaletsky","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jogc.2023.102342_bib13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.2047-2927.2013.00173.x","article-title":"EAA\/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions: state-of-the-art 2013","volume":"2","author":"Krausz","year":"2014","journal-title":"Andrology"},{"key":"10.1016\/j.jogc.2023.102342_bib14","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1136\/jmg.37.10.752","article-title":"Divergent outcomes of intrachromosomal recombination on the human Y chromosome: male infertility and recurrent polymorphism","volume":"37","author":"Blanco","year":"2000","journal-title":"J\u00a0Med Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib15","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.fertnstert.2012.03.034","article-title":"Screening for partial AZFa microdeletions in the Y chromosome of infertile men: is it of clinical relevance?","volume":"98","author":"Kleiman","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jogc.2023.102342_bib16","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/ng757","article-title":"The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men","volume":"29","author":"Kuroda-Kawaguchi","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib17","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1093\/humrep\/deh186","article-title":"Case Report: natural transmission of an AZFc Y-chromosomal microdeletion from father to his sons","volume":"19","author":"K\u00fchnert","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jogc.2023.102342_bib18","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.siny.2014.03.002","article-title":"The impact of assisted reproductive technologies on intra-uterine growth and birth defects in singletons","volume":"19","author":"Hansen","year":"2014","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jogc.2023.102342_bib19","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1093\/molehr\/2.12.943","article-title":"The incidence and possible relevance of Y-linked microdeletions in babies born after intracytoplasmic sperm injection and their infertile fathers","volume":"2","author":"Kent-First","year":"1996","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.jogc.2023.102342_bib20","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.fertnstert.2005.10.034","article-title":"Intracytoplasmic sperm injection may lead to vertical transmission, expansion, and de novo occurrence of Y-chromosome microdeletions in male fetuses","volume":"85","author":"Lee","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jogc.2023.102342_bib21","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/pd.1772","article-title":"Molecular and cytogenetic investigation of Y chromosome deletions over three generations facilitated by intracytoplasmic sperm injection","volume":"27","author":"Minor","year":"2007","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.jogc.2023.102342_bib22","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.fertnstert.2007.06.004","article-title":"Assisted reproductive technology may increase clinical mutation detection in male offspring","volume":"90","author":"Feng","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jogc.2023.102342_bib23","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1093\/humrep\/17.11.2813","article-title":"Clinical characterization of 42 oligospermic or azoospermic men with microdeletion of the AZFc region of the Y chromosome, and of 18 children conceived via ICSI","volume":"17","author":"Oates","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jogc.2023.102342_bib24","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1093\/oxfordjournals.hmg.a018920","article-title":"Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses","volume":"9","author":"Sun","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib25","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s100380200066","article-title":"Transmission of Y chromosomal microdeletions from father to son through intracytoplasmic sperm injection","volume":"47","author":"Komori","year":"2002","journal-title":"J\u00a0Hum Genet"},{"key":"10.1016\/j.jogc.2023.102342_bib26","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1210\/jc.2006-1981","article-title":"Molecular and clinical characterization of Y chromosome microdeletions in infertile men: A 10-year experience in Italy","volume":"92","author":"Ferlin","year":"2007","journal-title":"J\u00a0Clin Endocrinol Metab"}],"container-title":["Journal of Obstetrics and Gynaecology Canada"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216323007491?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216323007491?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T12:25:38Z","timestamp":1714566338000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1701216323007491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S1701216323007491"],"URL":"https:\/\/doi.org\/10.1016\/j.jogc.2023.102342","relation":{},"ISSN":["1701-2163"],"issn-type":[{"value":"1701-2163","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased Y Chromosome Microdeletions in Cord Blood of Male Newborns From Assisted Reproductive Technology Compared to Natural Conception","name":"articletitle","label":"Article Title"},{"value":"Journal of Obstetrics and Gynaecology Canada","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jogc.2023.102342","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Society of Obstetricians and Gynaecologists of Canada\/La Soci\u00e9t\u00e9 des obst\u00e9triciens et gyn\u00e9cologues du Canada. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102342"}}